Filippo Crea
doi : 10.1093/eurheartj/ehab746
European Heart Journal, Volume 42, Issue 41, 1 November 2021, Pages 4197–4201
Mattia Lunardi, Darren Mylotte, William Wijns, Yoshinobu Onuma, Osama Soliman, Patrick W Serruys, Faisal Sharif
doi : 10.1093/eurheartj/ehab409
European Heart Journal, Volume 42, Issue 41, 1 November 2021, Pages 4202–4205
Ivan Oransky, Stephen E Fremes, Paul Kurlansky, Mario Gaudino
doi : 10.1093/eurheartj/ehab398
European Heart Journal, Volume 42, Issue 41, 1 November 2021, Pages 4205–4206
Alec Vahanian, Fabien Praz, Milan Milojevic, Friedhelm Beyersdorf
doi : 10.1093/eurheartj/ehab626
European Heart Journal, Volume 42, Issue 41, 1 November 2021, Pages 4207–4208
Yaling Han
doi : 10.1093/eurheartj/ehab437
European Heart Journal, Volume 42, Issue 41, 1 November 2021, Pages 4209–4211
Francesco Paneni, Carlo Patrono
doi : 10.1093/eurheartj/ehab636
European Heart Journal, Volume 42, Issue 41, 1 November 2021, Pages 4211–4212
Philip Moons, Ewa-Lena Bratt, Julie De Backer, Eva Goossens, Tim Hornung, Oktay Tutarel, Liesl Zühlke, John Jairo Araujo, Edward Callus, Harald Gabriel, Nauman Shahid, Karen Sliwa, Amy Verstappen, Hsiao-Ling Yang, Corina Thomet
doi : 10.1093/eurheartj/ehab388
European Heart Journal, Volume 42, Issue 41, 1 November 2021, Pages 4213–4223
The vast majority of children with congenital heart disease (CHD) in high-income countries survive into adulthood. Further, paediatric cardiac services have expanded in middle-income countries. Both evolutions have resulted in an increasing number of CHD survivors. Expert care across the life span is necessitated. In adolescence, patients transition from being a dependent child to an independent adult. They are also advised to transfer from paediatrics to adult care. There is no universal consensus regarding how transitional care should be provided and how the transfer should be organized. This is even more challenging in countries with low resources. This consensus document describes issues and practices of transition and transfer of adolescents with CHD, accounting for different possibilities in high-, middle-, and low-income countries. Transitional care ought to be provided to all adolescents with CHD, taking into consideration the available resources. When reaching adulthood, patients ought to be transferred to adult care facilities/providers capable of managing their needs, and systems have to be in place to make sure that continuity of high-quality care is ensured after leaving paediatric cardiology.
Gabriele Egidy Assenza, Konstantinos Dimopoulos, Werner Budts, Andrea Donti, Katherine E Economy, Gaetano Domenico Gargiulo, Michael Gatzoulis, Michael Job Landzberg, Anne Marie Valente, Jolien Roos-Hesselink
doi : 10.1093/eurheartj/ehab546
European Heart Journal, Volume 42, Issue 41, 1 November 2021, Pages 4224–4240
The growing population of women with heart disease of reproductive age has been associated with an increasing number of high-risk pregnancies. Pregnant women with heart disease are a very heterogeneous population, with different risks for maternal cardiovascular, obstetric, and foetal complications. Adverse cardiovascular events during pregnancy pose significant clinical challenges, with uncertainties regarding diagnostic and therapeutic approaches potentially compromising maternal and foetal health. This review summarizes best practice for the treatment of common cardiovascular complications during pregnancy, based on expert opinion, current guidelines, and available evidence. Topics covered include heart failure (HF), arrhythmias, coronary artery disease, aortic and thromboembolic events, and the management of mechanical heart valves during pregnancy. Cardiovascular pathology is the leading cause of non-obstetric morbidity and mortality during pregnancy in developed countries. For women with pre-existing cardiac conditions, preconception counselling and structured follow-up during pregnancy are important measures for reducing the risk of acute cardiovascular complications during gestation and at the time of delivery. However, many women do not receive pre-pregnancy counselling often due to gaps in what should be lifelong care, and physicians are increasingly encountering pregnant women who present acutely with cardiac complications, including HF, arrhythmias, aortic events, coronary syndromes, and bleeding or thrombotic events. This review provides a summary of recommendations on the management of acute cardiovascular complication during pregnancy, based on available literature and expert opinion. This article covers the diagnosis, risk stratification, and therapy and is organized according to the clinical presentation and the type of complication, providing a reference for the practicing cardiologist, obstetrician, and acute medicine specialist, while highlighting areas of need and potential future research.
