دسترسی یکساله به بیش از ۵۰۰ ژورنال روز جهان موجود در سامانه
-
http://medilib.ir
- ﻣﺪﺕ ﺯﻣﺎﻥ : 365 ﺭﻭﺯ
قیمت : 3,800,000 تومان- قیمت ویژه : 1,900,000تومان
Educating Anesthesiologists During the Coronavirus Disease 2019 Pandemic and Beyond
Martinelli, Susan M. MD*; Chen, Fei PhD*; Isaak, Robert S. DO*; Huffmyer, Julie L. MD†; Neves, Sara E. MD‡; Mitchell, John D. MD
doi : 10.1213/ANE.0000000000005333
Anesthesia & Analgesia. 132(3):585-593, March 2021.
The coronavirus disease 2019 (COVID-19) pandemic has altered approaches to anesthesiology education by shifting educational paradigms. This vision article discusses pre–COVID-19 educational methodologies and best evidence, adaptations required under COVID-19, and evidence for these modifications, and suggests future directions for anesthesiology education. Learning management systems provide structure to online learning.
A Practical Guide for Anesthesia Providers on the Management of Coronavirus Disease 2019 Patients in the Acute Care Hospital
Abola, Ramon E. MD*; Schwartz, Jonathan A. MD*; Forrester, Joseph D. MD, MSc†; Gan, Tong J. MD, MBA, MHS*
doi : 10.1213/ANE.0000000000005295
Anesthesia & Analgesia. 132(3):594-604, March 2021.
The coronavirus disease 2019 (COVID-19) pandemic has infected millions of individuals and posed unprecedented challenges to health care systems. Acute care hospitals have been forced to expand hospital and intensive care capacity and deal with shortages in personal protective equipment. This guide will review 2 areas where the anesthesiologists will be caring for COVID-19 patients: the operating room and on airway teams. General principles for COVID-19 preparation and hospital procedures will be reviewed to serve as a resource for anesthesia departments to manage COVID-19 or future pandemics.
Changes in Pain Medicine Training Programs Associated With COVID-19: Survey Results
Kohan, Lynn MD*; Durbhakula, Shravani MD†; Zaidi, Munfarid BS‡; Phillips, Christopher R. MD§; Rowan, Cody C. MD*; Brenner, Gary J. MD, PhD?; Cohen, Steven P. MD
doi : 10.1213/ANE.0000000000005314
Anesthesia & Analgesia. 132(3):605-615, March 2021.
The coronavirus disease 2019 (COVID-19) pandemic is a public health crisis of unprecedented proportions that has altered the practice of medicine. The pandemic has required pain clinics to transition from in-person visits to telemedicine, postpone procedures, and cancel face-to-face educational sessions. There are no data on how fellowship programs have adapted.
“Test and Standard Precautions”—Is It Enough to Protect Us From False-Negative Severe Acute Respiratory Syndrome Coronavirus 2 Test Results?
Bowdle, Andrew MD, PhD, FASE*; Jelacic, Srdjan MD, FASE*; Togashi, Kei MD, MPH†; Wechter, Debra G. MD, FACS‡; Cain, Kevin PhD
doi : 10.1213/ANE.0000000000005351
Anesthesia & Analgesia. 132(3):616-621, March 2021.
Crosshairs on Cancer: Propofol Versus Inhalational Agents and Cancer Outcomes
Nathan, Naveen MD*
doi : 10.1213/ANE.0000000000005404
Anesthesia & Analgesia. 132(3):622, March 2021.
Anesthesia and Long-term Oncological Outcomes: A Systematic Review and Meta-analysis
Chang, Chun-Yu MD*,†; Wu, Meng-Yu MD†,‡; Chien, Yung-Jiun MD†,§; Su, I-Min MD†,?; Wang, Shih-Ching MD*,†; Kao, Ming-Chang MD, PhD*
doi : 10.1213/ANE.0000000000005237
Anesthesia & Analgesia. 132(3):623-634, March 2021.
Whether propofol elicits a survival benefit over volatile anesthetics during cancer surgery remains inconclusive. The primary aim of this systematic review and meta-analysis is to compare the effects of propofol-based total intravenous anesthesia (TIVA) with any volatile anesthesia on long-term oncological outcomes. The secondary aim is to compare propofol-based TIVA with specific volatile agents on long-term oncological outcomes.
