دسترسی یکساله به بیش از ۵۰۰ ژورنال روز جهان موجود در سامانه
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COVID-19 skin lesions are rarely positive at RT-PCR test: the macrophage activation with vascular impact and SARS-CoV-2-induced cytokine storm
Marius-Anton Ionescu MD, PhD
doi : 10.1111/ijd.15749
Volume 61, Issue 1 p. 3-6
Several skin manifestations have been reported since the start of the COVID-19 pandemic: chilblains-like, livedoid lesions, urticaria-like, pseudo-Kawasaki disease, and others. Histopathologic images of these lesions most often show aspects of endothelitis, images similar to autoimmune vasculitis. Cutaneous lesions are often negative at RT-PCR for SARS-CoV-2 virus.
Dermoscopy of acquired pigmentary disorders: a comprehensive review
Loren Krueger MD,Autumn Saizan BS,Jennifer A. Stein MD, PhD,Nada Elbuluk MD, MSc
doi : 10.1111/ijd.15741
Volume 61, Issue 1 p. 7-19
Dermoscopy has traditionally been used for the diagnosis of neoplasms and more recently in the evaluation of inflammatory conditions. Recent observational studies have suggested a role for dermoscopy in identifying and differentiating acquired pigmentary disorders. This comprehensive review will summarize the growing literature on the use of dermoscopy for pigmentary disorders. A literature review was performed on PubMed dating from inception to October 2020. The following pigmentary disorders were included in this study: melasma, solar lentigines, poikiloderma of Civatte, exogenous ochronosis, lichen planus pigmentosus, erythromelanosis follicularis faciei et colli, pigmented contact dermatitis, Riehl’s melanosis, postinflammatory hyperpigmentation, erythema dyschromicum perstans, ashy dermatosis, confluent and reticulated papillomatosis, acanthosis nigricans, pityriasis versicolor, tinea versicolor, idiopathic guttate hypomelanosis, and vitiligo. Search terms used included each pigmentary disorder along with the terms “dermoscopy” or “dermatoscopy.” Relevant case reports and case series were included. Many pigmentary disorders have unique and distinguishable features on dermoscopy. Given that these disorders can be clinically challenging for clinicians and emotionally distressing for patients, dermoscopy provides an additional, useful tool in the evaluation and assessment process.
COVID-19-related oral mucosa lesions among confirmed SARS-CoV-2 patients: a systematic review
Gizem S. Erba?,Aysenur Botsali MD,Nihan Erden MD,Canan Ar? MD,Banu Ta?k?n MD,Sibel Alper MD,Secil Vural MD
doi : 10.1111/ijd.15889
Volume 61, Issue 1 p. 20-32
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the virus responsible for coronavirus disease 2019 (COVID-19), which manifests as a flu-like respiratory infection affecting multiple organ systems, including the gastrointestinal system, central nervous system, cardiovascular system, skin, and mucosa. In this review, we investigated the literature on specific manifestations of COVID-19 in the oral mucosa. An online literature search in PubMed, Scopus, Google Scholar, and Medline was conducted to retrieve relevant studies on confirmed COVID-19 patients with oral mucosa findings published between December 31, 2019, and April 07, 2021. After an independent review by two authors, 39 articles considering 59 laboratory-confirmed cases of SARS-CoV-2 infection were included in the final analysis. The most common finding, reported in 29 patients (43.9%), was Kawasaki-like syndrome. In addition, oral ulcers including aphthous, hemorrhagic, and necrotic ulcers were reported in 24 patients (36.3%). Other lesions reported included pustules, macules, bullae, maculopapular enanthema, and erythema multiforme-like lesions. Concomitant skin lesions were present in 60.6% of patients. Fever was reported in 86.2% of patients. Forty-eight patients (76.1%) were hospitalized. Loss of taste and smell was present in 30.8% of the patients. A comprehensive understanding of the dermatologic manifestations of COVID-19 can improve and facilitate patient management and referrals.
