Neurosurgery




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سفارش

Central Nervous System Plasticity Influences Language and Cognitive Recovery in Adult Glioma 

Saritha Krishna, PhD, Sofia Kakaizada, BS, Nyle Almeida, BS, David Brang, PhD, Shawn Hervey-Jumper, MD

doi : 10.1093/neuros/nyaa456

Neurosurgery, Volume 89, Issue 4, October 2021, Pages 539–548

Gliomas exist within the framework of complex neuronal circuitry in which network dynamics influence both tumor biology and cognition. The generalized impairment of cognition or loss of language function is a common occurrence for glioma patients. The interface between intrinsic brain tumors such as gliomas and functional cognitive networks are poorly understood. The ability to communicate effectively is critically important for receiving oncological therapies and maintaining a high quality of life. Although the propensity of gliomas to infiltrate cortical and subcortical structures and disrupt key anatomic language pathways is well documented, there is new evidence offering insight into the network and cellular mechanisms underpinning glioma-related aphasia and aphasia recovery. In this review, we will outline the current understanding of the mechanisms of cognitive dysfunction and recovery, using aphasia as an illustrative model.

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Correlation Between Trans-Stenotic Blood Flow Velocity Differences and the Cerebral Venous Pressure Gradient in Transverse Sinus Stenosis: A Prospective 4-Dimensional Flow Magnetic Resonance Imaging Study 

Heyu Ding, MD, Pengfei Zhao, MD, Han Lv, MD, Xiaoshuai Li, MM, Xiaoyu Qiu, MM, Rong Zeng, MD, Guopeng Wang, MD, Zhenghan Yang, MD, Shusheng Gong, MD, Long Jin, MD, Zhenchang Wang, MD

doi : 10.1093/neuros/nyab222

Neurosurgery, Volume 89, Issue 4, October 2021, Pages 549–556

The relationship between trans-stenotic blood flow velocity differences and the cerebral venous pressure gradient (CVPG) in transverse sinus (TS) stenosis (TSS) has not been studied.

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Microvascular Decompression for Trigeminal Neuralgia: A Prospective, Multicenter Study 

Yoshifumi Mizobuchi, MD, PhD, Shinji Nagahiro, MD, PhD, Akinori Kondo, MD, PhD, Kazunori Arita, MD, PhD, Isao Date, MD, PhD, Yukihiko Fujii, MD, PhD, Takamitsu Fujimaki, MD, PhD, Ryosuke Hanaya, MD, PhD, Mitsuhiro Hasegawa, MD, PhD, Toru Hatayama, MD, PhD, Tooru Inoue, MD, PhD, Hidetoshi Kasuya, MD, PhD, Masahito Kobayashi, MD, PhD, Eiji Kohmura, MD, PhD, Toshio Matsushima, MD, PhD, Jun Masuoka, MD, PhD, Akio Morita, MD, PhD, Shigeru Nishizawa, MD, PhD, Yoshihiro Okayama, PhD, Taku Shigeno, MD, PhD, Hiroshi Shimano, MD, PhD, Hideo Takeshima, MD, PhD, Iwao Yamakami, MD, PhD

doi : 10.1093/neuros/nyab229

Neurosurgery, Volume 89, Issue 4, October 2021, Pages 557–564

Microvascular decompression (MVD) is the most effective procedure for the long-term management of trigeminal neuralgia (TGN). However, retrospective and single-center studies are inherently biased, and there are currently no prospective, multicenter studies.

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Surgery of Insular Diffuse Gliomas—Part 1: Transcortical Awake Resection Is Safe and Independently Improves Overall Survival 

Johan Pallud, MD, PhD, Marc Zanello, MD, MSc, Alessandro Moiraghi, MD, Sophie Peeters, MD, BA, Bénédicte Trancart, MSc, Myriam Edjlali, MD, PhD, Catherine Oppenheim, MD, PhD, Pascale Varlet, MD, PhD, Fabrice Chrétien, MD, PhD, Frédéric Dhermain, MD, PhD, Alexandre Roux, MD, MSc, Edouard Dezamis, MD

doi : 10.1093/neuros/nyab254

Neurosurgery, Volume 89, Issue 4, October 2021, Pages 565–578

Insular diffuse glioma resection is at risk of vascular injury and of postoperative new neurocognitive deficits.

