Harriëtte J. van Esch, MD1,2,3; Lia van Zuylen, MD, PhD1,4; Eric C. T. Geijteman, MD, PhD1; Esther Oomen-de Hoop, PhD1; Bregje A. A. Huisman, MD5; Heike S. Noordzij-Nooteboom, MD6; Renske Boogaard, RN7; Agnes van der Heide, MD, PhD2; Carin C. D. van der Rijt, MD, PhD1
doi : 10.1001/jama.2021.14785
JAMA. 2021;326(13):1268-1276
Death rattle, defined as noisy breathing caused by the presence of mucus in the respiratory tract, is relatively common among dying patients. Although clinical guidelines recommend anticholinergic drugs to reduce the death rattle after nonpharmacological measures fail, evidence regarding their efficacy is lacking. Given that anticholinergics only decrease mucus production, it is unknown whether prophylactic application may be more appropriate.
David Jiménez, MD, PhD1,2,3; Alvar Agustí, MD, PhD4; Eva Tabernero, MD5; Luis Jara-Palomares, MD, PhD6; Ascensión Hernando, MD, PhD7; Pedro Ruiz-Artacho, MD, PhD3,8; Gregorio Pérez-Peñate, MD, PhD9; Agustina Rivas-Guerrero, MD10; María Jesús Rodríguez-Nieto, MD, PhD3,11; Aitor Ballaz, MD12; Ramón Agüero, MD13; Sonia Jiménez, MD14; Myriam Calle-Rubio, MD, PhD15; Raquel López-Reyes, MD16; Pedro Marcos-Rodríguez, MD17; Deisy Barrios, MD, PhD1; Carmen Rodríguez, MD1; Alfonso Muriel, PhD18; Laurent Bertoletti, MD, PhD19; Francis Couturaud, MD, PhD20; Menno Huisman, MD, PhD21; José Luis Lobo, MD10; Roger D. Yusen, MD22; Behnood Bikdeli, MD, MS23,24,25; Manuel Monreal, MD, PhD3,26; Remedios Otero, MD, PhD3,6; for the SLICE Trial Group
doi : 10.1001/jama.2021.14846
JAMA. 2021;326(13):1277-1285
Active search for pulmonary embolism (PE) may improve outcomes in patients hospitalized for exacerbations of chronic obstructive pulmonary disease (COPD).
Jiang He, MD, PhD1,2,3; Zhengbao Zhu, MD, PhD1,4; Joshua D. Bundy, PhD, MPH1,2; Kirsten S. Dorans, ScD1,2; Jing Chen, MD, MSc1,2,3; L. Lee Hamm, MD1,2,3
doi : 10.1001/jama.2021.15187
JAMA. 2021;326(13):1286-1298
After decades of decline, the US cardiovascular disease mortality rate flattened after 2010, and racial and ethnic differences in cardiovascular disease mortality persisted.
Daniel S. Budnitz, MD, MPH1; Nadine Shehab, PharmD, MPH1,2; Maribeth C. Lovegrove, MPH1; Andrew I. Geller, MD1; Jennifer N. Lind, PharmD, MPH1; Daniel A. Pollock, MD1
doi : 10.1001/jama.2021.13844
JAMA. 2021;326(13):1299-1309
Assessing the scope of acute medication harms to patients should include both therapeutic and nontherapeutic medication use.