Could it be gluten? Additional skin conditions associated with celiac disease
Natasha Klemm MD,Melinda J. Gooderham MSc, MD,Kim Papp MD, PhD
doi : 10.1111/ijd.15750
Volume 61, Issue 1 p. 33-38
Celiac disease is a multifactorial, inflammatory disorder initiated and sustained by the ingestion of gluten. Occurring across a broad population, the intestinal and extraintestinal manifestations of celiac disease are variable in severity and may be nonspecific in presentation. Given that environmental, genetic, and immune factors involved in the pathogenesis of celiac disease that the digestive tract and skin share many characteristics, and with a prevalence of 0.5–1% in most populations, it is reasonable to consider varying presentations of skin conditions that are linked with celiac disease. The association between celiac disease and skin conditions has been discussed earlier, but new studies have emerged suggesting cutaneous involvement in addition to dermatitis herpetiformis. We review the current literature identifying the relationship and potential mechanisms between celiac disease and various skin conditions.
Cutaneous manifestations in children with SARS-CoV-2 infection and/or COVID-19: what do we know after 10 months under this pandemic?
Hongxin Li MD,Yong Zhao PhD,Lin Zhou
doi : 10.1111/ijd.15882
Volume 61, Issue 1 p. 39-45
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has become a global crisis. However, cutaneous manifestations in children with SARS-CoV-2 infection have received little attention.
An erosive plaque of the right nipple
Anissa Zaouak MD,Hafsa Touati MD,Azima Ben Tanfous MD,Fatma Khanchel MD,Ehsen Ben Brahim MD,Olfa Khayat MD,Samy Fenniche MD,Houda Hammami MD
doi : 10.1111/ijd.15745
Volume 61, Issue 1 p. 46-47
Dermatology inpatient consultations in a tertiary hospital – a retrospective analysis
Joseph Joseph MD, BPharm,Kelvin Truong MD, BPharm,Annika Smith MBBS Hons 1, MPHTM, FRACP, FACD,Pablo Fernandez-Penas MD, PhD, FACD
doi : 10.1111/ijd.15724
Volume 61, Issue 1 p. 48-53
Dermatology consultation has been shown to have a significant beneficial impact on admitted hospital patients with concurrent or newly diagnosed skin conditions. This study aimed to determine the change in diagnosis and management after dermatology consultation in a tertiary Australian referral hospital.
Anti-aging effect of an oral disintegrating collagen film: a prospective, single-arm study
Young In Lee MD, PhD,Sang Gyu Lee MS,Eunbin Kim BS,Inhee Jung MS,Jangmi Suk MS,Jihee Kim MD, PhD,Ju Hee Lee MD, PhD
doi : 10.1111/ijd.15675
Volume 61, Issue 1 p. 54-61
As the average life expectancy increases, skin aging and wrinkles due to photoaging have gained attention. Collagen is closely involved in the process of skin aging. Among the potential methods of drug delivery to the skin, oral disintegrating films show promise for their ability to bypass the loss of active components that is typical of drug absorption via oral administration. This study was conducted to investigate the effect of an oral disintegrating collagen film on skin aging.
Stewart-Treves syndrome and other cutaneous malignancies in the context of chronic lymphedema: a systematic review
Patrick J. Kim BHSc,Asfandyar Mufti MD,Muskaan Sachdeva BHSc,Yuliya Lytvyn PhD,Dorsa Zabihi-Pour BSc,Hiba Zaaroura MD,Jensen Yeung MD, FRCPC
doi : 10.1111/ijd.15736
Volume 61, Issue 1 p. 62-70
Angiosarcoma developing in chronically lymphedematous tissue, or Stewart-Treves syndrome (STS), is a rare and lethal complication of lymphedema. This systematic review summarizes characteristics and outcomes of STS and other cutaneous malignancies arising in chronic lymphedema.
