دسترسی یکساله به بیش از ۵۰۰ ژورنال روز جهان موجود در سامانه
-
http://medilib.ir
- ﻣﺪﺕ ﺯﻣﺎﻥ : 365 ﺭﻭﺯ
قیمت : 3,800,000 تومان- قیمت ویژه : 1,900,000تومان
Endoscopic submucosal dissection in tumors extending to the dentate line compared to proximal rectal tumors: a systematic review with meta-analysis
Pérez-Cuadrado-Robles, Enriquea,,*; Chupin, Antoinea,,*; Perrod, Guillaumea; Severyns, Thomasa; Cellier, Christophea; Rahmi, Gabriela,,b
doi : 10.1097/MEG.0000000000001998
February 2022 - Volume 34 - Issue 2 - p 121-127
Endoscopic submucosal dissection (ESD) is a validated treatment for early rectal tumors, but whether this therapy is efficient or not for rectal tumors extending to the dentate line (RTDL) remains unclear. We performed a systematic review and meta-analysis to assess the effectiveness and safety of ESD in RTDL compared to non-RTDL. A search in PubMed, Scopus and the Cochrane library up to April 2020 was conducted to identify studies that compared ESD in both localizations (RTDL and non-RTDL), reporting at least one main outcome (en bloc, complete resection, recurrence). Secondary outcomes were adverse event occurrence. Five observational studies including 739 patients with a total of 201 RTDL and 538 non-RTDL were considered. The proportion of female sex (66% vs. 36.9%, P < 0.001) and tumor size [mean difference = 7.75, 95% confidence interval (CI): 3.01–12.49, P = 0.001] were higher in the RTDL group. There were no differences in en bloc resection rates between RTDL and non-RTDL groups [odds ratio (OR): 0.95, 95% CI: 0.50–1.79, P = 0.087]. The complete resection rate was significantly higher in the non-RTDL group (OR: 1.72, 95% CI: 1.18–2.53, P = 0.005, I2 = 0%). However, recurrence rates were comparable (RD: –0.04, 95% CI: –0.07 to 0.00, P = 0.06, I2 = 0%). Concerning adverse events, there were no differences in terms of perforation (OR: 0.9, 95% CI: 0.26–3.08, P = 0.86, I2 = 0%) or delayed bleeding (OR: 0.64, 95% CI: 0.17–2.42, P = 0.51, I2 = 35%). Anal pain rate was 28% (95% CI: 21.4–35.8%). ESD is an effective and safe therapeutic approach for RTDL with comparable recurrence rate to non-RTDL. The lower complete resection rate in RTDL needs to be clarified in studies.
Peroral endoscopic myotomy treatment for symptomatic esophageal diverticulum: a systematic review and meta-analysis
Ren, Lihuaa,,b; Xie, Weihuac; Mulmi Shrestha, Sachina,,b; Ji, Qinghuaa; Xie, Tingb; Lu, Xuejiab; Dong, Jingwud,,*; Shi, Ruihuab,,*
doi : 10.1097/MEG.0000000000002001
February 2022 - Volume 34 - Issue 2 - p 128-136
Peroral endoscopic myotomy (POEM) is a rapidly evolving technique for the treatment of esophageal diverticulum. The aim of this study was to perform a systematic review and meta-analysis of the literature focusing on POEM for symptomatic esophageal diverticula, including an in-depth evaluation of its efficacy, safety, and limitations. A comprehensive literature search was completed to identify articles that examined the efficacy and safety of POEM for esophageal diverticula. Heterogeneity among studies was assessed using the I2 statistic. Meta-regression and sensitivity analyses were performed to explore the sources of heterogeneity and assess potentially important covariates influencing the main outcomes. Primary endpoints such as rates of success, adverse events, and recurrences were evaluated. P values of ?0.05 were considered statistically significant. Nine studies with a total of 153 patients were enrolled. Pooled technical success, clinical success, adverse events, and recurrence rates were 99% [95% confidence interval (CI), 97–100%; I2 = 0%), 94% (95% CI, 89–97%; I2 = 24%), 2% (95% CI, 0–6%, I2 = 0%), and 0% (95% CI, 0–1%; I2 = 0%), respectively. The pooled perforation rate was 6% (95% CI, 1–11%; I2 = 0%). Meta-regression analysis indicated that esophageal diverticula types and motility disorders were not associated with the clinical success rate (P > 0.05). POEM is a feasible, safe, and effective treatment for symptomatic esophageal diverticula, with low adverse events and recurrence rates.