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Surgery of Insular Diffuse Gliomas—Part 2: Probabilistic Cortico-Subcortical Atlas of Critical Eloquent Brain Structures and Probabilistic Resection Map During Transcortical Awake Resection 

Johan Pallud, MD, PhD, Alexandre Roux, MD, MSc, Bénédicte Trancart, MSc, Sophie Peeters, MD, BA, Alessandro Moiraghi, MD, Myriam Edjlali, MD, PhD, Catherine Oppenheim, MD, PhD, Pascale Varlet, MD, PhD, Fabrice Chrétien, MD, PhD, Frédéric Dhermain, MD, PhD, Marc Zanello, MD, MSc, Edouard Dezamis, MD

doi : 10.1093/neuros/nyab255

Neurosurgery, Volume 89, Issue 4, October 2021, Pages 579–590

Insular diffuse glioma surgery is challenging, and tools to help surgical planning could improve the benefit-to-risk ratio.

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External Validation and Modification of Nationwide Inpatient Sample Subarachnoid Hemorrhage Severity Score 

Sapna Rawal, MD, PhD, Gabriel J E Rinkel, MD, FRCPE, Jiming Fang, PhD, Chad W Washington, MS, MD, MPHS, R Loch Macdonald, MD, J Charles Victor, MSc, Timo Krings, MD, PhD, Moira K Kapral, MD, MSc, Andreas Laupacis, MD

doi : 10.1093/neuros/nyab237

Neurosurgery, Volume 89, Issue 4, October 2021, Pages 591–596

The Nationwide Inpatient Sample Subarachnoid Hemorrhage (SAH) Severity Score (NIS-SSS) was developed as a measure of SAH severity for use in administrative databases. The NIS-SSS consists of International Classification of Diseases Ninth Revision (ICD-9) diagnostic and procedure codes derived from the SAH inpatient course and has been validated against the Hunt-Hess score (HH).

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Long-Term Outcome of Spinal Cord Stimulation in Complex Regional Pain Syndrome 

Tomas Hoikkanen, MD, Mette Nissen, MD, PhD, Tiina-Mari Ikäheimo, RN, Henna-Kaisa Jyrkkänen, MD, PhD, Jukka Huttunen, MD, PhD, Mikael von und zu Fraunberg, MD, PhD

doi : 10.1093/neuros/nyab239

Neurosurgery, Volume 89, Issue 4, October 2021, Pages 597–609

Spinal cord stimulation (SCS) is an effective treatment in chronic neuropathic pain, but its efficacy in complex regional pain syndrome (CRPS) needs to be proven.

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Thermal Neuromodulation With Focused Ultrasound: Implications for the Technique of Subthreshold Testing 

Francesco Sammartino, MD, John Snell, PhD, Matthew Eames, PhD, Vibhor Krishna, MD, SM

doi : 10.1093/neuros/nyab238

Neurosurgery, Volume 89, Issue 4, October 2021, Pages 610–616

During focused ultrasound ablation (FUSA), the presumed stereotactic target is tested with subthreshold sonications before permanent ablation. This testing relies on ultrasound-induced reversible clinical effects (thermal neuromodulation, TN). However, the thermal dose and spot size thresholds to induce TN are not yet defined.

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Poor Fusion Rates Following Cervical Corpectomy Reconstructed With an Expandable Cage: Minimum 2-Year Radiographic and Clinical Outcomes 

Vadim A Byvaltsev, MD, PhD, Andrei A Kalinin, MD, PhD, Marat A Aliyev, MD, PhD, Nurzhan O Azhibekov, MD, Valerii V Shepelev, MD, PhD, K Daniel Riew, MD

doi : 10.1093/neuros/nyab240

Neurosurgery, Volume 89, Issue 4, October 2021, Pages 617–625

Expandable cages are often used to reconstruct cervical corpectomies but there are few long-term follow-up studies with large numbers.