Is it possible to repigment iatrogenic and traumatic hypochromic lesions? A case series using the MMP® drug delivery technique with 5-fluorouracil and bleomycin
Samir Arbache MD,Samia T. Arbache MD,Sergio H. Hirata MD, PhD
doi : 10.1111/ijd.15725
Volume 61, Issue 1 p. 71-83
We present the results of 11 patients with hypochromic lesions treated with antifibrotic agents delivered through the MMP® technique.
Hepatitis B and C among patients with hidradenitis suppurativa: a population-based study
Jeffrey M. Cohen MD,Khalaf Kridin MD, PhD,Lourdes M. Perez-Chada MD, MMSc,Joseph F. Merola MD, MMSc,Arnon D. Cohen MD, PhD, MPH
doi : 10.1111/ijd.15578
Volume 61, Issue 1 p. 84-88
Hidradenitis suppurativa (HS) is a chronic inflammatory condition related to multiple systemic diseases and infections.
Cutaneous leishmaniasis: new oral therapeutic approaches under development
Myla Lôbo de Souza MSc,Widson Michael dos Santos MSc,André Luiz Moreira Domingues de Sousa MSc,Leslie Raphael de Moura Ferraz PhD,Lucas Amadeu Gonzaga da Costa BSc,Emerson Oliveira Silva MSc,Pedro José Rolim Neto PhD
doi : 10.1111/ijd.15902
Volume 61, Issue 1 p. 89-98
The World Health Organization (WHO) classifies leishmaniasis as a disease for which the development of new treatments is a priority. Available drugs are not fully effective in all cases; they have parenteral administration and exhibit serious and common adverse effects. The only oral drug available (miltefosine) has shown resistance, is expensive, and is not available in many endemic countries. Thus, the development of an oral medicine may solve many of these issues. Based on that, this review aimed to investigate which therapeutic alternatives have been studied for the development of oral drugs for the treatment of cutaneous leishmaniasis. A literature search for keywords “leishmania and oral” was performed in PubMed and ScienceDirect, considering articles published in the last 5?years. The articles were selected based on the objective of the review. The main problem in the current treatment of leishmaniasis is the administration of injectables, since it requires patients to travel to health centers, hospitalization, and professional administration, conditions that are not adapted to the socioeconomic reality of patients. Therefore, many research studies have evaluated oral alternatives for the treatment of cutaneous leishmaniasis. The main tested approaches were obtaining new molecules, repositioning drugs, and new formulations of old drugs. The prospects are encouraging but still require more in?vivo bioavailability and clinical trials.
Developing an LGBT curriculum and evaluating its impact on Dermatology Residents
Nathan Vengalil MD,Daniel Shumer MD, MPH,Frank Wang MD
doi : 10.1111/ijd.15842
Volume 61, Issue 1 p. 99-102
Successful treatment for the different and rare cause of facial lymphedema: Morbus Morbihan disease
P?nar Borman MD,Ay?egül Yaman MD
doi : 10.1111/ijd.15643
Volume 61, Issue 1 p. 103-105
Chromobacterium violaceum sepsis with extensive vesiculobullous eruptions
Gopikrishnan Anjaneyan MD, DNB,Praveena Bhaskaran MD, DCH, DNB,Saranya Vijay MD,Nandita Shashindran MD,Chandrashekhara Jayakumar MD, DCH, FIAP
doi : 10.1111/ijd.15663
Volume 61, Issue 1 p. 106-108
Auricular pseudocysts: a systematic review of the literature
Anthony Ballan MD,Serge Zogheib MD,Cyril Hanna MD,Bechara Daou MD,Marwan Nasr MD,Samer Jabbour MD
doi : 10.1111/ijd.15816
Volume 61, Issue 1 p. 109-117
Auricular pseudocysts are benign fluid accumulations of the ear of uncertain etiology. Little is known about the optimal modality to successfully treat these lesions. No systematic review addressing auricular pseudocysts have been published to date.