Pre-hospitalization proton pump inhibitor use and clinical outcomes in COVID-19
Ramachandran, Preethia,,*; Perisetti, Abhilashb,; Gajendran, Maheshc; Jean-Louis, Farlad; Bansal, Pardeepe; Dwivedi, Alok Kumarf; Goyal, Hemantg
doi : 10.1097/MEG.0000000000002013
February 2022 - Volume 34 - Issue 2 - p 137-141
Severe acute respiratory syndrome coronavirus-2 may escape the inactivation by gastric acid because of hypochlorhydria caused by proton pump inhibitors (PPIs), which could predispose the patients to severe COVID-19.
Impact of laparoscopic cholecystectomy on the complexity of endoscopic retrograde cholangiopancreatography
Seleem, Waseem M.a; Hanafy, Amr S.a; Abd-Elsalam, Sheriefb; Badawi, Rehabb
doi : 10.1097/MEG.0000000000002017
February 2022 - Volume 34 - Issue 2 - p 142-145
A scarce number of researches discussed the impact of cholecystectomies on the anatomy of common bile duct (CBD) and intern if this will affect the difficulty of endoscopic retrograde cholangiopancreatography (ERCP). The objective of present study was to assess the impact of complicated cholecystectomy on the complexity and safety of the ERCP procedure
Continuous insulin therapy versus apheresis in patients with hypertriglyceridemia-associated pancreatitis
Araz, Filiza,,b; Bakiner, Okan Sefac; Bagir, Gulay Simsekc; Soydas, Barisa,,b; Ozer, Birola,,b; Kozanoglu, Ilknurd,,e
doi : 10.1097/MEG.0000000000002025
February 2022 - Volume 34 - Issue 2 - p 146-152
The optimal treatment modality for lowering the triglyceride level in patients with hypertriglyceridemia (HTG)-associated acute pancreatitis is unknown. We evaluated the efficacy of continuous insulin infusion and apheresis procedures as triglyceride-lowering therapy.
Prevalence of inflammatory bowel disease in young Greek Army male recruits from 2006 to 2018: a 13-year retrospective study from a tertiary center
Kyriakos, Nikolaosa; Papaefthymiou, Apostolisa; Giakoumis, Mariosa; Galanopoulos, Michaila; Galanis, Petrosb; Mylonas, Iordanisa; Karatzas, Pantelisc; Mantzaris, Gerasimosd; Liatsos, Christosa
doi : 10.1097/MEG.0000000000002071
February 2022 - Volume 34 - Issue 2 - p 153-160
The prevalence and incidence of inflammatory bowel diseases (IBDs) vary among countries. Data regarding prevalence of IBD in Greece are limited or outdated.
Factors influencing health-related quality of life in patients with Barrett’s esophagus: a qualitative focus group study
van der Ende-van Loon, Mirjama; Brouwers, Marleena; de Munnik, Suzannea,,c; Nieuwkerk, Pythiab; Curvers, Woutera; Schoon, Erika
doi : 10.1097/MEG.0000000000002070
February 2022 - Volume 34 - Issue 2 - p 161-167
Barrett’s esophagus is a premalignant condition in the lower part of the esophagus, caused by gastroesophageal reflux disease. Previous studies found that having a Barrett’s esophagus is associated with a significant decrease of health-related quality of life (HRQOL). Over the past decade, a considerable amount of literature has been published on the development of endoscopic treatment for (early) neoplasia in Barrett’s esophagus. Though, currently very little is known about the impact of those endoscopic treatments on HRQOL from the perspective of patients. In this study, we aim to assess the factors influencing HRQOL according to Barrett’s esophagus patients.
