Saritha Krishna, PhD, Sofia Kakaizada, BS, Nyle Almeida, BS, David Brang, PhD, Shawn Hervey-Jumper, MD
doi : 10.1093/neuros/nyaa456
Neurosurgery, Volume 89, Issue 4, October 2021, Pages 539–548
Gliomas exist within the framework of complex neuronal circuitry in which network dynamics influence both tumor biology and cognition. The generalized impairment of cognition or loss of language function is a common occurrence for glioma patients. The interface between intrinsic brain tumors such as gliomas and functional cognitive networks are poorly understood. The ability to communicate effectively is critically important for receiving oncological therapies and maintaining a high quality of life. Although the propensity of gliomas to infiltrate cortical and subcortical structures and disrupt key anatomic language pathways is well documented, there is new evidence offering insight into the network and cellular mechanisms underpinning glioma-related aphasia and aphasia recovery. In this review, we will outline the current understanding of the mechanisms of cognitive dysfunction and recovery, using aphasia as an illustrative model.
Heyu Ding, MD, Pengfei Zhao, MD, Han Lv, MD, Xiaoshuai Li, MM, Xiaoyu Qiu, MM, Rong Zeng, MD, Guopeng Wang, MD, Zhenghan Yang, MD, Shusheng Gong, MD, Long Jin, MD, Zhenchang Wang, MD
doi : 10.1093/neuros/nyab222
Neurosurgery, Volume 89, Issue 4, October 2021, Pages 549–556
The relationship between trans-stenotic blood flow velocity differences and the cerebral venous pressure gradient (CVPG) in transverse sinus (TS) stenosis (TSS) has not been studied.
Yoshifumi Mizobuchi, MD, PhD, Shinji Nagahiro, MD, PhD, Akinori Kondo, MD, PhD, Kazunori Arita, MD, PhD, Isao Date, MD, PhD, Yukihiko Fujii, MD, PhD, Takamitsu Fujimaki, MD, PhD, Ryosuke Hanaya, MD, PhD, Mitsuhiro Hasegawa, MD, PhD, Toru Hatayama, MD, PhD, Tooru Inoue, MD, PhD, Hidetoshi Kasuya, MD, PhD, Masahito Kobayashi, MD, PhD, Eiji Kohmura, MD, PhD, Toshio Matsushima, MD, PhD, Jun Masuoka, MD, PhD, Akio Morita, MD, PhD, Shigeru Nishizawa, MD, PhD, Yoshihiro Okayama, PhD, Taku Shigeno, MD, PhD, Hiroshi Shimano, MD, PhD, Hideo Takeshima, MD, PhD, Iwao Yamakami, MD, PhD
doi : 10.1093/neuros/nyab229
Neurosurgery, Volume 89, Issue 4, October 2021, Pages 557–564
Microvascular decompression (MVD) is the most effective procedure for the long-term management of trigeminal neuralgia (TGN). However, retrospective and single-center studies are inherently biased, and there are currently no prospective, multicenter studies.
Johan Pallud, MD, PhD, Marc Zanello, MD, MSc, Alessandro Moiraghi, MD, Sophie Peeters, MD, BA, Bénédicte Trancart, MSc, Myriam Edjlali, MD, PhD, Catherine Oppenheim, MD, PhD, Pascale Varlet, MD, PhD, Fabrice Chrétien, MD, PhD, Frédéric Dhermain, MD, PhD, Alexandre Roux, MD, MSc, Edouard Dezamis, MD
doi : 10.1093/neuros/nyab254
Neurosurgery, Volume 89, Issue 4, October 2021, Pages 565–578
Insular diffuse glioma resection is at risk of vascular injury and of postoperative new neurocognitive deficits.