The Diagnostic Accuracy of Noninvasive Methods to Measure the Intracranial Pressure: A Systematic Review and Meta-analysis
Sallam, Amr MD, FCAI*,†; Abdelaal Ahmed Mahmoud M. Alkhatip, Ahmed MD, EDAIC, FCAI‡,§; Kamel, Mohamed Gomaa MBBCh?; Hamza, Mohamed Khaled MD¶; Yassin, Hany Mahmoud MD#; Hosny, Hisham MD¶,**; Younis, Mohamed I. FCAI††; Ramadan, Eslam MD, FCAI*,†; Algameel, Haytham Zien MD‡‡; Abdelhaq, Mohamed MD¶; Abdelkader, Mohamed MD, EDAIC§; Mills, Kerry E. PhD§§; Mohamed, Hassan MD, FCAI
doi : 10.1213/ANE.0000000000005189
Anesthesia & Analgesia. 132(3):686-695, March 2021.
Although invasive monitoring is the standard method for intracranial pressure (ICP) measurement, it is not without potential for serious complications. Noninvasive methods have been proposed as alternatives to invasive ICP monitoring. The study aimed to investigate the diagnostic accuracy of the currently available noninvasive methods for intracranial hypertension (ICH) monitoring.
The Role of Waddell Signs in Low Back Pain
Benzon, Honorio T. MD*; Turk, Dennis C. PhD
doi : 10.1213/ANE.0000000000005167
Anesthesia & Analgesia. 132(3):635-638, March 2021.
Predicting Postoperative Pain: A Complex Interplay of Multiple Factors
Nelson, Ehren R. MD*; Gan, Tong J. MD, MBA, MHS, FRCA†; Urman, Richard D. MD, MBA
doi : 10.1213/ANE.0000000000005200
Anesthesia & Analgesia. 132(3):652-655, March 2021.
Can Noninferior be Superior?
Toledo, Paloma MD, MPH*,†; Singh, Preet Mohinder MD‡; Sultan, Pervez MBChB, FRCA, MD (Res)
doi : 10.1213/ANE.0000000000005267
Anesthesia & Analgesia. 132(3):663-665, March 2021.
Racial Disparities in Perioperative Outcomes in Children: Where Do We Go From Here?
Nasr, Viviane G. MD; DiNardo, James A. MD, FAAP
doi : 10.1213/ANE.0000000000005383
Anesthesia & Analgesia. 132(3):676-678, March 2021.
Waddell (Nonorganic) Signs and Their Association With Interventional Treatment Outcomes for Low Back Pain
Cohen, Steven P. MD*,†,‡,§; Doshi, Tina L. MD*; Kurihara, Connie RN‡,§; Dolomisiewicz, Edward MD‡; Liu, Richard C. MD§; Dawson, Timothy C. MD?; Hager, Nelson MD‡; Durbhakula, Shravani MD*; Verdun, Aubrey V. MD§; Hodgson, John A. MD§; Pasquina, Paul F. MD
doi : 10.1213/ANE.0000000000005054
Anesthesia & Analgesia. 132(3):639-651, March 2021.
The rising use of injections to treat low back pain (LBP) has led to efforts to improve selection. Nonorganic (Waddell) signs have been shown to portend treatment failure for surgery and other therapies but have not been studied for minimally invasive interventions.
Preoperative Pressure Pain Threshold Is Associated With Postoperative Pain in Short-Stay Anorectal Surgery: A Prospective Observational Study
Luedi, Markus M. MD, MBA*; Schober, Patrick MD, PhD, MMedStat†; Hammoud, Bassam MD‡; Andereggen, Lukas MD§; Hoenemann, Christian MD¶; Doll, Dietrich MD
doi : 10.1213/ANE.0000000000005072
Anesthesia & Analgesia. 132(3):656-662, March 2021.
Postoperative pain management is key for patient satisfaction. Pressure pain threshold (PPT) has been studied in some surgical cohorts but has not been studied in relationship to acute postoperative pain in short-stay patients undergoing anorectal surgery. We hypothesized that preoperative finger PPT measurements can identify respective patients with higher postoperative pain. Aiming to understand the relationship with subjective postoperative pain perception, we tested the hypotheses that preoperative PPT is associated with postoperative Visual Analog Scale (VAS) pain scores and correlates with postoperative analgesic consumption in short-stay patients undergoing anorectal surgery.
Comparison of Chloroprocaine Versus Lidocaine With Epinephrine, Sodium Bicarbonate, and Fentanyl for Epidural Extension Anesthesia in Elective Cesarean Delivery: A Randomized, Triple-Blind, Noninferiority Study
Sharawi, Nadir MD, MSc, FRCA*; Bansal, Prannal MD*; Williams, Matthew MD*; Spencer, Horace MS†; Mhyre, Jill M. MD
doi : 10.1213/ANE.0000000000005141
Anesthesia & Analgesia. 132(3):666-675, March 2021.
