Christina Weyer-Jamora, PhD, Melissa S Brie, PsyD, Tracy L Luks, PhD, Ellen M Smith, BA, Shawn L Hervey-Jumper, MD, Jennie W Taylor, MD, MPH
doi : 10.1093/neuros/nyaa552
Neurosurgery, Volume 89, Issue 6, December 2021, Pages 945–953
Intrinsic brain tumors often occur within functional neural networks, leading to neurological impairment and disability of varying degrees. Advances in our understanding of tumor-network integration, human cognition and language processing, and multiparametric imaging, combined with refined intraoperative tumor resection techniques, have enhanced surgical management of intrinsic brain tumors within eloquent areas. However, cognitive symptoms impacting health-related quality of life, particularly processing speed, attention, concentration, working memory, and executive function, often persist after the postoperative recovery period and treatment. Multidisciplinary cognitive rehabilitation is the standard of care for addressing cognitive impairments in many neurological diseases. There is promising research to support the use of cognitive rehabilitation in adult brain tumor patients. In this review, we summarize the history and usefulness of postacute cognitive rehabilitation for adult brain tumor patients.
Viktoria Sefcikova, MSc, Gerry Christofi, MRCP(Neurol), PhD, George Samandouras, MD, FRCS
doi : 10.1093/neuros/nyab064
Neurosurgery, Volume 89, Issue 6, December 2021, Pages E295–E297
Marc Maegele, MD
doi : 10.1093/neuros/nyab358
Neurosurgery, Volume 89, Issue 6, December 2021, Pages 954–966
Traumatic brain injury (TBI) remains one of the most challenging health and socioeconomic problems of our times. Clinical courses may be complicated by hemostatic abnormalities either pre-existing or developing with TBI.
Ralph T Schär, MD, C Marvin Jesse, MD, Matteo Montalbetti, MD, Nicole Söll, Katharina Lutz, MD, Valentin Steinsiepe, MD, Mattia Branca, PhD, Andreas Raabe, MD, Stefan Zimmerli, MD
doi : 10.1093/neuros/nyab362
Neurosurgery, Volume 89, Issue 6, December 2021, Pages 967–972
Intrawound vancomycin powder is an emerging strategy to reduce surgical site infections (SSIs) in spine surgery. However, there are concerns relating to its safety profile and toxicity. Data on systemic uptake of suprafascially administered vancomycin powder following instrumented spinal fusion is lacking.
Joshua S Catapano, MD, Kavelin Rumalla, MD, Katherine Karahalios, MS, Visish M Srinivasan, MD, Mohamed A Labib, MD, Tyler S Cole, MD, Jacob F Baranoski, MD, Caleb Rutledge, MD, Redi Rahmani, MD, Ashutosh P Jadhav, MD, PhD, Andrew F Ducruet, MD, Felipe C Albuquerque, MD, Joseph M Zabramski, MD, Michael T Lawton, MD
doi : 10.1093/neuros/nyab333
Neurosurgery, Volume 89, Issue 6, December 2021, Pages 973–977
Patients with intraventricular hemorrhage (IVH) are at higher risk of hydrocephalus requiring an external ventricular drain and long-term ventriculoperitoneal shunt placement.
Yu-Lin Li, MD, Jia-Jia Wu, MD, PhD, Jie Ma, MD, Si-Si Li, MD, Xin Xue, MD, Dong Wei, MD, Chun-Lei Shan, MD, PhD, Mou-Xiong Zheng, MD, PhD, Xu-Yun Hua, MD, PhD, Jian-Guang Xu, MD, PhD
doi : 10.1093/neuros/nyab335
Neurosurgery, Volume 89, Issue 6, December 2021, Pages 978–986
Carpal tunnel syndrome (CTS) is a common peripheral entrapment neuropathy. However, CTS-related changes of brain structural covariance and structural covariance networks (SCNs) patterns have not been clearly studied.