Johan Pallud, MD, PhD, Alexandre Roux, MD, MSc, Bénédicte Trancart, MSc, Sophie Peeters, MD, BA, Alessandro Moiraghi, MD, Myriam Edjlali, MD, PhD, Catherine Oppenheim, MD, PhD, Pascale Varlet, MD, PhD, Fabrice Chrétien, MD, PhD, Frédéric Dhermain, MD, PhD, Marc Zanello, MD, MSc, Edouard Dezamis, MD
doi : 10.1093/neuros/nyab255
Neurosurgery, Volume 89, Issue 4, October 2021, Pages 579–590
Insular diffuse glioma surgery is challenging, and tools to help surgical planning could improve the benefit-to-risk ratio.
Sapna Rawal, MD, PhD, Gabriel J E Rinkel, MD, FRCPE, Jiming Fang, PhD, Chad W Washington, MS, MD, MPHS, R Loch Macdonald, MD, J Charles Victor, MSc, Timo Krings, MD, PhD, Moira K Kapral, MD, MSc, Andreas Laupacis, MD
doi : 10.1093/neuros/nyab237
Neurosurgery, Volume 89, Issue 4, October 2021, Pages 591–596
The Nationwide Inpatient Sample Subarachnoid Hemorrhage (SAH) Severity Score (NIS-SSS) was developed as a measure of SAH severity for use in administrative databases. The NIS-SSS consists of International Classification of Diseases Ninth Revision (ICD-9) diagnostic and procedure codes derived from the SAH inpatient course and has been validated against the Hunt-Hess score (HH).
Tomas Hoikkanen, MD, Mette Nissen, MD, PhD, Tiina-Mari Ikäheimo, RN, Henna-Kaisa Jyrkkänen, MD, PhD, Jukka Huttunen, MD, PhD, Mikael von und zu Fraunberg, MD, PhD
doi : 10.1093/neuros/nyab239
Neurosurgery, Volume 89, Issue 4, October 2021, Pages 597–609
Spinal cord stimulation (SCS) is an effective treatment in chronic neuropathic pain, but its efficacy in complex regional pain syndrome (CRPS) needs to be proven.
Francesco Sammartino, MD, John Snell, PhD, Matthew Eames, PhD, Vibhor Krishna, MD, SM
doi : 10.1093/neuros/nyab238
Neurosurgery, Volume 89, Issue 4, October 2021, Pages 610–616
During focused ultrasound ablation (FUSA), the presumed stereotactic target is tested with subthreshold sonications before permanent ablation. This testing relies on ultrasound-induced reversible clinical effects (thermal neuromodulation, TN). However, the thermal dose and spot size thresholds to induce TN are not yet defined.
Vadim A Byvaltsev, MD, PhD, Andrei A Kalinin, MD, PhD, Marat A Aliyev, MD, PhD, Nurzhan O Azhibekov, MD, Valerii V Shepelev, MD, PhD, K Daniel Riew, MD
doi : 10.1093/neuros/nyab240
Neurosurgery, Volume 89, Issue 4, October 2021, Pages 617–625
Expandable cages are often used to reconstruct cervical corpectomies but there are few long-term follow-up studies with large numbers.
Mette Nissen, MD, Tiina-Mari Ikäheimo, RN, Jukka Huttunen, MD, PhD, Ville Leinonen, MD, PhD, Henna-Kaisa Jyrkkänen, MD, PhD, Mikael von und zu Fraunberg, MD, PhD
doi : 10.1093/neuros/nyab242
Neurosurgery, Volume 89, Issue 4, October 2021, Pages 626–634
Spinal cord stimulation (SCS) is an effective treatment in failed back surgery syndrome (FBSS). The effect of neuropathic pain medication use on SCS outcome is poorly understood.
