Srikanth Vallurupalli MD,Negar Salehi MD,Shiv Agarwal MD,Rimsha Hasan MD,Atif Hassan MD,Aisha Siraj MD,Mohammed Eid Madmani MD,Rahil Rafeedheen MD,Mohamed Ayan MD,Malek Al-Hawwas MD,Abdul Hakeem MD,Barry F. Uretsky MD
doi : 10.1002/ccd.29945
Volume 98, Issue 6 p. 1021-1026
Resting coronary blood flow approximates flow with maximal vasodilation in very severe coronary stenosis. We studied the incidence of exhausted vasodilatory reserve by FFR, its clinical characteristics and long-term prognosis after FFR guided percutaneous coronary intervention (PCI).
Hernan Mejia-Renteria MD, PhD,Joo Myung Lee MD, MPH, PhD,Ki-Hong Choi MD,Seung-Hun Lee MD, PhD,Lin Wang MD,Tsunekazu Kakuta MD, PhD,Bon-Kwon Koo MD, PhD,Javier Escaned MD, PhD
doi : 10.1002/ccd.29863
Volume 98, Issue 6 p. 1027-1037
We aimed to develop a novel wire- and adenosine-free microcirculatory resistive index from functional angiography (angio-IMR) to estimate coronary microcirculatory resistance, and to investigate how this method can improve clinical interpretation of physiological stenosis assessment with quantitative flow ratio (QFR).
Enrico Cerrato MD,Davide Belliggiano MD,Giorgio Quadri MD,Andrea Erriquez MD,Matteo Anselmino MD, PhD,Alicia Quirós PhD,Alfonso Franzè MD,Fabio Ferrari MD,Cristina Rolfo MD,Hernan Mejia-Renteria MD,Javier Escaned MD, PhD,Nieves Gonzalo MD, PhD,Gianluca Campo MD, PhD,Ferdinando Varbella MD
doi : 10.1002/ccd.29397
Volume 98, Issue 6 p. 1038-1046
No data are currently available on the process of vessel healing and long-term physiological results after implantation of resorbable magnesium-made scaffold (RMS) in human coronary arteries.
Tomoyo Sugiyama MD, PhD,Yoshinori Kanno MD,Rikuta Hamaya MD,Yoshihisa Kanaji MD, PhD,Masahiro Hoshino MD,Tadashi Murai MD, PhD,Tetsumin Lee MD, PhD,Taishi Yonetsu MD,Tetsuo Sasano MD, PhD,Tsunekazu Kakuta MD, PhD
doi : 10.1002/ccd.29388
Volume 98, Issue 6 p. 1047-1056
We aimed to evaluate the determinants of visual-functional mismatches between quantitative coronary angiography (QCA) and the quantitative flow ratio (QFR).
Matteo Tebaldi MD,Simone Biscaglia MD,Andrea Erriquez MD,Carlo Penzo MD,Carlo Tumscitz MD,Alessandra Scoccia MD,Giorgio Quadri MD,Giorgio Sacchetta MD,Anna Folla MSN,Giuseppe Vadalà MD,Luca Fileti MD,Gianluca Campo MD
doi : 10.1002/ccd.29380
Volume 98, Issue 6 p. 1057-1065
To investigate the correlation between quantitative flow ratio (QFR), Pd/Pa, diastolic hyperemia-free ratio (DFR) and fractional flow reserve (FFR, gold standard) in non-culprit lesion (NCL) of patients with non ST-segment elevation myocardial infarction (NSTEMI).
Sameer Mehta MD, MBA,Cindy L. Grines MD,Roberto Botelho MD, PhD, MBA,Francisco Fernandez MBA,Jamil Cade MD,Cesar Dusilek MD,Mauricio Prudente MD,Ricardo Cavalcanti MD,Carlos Campos MD,Marco Alcocer Gamba MD
doi : 10.1002/ccd.29896
Volume 98, Issue 6 p. 1066-1071
Developing countries struggle to diagnose and treat ST-segment elevation myocardial infarction (STEMI) patients in a timely manner, and subsequent outcomes are suboptimal.
Markus Jäckel MD,Viviane Zotzmann MD,Tobias Wengenmayer MD,Daniel Duerschmied MD,Paul M. Biever MD,Derek Spieler MD,Constantin von zur Mühlen MD,Peter Stachon MD,Christoph Bode MD,Dawid L. Staudacher MD
doi : 10.1002/ccd.29275
Volume 98, Issue 6 p. 1072-1081
This study aimed to identify the incidence and potential risk factors for delirium after myocardial infarction (MI).