Joshua R. Vest, PhD, MPH1,2; Justin Blackburn, PhD1; Shama Cash-Goldwasser, MD, MPH3; Eleanor Peters Bergquist, PhD, MSPH, MA3; Peter J. Embi, MD, MS2,4
doi : 10.1001/jama.2021.14057
JAMA. 2021;326(13):1324-1325
Hannah T. Neprash, PhD1; Michael E. Chernew, PhD2
doi : 10.1001/jama.2021.16324
JAMA. 2021;326(13):1325-1328
Antony J. Blinken, JD1; Xavier Becerra, JD2
doi : 10.1001/jama.2021.15611
JAMA. 2021;326(13):1255-1256
Lawrence O. Gostin, JD1; Sam F. Halabi, JD, MPhil1; Kevin A. Klock, JD2
doi : 10.1001/jama.2021.16104
JAMA. 2021;326(13):1257-1258
Abby Rosenberg, MD, MS, MA1,2,3; Robert M Arnold, MD4,5; Yael Schenker, MD, MAS4,5
doi : 10.1001/jama.2021.14802
JAMA. 2021;326(13):1259-1260
Jared R. Lowe, MD1,2; Laura C. Hanson, MD, MPH2,3
doi : 10.1001/jama.2021.9846
JAMA. 2021;326(13):1263-1265
John P. A. Ioannidis, MD, DSc1,2; Michael Berkwits, MD, MSCE3; Annette Flanagin, RN, MA3; Fiona Godlee, MBBChir4; Theodora Bloom, PhD4
doi : 10.1001/jama.2021.16596
JAMA. 2021;326(13):1265-1267
Amanda Muir, MD, MSTR1; Gary W. Falk, MD, MS2
doi : 10.1001/jama.2021.14920
JAMA. 2021;326(13):1310-1318
Eosinophilic esophagitis (EoE) is a chronic immune-mediated inflammatory disease of the esophagus that affects an estimated 34.4/100?000 people in Europe and North America. EoE affects both children and adults, and causes dysphagia, food impaction of the esophagus, and esophageal strictures.
Marlene L. Durand, MD1,2; Miriam Baron Barshak, MD1; James Chodosh, MD, MPH2
doi : 10.1001/jama.2021.0424
JAMA. 2021;326(13):1319-1320
Osman Ahmed, MD1; Adam S. Cifu, MD1; Jonathan Paul, MD1
doi : 10.1001/jama.2021.9262
JAMA. 2021;326(13):1321-1322
Rita Rubin, MA
doi : 10.1001/jama.2021.13462
JAMA. 2021;326(13):1241-1243
Jennifer Abbasi
doi : 10.1001/jama.2021.14017
JAMA. 2021;326(13):1244-1245
Anita Slomski
doi : 10.1001/jama.2021.16374
JAMA. 2021;326(13):1246
Anita Slomski
doi : 10.1001/jama.2021.15425
JAMA. 2021;326(13):1246
Anita Slomski
doi : 10.1001/jama.2021.16375
JAMA. 2021;326(13):1246
Anita Slomski
doi : 10.1001/jama.2021.16376
JAMA. 2021;326(13):1246
Rebecca Voelker, MSJ
doi : 10.1001/jama.2021.16443
JAMA. 2021;326(13):1247
Rebecca Voelker, MS
doi : 10.1001/jama.2021.16089
JAMA. 2021;326(13):1247
Rebecca Voelker, MSJ
doi : 10.1001/jama.2021.16444
JAMA. 2021;326(13):1247
Nick Love, MD, PhD1,2,3; Yuichi J. Shimada, MD, MPH4
doi : 10.1001/jama.2021.6972
JAMA. 2021;326(13):1238-1240
Zhaoping Li, MD, PhD1; David Heber, MD, PhD1
doi : 10.1001/jama.2020.15140
JAMA. 2021;326(13):1338
Shida Haghighat, MD, MPH1; Daniel A. Sussman, MD, MSPH1; Amar Deshpande, MD1
doi : 10.1001/jama.2021.13466
JAMA. 2021;326(13):1328
Michael J. Barry, MD1; Karina Davidson, PhD, MASc2; Carol M. Mangione, MD, MSPH3
doi : 10.1001/jama.2021.13469
JAMA. 2021;326(13):1328-1329
Kevin Cowart, PharmD, MPH1; Nicholas W. Carris, PharmD1
doi : 10.1001/jama.2021.13472
JAMA. 2021;326(13):1329-1330
Wellbert Hernández-Núñez, MD1; Jesús Zacarías Villareal-Pérez, MD2; René Rodríguez-Gutiérrez, MD, MSc, PhD3
doi : 10.1001/jama.2021.13475
JAMA. 2021;326(13):1330
Thomas W. Martens, MD1; Roy W. Beck, MD, PhD2; Richard M. Bergenstal, MD3
doi : 10.1001/jama.2021.13478
JAMA. 2021;326(13):1330-1331
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