James G Malcolm, MD, PhD, J Miller Douglas, BS, Alex Greven, BS, Christopher Rich, MD, Reem A Dawoud, BS, Ranliang Hu, MD, Andrew Reisner, MD, Daniel L Barrow, MD, Robert E Gross, MD, PhD, Jon T Willie, MD, PhD
doi : 10.1093/neuros/nyab241
Neurosurgery, Volume 89, Issue 4, October 2021, Pages 635–644
Magnetic resonance imaging (MRI)-guided laser interstitial thermal therapy (MRgLITT) has been used successfully to treat epileptogenic cortical cerebral cavernous malformations (CCM). It is unclear whether MRgLITT would be as feasible or safe for deep CCMs
Issam A Awad, MD
doi : 10.1093/neuros/nyab247
Neurosurgery, Volume 89, Issue 4, October 2021, Pages E207–E208
Stephanie M Robert, MD, PhD, Veronica L Chiang, MD
doi : 10.1093/neuros/nyab262
Neurosurgery, Volume 89, Issue 4, October 2021, Pages E209–E210
Jeffrey I Traylor, MD, Bradley Lega, MD
doi : 10.1093/neuros/nyab287
Neurosurgery, Volume 89, Issue 4, October 2021, Pages E211–E212
Ayman M Qureshi, MMed, FRCR, Prakash Muthusami, MD, Timo Krings, MD, PhD, Afsaneh Amirabadi, PhD, MCCPM, Ivan Radovanovic, MD, PhD, Peter Dirks, MD, PhD, Manohar Shroff, MD, Derek Armstrong, MD, Karel terBrugge, MD, Vitor M Pereira, MD, MSc
doi : 10.1093/neuros/nyab251
Neurosurgery, Volume 89, Issue 4, October 2021, Pages 645–652
Hemorrhage from brain arteriovenous malformations (bAVMs) is estimated at 3% per annum. Features influencing risk of hemorrhage include perforator/posterior circulation supply, associated aneurysms, and deep drainage. Children are more likely to present with bAVM bleeds.
Rahul A Sastry, MD, Nathan J Pertsch, BA, Emilija Sagaityte, BS, Jonathan A Poggi, MD, Steven A Toms, MD, MPH, Robert J Weil, MD
doi : 10.1093/neuros/nyab250
Neurosurgery, Volume 89, Issue 4, October 2021, Pages 653–663
Carotid endarterectomy (CEA) and carotid artery stenting (CAS) represent options to treat many patients with carotid stenosis. Although randomized trial data are plentiful, estimated rates of morbidity and mortality for both CEA and CAS have varied substantially.
Vanessa M Swiatek, cand med, Belal Neyazi, MD, Jorge A Roa, MD, Mario Zanaty, MD, Edgar A Samaniego, MD, MS, Daizo Ishii, MD, Yongjun Lu, PhD, I Erol Sandalcioglu, MD, Sylvia Saalfeld, PhD, Philipp Berg, PhD, David M Hasan, MD
doi : 10.1093/neuros/nyab249
Neurosurgery, Volume 89, Issue 4, October 2021, Pages 664–671
High-resolution vessel wall imaging plays an increasingly important role in assessing the risk of aneurysm rupture.
Anthony Larson, BS, Waleed Brinjikji, MD
doi : 10.1093/neuros/nyab265
Neurosurgery, Volume 89, Issue 4, October 2021, Pages E213–E214
Tyler Scullen, MD, Mansour Mathkour, MD, Nikhil Teja, MD, Aaron S Dumont, MD, MBA
doi : 10.1093/neuros/nyab279
Neurosurgery, Volume 89, Issue 4, October 2021, Pages E215–E217
Rebecca M Burke, MD, PhD, Ching-Jen Chen, MD, Dale Ding, MD, Thomas J Buell, MD, Jennifer Sokolowski, MD, PhD, Kimball A Sheehan, Cheng-Chia Lee, MD, PhD, Darrah E Sheehan, Hideyuki Kano, MD, PhD, Kathryn N Kearns, BS, Shih-Wei Tzeng, MD, Huai-che Yang, MD, Paul P Huang, MD, Douglas Kondziolka, MD, Natasha Ironside, MBChB, David Mathieu, MD, Christian Iorio-Morin, MD, PhD, Inga S Grills, MD, Caleb Feliciano, MD, Gene Barnett, MD, Robert M Starke, MD, L Dade Lunsford, MD, Jason P Sheehan, MD, PhD on behalf of the International Radiosurgery Research Foundation
doi : 10.1093/neuros/nyab245
Neurosurgery, Volume 89, Issue 4, October 2021, Pages 672–679
Pediatric brain arteriovenous malformations (AVMs) are a significant cause of morbidity but the role of multimodal therapy in the treatment of these lesions is not well understood.