Mohamad Lazkani MD,Byomesh Tripathi MD,Philip Dattilo MD
doi : 10.1002/ccd.29394
Volume 98, Issue 6 p. 1082-1094
Percutaneous coronary intervention (PCI) is well established for the treatment of obstructive coronary artery disease. This study was performed to assess the impact of in-hospital mortality and 30-day readmission with intracoronary imaging as an adjunct to baseline coronary angiography.
Jaya Chandrasekhar MBBS, MS, PhD,Deborah N. Kalkman MD, PhD,Samantha Sartori PhD,Usman Baber MD, MS,Moritz Blum MS,Melissa B. Aquino MS,Pier Woudstra MD,Marcel A. Beijk MD, PhD,Jan G. Tijssen PhD,Karel T. Koch MD, PhD,George D. Dangas MD, PhD,Antonio Colombo MD,Robbert J. de Winter MD, PhD,Roxana Mehran MD,MASCOT and REMEDEE investigators
doi : 10.1002/ccd.29270
Volume 98, Issue 6 p. 1095-1101
Chronic kidney disease (CKD) patients undergoing percutaneous coronary intervention (PCI) experience greater ischemic events including clinically driven target lesion revascularization (CD-TLR). Whether the COMBO biodegradable-polymer sirolimus-eluting stent promotes better outcomes in these patients by virtue of endothelial progenitor cell capture technology is unknown.
Alexandre Abizaid MD, PhD,Sasko Kedev MD, PhD,Rosli Bin Mohd Ali MD,Teguh Santoso MD,Angel Cequier MD,Robert-Jan Van Geuns van Geuns MD, PhD,Bernard Chevalier MD,Farrel Hellig MD,Ricardo Costa MD, PhD,Yoshinobu Onuma MD, PhD,Jose Ribamar Costa Jr MD, PhD,Patrick Serruys MD, PhD,Sripal Bangalore MD, MHA, FACC, FSCAI
doi : 10.1002/ccd.29396
Volume 98, Issue 6 p. 1102-1110
This study explores the safety and efficacy of thin strut MeRes100 sirolimus-eluting bioresorbable vascular scaffold (BRS) in patients with de novo coronary artery lesions.
Ridhima Goel MD,Davide Cao MD,Rishi Chandiramani MD,Anastasios Roumeliotis MD,Moritz Blum BS,Deepak L. Bhatt MD, MPH,Dominick J. Angiolillo MD, PhD,Junbo Ge MD,Ashok Seth MD, FRCP, DSc,Shigeru Saito MD,Mitchell Krucoff MD,Ken Kozuma MD, PhD,Rajendra M. Makkar MD,Sripal Bangalore MD, MHA,Lijuan Wang PhD,Kai Koo PhD,Franz-Josef Neumann MD,James Hermiller MD,Giulio Stefanini MD, PhD,Marco Valgimigli MD, PhD,Roxana Mehran MD
doi : 10.1002/ccd.29314
Volume 98, Issue 6 p. 1111-1119
To investigate the impact of ischemic and bleeding risk factors on long-term clinical outcomes of patients with diabetes mellitus (DM) undergoing percutaneous coronary intervention (PCI) with everolimus-eluting stents.
Pablo Michel MD,Javier Amione-Guerra MD,Omar Sheikh MD,Lauren C. Jameson MS,Shweta Bansal MD,Anand Prasad MD
doi : 10.1002/ccd.29387
Volume 98, Issue 6 p. 1120-1132
To perform a detailed analysis of published data regarding intravascular volume expansion to prevent contrast-associated acute kidney injury (CA-AKI) and to determine if an ideal dose of IV fluids can be recommended.
Sumon Roy MD,Ravi Choxi MD,Melissa Wasilewski MD,Ion S. Jovin MD
doi : 10.1002/ccd.29771
Volume 98, Issue 6 p. 1133-1137
Transradial access of the vascular system for coronary angiography and percutaneous coronary intervention has become the primary approach in several cardiac catheterization laboratories across the world. The paradigm shift from transfemoral access has been driven by improved outcomes in patients undergoing these cardiac procedures by transradial access. Radial artery occlusion is the most common vascular complication of transradial coronary procedures. Only a few studies have reported on the optimal treatment of radial artery occlusion, with ulnar artery compression and anticoagulation, especially with low-molecular-weight heparin, having shown the best results. In this case series, four patients who were found to have evidence of post-cardiac catheterization radial artery occlusion on ultrasound imaging were treated with a 30-day course of apixaban. Three of the four patients showed complete resolution of radial artery occlusion with addition of apixaban to current standard therapeutic strategies. This case series shows that treatment with novel oral anticoagulants can be an alternative and more convenient option compared to subcutaneous injection of low-molecular heparin for anticoagulation in patients with post-coronary angiography radial artery occlusion.