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Gabapentinoids Associated With Lower Explantation Rate in 203 Patients With Spinal Cord Stimulation for Failed Back Surgery Syndrome 

Mette Nissen, MD, Tiina-Mari Ikäheimo, RN, Jukka Huttunen, MD, PhD, Ville Leinonen, MD, PhD, Henna-Kaisa Jyrkkänen, MD, PhD, Mikael von und zu Fraunberg, MD, PhD

doi : 10.1093/neuros/nyab242

Neurosurgery, Volume 89, Issue 4, October 2021, Pages 626–634

Spinal cord stimulation (SCS) is an effective treatment in failed back surgery syndrome (FBSS). The effect of neuropathic pain medication use on SCS outcome is poorly understood.

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Feasibility and Morbidity of Magnetic Resonance Imaging-Guided Stereotactic Laser Ablation of Deep Cerebral Cavernous Malformations: A Report of 4 Cases 

James G Malcolm, MD, PhD, J Miller Douglas, BS, Alex Greven, BS, Christopher Rich, MD, Reem A Dawoud, BS, Ranliang Hu, MD, Andrew Reisner, MD, Daniel L Barrow, MD, Robert E Gross, MD, PhD, Jon T Willie, MD, PhD

doi : 10.1093/neuros/nyab241

Neurosurgery, Volume 89, Issue 4, October 2021, Pages 635–644

Magnetic resonance imaging (MRI)-guided laser interstitial thermal therapy (MRgLITT) has been used successfully to treat epileptogenic cortical cerebral cavernous malformations (CCM). It is unclear whether MRgLITT would be as feasible or safe for deep CCMs

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Commentary: Feasibility and Morbidity of Magnetic Resonance Imaging-Guided Stereotactic Laser Ablation of Deep Cerebral Cavernous Malformations: A Report of 4 Cases 

Issam A Awad, MD

doi : 10.1093/neuros/nyab247

Neurosurgery, Volume 89, Issue 4, October 2021, Pages E207–E208

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Commentary: Feasibility and Morbidity of Magnetic Resonance Imaging-Guided Stereotactic Laser Ablation of Deep Cerebral Cavernous Malformations: A Report of 4 Cases

Stephanie M Robert, MD, PhD, Veronica L Chiang, MD

doi : 10.1093/neuros/nyab262

Neurosurgery, Volume 89, Issue 4, October 2021, Pages E209–E210

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Commentary: Feasibility and Morbidity of Magnetic Resonance Imaging-Guided Stereotactic Laser Ablation of Deep Cerebral Cavernous Malformations: A Report of 4 Cases

Jeffrey I Traylor, MD, Bradley Lega, MD

doi : 10.1093/neuros/nyab287

Neurosurgery, Volume 89, Issue 4, October 2021, Pages E211–E212

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Clinical and Angioarchitectural Features of Hemorrhagic Brain Arterio-Venous Malformations in Adults and Children: Contrasts and Implications on Outcome 

Ayman M Qureshi, MMed, FRCR, Prakash Muthusami, MD, Timo Krings, MD, PhD, Afsaneh Amirabadi, PhD, MCCPM, Ivan Radovanovic, MD, PhD, Peter Dirks, MD, PhD, Manohar Shroff, MD, Derek Armstrong, MD, Karel terBrugge, MD, Vitor M Pereira, MD, MSc

doi : 10.1093/neuros/nyab251

Neurosurgery, Volume 89, Issue 4, October 2021, Pages 645–652

Hemorrhage from brain arteriovenous malformations (bAVMs) is estimated at 3% per annum. Features influencing risk of hemorrhage include perforator/posterior circulation supply, associated aneurysms, and deep drainage. Children are more likely to present with bAVM bleeds.