Hedgehog inhibitors with and without adjunctive therapy in treatment of locally advanced basal cell carcinoma
Akash D. Patel BS,Surya Ravichandran MD,Meenal Kheterpal MD, MMCi
doi : 10.1111/ijd.15836
Volume 61, Issue 1 p. 118-124
Hedgehog inhibitor therapy (HHIT) is considered first-line treatment for locally advanced, unresectable basal cell carcinoma (laBCC). HHIT often results in a partial response, which requires adjunctive therapy (AT) post HHIT. We present real-world data for laBCCs undergoing HHIT?±?AT.
A case of HIV-associated generalized syphilitic alopecia mimicking alopecia universalis
Jacob S. Sons MBChB (UKZN),Antoinette Chateau BSc, MBChB, DCH, FC Derm (SA), MMedSci,Ncoza C. Dlova MBCHB, FC Derm (SA), PhD
doi : 10.1111/ijd.15721
Volume 61, Issue 1 p. e1-e2
An emerging threat of recalcitrant dermatophytosis in Sri Lanka - are we ready to tackle?
Nayani P. Madarasingha MD,Surammika Eriyagama MD
doi : 10.1111/ijd.15935
Volume 61, Issue 1 p. e2-e3
Disseminated ulcerated nodules, unilateral tonsillitis, and malaise
Nicola Hermann MD,Andrea Binkert MD,Isabel Kolm MD
doi : 10.1111/ijd.15904
Volume 61, Issue 1 p. e4-e5
Re-emergence of lymphogranuloma venereum in Vietnam
Ngo Binh Trinh MD,Khanh Duy Doan MD
doi : 10.1111/ijd.15731
Volume 61, Issue 1 p. e5-e6
A rare cause of cutaneous nodule: cutaneous myxoid fibroblastoma
Prajwal Pandey MD,Muna Bista MD,Suman Pakhrin MD,Samir Shrestha MD
doi : 10.1111/ijd.15843
Volume 61, Issue 1 p. e6-e8
A case report of a man with multiple subcutaneous nodules and joint pain
Nada Bennouna MD,Fatima-Zahra Elfatoïki MD,Zakaria El Ouali MD,Kawtar Nassar MD,Fouzia Hali MD,Hayat Dahbi Skali MD,Saadia Janani MD,Soumiya Chiheb MD
doi : 10.1111/ijd.15872
Volume 61, Issue 1 p. e8-e10
Two new cases of testicular choriocarcinoma with cutaneous metastases
Thelma L. Orizaga-y-Quiroga MD,Sonia S. Ocampo-Garza MD,Valeria Olvera-Rodríguez MD,Maira E. Herz-Ruelas MD,Minerva Gómez-Flores MD,Jorge Ocampo-Candiani MD
doi : 10.1111/ijd.15666
Volume 61, Issue 1 p. e10-e13
The need to prevent a future where dermatologists are only left to treat acne
Kerasia-Maria Plachouri MD, PhD,Francesk Mulita MD,Evaggelia Kalloniati MD,Sophia Georgiou MD, PhD
doi : 10.1111/ijd.15920
Volume 61, Issue 1 p. e13-e14
Pustular eruption after biosimilar rituximab infusion: report of acute generalized exanthematous pustulosis in two patients with pemphigus
Maryam Daneshpazhooh MD,Soheil Tavakolpour PhD,Ali Salehi Farid PharmD,Mehrnoosh Ebadi MD,Ali Nili MD,Mohammad Rashidian PhD,Hamidreza Mahmoudi MD
doi : 10.1111/ijd.15706
Volume 61, Issue 1 p. e14-e17
Nocardiosis mycetoma in an immunocompetent patient
Marie Guicheney,Olivia Peuchant MD, PhD,Vivien Guillotin PhD,Marie Beylot-Barry MD, PhD,Pierre Duffau MD, PhD