Mariano Socolovsky, MD, PhD
doi : 10.1093/neuros/nyab367
Neurosurgery, Volume 89, Issue 6, December 2021, Pages E298–E299
Hassan Saad, MD, David P Bray, MD, J Tanner McMahon, MD, Brandon D Philbrick, MD, Reem A Dawoud, BS, J Miller Douglas, BS, Segun Adeagbo, BS, Steven K Yarmoska, PhD, Matthew Agam, MD, Jocelyn Chow, Gustavo Pradilla, MD, Jeffrey J Olson, MD, Ali Alawieh, MD, PhD, Kimberly Hoang, MD
doi : 10.1093/neuros/nyab341
Neurosurgery, Volume 89, Issue 6, December 2021, Pages 987–996
Posterior fossa tumors (PFTs) can cause hydrocephalus. Hydrocephalus can persist despite resection of PFTs in a subset of patients requiring permanent cerebrospinal fluid (CSF) diversion. Characteristics of this patient subset are not well defined.
Yasunori Nagahama, MD, Thomas M Zervos, MD, Kristina K Murata, MSN, FNP-BC, Lynette Holman, BS, Torin Karsonovich, DO, Jonathon J Parker, MD, PhD, Jia-Shu Chen, BS, H Westley Phillips, MD, Marytery Fajardo, MD, Hiroki Nariai, MD, PhD, MS, Shaun A Hussain, MD, Brenda E Porter, MD, PhD, Gerald A Grant, MD, John Ragheb, MD, Shelly Wang, MD, MPH, Brent R O’Neill, MD, Allyson L Alexander, MD, PhD, Robert J Bollo, MD, Aria Fallah, MD, MSc
doi : 10.1093/neuros/nyab343
Neurosurgery, Volume 89, Issue 6, December 2021, Pages 997–1004
Despite the well-documented utility of responsive neurostimulation (RNS, NeuroPace) in adult epilepsy patients, literature on the use of RNS in children is limited.
Michael J Feldman, MD, Alexander V Ortiz, MS, Steven G Roth, MD, Robert J Dambrino, IV MD, Aaron M Yengo-Kahn, MD, Rohan V Chitale, MD, Lola B Chambless, MD
doi : 10.1093/neuros/nyab346
Neurosurgery, Volume 89, Issue 6, December 2021, Pages 1005–1011
Letters of recommendation (LORs) are historically an important, though subjective, component of the neurosurgery residency application process. Standardized LORs (SLORs) were introduced during the 2020 to 2021 application cycle. The intent of SLORs is to allow objective comparison of applicants and to reduce bias.
Nickalus Khan, MD, Andrew J Gienapp, BA, L Madison Michael II, MD
doi : 10.1093/neuros/nyab348
Neurosurgery, Volume 89, Issue 6, December 2021, Pages E300–E301
Jason Heth, MD, Stacey Quintero Wolfe, MD
doi : 10.1093/neuros/nyab375
Neurosurgery, Volume 89, Issue 6, December 2021, Pages E302–E303
Filippo Friso, MD, Paola Rucci, PhD, Vittoria Rosetti, MD, Alessandro Carretta, MD, Carlo Bortolotti, MD, Vania Ramponi, MD, Matteo Martinoni, MD, Giorgio Palandri, MD, Matteo Zoli, MD, PhD, Filippo Badaloni, MD, Enrico Franceschi, MD, Sofia Asioli, MD, Viscardo Paolo Fabbri, MD, Arianna Rustici, MD, Maria P Foschini, MD, Alba A Brandes, MD, Diego Mazzatenta, MD, Carmelo Sturiale, MD, Alfredo Conti, MD, PhD, FEBNS
doi : 10.1093/neuros/nyab345
Neurosurgery, Volume 89, Issue 6, December 2021, Pages 1042–1051
Glioblastoma with multiple localizations (mGBMs) can be defined as multifocal, where enhancing lesions present a connection visible on magnetic resonance imaging fluid-attenuated inversion recovery imaging, or multicentric, in the absence of a clear dissemination pathway.
Thomas J Buell, MD, Justin S Smith, MD, PhD, Christopher I Shaffrey, MD, Han Jo Kim, MD, Eric O Klineberg, MD, Virginie Lafage, PhD, Renaud Lafage, MS, Themistocles S Protopsaltis, MD, Peter G Passias, MD, Gregory M Mundis, MD, Robert K Eastlack, MD, Vedat Deviren, MD, Michael P Kelly, MD, Alan H Daniels, MD, Jeff L Gum, MD, Alex Soroceanu, MD, MPH, D Kojo Hamilton, MD, Munish C Gupta, MD, Douglas C Burton, MD, Richard A Hostin, MD, Khaled M Kebaish, MD, Robert A Hart, MD, Frank J Schwab, MD, Shay Bess, MD, Christopher P Ames, MD on behalf of The International Spine Study Group (ISSG)
doi : 10.1093/neuros/nyab352
Neurosurgery, Volume 89, Issue 6, December 2021, Pages 1012–1026
Few reports focus on adults with severe scoliosis.