Gerhard-Paul Diller, Stefan Orwat, Astrid Elisabeth Lammers, Robert M Radke, Fernando De-Torres-Alba, Renate Schmidt, Ursula Marschall, Ulrike M Bauer, Dominic Enders, Leo Bronstein, Gerrit Kaleschke, Helmut Baumgartner
doi : 10.1093/eurheartj/ehab422
European Heart Journal, Volume 42, Issue 41, 1 November 2021, Pages 4241–4248
The aim of this study was to provide population-based data on the healthcare provision for adults with congenital heart disease (ACHD) and the impact of cardiology care on morbidity and mortality in this vulnerable population.
Abigail D Khan, Anne Marie Valente
doi : 10.1093/eurheartj/ehab281
European Heart Journal, Volume 42, Issue 41, 1 November 2021, Pages 4249–4251
Astrid Elisabeth Lammers, Gerhard-Paul Diller, Rieke Lober, Mareike Möllers, Renate Schmidt, Robert M Radke, Fernando De-Torres-Alba, Gerrit Kaleschke, Ursula Marschall, Ulrike M Bauer, Joachim Gerß, Dominic Enders, Helmut Baumgartner
doi : 10.1093/eurheartj/ehab571
European Heart Journal, Volume 42, Issue 41, 1 November 2021, Pages 4252–4260
The aim of this study was to provide population-based data on maternal and neonatal complications and outcome in the pregnancies of women with congenital heart disease (CHD).
Karishma P Ramlakhan, Jolien W Roos-Hesselink
doi : 10.1093/eurheartj/ehab692
European Heart Journal, Volume 42, Issue 41, 1 November 2021, Pages 4261–4263
Siyeon Rhee, David T Paik, Johnson Y Yang, Danielle Nagelberg, Ian Williams, Lei Tian, Robert Roth, Mark Chandy, Jiyeon Ban, Nadjet Belbachir, Seokho Kim, Hao Zhang, Ragini Phansalkar, Ka Man Wong, Devin A King, Caroline Valdez, Virginia D Winn, Ashby J Morrison, Joseph C Wu, Kristy Red-Horse
doi : 10.1093/eurheartj/ehab298
European Heart Journal, Volume 42, Issue 41, 1 November 2021, Pages 4264–4276
Non-compaction cardiomyopathy is a devastating genetic disease caused by insufficient consolidation of ventricular wall muscle that can result in inadequate cardiac performance. Despite being the third most common cardiomyopathy, the mechanisms underlying the disease, including the cell types involved, are poorly understood. We have previously shown that endothelial cell-specific deletion of the chromatin remodeller gene Ino80 results in defective coronary vessel development that leads to ventricular non-compaction in embryonic mouse hearts. We aimed to identify candidate angiocrines expressed by endocardial and endothelial cells (ECs) in wildtype and LVNC conditions in Tie2Cre;Ino80fl/fltransgenic embryonic mouse hearts, and test the effect of these candidates on cardiomyocyte proliferation and maturation.
Julian U G Wagner, Stefanie Dimmeler
doi : 10.1093/eurheartj/ehab304
European Heart Journal, Volume 42, Issue 41, 1 November 2021, Pages 4277–4279
Karolina Agnieszka Wartolowska, Alastair John Stewart Webb
doi : 10.1093/eurheartj/ehab566
European Heart Journal, Volume 42, Issue 41, 1 November 2021, Pages 4280–4281
Franz H Messerli, Chirag Bavishi, Adrian W Messerli, George C M Siontis
doi : 10.1093/eurheartj/ehab567
European Heart Journal, Volume 42, Issue 41, 1 November 2021, Page 4282
Yusuke Akazawa, Takashi Higaki, Tomozo Moritani, Osamu Yamaguchi
doi : 10.1093/eurheartj/ehaa915
European Heart Journal, Volume 42, Issue 41, 1 November 2021, Page 4283
Giulia Pasqualin, Francesco Sturla, Angelo Fabio D’Aiello, Massimo Chessa
doi : 10.1093/eurheartj/ehaa961
European Heart Journal, Volume 42, Issue 41, 1 November 2021, Page 4284
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