Konstantinos Marmagkiolis MD, MBA, FACC, FSCAI,Jaime A. Caballero MD,Mehmet Cilingiroglu MD,Cezar Iliescu MD
doi : 10.1002/ccd.29804
Volume 98, Issue 6 p. 1138-1140
The use of two arterial vascular accesses is now the standard of care in chronic total occlusion (CTO) percutaneous coronary interventions (PCI). When Impella support is needed, an additional vascular access may be necessary. We describe the first-in-man single-access, dual injection technique (SADIT). The Impella CP device was inserted in the left ventricle in the standard fashion. Subsequently, a 6 French sheath was placed at the “10 o clock” position and a second 4 French sheath was at the “5 o clock” position. This technique obviates the need for additional arterial access sites and potentially risk of complications. The SADIT technique is a simple way to perform high-risk, Impella-assisted coronary revascularization procedures necessitating dual coronary injections like CTO interventions. This strategy avoids unnecessary vascular complications from multiple access sites.
Andrew M. Goldsweig MD, MS,Eric Secemsky MD, MSc,Rishi Wadhera MD, MPP, MPhil,David J. Cohen MD, MSc
doi : 10.1002/ccd.29822
Volume 98, Issue 6 p. 1141-1143
Rhian E. Davies DO, MS,Jeremy D. Rier DO,Margaret McEntegart MD, PhD,Robert F. Riley MD, MS,Kathleen Kearney MD,William Lombardi MD
doi : 10.1002/ccd.29924
Volume 98, Issue 6 p. 1144-1151
Giorgio A. Medranda MD,Rebecca Torguson MPH,Ron Waksman MD
doi : 10.1002/ccd.29730
Volume 98, Issue 6 p. 1152-1158
Refractory angina is considered a devastating condition with limited medical and therapeutic options. The Neovasc Reducer device, when implanted in the coronary sinus, is designed to alleviate anginal symptoms. However, the available clinical data are sparse. The US Food and Drug Administration (FDA) assembled the Circulatory Systems Devices Panel to discuss the Reducer's safety and effectiveness. Because of the coronavirus disease 2019 pandemic, this meeting was held virtually. In this manuscript, we detail the deliberation and discussion among the circulatory panel members, including their final vote.
Michael L. O'Byrne MD MSCE,Andrew C. Glatz MD MSCE
doi : 10.1002/ccd.29925
Volume 98, Issue 6 p. 1159-1166
Measuring the effect of a treatment on outcomes is an important goal for research in pediatric/congenital interventional cardiology. The breadth of anatomic and physiologic variations, patient ages, and genetic syndromes and noncardiac comorbid conditions all represent sources of potential confounding and effect modification that are major obstacles to this goal. If not accounted for, these factors can obscure the “true” treatment effect and lead to spurious conclusions about the relative efficacy and/or safety of therapies. In this review, we discuss the importance of confounding and effect modification in pediatric/congenital interventional cardiology research. We define these terms and discuss strategies (both in study design and data analysis) to mitigate error introduced by confounding and effect modification. The importance of confounding by indication in pediatric/congenital cardiology is discussed along with specific methods to address it.
Giuliano Costa MD,Paola D'Errigo RS,Stefano Rosato RS,Roberto Valvo MD,Fausto Biancari MD, PhD,Corrado Tamburino MD, PhD,Francesco Cerza RS, PhD,Stefano Domenico Cicala RS,Fulvia Seccareccia RS,Marco Barbanti MD,for the OBSERVANT Research Group
doi : 10.1002/ccd.29701
Volume 98, Issue 6 p. 1167-1176
To compare clinical outcomes of balloon-expandable (BE) and self-expanding (SE) transcatheter aortic valves (TAVs) up to 5?years.
Hemang B. Panchal MD, MPH,Gregg W. Stone MD,Anshul Saxena PhD,Zoran Bursac PhD,Emir Veledar PhD,Arun Nagabandi MD,Charles J. Davidson MD,Martin B. Leon MD,Nirat Beohar MD
doi : 10.1002/ccd.29712
Volume 98, Issue 6 p. 1177-1184
To assess the outcomes following transcatheter edge-to-edge mitral valve repair (TMVr) in patients with chronic kidney disease (CKD).