Mohamed Shehabeldin, MD, Brendan Eby, MD, Adam N Wallace, MD, Amber Salter, PhD, Arindam R Chatterjee, MD, Joshua W Osbun, MD, Christopher J Moran, MD, DeWitte T Cross, III, MD, Akash P Kansagra, MD
doi : 10.1093/neuros/nyab344
Neurosurgery, Volume 89, Issue 6, December 2021, Pages 1027–1032
The benefit of intravenous thrombolysis (IVT) before mechanical thrombectomy (MT) in patients with large vessel occlusion (LVO) stroke is uncertain. Conventional metrics of final modified thrombolysis in cerebral ischemia (mTICI) score and 90-d modified Rankin Scale may be insensitive to IVT effects on procedural complexity and duration.
Andrew K Chan, MD, Thomas A Wozny, MD, Erica F Bisson, MD, MPH, Brenton H Pennicooke, MD, MS, Mohamad Bydon, MD, Steven D Glassman, MD, Kevin T Foley, MD, Christopher I Shaffrey, MD, Eric A Potts, MD, Mark E Shaffrey, MD, Domagoj Coric, MD, John J Knightly, MD, Paul Park, MD, Michael Y Wang, MD, Kai-Ming Fu, MD, PhD, Jonathan R Slotkin, MD, Anthony L Asher, MD, Michael S Virk, MD, PhD, Panagiotis Kerezoudis, MD, MS, Mohammed A Alvi, MBBS, Jian Guan, MD, Regis W Haid, MD, Praveen V Mummaneni, MD, MBA
doi : 10.1093/neuros/nyab355
Neurosurgery, Volume 89, Issue 6, December 2021, Pages 1033–1041
Trials of lumbar spondylolisthesis are difficult to compare because of the heterogeneity in the populations studied.
Ali S Farooqi, BA, Austin J Borja, BA, Donald K E Detchou, BA, Gregory Glauser, MD, MBA, MA, Kaitlyn Shultz, BS, Scott D McClintock, PhD, Neil R Malhotra, MD
doi : 10.1093/neuros/nyab360
Neurosurgery, Volume 89, Issue 6, December 2021, Pages 1052–1061
Few studies have assessed the impact of overlapping surgery during different timepoints of neurosurgical procedures.
Alexander F Haddad, MD, Anthony M DiGiorgio, DO, MHA, Young M Lee, MD, Anthony T Lee, MD, PhD, John F Burke, MD, PhD, Michael C Huang, MD, Sanjay S Dhall, MD, Geoffrey T Manley, MD, PhD, Phiroz E Tarapore, MD
doi : 10.1093/neuros/nyab359
Neurosurgery, Volume 89, Issue 6, December 2021, Pages 1062–1070
Geriatric patients have the highest rates of Traumatic Brain Injury (TBI)-related hospitalization and death. This contributes to an assumption of futility in aggressive management in this population.
Joseph R Geraghty, BS, Tyler J Lung, BA, Yonatan Hirsch, BA, Eitan A Katz, BS, Tiffany Cheng, BS, Neil S Saini, Dilip K Pandey, MD, PhD, Fernando D Testai, MD, PhD
doi : 10.1093/neuros/nyab354
Neurosurgery, Volume 89, Issue 6, December 2021, Pages 1071–1079
Delayed cerebral vasospasm is a feared complication of aneurysmal subarachnoid hemorrhage (SAH).