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Early Outcomes After Carotid Endarterectomy and Carotid Artery Stenting: A Propensity-Matched Cohort Analysis

Rahul A Sastry, MD, Nathan J Pertsch, BA, Emilija Sagaityte, BS, Jonathan A Poggi, MD, Steven A Toms, MD, MPH, Robert J Weil, MD 

doi : 10.1093/neuros/nyab250

Neurosurgery, Volume 89, Issue 4, October 2021, Pages 653–663

Carotid endarterectomy (CEA) and carotid artery stenting (CAS) represent options to treat many patients with carotid stenosis. Although randomized trial data are plentiful, estimated rates of morbidity and mortality for both CEA and CAS have varied substantially.

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Aneurysm Wall Enhancement Is Associated With Decreased Intrasaccular IL-10 and Morphological Features of Instability 

Vanessa M Swiatek, cand med, Belal Neyazi, MD, Jorge A Roa, MD, Mario Zanaty, MD, Edgar A Samaniego, MD, MS, Daizo Ishii, MD, Yongjun Lu, PhD, I Erol Sandalcioglu, MD, Sylvia Saalfeld, PhD, Philipp Berg, PhD, David M Hasan, MD

doi : 10.1093/neuros/nyab249

Neurosurgery, Volume 89, Issue 4, October 2021, Pages 664–671

High-resolution vessel wall imaging plays an increasingly important role in assessing the risk of aneurysm rupture.

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Commentary: Aneurysm Wall Enhancement Is Associated With Decreased Intrasaccular IL-10 and Morphological Features of Instability 

Anthony Larson, BS, Waleed Brinjikji, MD

doi : 10.1093/neuros/nyab265

Neurosurgery, Volume 89, Issue 4, October 2021, Pages E213–E214

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Commentary: Aneurysm Wall Enhancement Is Associated With Decreased Intrasaccular IL-10 and Morphological Features of Instability 

Tyler Scullen, MD, Mansour Mathkour, MD, Nikhil Teja, MD, Aaron S Dumont, MD, MBA

doi : 10.1093/neuros/nyab279

Neurosurgery, Volume 89, Issue 4, October 2021, Pages E215–E217

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Effect of Prior Embolization on Outcomes After Stereotactic Radiosurgery for Pediatric Brain Arteriovenous Malformations: An International Multicenter Study 

Rebecca M Burke, MD, PhD, Ching-Jen Chen, MD, Dale Ding, MD, Thomas J Buell, MD, Jennifer Sokolowski, MD, PhD, Kimball A Sheehan, Cheng-Chia Lee, MD, PhD, Darrah E Sheehan, Hideyuki Kano, MD, PhD, Kathryn N Kearns, BS, Shih-Wei Tzeng, MD, Huai-che Yang, MD, Paul P Huang, MD, Douglas Kondziolka, MD, Natasha Ironside, MBChB, David Mathieu, MD, Christian Iorio-Morin, MD, PhD, Inga S Grills, MD, Caleb Feliciano, MD, Gene Barnett, MD, Robert M Starke, MD, L Dade Lunsford, MD, Jason P Sheehan, MD, PhD on behalf of the International Radiosurgery Research Foundation

doi : 10.1093/neuros/nyab245

Neurosurgery, Volume 89, Issue 4, October 2021, Pages 672–679

Pediatric brain arteriovenous malformations (AVMs) are a significant cause of morbidity but the role of multimodal therapy in the treatment of these lesions is not well understood.

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Does Variceal Drainage Affect Arteriovenous Malformation Obliteration and Hemorrhage Rates After Stereotactic Radiosurgery? A Case-Matched Analysis 

Andrew Faramand, MD, MSc, Nima Alan, MD, Hideuyki Kano, MD, PhD, Ajay Niranjan, MD, MBA, Nitin Agarwal, MD, Alp Ozpinar, MD, John Flickinger, MD, L Dade Lunsford, MD

doi : 10.1093/neuros/nyab256

Neurosurgery, Volume 89, Issue 4, October 2021, Pages 680–685

Stereotactic radiosurgery (SRS) is widely accepted as a minimally invasive alternative to surgery in the management of arteriovenous malformations (AVMs). Dilated AVM outflow veins or varices may be caused by high-flow or partial outflow obstruction, which may increase the risk of a hemorrhage before or after SRS.