For emergent intrapartum cesarean delivery (CD), the literature does not support the use of any particular local anesthetic solution to extend epidural analgesia to cesarean anesthesia. We hypothesized that 3% chloroprocaine (CP) would be noninferior to a mixture of 2% lidocaine, 150 µg of epinephrine, 2 mL of 8.4% bicarbonate, and 100 µg of fentanyl (LEBF) in terms of onset time to surgical anesthesia.
Racial Disparities in Failure to Rescue Following Unplanned Reoperation in Pediatric Surgery
Willer, Brittany L. MD; Mpody, Christian MD, PhD, MPH, MBA; Tobias, Joseph D. MD; Nafiu, Olubukola O. MD, FRCA, MS
doi : 10.1213/ANE.0000000000005329
Anesthesia & Analgesia. 132(3):679-685, March 2021.
Failure to rescue (FTR) and unplanned reoperation following an index surgical procedure are key indicators of the quality of surgical care. Given that differences in unplanned reoperation and FTR rates among racial groups may contribute to persistent disparities in postsurgical outcomes, we sought to determine whether racial differences exist in the risk of FTR among children who required unplanned reoperation following inpatient surgical procedures.
The Effect of the No Pain Labor & Delivery-Global Health Initiative on Cesarean Delivery and Neonatal Outcomes in China: An Interrupted Time-Series Analysis
Drzymalski, Dan M. MD*; Guo, Jun-Cai MD†; Qi, Xue-Qin MD‡; Tsen, Lawrence C. MD§; Sun, Yingyong MD?; Ouanes, Jean-Pierre P. DO¶; Xia, Yun MD, PhD#; Gao, Wei Dong MD, PhD¶; Ruthazer, Robin MPH**; Hu, Fengling BS (MD, PhD candidate)††; Hu, Ling-Qun MD, FASA
doi : 10.1213/ANE.0000000000004805
Anesthesia & Analgesia. 132(3):698-706, March 2021.
The proportion of live births by cesarean delivery (CD) in China is significant, with some, particularly rural, provinces reporting up to 62.5%. The No Pain Labor & Delivery-Global Health Initiative (NPLD-GHI) was established to improve obstetric and neonatal outcomes in China, including through a reduction of CD through educational efforts. The purpose of this study was to determine whether a reduction in CD at a rural Chinese hospital occurred after NPLD-GHI. We hypothesized that a reduction in CD trend would be observed.
Segmented Regression in an Interrupted Time Series Study Design
Schober, Patrick MD, PhD, MMedStat*; Vetter, Thomas R. MD, MPH
doi : 10.1213/ANE.0000000000005269
Anesthesia & Analgesia. 132(3):696-697, March 2021.
Heparin Anti-Xa Activity, a Readily Available Unique Test to Quantify Apixaban, Rivaroxaban, Fondaparinux, and Danaparoid Levels
Boissier, Elodie PharmD*; Senage, Thomas MD, PhD†,‡; Babuty, Antoine MD*,§; Gouin-Thibault, Isabelle MD, PhD?; Rozec, Bertrand MD, PhD¶,#; Roussel, Jean-Christian MD, PhD†; Sigaud, Marianne MD*,§; Ternisien, Catherine MD, PhD*,§; Trossaert, Marc MD, PhD*,§; Fouassier, Marc MD*,§; Lakhal, Karim MD
doi : 10.1213/ANE.0000000000005114
Anesthesia & Analgesia. 132(3):707-716, March 2021.
Despite their usefulness in perioperative and acute care settings, factor-Xa inhibitor-specific assays are scarcely available, contrary to heparin anti-Xa assay. We assessed whether the heparin anti-Xa assay can (1) be used as a screening test to rule out apixaban, rivaroxaban, fondaparinux, and danaparoid levels that contraindicate invasive procedures according to current guidelines (>30 ng·mL?1, >30 ng·mL?1, >0.1 µg·mL?1, and >0.1 IU·mL?1, respectively), (2) quantify the anticoagulant level if found significant, that is, if it exceeded the abovementioned threshold.
Preoperative Point-of-Care Assessment of Left Ventricular Systolic Dysfunction With Transthoracic Echocardiography
Stenberg, Ylva MD*; Wallinder, Lina MD*; Lindberg, Anne MD, PhD†; Walldén, Jakob MD, PhD‡; Hultin, Magnus MD, PhD§; Myrberg, Tomi MD, PhD
doi : 10.1213/ANE.0000000000005263
Anesthesia & Analgesia. 132(3):717-725, March 2021.