Andrew Faramand, MD, MSc, Nima Alan, MD, Hideuyki Kano, MD, PhD, Ajay Niranjan, MD, MBA, Nitin Agarwal, MD, Alp Ozpinar, MD, John Flickinger, MD, L Dade Lunsford, MD
doi : 10.1093/neuros/nyab256
Neurosurgery, Volume 89, Issue 4, October 2021, Pages 680–685
Stereotactic radiosurgery (SRS) is widely accepted as a minimally invasive alternative to surgery in the management of arteriovenous malformations (AVMs). Dilated AVM outflow veins or varices may be caused by high-flow or partial outflow obstruction, which may increase the risk of a hemorrhage before or after SRS.
Douglas Kondziolka, MD
doi : 10.1093/neuros/nyab272
Neurosurgery, Volume 89, Issue 4, October 2021, Page E218
Matthew J Koch, MD, Richard Bram, MD, Sepideh Amin-Hanjani, MD
doi : 10.1093/neuros/nyab281
Neurosurgery, Volume 89, Issue 4, October 2021, Pages E219–E220
Veronica Parisi, MD, Brian Nils Lundstrom, MD, PhD, Panagiotis Kerezoudis, MD, Juan Luis Alcala Zermeno, MD, Gregory A Worrell, MD, PhD, Jamie J Van Gompel, MD
doi : 10.1093/neuros/nyab253
Neurosurgery, Volume 89, Issue 4, October 2021, Pages 686–694
The Food and Drug Administration approved the deep brain stimulation of the anterior nucleus of the thalamus (ANT-DBS) as an adjunctive therapy for drug-resistant epilepsy (DRE) in the United States in 2018. The DBS Therapy for Epilepsy Post-Approval Study is further evaluating the safety and effectiveness of ANT-DBS among different patients’ groups. For this study, devices for vagus nerve stimulation (VNS) must be removed prior to enrolment.
Oliver Y Tang, BS, James S Yoon, BS, Wesley M Durand, MD, Shaan A Ahmed, MD, Michael T Lawton, MD
doi : 10.1093/neuros/nyab258
Neurosurgery, Volume 89, Issue 4, October 2021, Pages 695–703
Interhospital competition has been shown to affect surgical outcomes and expenditures. However, interhospital competition's impact on neurosurgery is poorly characterized.
Sasha Gulati, MD, PhD, Vetle Vangen-Lønne, MS, Øystein P Nygaard, MD, PhD, Agnete M Gulati, MD, PhD, Tommy A Hammer, MD, Tonje O Johansen, MD, Wilco C Peul, MD, PhD, Øyvind O Salvesen, MSc, PhD, Tore K Solberg, MD, PhD
doi : 10.1093/neuros/nyab259
Neurosurgery, Volume 89, Issue 4, October 2021, Pages 704–711
Indications and optimal timing for surgical treatment of degenerative cervical myelopathy (DCM) remain unclear, and data from daily clinical practice are warranted.
Timothy Y Wang, MD, Khoi D Than, MD
doi : 10.1093/neuros/nyab263
Neurosurgery, Volume 89, Issue 4, October 2021, Pages E221–E222
Adham M Khalafallah, MD, Maureen Rakovec, BA, Chetan Bettegowda, MD, PhD, Christopher M Jackson, MD, Gary L Gallia, MD, PhD, Jon D Weingart, MD, Michael Lim, MD, Yoshua Esquenazi, MD, Brad E Zacharia, MD, MS, Ezequiel Goldschmidt, MD, PhD, Mateo Ziu, MD, MBA, Michael E Ivan, MD, MBS, Andrew S Venteicher, MD, PhD, Edjah K Nduom, MD, Adam N Mamelak, MD, Ray M Chu, MD, John S Yu, MD, Jason P Sheehan, MD, PhD, Brian V Nahed, MD, MSc, Bob S Carter, MD, PhD, Mitchel S Berger, MD, Raymond Sawaya, MD, Debraj Mukherjee, MD, MPH
doi : 10.1093/neuros/nyab257
Neurosurgery, Volume 89, Issue 4, October 2021, Pages 712–719
Gross total resection (GTR) of contrast-enhancing tumor is associated with increased survival in primary glioblastoma. Recently, there has been increasing interest in performing supratotal resections (SpTRs) for glioblastoma.