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Commentary: Does Variceal Drainage Affect Arteriovenous Malformation Obliteration and Hemorrhage Rates After Stereotactic Radiosurgery? A Case-Matched Analysis

Douglas Kondziolka, MD

doi : 10.1093/neuros/nyab272

Neurosurgery, Volume 89, Issue 4, October 2021, Page E218

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Commentary: Does Variceal Drainage Affect Arteriovenous Malformation Obliteration and Hemorrhage Rates After Stereotactic Radiosurgery? A Case-Matched Analysis 

Matthew J Koch, MD, Richard Bram, MD, Sepideh Amin-Hanjani, MD

doi : 10.1093/neuros/nyab281

Neurosurgery, Volume 89, Issue 4, October 2021, Pages E219–E220

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Anterior Nucleus of the Thalamus Deep Brain Stimulation with Concomitant Vagus Nerve Stimulation for Drug-Resistant Epilepsy 

Veronica Parisi, MD, Brian Nils Lundstrom, MD, PhD, Panagiotis Kerezoudis, MD, Juan Luis Alcala Zermeno, MD, Gregory A Worrell, MD, PhD, Jamie J Van Gompel, MD

doi : 10.1093/neuros/nyab253

Neurosurgery, Volume 89, Issue 4, October 2021, Pages 686–694

The Food and Drug Administration approved the deep brain stimulation of the anterior nucleus of the thalamus (ANT-DBS) as an adjunctive therapy for drug-resistant epilepsy (DRE) in the United States in 2018. The DBS Therapy for Epilepsy Post-Approval Study is further evaluating the safety and effectiveness of ANT-DBS among different patients’ groups. For this study, devices for vagus nerve stimulation (VNS) must be removed prior to enrolment.

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The Impact of Interhospital Competition on Treatment Strategy and Outcomes for Unruptured Intracranial Aneurysms 

Oliver Y Tang, BS, James S Yoon, BS, Wesley M Durand, MD, Shaan A Ahmed, MD, Michael T Lawton, MD

doi : 10.1093/neuros/nyab258

Neurosurgery, Volume 89, Issue 4, October 2021, Pages 695–703

Interhospital competition has been shown to affect surgical outcomes and expenditures. However, interhospital competition's impact on neurosurgery is poorly characterized.

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Surgery for Degenerative Cervical Myelopathy: A Nationwide Registry-Based Observational Study With Patient-Reported Outcomes 

Sasha Gulati, MD, PhD, Vetle Vangen-Lønne, MS, Øystein P Nygaard, MD, PhD, Agnete M Gulati, MD, PhD, Tommy A Hammer, MD, Tonje O Johansen, MD, Wilco C Peul, MD, PhD, Øyvind O Salvesen, MSc, PhD, Tore K Solberg, MD, PhD

doi : 10.1093/neuros/nyab259

Neurosurgery, Volume 89, Issue 4, October 2021, Pages 704–711

Indications and optimal timing for surgical treatment of degenerative cervical myelopathy (DCM) remain unclear, and data from daily clinical practice are warranted.

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Commentary: Surgery for Degenerative Cervical Myelopathy: A Nationwide Registry-Based Observational Study With Patient-Reported Outcomes 

Timothy Y Wang, MD, Khoi D Than, MD

doi : 10.1093/neuros/nyab263

Neurosurgery, Volume 89, Issue 4, October 2021, Pages E221–E222

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A Crowdsourced Consensus on Supratotal Resection Versus Gross Total Resection for Anatomically Distinct Primary Glioblastoma 