Marvin H. Eng MD,Amr E. Abbas MD,Rebecca T. Hahn MD,James Lee MD,Dee Dee Wang MD,Mackram F. Eleid MD,William W. O'Neill MD
doi : 10.1002/ccd.29756
Volume 98, Issue 6 p. 1185-1192
Small balloon expandable valves have higher echocardiographic transvalvular gradients and rates of prosthesis-patient mismatch (PPM) compared to larger valves. However, the impact of these echocardiographic findings on clinical outcomes is unknown. We sought to determine the clinical outcomes of 20?mm SAPIEN 3 (S3 BEV) compared to larger S3 BEV in relation to echocardiographic hemodynamics.
Marvin H. Eng MD,Faraj Kargoli MD, MPH,Dee Dee Wang MD,Tiberio M. Frisoli MD,James C. Lee MD,Pedro S. Villablanca MD MS,Hassan Nemeh MD,Adam B. Greenbaum MD,Mayra Guerrero MD,Brian P. O'Neill MD,Janet Wyman DNP,William O'Neill MD
doi : 10.1002/ccd.29783
Volume 98, Issue 6 p. 1193-1203
Due to elevated surgical risk, transcatheter mitral valve replacement (TMVR) is used as an alternative for treating failed bioprosthetic valves, annuloplasty repairs and mitral annular calcification (MAC). We report the procedural and longitudinal outcomes for each subtype: Mitral valve-in-valve (MVIV), mitral valve-in-ring (MViR), and valve-in-MAC (ViMAC).
Mathias Wolfrum MD,Federico Moccetti MD,Jarkko Piuhola MD,Heidi Lehtola MD,José Antonio Baz MD,Andrés Iñiguez MD,Lokien X. van Nunen MD,Pim A. L. Tonino MD,Matti Niemelä MD,Stefan Toggweiler MD
doi : 10.1002/ccd.29833
Volume 98, Issue 6 p. 1204-1209
We aimed to determine the safety and efficacy of the Allegra transcatheter heart valve (THV) for the treatment of severe aortic valve stenosis in a large patient population treated under real-world conditions.
Frans J. Beerkens MD,Ranbir Singh MD,Davide Cao MD,Bimmer E. Claessen MD, PhD,Johny Nicolas MD,Samantha Sartori PhD,Clayton Snyder MPH,Anton Camaj MD, MS,Gennaro Giustino MD,David Power MD,Victor Razuk MD,Davis Jones MD,Anne H. Tavenier MD,Carlo Andrea Pivato MD,Matteo Nardin MD,Mauro Chiarito MD,Prakash Krishnan MD,Nitin Barman MD,Usman Baber MD,Joseph Sweeny MD,George Dangas MD, PhD,Samin K. Sharma MD,Roxana Mehran MD,Annapoorna Kini MD
doi : 10.1002/ccd.29935
Volume 98, Issue 6 p. E785-E795
To evaluate and compare characteristics and clinical outcomes of percutaneous coronary intervention (PCI) among target vessel types in patients with a prior coronary artery bypass graft (CABG) surgery.
Takeshi Yamada MD,Soichiro Washimi MD,Sho Hashimoto MD,Norimasa Taniguchi MD,Shunsuke Nakajima MD,Tetsuya Hata MD,Akihiko Takahashi MD
doi : 10.1002/ccd.29938
Volume 98, Issue 6 p. E796-E801
Distal transradial access (dTRA) is a novel alternative to conventional radial artery access for coronary catheterization. However, the feasibility and safety of repeated use of dTRA have not been fully elucidated. This study aimed to evaluate the feasibility and safety of the repeated use of dTRA for coronary angiography and intervention in the same arm. A total of 1717 patients underwent angiography or angioplasty via dTRA. We retrospectively analyzed the catheterization records of patients who underwent repeated puncture of the distal radial artery in the same arm. The incidence of successive applications of dTRA and the reasons for dropout were retrospectively investigated. A total of 416 patients, including three who underwent coronary catheterization with the bilateral dTRA in the initial attempt were analyzed. A 3-, 4-, 5-, or 6-French sheath or sheathless guide catheter was used in the initial procedure. A maximum of four successive coronary catheterization procedures were performed. The second procedure with dTRA on the same arm was successfully performed in 395 cases (94.3%), with a successive rate of 89.6% for both the third and fourth dTRA procedures. Conversion to another approach site (n = 30) was attributed to radial artery occlusion (n = 9), narrowing of the distal radial artery (n = 19), and puncture failure (n = 2). The current data indicate that the repeated use of dTRA is safe and feasible, and this approach may become a standard approach site in the future.