Gastrointestinal symptoms are associated with severity of coronavirus disease 2019: a systematic review and meta-analysis
Zeng, Weibiaoa,,*; Qi, Kaia,,b,,*; Ye, Miaoc,,*; Zheng, Lid; Liu, Xinlianga; Hu, Shenga; Zhang, Wenxionga; Tang, Wenjingb; Xu, Jianjuna; Yu, Donglianga; Wei, Yipinga
doi : 10.1097/MEG.0000000000002072
February 2022 - Volume 34 - Issue 2 - p 168-176
Studies have suggested that coronavirus disease 2019 (COVID-19) appears to be more serious in patients with gastrointestinal symptoms. This meta-analysis was conducted to explore the relationship between gastrointestinal symptoms and the severity of COVID-19.
Impact of endoscopist experience, patient age and comorbidities on dose of sedation and sedation-related complications by endoscopic ultrasound
Razpotnik, Marcel; Bota, Simona; Essler, Gerolf; Weber-Eibel, Jutta; Peck-Radosavljevic, Markus
doi : 10.1097/MEG.0000000000002084
February 2022 - Volume 34 - Issue 2 - p 177-183
The aim of the study is to investigate the influence of endosonographer experience and patient-related factors on the dose of sedation and sedation-related complications during endoscopic ultrasound (EUS).
Rebleeding after hemoclip versus argon plasma coagulation for gastrointestinal angiodysplasias: a retrospective multicenter study
Ismail, Bahaaeldeena; Alayoubi, Mhd Suhaibb; Abdelwadoud, Moazc; Castro, Fernando J.b
doi : 10.1097/MEG.0000000000002098
February 2022 - Volume 34 - Issue 2 - p 184-191
Hemoclips are utilized for treating bleeding gastrointestinal angiodysplastic lesions (GIADs); however, the supporting evidence is limited.
Procedural bleeding risk, rather than conventional coagulation tests, predicts procedure related bleeding in cirrhosis
Janko, Natashaa,,b; Majeed, Ammara,,b; Commins, Isabellaa; Kemp, Williama,,b; Roberts, Stuart K.a,,b
doi : 10.1097/MEG.0000000000001948
February 2022 - Volume 34 - Issue 2 - p 192-199
Standard coagulation parameters are used to guide prophylactic blood product transfusion prior to invasive procedures in cirrhotic patients despite limited high-quality evidence.
A prospective cohort study of the use of the fatty liver index and Fibroscan to determine the prevalence of fatty liver disease in an Irish population
Rabbitt, Louise A.a,,b; McNally, Mairéada; Reynolds, Lauraa; Hinchion, Katea; Simpkin, Andrewb; Scarry, Margareta; Bohan-Keane, Marya; Goulding, Carola
doi : 10.1097/MEG.0000000000001951
February 2022 - Volume 34 - Issue 2 - p 200-205
Rates of nonalcoholic fatty liver disease (NAFLD) are increasing worldwide. The fatty liver index (FLI) is a noninvasive predictor of NAFLD. This prospective cohort study used the FLI to estimate the prevalence of NAFLD in patients attending an Irish Acute Medical Unit (AMU), and assessed the degree of fibrosis in this group using Fibroscan.
Safety and efficacy of outpatient continuous terlipressin infusion for the treatment of portal hypertensive complications in cirrhosis
Gow, Paul J.a,,b; Sinclair, Mariea,,b; Thwaites, Phoebe A.a; Angus, Peter W.a,,b; Chapman, Brookea; Terbah, Rymaa; Testro, Adam G.a,,b
doi : 10.1097/MEG.0000000000001950
February 2022 - Volume 34 - Issue 2 - p 206-212
Therapeutic options are limited for patients with hepatorenal syndrome (HRS), diuretic refractory ascites and hepatic hydrothorax who are awaiting liver transplant. We assessed the safety and efficacy of continuous terlipressin infusion (CTI) for treating these conditions in an outpatient setting.