Dana C Holl, MSc, Aswin Chari, MRCS, Christian Iorio-Morin, PhD, FRCS, Ruben Dammers, PhD, Niels A van der Gaag, PhD, Angelos G Kolias, PhD, FRCS (SN), Peter J Hutchinson, PhD, FRCS (SN), Ellie Edlmann, PhD on behalf of the CODE-CSDH Advisory Group
doi : 10.1093/neuros/nyab268
Neurosurgery, Volume 89, Issue 4, October 2021, Pages 720–725
Core Outcome Sets (COSs) are necessary to standardize reporting in research studies. This is urgently required in the field of chronic subdural hematoma (CSDH), one of the most common disease entities managed in neurosurgery and the topic of several recent trials. To complement the development of a COS, a standardized definition and baseline Data Elements (DEs) to be collected in CSDH patients, would further improve study quality and comparability in this heterogeneous population.
Stephanie M Casillo, BS, Anisha Venkatesh, BS, Nallammai Muthiah, BS, Michael M McDowell, MD, Nitin Agarwal, MD
doi : 10.1093/neuros/nyab246
Neurosurgery, Volume 89, Issue 4, October 2021, Pages E223–E228
Dr Dorothy Klenke Nash (1898-1976) became the first female neurosurgeon in the United States in 1928 and maintained her status as the country's only female neurosurgeon until 1960. She graduated with her medical degree from the Columbia College of Physicians and Surgeons in 1927 and then trained at the Neurologic Institute of New York under Dr Byron Stookey. During her training, she contributed to the advancement of neurosurgical practice through academic research. In 1931, she married Charles B. Nash, and together they had 2 children, George (1932) and Dorothy Patricia (1937). Dr Nash became a senior surgeon at St. Margaret's Hospital in Pittsburgh in 1942. Shortly thereafter, she joined the inaugural University of Pittsburgh Department of Neurosurgery led by Dr Stuart N. Rowe and became an instructor of neurosurgery at the University of Pittsburgh School of Medicine. In acknowledgment of her advocacy for public access to services for mental health and cerebral palsy, Dr Nash was recognized as a Distinguished Daughter of Pennsylvania (1953) and honored by Mercy Hospital (1957), Bryn Mawr College (1960), and Columbia University (1968). She retired from neurosurgical practice in 1965, at which time she devoted herself to her grandchildren and her Catholic faith. She died on March 5, 1976 at the age of 77. With unwavering tenacity, Dr Nash paved the way for all women in neurosurgery.
Hung Tzu Wen, MD, Toshio Matsushima, MD, PhD, Jacques J Morcos, MD, Rhoton Society
doi : 10.1093/neuros/nyab252
Neurosurgery, Volume 89, Issue 4, October 2021, Pages E229–E232
Dr Evandro de Oliveira, one of the most acclaimed and recognized names in neurosurgery, anywhere in the world, tragically left us on February 11, 2021, at the age of 75.
Hani Chanbour, MD, Scott L Zuckerman, MD, MPH
doi : 10.1093/neuros/nyab248
Neurosurgery, Volume 89, Issue 4, October 2021, Pages E233–E234
Myron L Rolle, MD, MSc, Deen L Garba, BSPH, Vanessa B Kerry, MD, MSc, Brian V Nahed, MD, MSc
doi : 10.1093/neuros/nyab277
Neurosurgery, Volume 89, Issue 4, October 2021, Pages E235–E236
Alfredo Lucas, MSc, James H Eberwine, PhD, Stephen J Bagley, MD, MSCE, Yi Fan, MD, PhD, MacLean Nasrallah, MD, PhD, Steven Brem, MD
doi : 10.1093/neuros/nyab280
Neurosurgery, Volume 89, Issue 4, October 2021, Pages E237–E238
This article has been withdrawn due to an error that caused the article to be duplicated. The definitive version of this article is published under DOI 10.1093/neuros/nyab288.