Left ventricular (LV) systolic dysfunction is an acknowledged perioperative risk factor and should be identified before surgery. Conventional echocardiographic assessment of LV ejection fraction (LVEF) obtained by biplane LV volumes is the gold standard to detect LV systolic dysfunction. However, this modality needs extensive training and is time consuming. Hence, a feasible point-of-care screening method for this purpose is warranted. The aim of this study was to evaluate 3 point-of-care echocardiographic methods for identification of LV systolic dysfunction in comparison with biplane LVEF.
Predicting Unacceptable Pain in Cardiac Surgery Patients Receiving Morphine Maintenance and Rescue Doses: A Model-Based Pharmacokinetic-Pharmacodynamic Analysis
Goulooze, Sebastiaan C. MSc*; Krekels, Elke H. PhD*; Saleh, Mohammed A. MSc*; Ahlers, Sabine J. PhD, PharmD†; V?litalo, Pyry A. PhD‡,§; van Dongen, Eric P. MD, PhD?; van Schaik, Ron H. PhD¶; Hankemeier, Thomas PhD*; Tibboel, Dick MD, PhD#; Knibbe, Catherijne A. J. PharmD, PhD
doi : 10.1213/ANE.0000000000005228
Anesthesia & Analgesia. 132(3):726-734, March 2021.
Optimal analgesic treatment following cardiac surgery is crucial for both patient comfort and successful postoperative recovery. While knowledge of both the pharmacokinetics and pharmacodynamics of analgesics is required to predict optimal drug dosing, models quantifying the pharmacodynamics are scarce. Here, we quantify the pharmacodynamics of morphine by modeling the need for rescue morphine to treat unacceptable pain in 118 patients after cardiac surgery.
Relationship Between Propofol Target Concentrations, Bispectral Index, and Patient Covariates During Anesthesia
Schnider, Thomas W. Prof Dr med*; Minto, Charles F. MB, ChB, PhD†; Egan, Talmage D. MD‡; Filipovic, Miodrag Prof Dr med*
doi : 10.1213/ANE.0000000000005125
Anesthesia & Analgesia. 132(3):735-742, March 2021.
Internationally, propofol is commonly titrated by target-controlled infusion (TCI) to maintain a processed electroencephalographic (EEG) parameter (eg, bispectral index [BIS]) within a specified range. The overall variability in propofol target effect-site concentrations (CeT) necessary to maintain adequate anesthesia in real-world conditions is poorly characterized, as are the patient demographic factors that contribute to this variability. This study explored these issues, hypothesizing that the variability in covariate-adjusted propofol target concentrations during BIS-controlled anesthesia would be substantial and that most of the remaining interpatient variability in drug response would be due to random effects, thus suggesting that the opportunity to improve on the Schnider model with further demographic data is limited.
High-Flow Nasal Cannula Oxygen in Patients Having Anesthesia for Advanced Esophagogastroduodenoscopy: HIFLOW-ENDO, a Randomized Clinical Trial
Mazzeffi, Michael A. MD, MPH, MSc*; Petrick, Kendra M. BS, RN*; Magder, Laurence PhD†; Greenwald, Bruce D. MD‡; Darwin, Peter MD‡; Goldberg, Eric M. MD‡; Bigeleisen, Paul MD*; Chow, Jonathan H. MD*; Anders, Megan MD, MSc*; Boyd, Cynthia M. MD*; Kaplowitz, Jeremy S. MD*; Sun, Kai MS†; Terrin, Michael MDCM, MPH†; Rock, Peter MD, MBA
doi : 10.1213/ANE.0000000000004837
Anesthesia & Analgesia. 132(3):743-751, March 2021.
Over 6 million esophagogastroduodenoscopy (EGD) procedures are performed in the United States each year. Patients having anesthesia for advanced EGD procedures, such as interventional procedures, are at high risk for hypoxemia.
Effects of State Law Limiting Postoperative Opioid Prescription in Patients After Cesarean Delivery
Potnuru, Paul P. MD*; Patel, Selina D. MBBS, FRCA†; Birnbach, David J. MD, MPH†; Epstein, Richard H. MD, FASA†; Dudaryk, Roman MD
doi : 10.1213/ANE.0000000000004993
Anesthesia & Analgesia. 132(3):752-760, March 2021.
The impact of the Florida State law House Bill 21 (HB 21) restricting the duration of opioid prescriptions for acute pain in patients after cesarean delivery is unknown. Our objective was to assess the association of the passage of Florida State law HB 21 with trends in discharge opioid prescription practices following cesarean delivery, necessity for additional opioid prescriptions, and emergency department visits at a large tertiary care center.