Tyler Scullen, MD, Mansour Mathkour, MD, Arthur Wang, MD, Aimee Aysenne, MD, MPH, Aaron S Dumont, MD, MBA
doi : 10.1093/neuros/nyab370
Neurosurgery, Volume 89, Issue 6, December 2021, Pages E304–E306
Yasser Khorchid, MD, Clemens M Schirmer, MD, PhD
doi : 10.1093/neuros/nyab368
Neurosurgery, Volume 89, Issue 6, December 2021, Page E307
Alan H Daniels, MD, Wesley M Durand, MD, Renaud Lafage, MSc, Andrew S Zhang, MD, David K Hamilton, MD, Peter G Passias, MD, Han Jo Kim, MD, Themistocles Protopsaltis, MD, Virginie Lafage, PhD, Justin S Smith, MD, PhD, Christopher Shaffrey, MD, Munish Gupta, MD, Eric Klineberg, MD, Frank Schwab, MD, Doug Burton, MD, Shay Bess, MD, Christopher Ames, MD, Robert A Hart, MD on behalf of International Spine Study Group
doi : 10.1093/neuros/nyab356
Neurosurgery, Volume 89, Issue 6, December 2021, Pages 1080–1086
Lateral (ie, coronal) vertebral listhesis may contribute to disability in adult scoliosis patients.
Scott C Seaman, MD, Carolina Deifelt Streese, PhD, Kenneth Manzel, BS, Janina Kamm, PhD, Arnold H Menezes, MD, Daniel Tranel, PhD, Brian J Dlouhy, MD
doi : 10.1093/neuros/nyab353
Neurosurgery, Volume 89, Issue 6, December 2021, Pages 1087–1096
Chiari Malformation Type I (CM-I) is defined as cerebellar tonsil displacement more than 5 mm below the foramen magnum. This displacement can alter cerebrospinal fluid flow at the cervicomedullary junction resulting in Valsalva-induced headaches and syringomyelia and compress the brainstem resulting in bulbar symptoms. However, little is known about cognitive and psychological changes in CM-I.
Mohamed Macki, MD, MPH, Yazeed Haddad, BS, Raviteja Suryadevara, MD, Abed Latif Dabaja, MD, Mokbel Chedid, MD, Victor Chang, MD, PLUSS Investigators
doi : 10.1093/neuros/nyab363
Neurosurgery, Volume 89, Issue 6, December 2021, Pages 1097–1103
Despite a proven superior efficacy of prophylactic low-molecular-weight heparin (LMWH) over unfractionated heparin (UFH) in the majority of surgical specialties, chemoprophylactic techniques after spine surgery have not been established because of the fear of epidural hematomas with LMWH.
Hyun Jin Han, MD, Woosung Lee, MD, Junhyung Kim, MD, Keun Young Park, MD, PhD, Sang Kyu Park, MD, PhD, Joonho Chung, MD, PhD, Yong Bae Kim, MD, PhD
doi : 10.1093/neuros/nyab364
Neurosurgery, Volume 89, Issue 6, December 2021, Pages 1104–1111
The survival rate of aneurysmal subarachnoid hemorrhage (aSAH) has gradually increased, leading to more clinical cases of de novo intracranial aneurysms (DNIAs).
Jose Danilo Bengzon Diestro, MD, Nimer Adeeb, MD, Mahmoud Dibas, MD, William Boisseau, MD, Pablo Harker, MD, Waleed Brinjikji, MD, Sishi Xiang, MD, Evan Joyce, MD, MS, Maksim Shapiro, MD, Eytan Raz, MD, Carmen Parra-Farinas, MD, Gwynedd Pickett, MD, Naif M Alotaibi, MD, Robert W Regenhardt, MD, PhD, Joshua D Bernstock, MD, PhD, Julian Spears, MD, MS, Christoph J Griessenauer, MD, Jan-Karl Burkhardt, MD, Muhammad U Hafeez, MD, Peter Kan, MD, Ramesh Grandhi, MD, Philipp Taussky, MD, Erez Nossek, MD, Tao Hong, MD, Hongqi Zhang, MD, PhD, Lorenzo Rinaldo, MD, PhD, Giuseppe Lanzino, MD, Christopher J Stapleton, MD, James D Rabinov, MD, Aman B Patel, MD, Thomas R Marotta, MD, Daniel Roy, MD, Adam A Dmytriw, MD, MPH, MSc
doi : 10.1093/neuros/nyab365
Neurosurgery, Volume 89, Issue 6, December 2021, Pages 1112–1121
Open surgery has traditionally been preferred for the management of bifurcation middle cerebral artery (MCA) aneurysms. Flow diverting stents present a novel endovascular strategy for aneurysm treatment.