Adham M Khalafallah, MD, Maureen Rakovec, BA, Chetan Bettegowda, MD, PhD, Christopher M Jackson, MD, Gary L Gallia, MD, PhD, Jon D Weingart, MD, Michael Lim, MD, Yoshua Esquenazi, MD, Brad E Zacharia, MD, MS, Ezequiel Goldschmidt, MD, PhD, Mateo Ziu, MD, MBA, Michael E Ivan, MD, MBS, Andrew S Venteicher, MD, PhD, Edjah K Nduom, MD, Adam N Mamelak, MD, Ray M Chu, MD, John S Yu, MD, Jason P Sheehan, MD, PhD, Brian V Nahed, MD, MSc, Bob S Carter, MD, PhD, Mitchel S Berger, MD, Raymond Sawaya, MD, Debraj Mukherjee, MD, MPH

doi : 10.1093/neuros/nyab257

Neurosurgery, Volume 89, Issue 4, October 2021, Pages 712–719

Gross total resection (GTR) of contrast-enhancing tumor is associated with increased survival in primary glioblastoma. Recently, there has been increasing interest in performing supratotal resections (SpTRs) for glioblastoma.

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Study Protocol on Defining Core Outcomes and Data Elements in Chronic Subdural Haematoma 

Dana C Holl, MSc, Aswin Chari, MRCS, Christian Iorio-Morin, PhD, FRCS, Ruben Dammers, PhD, Niels A van der Gaag, PhD, Angelos G Kolias, PhD, FRCS (SN), Peter J Hutchinson, PhD, FRCS (SN), Ellie Edlmann, PhD on behalf of the CODE-CSDH Advisory Group

doi : 10.1093/neuros/nyab268

Neurosurgery, Volume 89, Issue 4, October 2021, Pages 720–725

Core Outcome Sets (COSs) are necessary to standardize reporting in research studies. This is urgently required in the field of chronic subdural hematoma (CSDH), one of the most common disease entities managed in neurosurgery and the topic of several recent trials. To complement the development of a COS, a standardized definition and baseline Data Elements (DEs) to be collected in CSDH patients, would further improve study quality and comparability in this heterogeneous population.

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First Female Neurosurgeon in the United States: Dorothy Klenke Nash, MD 

Stephanie M Casillo, BS, Anisha Venkatesh, BS, Nallammai Muthiah, BS, Michael M McDowell, MD, Nitin Agarwal, MD

doi : 10.1093/neuros/nyab246

Neurosurgery, Volume 89, Issue 4, October 2021, Pages E223–E228

Dr Dorothy Klenke Nash (1898-1976) became the first female neurosurgeon in the United States in 1928 and maintained her status as the country's only female neurosurgeon until 1960. She graduated with her medical degree from the Columbia College of Physicians and Surgeons in 1927 and then trained at the Neurologic Institute of New York under Dr Byron Stookey. During her training, she contributed to the advancement of neurosurgical practice through academic research. In 1931, she married Charles B. Nash, and together they had 2 children, George (1932) and Dorothy Patricia (1937). Dr Nash became a senior surgeon at St. Margaret's Hospital in Pittsburgh in 1942. Shortly thereafter, she joined the inaugural University of Pittsburgh Department of Neurosurgery led by Dr Stuart N. Rowe and became an instructor of neurosurgery at the University of Pittsburgh School of Medicine. In acknowledgment of her advocacy for public access to services for mental health and cerebral palsy, Dr Nash was recognized as a Distinguished Daughter of Pennsylvania (1953) and honored by Mercy Hospital (1957), Bryn Mawr College (1960), and Columbia University (1968). She retired from neurosurgical practice in 1965, at which time she devoted herself to her grandchildren and her Catholic faith. She died on March 5, 1976 at the age of 77. With unwavering tenacity, Dr Nash paved the way for all women in neurosurgery.