Critical Care Medicine Practice: A Pilot Survey of US Anesthesia Critical Care Medicine–Trained Physicians
Siddiqui, Shahla MD, DABA, MSc, FCCM*; Bartels, Karsten MD, PhD†; Schaefer, Maximilian S. MD*,‡,§; Novack, Lena PhD*,‡,?; Sreedharan, Roshni MD¶; Ben-Jacob, Talia K. MD, MSc#,**; Khanna, Ashish K. MD, FCCP, FCCM††,‡‡,§§; Nunnally, Mark E. MD??; Souter, Michael MB ChB, DA, FRCA, FNCS¶¶; Simmons, Shawn T. MD##; Williams, George MD, FASA, FCCM, FCCP
doi : 10.1213/ANE.0000000000005030
Anesthesia & Analgesia. 132(3):761-769, March 2021.
This survey assessed satisfaction with the practice environment among physicians who have completed fellowship training in critical care medicine (CCM) as recognized by the American Board of Anesthesiology (and are members of the American Society of Anesthesiology) and evaluated the perceived effectiveness of training programs in preparing fellows for critical care practice.
Oxygen Reserve Index: Utility as an Early Warning for Desaturation in High-Risk Surgical Patients
Fleming, Neal W. MD, PhD; Singh, Amrik MD; Lee, Leonard MD; Applegate, Richard L. II MD
doi : 10.1213/ANE.0000000000005109
Anesthesia & Analgesia. 132(3):770-776, March 2021.
Perioperative pulse oximetry hemoglobin saturation (Spo2) measurement is associated with fewer desaturation and hypoxia episodes. However, the sigmoidal nature of oxygen–hemoglobin dissociation limits the accuracy of estimation of the partial pressure of oxygen (Pao2) >80 mm Hg and correspondingly limits the ability to identify when Pao2 >80 mm Hg but falling. We hypothesized that a proxy measurement for oxygen saturation (Oxygen Reserve Index [ORI]) derived from multiwavelength pulse oximetry may allow additional warning time before critical desaturation or hypoxia. To test our hypothesis, we used a Masimo multiwavelength pulse oximeter to compare ORI and Spo2 warning times during apnea in high-risk surgical patients undergoing cardiac surgery.
Clinical Outcomes of Pregnant and Postpartum Extracorporeal Membrane Oxygenation Patients
Lankford, Allison S. MD*; Chow, Jonathan H. MD†; Jackson, Amanda M. MD‡; Wallis, Marianne MD§; Galvagno, Samuel M. Jr DO, PhD, FCCM†; Malinow, Andrew M. MD†; Turan, Ozhan M. MD*; Menaker, Jay A. MD?; Crimmins, Sarah D. DO*; Rector, Raymond CCP¶; Kaczorowski, David MD?; Griffith, Bartley MD?; Kon, Zachary MD#; Herr, Daniel MD?; Mazzeffi, Michael A. MD, MPH, MSc
doi : 10.1213/ANE.0000000000005266
Anesthesia & Analgesia. 132(3):777-787, March 2021.
The use of extracorporeal membrane oxygenation (ECMO) as a rescue therapy for cardiopulmonary failure is expanding in critical care medicine. In this case series, we describe the clinical outcomes of 21 consecutive pregnant or postpartum patients that required venovenous (VV) or venoarterial (VA) ECMO. Our objective was to characterize maternal and fetal survival in peripartum ECMO and better understand ECMO-related complications that occur in this unique patient population.
In Pursuit of an Opioid-Free Pediatric Ambulatory Surgery Center: A Quality Improvement Initiative
Franz, Amber M. MD, MEng; Martin, Lynn D. MD, MBA; Liston, David E. MD, MPH; Latham, Gregory J. MD; Richards, Michael J. BM; Low, Daniel K. BM, BS
doi : 10.1213/ANE.0000000000004774
Anesthesia & Analgesia. 132(3):788-797, March 2021.
Opioids have been a central component of routine adult and pediatric anesthesia for decades. However, the long-term effects of perioperative opioids are concerning. Recent studies show a 4.8%–6.5% incidence of persistent opioid use after surgery in older children and adults. This means that >2 million of the 50 million patients undergoing elective surgeries in the United States each year are likely to develop persistent opioid use. With this in mind, anesthesiologists at Bellevue Clinic and Surgery Center assembled an interdisciplinary quality improvement team focused on 2 goals: (1) develop effective anesthesia protocols that minimize perioperative opioids and (2) add value to clinical services by maintaining or improving perioperative outcomes while reducing costs. This article describes our project and findings but does not attempt to make inferences or generalizations about populations outside our facility.