Ankur Bhambri, BS, Arjun Rohit Adapa, MS, Yang Liu, PhD, Tobias Boeckh-Behrens, MD, Václav Procházka, MD, PhD, MBA, Francisco Hernández-Fernández, MD, PhD, Rosa Angélica Barbella-Aponte, MD, PhD, Tetsuya Hashimoto, MD, PhD, Luis E Savastano, MD, PhD, Joseph J Gemmete, MD, Neeraj Chaudhary, MD, Albert J Shih, PhD, Aditya S Pandey, MD
doi : 10.1093/neuros/nyab366
Neurosurgery, Volume 89, Issue 6, December 2021, Pages 1122–1131
Appropriate thrombus-device interaction is critical for recanalization. Histology can serve as a proxy for mechanical properties, and thus inform technique selection.
Eric Suero Molina, PD Dr med., MBA, Sadahiro Kaneko, MD, PhD, David Black, Walter Stummer, Prof Dr med.
doi : 10.1093/neuros/nyab361
Neurosurgery, Volume 89, Issue 6, December 2021, Pages 1132–1140
Fluorescence-guided resections using 5-aminolevulinic acid (5-ALA)-induced tumor porphyrins have been established as an adjunct for malignant glioma surgery based on a phase III study using specifically adapted microscopes for visualizing fluorescing protoporphyrin IX (PPIX). New hardware technologies are being introduced, which claim the same performance as the original technology for visualizing fluorescence. This assumes that qualitative fluorescence detection is equivalent to the established standard, an assumption that needs to be critically assessed.
Joyce Koueik, MD, MS, Bermans J Iskandar, MD, Zhe Yang, MS, Mark R Kraemer, MD, Stephanie Armstrong, MS, Victor Wakim, BS, Aimee Teo Broman, MA, Joshua Medow, MD, PhD, Christopher Luzzio, MD, David A Hsu, MD, PhD
doi : 10.1093/neuros/nyab336
Neurosurgery, Volume 89, Issue 6, December 2021, Pages 1141–1147
There have been few improvements in cerebrospinal fluid (CSF) shunt technology since John Holter introduced the silicon valve, with overdrainage remaining a major source of complications.
Gregory W J Hawryluk, MD, PhD, FRCSC, Jamshid Ghajar, MD, PhD
doi : 10.1093/neuros/nyab357
Neurosurgery, Volume 89, Issue 6, December 2021, Pages 1148–1156
The Brain Trauma Foundation (BTF) Guidelines for the Management of Severe Head Injury were the first clinical practice guidelines published by any surgical specialty. These guidelines have earned a reputation for rigor and have been widely adopted around the world. Implementation of these guidelines has been associated with a 50% reduction in mortality and reduced costs of patient care. Over their 25-yr history the traumatic brain injury (TBI) guidelines have been expanded, refined, and made increasingly more rigorous in conjunction with new clinical evidence and evolving methodologic standards. Here, we discuss the history and accomplishments of BTF guidelines for TBI as well as their limitations. We also discuss planned changes to future TBI guidelines intended to increase their utility and positive impact in an evolving medical landscape. Perhaps the greatest limitation of TBI guidelines now is the lack of high-quality clinical research as well as novel diagnostics and treatments with which to generate substantially new recommendations.