doi : 10.1111/ijd.15719
Volume 61, Issue 1 p. e17-e19
Excellent improvement of inflammatory acne vulgaris with monochromatic excimer light in a vitiligo patient
Ahmad Kamel Seddeik Abdel-Hameed MD,Ahmed Elsaeed Elsaadany MSc
doi : 10.1111/ijd.15906
Volume 61, Issue 1 p. e19-e20
A rare case of alopecia areata incognita
Vladimir Pinegin MD, PhD,Natalia Teplyuk MD, PhD,Anfisa Lepekhova MD, PhD
doi : 10.1111/ijd.15780
Volume 61, Issue 1 p. e20-e22
Association between smoking and alopecia areata: a systematic review and meta-analysis
Israel Khanimov MD
doi : 10.1111/ijd.15898
Volume 61, Issue 1 p. e22-e24
Network meta-analysis on the efficacy and safety of upadacitinib in adolescents and adults with moderate-to-severe atopic dermatitis
Mei Qiu MS,Xue-Yan Duan BS,Dao-Gen Yin MS
doi : 10.1111/ijd.15850
Volume 61, Issue 1 p. e24-e26
Therapy-refractory folliculitis decalvans treated with certolizumab pegol
Matthias Hoy MD,Markus Böhm MD
doi : 10.1111/ijd.15914
Volume 61, Issue 1 p. e26-e28
A patch of nonscarring alopecia on the vertex of a 16-year-old male: a case report and a review of the literature
Reine Merhy MD,Anne-Sophie Sarkis MD,Lea El Khoury MD,Samer Ghosn MD,Farid Stephan MD
doi : 10.1111/ijd.15616
Volume 61, Issue 1 p. e28-e29
Subcutaneous fat necrosis in a 14-day-old neonate presenting with multiple ulcers
Maynie Bambi Lugasan MD,Jennifer Aileen Tangtatco MD, FPDS, CWSP,Karla Phoebe Castaños MD, FPDS,Andrea Isabel Contreras MD
doi : 10.1111/ijd.15800
Volume 61, Issue 1 p. e29-e31
Multiple translucent papules on both eyebrows – the presenting sign of B-cell chronic lymphocytic leukemia
Catarina Correia MD,Sónia Fernandes MD,Daniela Alves MD,Paulo Filipe MD, PhD
doi : 10.1111/ijd.15682
Volume 61, Issue 1 p. e31-e33
Smoking and the risk of basal cell carcinoma: a systematic review and meta-analysis
Po-Chien Wu MD,I-Hsin Huang MD,Che-Wei Liu MD,Yu-Chen Huang MD
doi : 10.1111/ijd.15607
Volume 61, Issue 1 p. e33-e37
Nilotinib-induced lichen planopilaris
Ines Lahouel MD,Nesrine Ben Salah MD,Jacem Rouatbi MD,Sarra Boukhriss MD,Nouha Abdejlil MD,Monia Youssef PhD,Hichem Belhadjali PhD,Adnene Laatiri PhD,Jameledin Zili PhD
doi : 10.1111/ijd.15647
Volume 61, Issue 1 p. e37-e38
An unusual case of progressive nodular histiocytosis
Manrup K. Hunjan MBChB,Monica C. Anyasodor MBBS,Yelin L Hock MBBS,Anisha Mehta MBBS
doi : 10.1111/ijd.15886
Volume 61, Issue 1 p. e38-e40
A retrospective study of cellulitis outcomes in Ohio hospitals with or without access to dermatology residency programs
Nathalie Ly BS,Michael Goldenberg BS,Abraham M. Korman MD,Natalie Spaccarelli MD,Henry Wang MD,Catherine Chung MD,Benjamin H. Kaffenberger MD
doi : 10.1111/ijd.15611
Volume 61, Issue 1 p. e40-e42