Pediatric Distraction on Induction of Anesthesia With Virtual Reality and Perioperative Anxiolysis: A Randomized Controlled Trial
Jung, Michael J. MD, MBA*; Libaw, Justin S. MD*,†; Ma, Kevin MD*; Whitlock, Elizabeth L. MD, MS*; Feiner, John R. MD*; Sinskey, Jina L. MD
doi : 10.1213/ANE.0000000000005004
Anesthesia & Analgesia. 132(3):798-806, March 2021.
Perioperative pediatric anxiety is common and can have a negative psychological impact on children undergoing surgery and anesthesia. Studies have shown an incidence of anxiety at induction of up to 50%. Audiovisual distraction, including virtual reality (VR), is a noninvasive, nonpharmacological modality that may reduce perioperative anxiety. The goal of this study was to determine whether immersive audiovisual distraction with a VR headset during induction of general anesthesia (GA) in pediatric patients reduced preoperative anxiety.
The Pediatric-Specific American Society of Anesthesiologists Physical Status Score: A Multicenter Study
Ferrari, Lynne MD*,†; Leahy, Izabela RN, BSN, MS*; Staffa, Steven J. MS*; Berry, Jay G. MD, MPH
doi : 10.1213/ANE.0000000000005025
Anesthesia & Analgesia. 132(3):807-817, March 2021.
When applied to the pediatric population, the American Society of Anesthesiologists physical status (ASA-PS) classification has exhibited poor reliability due to its subjective and adult-focused definitions. This study was done to measure interrater agreement of a pediatric-adapted ASA-PS classification and to solicit multicenter perspectives to optimize the pediatric ASA-PS classification.
Head Rotation Reduces Oropharyngeal Leak Pressure of the i-gel and LMA® Supreme™ in Paralyzed, Anesthetized Patients: A Randomized Trial
Chaki, Tomohiro MD, PhD*; Tachibana, Shunsuke MD, PhD*,†; Kumita, Sho MD*; Sato, Honami MD*; Hamada, Kosuke MD*; Tokinaga, Yasuyuki MD, PhD*; Yamakage, Michiaki MD, PhD
doi : 10.1213/ANE.0000000000005150
Anesthesia & Analgesia. 132(3):818-826, March 2021.
Second-generation supraglottic airway (SGA) devices are useful for airway management during positive pressure ventilation in general anesthesia and emergency medicine. In some clinical settings, such as the anesthetic management of awake craniotomy, SGAs are used in the head-rotated position, which is required for exposure of the surgical field, although this position sometimes worsens the efficiency of mechanical ventilation with SGAs. In this study, we investigated and compared the influence of head rotation on oropharyngeal leak pressures (OPLP) of the i-gel and LMA® Supreme™, which are second-generation SGA devices.
A Comparison of the Required Bronchial Cuff Volume Obtained by 2 Cuff Inflation Methods, Capnogram Waveform-Guided Versus Pressure-Guided: A Prospective Randomized Controlled Study
Yamada, Yuko MD*; Tanabe, Kumiko MD, PhD*; Nagase, Kiyoshi MD, PhD*; Ishihara, Takuma MSc†; Iida, Hiroki MD, PhD
doi : 10.1213/ANE.0000000000005179
Anesthesia & Analgesia. 132(3):827-835, March 2021.
Double-lumen endobronchial tubes (DLTs) are used for one-lung ventilation (OLV) during thoracic surgery. Overinflation into the bronchial cuff causes damage to the tracheobronchial mucosa, whereas underinflation leads to an incomplete collapse of the nonventilated lung or incomplete ventilation of the ventilated lung. However, how to determine the appropriate bronchial cuff volume and pressure during OLV is unclear. The objective of this study is to compare the required bronchial cuff volume for lung separation obtained by 2 different cuff inflation methods under closed- and open-chest conditions.
The Prevalence and Clinical Significance of Preoperative Thrombocytopenia in Adults Undergoing Elective Surgery: An Observational Cohort Study
Matzek, Luke J. MD*; Hanson, Andrew C. BS†; Schulte, Phillip J. PhD†; Evans, Kimberly D. RRT†; Kor, Daryl J. MD*,‡; Warner, Matthew A. MD
doi : 10.1213/ANE.0000000000005347
Anesthesia & Analgesia. 132(3):836-845, March 2021.
Preoperative thrombocytopenia is associated with inferior outcomes in surgical patients, though concurrent anemia may obfuscate these relationships. This investigation assesses the prevalence and clinical significance of preoperative thrombocytopenia with thorough consideration of preoperative anemia status.