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Evandro Pinto da Luz de Oliveira, MD, PhD (November 8, 1945-February 11, 2021): A Giant of Microneurosurgery and Neuroanatomy 

Hung Tzu Wen, MD, Toshio Matsushima, MD, PhD, Jacques J Morcos, MD, Rhoton Society

doi : 10.1093/neuros/nyab252

Neurosurgery, Volume 89, Issue 4, October 2021, Pages E229–E232

Dr Evandro de Oliveira, one of the most acclaimed and recognized names in neurosurgery, anywhere in the world, tragically left us on February 11, 2021, at the age of 75.

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Commentary: Time-Out and Its Role in Neurosurgery

Hani Chanbour, MD, Scott L Zuckerman, MD, MPH

doi : 10.1093/neuros/nyab248

Neurosurgery, Volume 89, Issue 4, October 2021, Pages E233–E234

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Commentary: The Importance of Increased Funding Opportunities to Empower Global Neurosurgeons From Low-Middle Income Countries 

Myron L Rolle, MD, MSc, Deen L Garba, BSPH, Vanessa B Kerry, MD, MSc, Brian V Nahed, MD, MSc

doi : 10.1093/neuros/nyab277

Neurosurgery, Volume 89, Issue 4, October 2021, Pages E235–E236

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Withdrawn as duplicate: Commentary: "Zooming in" on Glioblastoma: Understanding Tumor Heterogeneity and its Clinical Implications in the Era of Single-Cell Ribonucleic Acid Sequencing 

Alfredo Lucas, MSc, James H Eberwine, PhD, Stephen J Bagley, MD, MSCE, Yi Fan, MD, PhD, MacLean Nasrallah, MD, PhD, Steven Brem, MD

doi : 10.1093/neuros/nyab280

Neurosurgery, Volume 89, Issue 4, October 2021, Pages E237–E238

This article has been withdrawn due to an error that caused the article to be duplicated. The definitive version of this article is published under DOI 10.1093/neuros/nyab288.

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Letter: Incidence, Characteristics, and Outcomes of Large Vessel Stroke in COVID-19 Cohort: An International Multicenter Study 

Sandra Marcela Mass-Ramirez, MS, Ivan David Lozada-Martínez, MS, Amit Agrawal, MCh, Luis Rafael Moscote-Salazar, MD, Yelson Alejandro Picón-Jaimes, MD, William Florez-Perdomo, MD, Rakesh Mishra, MCh

doi : 10.1093/neuros/nyab243

Neurosurgery, Volume 89, Issue 4, October 2021, Pages E239–E240

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In Reply: Incidence, Characteristics, and Outcomes of Large Vessel Stroke in COVID-19 Cohort: An International Multicenter Study 

Priyank Khandelwal, MD, Adam A Dmytriw, MD, MPH, MSc, Dileep R Yavagal, MD, MBBS

doi : 10.1093/neuros/nyab244

Neurosurgery, Volume 89, Issue 4, October 2021, Page E241

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Letter: Contemporary Analysis of Minimal Clinically Important Difference in the Neurosurgical Literature 

Raphia Rahman, MBS, Sabrina Rahman, MPH, Hira Ghani, BA, Md Moshiur Rahman, MS

doi : 10.1093/neuros/nyab260

Neurosurgery, Volume 89, Issue 4, October 2021, Pages E242–E243

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In Reply: Contemporary Analysis of Minimal Clinically Important Difference in the Neurosurgical Literature 

Thomas M Zervos, MD, Karam Asmaro, MD, Ellen L Air, MD, PhD

doi : 10.1093/neuros/nyab266

Neurosurgery, Volume 89, Issue 4, October 2021, Page E244

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Letter: Intracerebral Hemorrhage Volume Reduction and Timing of Intervention Versus Functional Benefit and Survival in the MISTIE III and STICH Trials 

Nathan Beucler, MD

doi : 10.1093/neuros/nyab261

Neurosurgery, Volume 89, Issue 4, October 2021, Pages E245–E246

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In Reply: Intracerebral Hemorrhage Volume Reduction and Timing of Intervention Versus Functional Benefit and Survival in the MISTIE III and STICH Trials 

Sean P Polster, MD, Issam A Awad, MD

doi : 10.1093/neuros/nyab264

Neurosurgery, Volume 89, Issue 4, October 2021, Pages E247–E248

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Letter: Is the Stupp Protocol an Expensive and Unsustainable Standard of Care for Glioblastoma in Low- and Middle-Income Country Settings? A Call to Action! 