Waqas Ullah MD,Mohamed Zghouzi MD,Bachar Ahmad MS,Abdul-Rahman M. Suleiman,Salman Zahid MD,Mohammed Faisaluddin,Mukhlis Alabdalrazzak,Yasar Sattar MD,Ankur Kalra MD,Samir Kapadia MD,David L. Fischman MD,Emmanouil S. Brilakis MD, PhD,Mamas A. Mamas BMBCh, MA, DPhil, FRCP,M. Chadi Alraies MD, MPH
doi : 10.1002/ccd.29953
Volume 98, Issue 6 p. E802-E813
The relative safety and efficacy of polymer-free (PF) versus polymer-coated (PC) drug-eluting stents (DES) in patients with angina or acute coronary syndrome (ACS) undergoing percutaneous coronary intervention has received limited study.
Yusuke Watanabe MD,Satoru Mitomo MD,Toru Naganuma MD,Alaide Chieffo MD,Matteo Montorfano MD,Sunao Nakamura MD, PhD,Antonio Colombo MD
doi : 10.1002/ccd.29954
Volume 98, Issue 6 p. E814-E822
This study evaluated the 5-years outcomes of intracoronary imaging-guided proximal optimization technique (POT) for percutaneous coronary intervention (PCI) in patients with unprotected left main distal bifurcation lesions (ULMD).
Chih-Wei Chang MD,Subeer Kanwar Wadia MD,Ashish Rastogi MD,Curtiss Tyler Stinis MD
doi : 10.1002/ccd.29919
Volume 98, Issue 6 p. E823-E827
Delayed coronary obstruction is a rare but often fatal complication of transcatheter aortic valve replacement that can present within 24?hr after the transcatheter aortic valve replacement procedure. We present a case of a 77-year-old woman whose distal left main coronary artery bifurcation became obstructed by an embolized piece of native valve leaflet material 16?hours after the uncomplicated transfemoral implantation of an Edwards Sapien Ultra 23?mm aortic valve, which was successfully treated with the simultaneous kissing stent technique.
Christopher Herron DO,Thomas J. Forbes MD, FSCAI,Daisuke Kobayashi MD, MPH, FSCAI
doi : 10.1002/ccd.29928
Volume 98, Issue 6 p. E828-E831
Pulmonary artery tumor embolism is a rare phenomenon and its diagnosis is important because of a poor prognosis. We report a 20-year-old male with history of metastatic osteosarcoma who presented with acute pulmonary embolism. He was urgently taken to the catheterization laboratory and underwent transcatheter aspiration of pulmonary artery mass using an INARI Triever aspiration catheter. Pathology of the aspirated specimen lead to the diagnosis of pulmonary artery tumor embolism, not thrombus. This case highlights the diagnostic utility of transcatheter aspiration for the pulmonary artery tumor embolism.
Felix Mahfoud MD,Stefan Bertog MD,Lucas Lauder MD,Michael Böhm MD,Axel Schmid MD,Wojciech Wojakowski MD,Helen Parise ScD,Tim A. Fischell MD,David E. Kandzari MD,Atul Pathak MD,Alexandre Persu MD,Horst Sievert MD
doi : 10.1002/ccd.29936
Volume 98, Issue 6 p. E832-E838
The current analysis utilized core laboratory angiographic data from a prospective, single-arm, open-label, multi-center feasibility study to ascertain whether the location of alcohol infusion within main renal arteries during renal denervation (RDN) had an impact on the BP-lowering effect at 6 months.
Salik Nazir MD,Keerat Rai Ahuja MD,Robert W. Ariss BS,Mohamed Hassanein MD,Paul Schurmann MD,Srikanth Koneru MD,Hamid Afshar MD,Irakli Giorgberidze MD,George V. Moukarbel MD,Hani Jneid MD
doi : 10.1002/ccd.29711
Volume 98, Issue 6 p. E839-E846
Using a large nationally representative database, we aimed to examine risk factors for acute kidney injury (AKI) and its association with outcomes in patients undergoing percutaneous left atrial appendage closure (LAAC).