Association Among Preoperative Cognitive Performance, Regional Cerebral Oxygen Saturation, and Postoperative Delirium in Older Portuguese Patients
Susano, Maria J. MD*,†; Dias, Mariana MD‡; Seixas, Francisco S. MD§; Vide, Sérgio MD, PhD*,?; Grasfield, Rachel BA¶; Abelha, Fernando J. MD, PhD#,**; Crosby, Gregory MD††; Culley, Deborah J. MD††; Amorim, Pedro MD
doi : 10.1213/ANE.0000000000005159
Anesthesia & Analgesia. 132(3):846-855, March 2021.
Postoperative delirium is common among older patients and preoperative identification of high-risk patients is widely recommended. The aim of this study was to assess whether preoperative cognitive performance using brief screening tools or regional cerebral oxygen saturation (Scto2) was associated with the development of postoperative delirium in older Portuguese patients undergoing elective surgery.
Elevated Plasma Concentrations of Syndecan-1 Do Not Correlate With Increased Capillary Leakage of 20% Albumin
Hahn, Robert G. MD, PhD*,†; Zdolsek, Markus MD‡; Krizhanovskii, Camilla PhD*,§; Ntika, Stelia*,§; Zdolsek, Joachim MD, PhD
doi : 10.1213/ANE.0000000000005315
Anesthesia & Analgesia. 132(3):856-865, March 2021.
Preclinical experiments show that an inflammatory reaction causes degradation of the endothelial glycocalyx layer and accelerated capillary leakage of albumin and fluid. The hypothesis in the present study was that elevated plasma concentrations of glycocalyx degradation products are associated with greater capillary leakage in humans.
Do It Often, Do It Better: Association Between Pairs of Experienced Subspecialty Anesthesia Caregivers and Postoperative Outcomes. A Retrospective Observational Study
Saager, Leif Dr med, MMM*,†; Ruetzler, Kurt MD, FAHA*,‡; Turan, Alparslan MD*,‡; Maheshwari, Kamal MD, MPH*,‡; Cohen, Barak MD*,§; You, Jing MS*,?; Mascha, Edward J. PhD*,?; Qiu, Yuwei MD*,¶; Ince, Ilker MD*,#; Sessler, Daniel I. MD
doi : 10.1213/ANE.0000000000005318
Anesthesia & Analgesia. 132(3):866-877, March 2021.
Anesthesiologists typically care for patients having a broad range of procedures. Outcomes might be improved when care is provided by caregivers experienced in particular types of surgery. We tested the hypothesis that intraoperative care provided by pairs of anesthesia caregivers having significant experience with a particular type of surgery reduces a composite of in-hospital death and 6 serious complications, including bleeding, cardiac, gastrointestinal, infectious, respiratory, and urinary complications, compared to care provided by pairs of anesthesia caregivers with less experience.
Dexmedetomidine and Clonidine Attenuate Sevoflurane-Induced Tau Phosphorylation and Cognitive Impairment in Young Mice via ?-2 Adrenergic Receptor
Sun, Mingyang MD, PhD*,†; Dong, Yuanlin MD, MS†; Li, Mengzhu MD, PhD†,‡; Zhang, Yiying MD, PhD†; Liang, Feng MD, PhD†; Zhang, Jiaqiang MD, PhD*; Soriano, Sulpicio G. MD§; Xie, Zhongcong MD, PhD
doi : 10.1213/ANE.0000000000005268
Anesthesia & Analgesia. 132(3):878-889, March 2021.
Anesthetic sevoflurane induces tau phosphorylation and cognitive impairment in young mice. The underlying mechanism and the targeted interventions remain largely unexplored. We hypothesized that dexmedetomidine and clonidine attenuated sevoflurane-induced tau phosphorylation and cognitive impairment by acting on ?-2 adrenergic receptor.
The Origins, Evolution, and Spread of Anesthesia Monitoring Standards: From Boston to Across the World
Pandya, Aniket N. BS; Majid, Sana Z. BS; Desai, Manisha S. MD
doi : 10.1213/ANE.0000000000005021
Anesthesia & Analgesia. 132(3):890-898, March 2021.
In the mid-1980s, the anesthesia departments at hospitals affiliated with Harvard Medical School were faced with a challenge: mounting medical malpractice costs. Malpractice insurance was provided by the Controlled Risk Insurance Company (CRICO), a patient safety and medical malpractice insurance company owned by and providing service to the Harvard medical community. CRICO spearheaded an effort to reduce these costs and ultimately found a way to decrease the risks associated with anesthesia. Here, we chronicle events that led to the dramatic changes in medical practice that resulted from the activities of a small group of concerned anesthesiologists at Harvard-affiliated hospitals. We place these events in a historical perspective and explore how other specialties followed this example, and end with current strategies that minimize the risk associated with anesthesia.