Combining immune checkpoint inhibitor with lenvatinib prolongs survival than lenvatinib alone in sorafenib-experienced hepatocellular carcinoma patients
Lin, Po-Tinga,,b; Teng, Weia,,b; Jeng, Wen-Jueia,,b; Lin, Chun-Yena,,b; Lin, Shi-Minga,,b; Sheen, I-Shyana,,b
doi : 10.1097/MEG.0000000000001956
February 2022 - Volume 34 - Issue 2 - p 213-219
Lenvatinib and immune checkpoint inhibitors (ICIs) were approved as the promising agents for unresectable hepatocellular carcinoma (HCC). Nevertheless, the benefits of combining ICI with lenvatinib in sorafenib-experienced patients remain uncertain. We aimed to investigate whether the combination use of ICI and lenvatinib provides better survival than lenvatinib alone in advanced stage HCC patients.
P53 is a risk factor of de-novo hepatitis C-related hepatocellular carcinoma treated with direct-acting antivirals: a case-control study
Omran, Mohameda; Fouda, Manara; Abdelwahab, Abdelwahab Osamaa; Nabeel, Mohamed Mahmoudb; Abdelaziz, Ashraf Omarb; Omran, Daliab; Shousha, Hend Ibrahimb
doi : 10.1097/MEG.0000000000001962
February 2022 - Volume 34 - Issue 2 - p 220-226
The mechanisms underlying de-novo hepatocellular carcinoma (HCC) after direct-acting antivirals (DAAs) is still under investigation. This work aims to study P53 and hepatocyte growth factor (HGF) as possible diagnostics of de-novo hepatocellular carcinoma (HCC) following DAAs in comparison to alpha-fetoprotein (AFP).
Survival and recurrence rates of hepatocellular carcinoma after treatment of chronic hepatitis C using direct acting antivirals
Lithy, Rania M.a; Elbaz, Tamera; H. Abdelmaksoud, Ahmedb; M. Nabil, Mohameda; Rashed, Nohaa; Omran, Daliaa; Kaseb, Ahmed O.c; O. Abdelaziz, Ashrafa; I. Shousha, Henda
doi : 10.1097/MEG.0000000000001972
February 2022 - Volume 34 - Issue 2 - p 227-234
Conflicting studies were proposed either suggested or denied the relationship between early hepatocellular carcinoma (HCC) recurrence and the use of direct-acting antivirals (DAAs) for chronic hepatitis C management
Hemosuccus pancreaticus: masquerader of variceal bleed in patient with alcoholic steatohepatitis
Meena, Babu Lala; Praharaj, Dibya Lochana; Premkumar, Madhumitaa; Mehtani, Rohita; Chaluvashetty, Sreedhara B.b
doi : 10.1097/MEG.0000000000001877
February 2022 - Volume 34 - Issue 2 - p 235-236
Liver injury could be associated with severe disease in COVID-19 patients: a meta-analysis
Liu, Chuana,,b,,*; Yang, Jiahuic,,*; Wang, Wancongd,,*; Zheng, Pengyuana,,b; Tang, Youcaib,,e
doi : 10.1097/MEG.0000000000001953
February 2022 - Volume 34 - Issue 2 - p 237-238
Assessment of proton-pump inhibitor use, race, socioeconomic status, and mortality in individuals with COVID-19
Aby, Elizabeth S.a,,b; Tappata, Manaswitab; Rodin, Hollyc; Debes, Jose D.a,,b
doi : 10.1097/MEG.0000000000002138
February 2022 - Volume 34 - Issue 2 - p 239
Hereditary angioedema and pancreatitis: two diseases that should remind each other
Ismayilov, Rashada; Ismayilova, Ulkarb; Keskin, Onurc
doi : 10.1097/MEG.0000000000002305
February 2022 - Volume 34 - Issue 2 - p 240-241
Freezing of faeces dramatically decreases the viability of Blastocystis sp. and Dientamoeba fragilis
Hurych, Jakuba,,b; Vodolanova, Lucieb; Vejmelka, Jiric; Drevinek, Pavela; Kohout, Pavelc; Cinek, Ondreja,,b; Nohynkova, Evad
doi : 10.1097/MEG.0000000000002327
February 2022 - Volume 34 - Issue 2 - p 242-243