Federico De Marco MD, PhD,Matteo Casenghi MD,Pietro Spagnolo MD,Antonio Popolo Rubbio MD,Nedy Brambilla MD,Luca Testa MD, PhD,Francesco Bedogni MD
doi : 10.1002/ccd.29737
Volume 98, Issue 6 p. E847-E854
The aim of this proof-of-concept study was to investigate safety and efficacy of a CT-scan based patient-specific algorithm to maximize coronary clearance and secondarily to achieve anatomically correct commissural alignment with the Acurate Neo device.
Ramez Morcos MD MBA,Michael Megaly MD, MS,Anand Desai MD,Mohamed Alkhouli MD,Marwan Saad MD, PhD,Michael Luna MD,Santiago Garcia MD,Houman Khalili MD,Brijeshwar Maini MD
doi : 10.1002/ccd.29746
Volume 98, Issue 6 p. E855-E861
There is a paucity of literature on safety and efficacy of various transseptal puncture (TSP) needles.
Katia Orvin MD,Leor Perl MD,Uri Landes MD,Danny Dvir MD,John George Webb MD,Marie-Elisabeth Stelzmüller MD,Wilfried Wisser MD,Tamim Michael Nazif MD,Isaac George MD,Mizuki Miura MD, PhD,Maurizio Taramasso MD, PhD,Thomas Pilgrim MD, MSc,Monika Fürholz MD,Jan-Malte Sinning MD,Georg Nickenig MD,Chris Rumer MD,Giuseppe Tarantini MD,Giulia Masiero MD,Matjas Bunc MD,Peter Radsel MD PhD,Azeem Latib MD,Faraj Kargoli MD,Alfonso Ielasi MD,Massimo Medda MD,Luis Nombela-Franco MD, PhD,Hana Vaknin-Assa MD,Ran Kornowski MD
doi : 10.1002/ccd.29747
Volume 98, Issue 6 p. E862-E869
To evaluate the use and outcomes of percutaneous mechanical circulatory support (pMCS) utilized during transcatheter aortic valve implantation (TAVI) from high-volume centers.
Victor Razuk MD,Anton Camaj MD, MS,Davide Cao MD,Johny Nicolas MD,Christian Hengstenberg MD,Samantha Sartori PhD,Zhongjie Zhang MPH,David Power MD,Frans Beerkens MD,Mauro Chiarito MD,Nicolas Meneveau MD,Christophe Tron MD,Nicolas Dumonteil MD,Julian D. Widder MD,Markus Ferrari MD,Roberto Violini MD,Pieter R. Stella MD, PhD,Raban Jeger MD,Prodromos Anthopoulos MD,Roxana Mehran MD,George D. Dangas MD, PhD
doi : 10.1002/ccd.29753
Volume 98, Issue 6 p. E870-E880
To determine the prognostic impact of anemia in patients randomized to bivalirudin or unfractionated heparin (UFH) during transcatheter aortic valve replacement (TAVR).
Simon Schoechlin MD,Undine Schulz MD,Philip Ruile MD, PhD,Manuel Hein MD,Martin Eichenlaub MD,Nikolaus Jander MD, PhD,Franz-Josef Neumann MD, PhD,Christian Valina MD
doi : 10.1002/ccd.29781
Volume 98, Issue 6 p. E881-E888
Constant elevations of the serum concentration of cardiac troponin T (TnT) indicate a myocardial injury that may affect the long-term outcome of transcatheter aortic valve replacement (TAVR).
Francisco José Romeo MD,Juan Guido Chiabrando MD,Ignacio Miguel Seropian MD,Juan Valle Raleigh MD,Horacio Medina de Chazal MD,Cristian Maximiliano Garmendia MD,Maximiliano Smietniansky MD,Mariela Cal MD,Carla Romina Agatiello MD,Daniel Horacio Berrocal MD, PhD
doi : 10.1002/ccd.29799
Volume 98, Issue 6 p. E889-E896
Sarcopenia is a prevalent condition in elderly patients and has been associated with adverse outcomes following transcatheter aortic valve replacement (TAVR). The present study aimed to determine the predictive value of serum creatinine-cystatin C ratio, that is, “Sarcopenia Index” (SI) as a surrogate marker of sarcopenia, and investigate its association with clinical outcomes after TAVR.