Gideon Adegboyega, BSc, MBBS(C), Ahmad Ozair, MBBS(C), Ulrick Sidney Kanmounye, MD, Soham Bandyopadhyay, BA (Hons), BM, BCh (Oxon), Babar Vaqas, BM, BCh (Oxon), BSc (Lond), FRCS (SN), PhD on behalf of InciSion UK Collaborative

doi : 10.1093/neuros/nyab273

Neurosurgery, Volume 89, Issue 4, October 2021, Pages E249–E251

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Letter: Presurgical Identification of Patients With Glioblastoma at Risk for Cognitive Impairment at 3-Month Follow-up 

Giuseppe Maria Della Pepa, MD, Grazia Menna, MD, Davide Quaranta, MD

doi : 10.1093/neuros/nyab274

Neurosurgery, Volume 89, Issue 4, October 2021, Page E252

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Letter: A Novel Neurosurgery Virtual Interest Group for Disadvantaged Medical Students: Lessons Learned for the Postpandemic Era 

Michael W Kortz, MBA, Edwin McCray, BS, Kevin O Lillehei, MD, Anthony M DiGiorgio, DO, MHA

doi : 10.1093/neuros/nyab267

Neurosurgery, Volume 89, Issue 4, October 2021, Pages E253–E254

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In Reply: A Retrospective Analysis in 1347 Patients Undergoing Cement Augmentation for Osteoporotic Vertebral Compression Fracture: Is the Sandwich Vertebra at a Higher Risk of Further Fracture? 

Jin Liu, MD, Jing Tang, MD

doi : 10.1093/neuros/nyab278

Neurosurgery, Volume 89, Issue 4, October 2021, Pages E255–E256

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Letter: Postmarket American Experience With Woven EndoBridge Device: Adjudicated Multicenter Case Series 

Jacob Cherian, MD, Peter Kan, MD

doi : 10.1093/neuros/nyab276

Neurosurgery, Volume 89, Issue 4, October 2021, Pages E257–E258

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Letter: Lessons Learned After 760 Neurointerventions via the Upper Extremity Vasculature: Pearls and Pitfalls 

Yoshiki Hanaoka, MD, PhD, Jun-ichi Koyama, MD, PhD, Toshihiro Ogiwara, MD, PhD, Tetsuyoshi Horiuchi, MD, PhD

doi : 10.1093/neuros/nyab271

Neurosurgery, Volume 89, Issue 4, October 2021, Pages E259–E260

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In Reply: Lessons Learned After 760 Neurointerventions via the Upper Extremity Vasculature: Pearls and Pitfalls 

Ahmad Sweid, MD, Kareem El Naamani, MD, Rawad Abbas, MD, Pascal Jabbour, MD

doi : 10.1093/neuros/nyab275

Neurosurgery, Volume 89, Issue 4, October 2021, Page E261

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Corrigendum to: “Intracranial Meningiomas Decrease in Volume on Magnetic Resonance Imaging After Discontinuing Progestin” by Eduard H J Voormolen, MD, PhD, Pierre Olivier Champagne, MD, Elena Roca, MD, Lorenzo Giammattei, MD, Thibault Passeri, MD, Paolo di Russo, MD, Miguel Marigil Sanchez, MD, PhD, Anne Laure Bernat, MD, Isabelle Yoldjian, MD, Sylvie Fontanel, MD, Alain Weill, MD, Emmanuel Mandonnet, MD, PhD, Sébastien Froelich, MD. Neurosurgery, nyab175, https://doi.org/10.1093/neuros/nyab175 

doi : 10.1093/neuros/nyab309

Neurosurgery, Volume 89, Issue 4, October 2021, Page 726

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