Sandra Marcela Mass-Ramirez, MS, Ivan David Lozada-Martínez, MS, Amit Agrawal, MCh, Luis Rafael Moscote-Salazar, MD, Yelson Alejandro Picón-Jaimes, MD, William Florez-Perdomo, MD, Rakesh Mishra, MCh
doi : 10.1093/neuros/nyab243
Neurosurgery, Volume 89, Issue 4, October 2021, Pages E239–E240
Priyank Khandelwal, MD, Adam A Dmytriw, MD, MPH, MSc, Dileep R Yavagal, MD, MBBS
doi : 10.1093/neuros/nyab244
Neurosurgery, Volume 89, Issue 4, October 2021, Page E241
Raphia Rahman, MBS, Sabrina Rahman, MPH, Hira Ghani, BA, Md Moshiur Rahman, MS
doi : 10.1093/neuros/nyab260
Neurosurgery, Volume 89, Issue 4, October 2021, Pages E242–E243
Thomas M Zervos, MD, Karam Asmaro, MD, Ellen L Air, MD, PhD
doi : 10.1093/neuros/nyab266
Neurosurgery, Volume 89, Issue 4, October 2021, Page E244
Nathan Beucler, MD
doi : 10.1093/neuros/nyab261
Neurosurgery, Volume 89, Issue 4, October 2021, Pages E245–E246
Sean P Polster, MD, Issam A Awad, MD
doi : 10.1093/neuros/nyab264
Neurosurgery, Volume 89, Issue 4, October 2021, Pages E247–E248
Gideon Adegboyega, BSc, MBBS(C), Ahmad Ozair, MBBS(C), Ulrick Sidney Kanmounye, MD, Soham Bandyopadhyay, BA (Hons), BM, BCh (Oxon), Babar Vaqas, BM, BCh (Oxon), BSc (Lond), FRCS (SN), PhD on behalf of InciSion UK Collaborative
doi : 10.1093/neuros/nyab273
Neurosurgery, Volume 89, Issue 4, October 2021, Pages E249–E251
Giuseppe Maria Della Pepa, MD, Grazia Menna, MD, Davide Quaranta, MD
doi : 10.1093/neuros/nyab274
Neurosurgery, Volume 89, Issue 4, October 2021, Page E252
Michael W Kortz, MBA, Edwin McCray, BS, Kevin O Lillehei, MD, Anthony M DiGiorgio, DO, MHA
doi : 10.1093/neuros/nyab267
Neurosurgery, Volume 89, Issue 4, October 2021, Pages E253–E254
Jin Liu, MD, Jing Tang, MD
doi : 10.1093/neuros/nyab278
Neurosurgery, Volume 89, Issue 4, October 2021, Pages E255–E256
Jacob Cherian, MD, Peter Kan, MD
doi : 10.1093/neuros/nyab276
Neurosurgery, Volume 89, Issue 4, October 2021, Pages E257–E258
Yoshiki Hanaoka, MD, PhD, Jun-ichi Koyama, MD, PhD, Toshihiro Ogiwara, MD, PhD, Tetsuyoshi Horiuchi, MD, PhD
doi : 10.1093/neuros/nyab271
Neurosurgery, Volume 89, Issue 4, October 2021, Pages E259–E260
Ahmad Sweid, MD, Kareem El Naamani, MD, Rawad Abbas, MD, Pascal Jabbour, MD
doi : 10.1093/neuros/nyab275
Neurosurgery, Volume 89, Issue 4, October 2021, Page E261
doi : 10.1093/neuros/nyab309
Neurosurgery, Volume 89, Issue 4, October 2021, Page 726
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