Oliver Maier MD,Kerstin Piayda MD,Shazia Afzal MD,Amin Polzin MD,Ralf Westenfeld MD,Christian Jung MD,Tobias Zeus MD,Gerald Antoch MD,Malte Kelm MD,Verena Veulemans MD
doi : 10.1002/ccd.29805
Volume 98, Issue 6 p. E897-E907
This meta-analysis sought to assess predictors of permanent pacemaker implantation (PPI) after transcatheter aortic valve replacement (TAVR) with focus on preprocedural multi-slice computed tomography (MSCT) derived data.
Johny Nicolas MD,Paul Guedeney MD,Bimmer E. Claessen MD, PhD,Julinda Mehilli MD,Anna Sonia Petronio MD,Samantha Sartori PhD,Thierry Lefèvre MD,Patrizia Presbitero MD,Piera Capranzano MD,Alessandro Iadanza MD,Davide Cao MD,Mauro Chiarito MD,Ridhima Goel MD,Anastasios Roumeliotis MD,Rishi Chandiramani MD,Siyan Chen BS,Gennaro Sardella MD,Nicolas M. Van Mieghem MD, PhD,Sabato Sorrentino MD, PhD,Emanuele Meliga MD, PhD,Didier Tchétché MD,Nicolas Dumonteil MD,Chiara Fraccaro MD, PhD,Daniela Trabattoni MD,Ghada W. Mikhail MD, FRCP,Maria-Cruz Ferrer-Gracia MD,Christoph Naber MD,Peter C. Kievit MD,Usman Baber MD, MS,Samin K. Sharma MD,Marie-Claude Morice MD,George D. Dangas MD, PhD,Jaya Chandrasekhar MBBS, MS,Alaide Chieffo MD,Roxana Mehran MD
doi : 10.1002/ccd.29807
Volume 98, Issue 6 p. E908-E917
To describe the incidence, predictors, and clinical impact of permanent pacemaker insertion (PPI) following transcatheter aortic valve replacement (TAVR) in women.
Moses Mathur MD, MSc,Chad J. Zack MD, MS,Ashley Heatley CRNP,Denise Rhodes CRNP,Kentaro Yamane MD,Ian C. Gilchrist MD,Mark Kozak MD
doi : 10.1002/ccd.29832
Volume 98, Issue 6 p. E918-E921
Contemporary direct (“fully percutaneous”) transaxillary (TAx) large-bore arterial access technique advocates for a 0.018” wire to be passed from femoral arterial access to axillary artery to serve percutaneous bailout options. However, in certain patients, avoiding femoral arterial access entirely may be desired. We describe the merits of a “fully upper extremity” (FUE) bailout approach, as a refinement to previously described direct TAx technique.
Ulrich Fischer-Rasokat MD, PhD,Matthias Renker MD,Christoph Liebetrau MD, PhD,Maren Weferling MD,Andreas Rolf MD, PhD,Mirko Doss MD, PhD,Christian W. Hamm MD, PhD,Won-Keun Kim MD
doi : 10.1002/ccd.29840
Volume 98, Issue 6 p. E922-E931
Blunted left ventricular hemodynamics reflected by a low stroke volume index (SVI) ?35?mL/m2 body surface area (low flow [LF]) in patients with severe aortic stenosis (AS) are associated with worse outcomes even after correction of afterload by transcatheter aortic valve implantation (TAVI). These patients can have a low or high transvalvular mean pressure gradient (MPG). We investigated the impact of the pre-interventional MPG on outcomes after TAVI.
Didem Oguz MD,Ratnasari Padang MBBS, PhD,Sorin V. Pislaru MD, PhD,Vuyisile T. Nkomo MD, MPH,Sunil V. Mankad MD,Mohamad Alkhouli MD,Mayra Guerrero MD,Guy S. Reeder MD,Mackram F. Eleid MD,Charanjit S. Rihal MD,Jeremy J. Thaden MD
doi : 10.1002/ccd.29867
Volume 98, Issue 6 p. E932-E937
The predictors and clinical significance of increased Doppler-derived mean diastolic gradient (MG) following transcatheter edge-to-edge mitral valve repair (MVTEER) remain controversial.
Jesse Goitia MD,Derek Q. Phan MD,Ming-Sum Lee MD, PhD,Naing Moore MD,Prakash Mansukhani MD,Vicken Aharonian MD,Somjot S. Brar MD, MPH,Ray Zadegan MD
doi : 10.1002/ccd.29872
Volume 98, Issue 6 p. E938-E946
Neighborhoods have a powerful impact on health. Prior investigations into disparities associated with transcatheter aortic valve replacement (TAVR) have focused on race and access to the procedure. We sought to investigate the role of neighborhood disadvantage on mortality post-TAVR.