Christine Park, BA, Oren N Gottfried, MD
doi : 10.1093/neuros/nyab327
Neurosurgery, Volume 89, Issue 6, December 2021, Pages E308–E309
Christoph Wipplinger, MD, Tamara Wipplinger, MSc, Christoph J Griessenauer, MD
doi : 10.1093/neuros/nyab374
Neurosurgery, Volume 89, Issue 6, December 2021, Pages E310–E311
Domagoj Coric, MD
doi : 10.1093/neuros/nyab330
Neurosurgery, Volume 89, Issue 6, December 2021, Pages E312–E313
Stasa Tumpa, BSc (Hons), MSc, Brandon George Smith, BSc (Hons), Oliver Burton, BSc, MB, ChB, Luis Alberto Domitrovic Zalocar, MD
doi : 10.1093/neuros/nyab371
Neurosurgery, Volume 89, Issue 6, December 2021, Pages E314–E315
Nathan A Shlobin, BA, David Moher, PhD
doi : 10.1093/neuros/nyab331
Neurosurgery, Volume 89, Issue 6, December 2021, Pages E316–E317
Kelly Gassie, MD, Alfredo Quinones-Hinojosa, MD, T Forcht Dagi, MD, DMedSc, DHC, MPH, FRCSEd
doi : 10.1093/neuros/nyab338
Neurosurgery, Volume 89, Issue 6, December 2021, Pages E318–E322
Luis M Tumialán, MD, Anand Veeravagu, MD, John K Ratliff, MD
doi : 10.1093/neuros/nyab339
Neurosurgery, Volume 89, Issue 6, December 2021, Pages E323–E324
Vin Shen Ban, MBBChir, MRCS, MSc, Salah G Aoun, MD, Rafael Sillero, MD
doi : 10.1093/neuros/nyab340
Neurosurgery, Volume 89, Issue 6, December 2021, Pages E325–E326
Kunzhe Lin, MD, Zhijie Pei, MD, Jun Li, MD, Shousen Wang, PhD
doi : 10.1093/neuros/nyab329
Neurosurgery, Volume 89, Issue 6, December 2021, Page E327
Cecile Riviere-Cazaux, BS, Luis A Antezana, BS, Katherine Z Xie, BS, Jamie J Van Gompel, MD
doi : 10.1093/neuros/nyab369
Neurosurgery, Volume 89, Issue 6, December 2021, Pages E328–E329
Lohit Velagapudi, BS, Fadi Al Saiegh, MD, Michael P Baldassari, MD, Christopher Farrell, MD, Ashwini Sharan, MD
doi : 10.1093/neuros/nyab372
Neurosurgery, Volume 89, Issue 6, December 2021, Pages E330–E331
Chidinma M Wilson, BA, BS, Donald K E Detchou, BA
doi : 10.1093/neuros/nyab373
Neurosurgery, Volume 89, Issue 6, December 2021, Page E332
Mervyn J R Lim, MBBS, MPH
doi : 10.1093/neuros/nyab337
Neurosurgery, Volume 89, Issue 6, December 2021, Pages E333–E334
T Forcht Dagi, MD, DMedSc, DHC, FRCSEd, Fred G Barker II, MD, Jacob Glass, MD, PhD
doi : 10.1093/neuros/nyab349
Neurosurgery, Volume 89, Issue 6, December 2021, Page E335
Scott L Zuckerman, MD, MPH, Aaron M Yengo-Kahn, MD, Andrew W Kuhn, MD, Gavin A Davis, MBBS, FRACS, Benjamin L Brett, PhD, Douglas P Terry, PhD
doi : 10.1093/neuros/nyab347
Neurosurgery, Volume 89, Issue 6, December 2021, Pages E336–E337
Ahmad Ozair, MBBS, Ahmed Negida, MBBCh, Abdul Karim Ghaith, MD, Ulrick Sidney Kanmounye, MD
doi : 10.1093/neuros/nyab328
Neurosurgery, Volume 89, Issue 6, December 2021, Pages E338–E339
Adrian E Jimenez, BS, Adham M Khalafallah, MD, Debraj Mukherjee, MD, MPH
doi : 10.1093/neuros/nyab332
Neurosurgery, Volume 89, Issue 6, December 2021, Page E340
Yuankun Cai, MD, TingBao Zhang, MD, Nanxiang Xiong, MD
doi : 10.1093/neuros/nyab350
Neurosurgery, Volume 89, Issue 6, December 2021, Pages E341–E342
Kyle B Mueller, MD, Matthew D’Antuono, BS, Nirali Patel, MD, Gnel Pivazyan, MD, Edward F Aulisi, MD, Karen K Evans, MD, M Nathan Nair, MD
doi : 10.1093/neuros/nyab351
Neurosurgery, Volume 89, Issue 6, December 2021, Page E343
doi : 10.1093/neuros/nyab377
Neurosurgery, Volume 89, Issue 6, December 2021, Page 1157
doi : 10.1093/neuros/nyab378
Neurosurgery, Volume 89, Issue 6, December 2021, Page 1157
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