Dawid L. Staudacher MD,Katrin Braxmeier MS,Peter Stachon MD,Ingo Hilgendorf MD,Christopher Schlett MD,Manfred Zehender MD,Constantin von zur Mühlen MD,Christoph Bode MD,Timo Heidt MD
doi : 10.1002/ccd.29885
Volume 98, Issue 6 p. E947-E953
We aimed to identify risk factors for major transcatheter aortic valve intervention (TAVI) access site complications based on detailed analysis of the preprocedural computed tomography angiogram (CTA).
Raviteja R. Guddeti MD,Venkata S. Pajjuru MD,Ryan W. Walters PhD,Santiago A. Garcia MD,Venkata M. Alla MD
doi : 10.1002/ccd.29887
Volume 98, Issue 6 p. E954-E962
Patients undergoing transcatheter edge-to-edge mitral valve repair (TEER) carry a high risk of rehospitalization due to disease, procedure, patient, hospital, and system related factors.
Kerstin Piayda MD,Iris Grunwald MD,Kolja Sievert MD,Stefan Bertog MD,Horst Sievert MD
doi : 10.1002/ccd.29820
Volume 98, Issue 6 p. E963-E967
Acute ischemic stroke is a feared complication during cardiovascular procedures associated with high morbidity and mortality if not immediately recognized and treated. We conducted a review of cases at our center where patients experienced an acute, procedure-related ischemic stroke and underwent immediate endovascular stroke treatment by the interventional cardiologists trained in acute endovascular stroke intervention. Baseline demographics, procedural and follow-up data were collected. Three patients were identified in whom the percutaneous procedure (peripheral arterial intervention, transapical NeoChord [NeoChord Inc, Minnesota, USA] implantation and transcatheter aortic valve implantation, respectively) was complicated by an acute embolic ischemic stroke. In all cases, cerebral vessel re-canalization was technically successful with thrombolysis in cerebral infarction (TICI) IIB/III flow. Follow-up computed tomography scans showed no infarct demarcation, oedema or intracranial hemorrhage. One patient survived with no neurological symptoms at 6-month follow-up whereas the two other patients died of unrelated intensive care complications and decompensated heart failure. We conclude that endovascular stroke treatment during cardiovascular interventions can be performed by interventional cardiologists with appropriate training. It offers the unique opportunity to treat cerebral embolization in a time-efficient manner, potentially improving morbidity and mortality of affected patients.
Carlo Briguori MD, PhD,Mario Scarpelli MD
doi : 10.1002/ccd.29915
Volume 98, Issue 6 p. E968-E970
Crossover balloon occlusion technique (CBOT) has been proposed to ensure adequate closure of the arterial access used for transcatheter aortic valve replacement (TAVR). However, the CBOT performed through the contralateral femoral artery could be challenging in cases of excessively tortuous and calcified vessels or in the presence of narrow iliac carina angles. We describe a novel technique to facilitate the advancement the peripheral balloon through the contralateral femoral artery up to the target iliofemoral system in order to facilitate access site hemostasis. The present “locking and drugging” technique takes advantages from two mechanical aspects: (a) the locking of the 0.018? wire between the vessel wall and the TAVR delivery system or the dedicated sheath, which facilitate the crossover of the balloon in the contralateral iliofemoral system, preventing its prolapse into the aorta at the carina level and (b) the dragging of the balloon advanced into the contralateral iliofemoral system during the retrieve of the TAVR delivery system or the dedicated sheath.
Francesco Maisano MD,Giulio Russo MD, PhD,Ana Paula Tagliari MD, MSc,Mara Gavazzoni MD,Maurizio Taramasso MD, PhD
doi : 10.1002/ccd.29950
Volume 98, Issue 6 p. E971-E976
Optimal transseptal puncture (TSP) position on the interatrial septum as well as proper catheter direction and maneuverability in the left atrium (LA) are key elements for successful mitral valve (MV) interventions. TSP is usually performed from the right femoral vein being more comfortable for the operator and easier to reach the fossa ovalis. In the cases reported, TSP was performed from left femoral vein (LFV) to improve delivery system maneuverability and trajectory inside the LA in the context of MV repair with MitraClip. According to this early experience, LFV approach might be considered as first choice or as an alternative solution in patients in whom a higher position of the delivery system relative to the mitral annulus is needed.
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