Fascial Plane Blocks: More Questions Than Answers?
Black, Nick D. MB BCh BAO, FRCA*; Stecco, Carla MD†; Chan, Vincent W. S. MD, FRCPC
doi : 10.1213/ANE.0000000000005321
Anesthesia & Analgesia. 132(3):899-905, March 2021.
Perioperative Lidocaine Infusion: Does the Risk Outweigh the Benefit?
Weinberg, Guy L. MD
doi : 10.1213/ANE.0000000000005322
Anesthesia & Analgesia. 132(3):906-909, March 2021.
Time Will Tell: Going Beyond Relative Value Units and American Society of Anesthesiologists Units to Objectively Quantify Nonclinical Contributions in Academic Medical Practice
Isaak, Robert S. DO, FASA; Kolarczyk, Lavinia M. MD, FASA; Blacker, Samuel MD, FASA; McNaull, Peggy P. MD; Arora, Harendra MD, MBA, FASA; Zvara, David A. MD, FASA
doi : 10.1213/ANE.0000000000005345
Anesthesia & Analgesia. 132(3):910-915, March 2021.
Drug Testing in Anesthesia: “Prevention and Protection” or “Major Risk for Minimal Gain”
Fitzsimons, Michael G.; Rice, Mark J.; Baker, Keith
doi : 10.1213/ANE.0000000000005350
Anesthesia & Analgesia. 132(3):916-919, March 2021.
Clinical Thoracic Anesthesia, 1st ed
Bryant, Brittany E.; Adler, Adam C.
doi : 10.1213/ANE.0000000000005326
Anesthesia & Analgesia. 132(3):e35, March 2021.
Echocardiography in ICU
Kim, Won Ho
doi : 10.1213/ANE.0000000000005331
Anesthesia & Analgesia. 132(3):e36, March 2021.
How to Change Your Mind: What the New Science of Psychedelics Teaches Us About Consciousness, Dying, Addiction, Depression, and Transcendence
Brindley, Peter G. MD, FRCPC, FRCP (Edin), FRCP (Lond)
doi : 10.1213/ANE.0000000000005349
Anesthesia & Analgesia. 132(3):e37-e38, March 2021.
Anaphylaxis: A Practical Guide, 1st ed
Brasher, Christopher MBBS, DTM&H, DA, FANZCA
doi : 10.1213/ANE.0000000000005357
Anesthesia & Analgesia. 132(3):e39, March 2021.
Epidural Technique in Obstetric Anesthesia
Kumar, Nishant
doi : 10.1213/ANE.0000000000005359
Anesthesia & Analgesia. 132(3):e40, March 2021.
Desflurane Should Not Des-appear
Answine, Joseph Frederick
doi : 10.1213/ANE.0000000000005319
Anesthesia & Analgesia. 132(3):e41-e42, March 2021.
The Need to Protect Health Care Workers Is Unchanged in the Presence of COVID-19 Pandemic Fatigue: The Probable Might Still Be Possible
Ip, Vivian H. Y.; Sondekoppam, Rakesh V.
doi : 10.1213/ANE.0000000000005337
Anesthesia & Analgesia. 132(3):e42-e43, March 2021.
In Response
Thiruvenkatarajan, Venkatesan MD, DA, DNB, FANZCA; Wong, David T. MD; Kothandan, Harikrishnan DNB, DA, FANZCA; Sekhar, Vimal MBBS, MClinSci; Adhikary, Sanjib Das MD; Currie, John MBChB, FFARCSI; Van Wijk, Roelof MD, PhD, FANZCA, FFPMANZCA
doi : 10.1213/ANE.0000000000005338
Anesthesia & Analgesia. 132(3):e43-e44, March 2021.
PRODIGY Score and Post-hoc Analysis of Previous Studies of Postoperative Respiratory Depression
Valencia Morales, Diana; Sprung, Juraj; Weingarten, Toby N.
doi : 10.1213/ANE.0000000000005339
Anesthesia & Analgesia. 132(3):e44-e45, March 2021.
In Response
Khanna, Ashish K.; Buhre, Wolfgang; Overdyk, Frank J.
doi : 10.1213/ANE.0000000000005340
Anesthesia & Analgesia. 132(3):e45-e46, March 2021.
Further Study Needed of the Impact of Early-Life Surgery With Associated General Anesthesia on the Risk of Attention Deficit Hyperactivity Disorder
Frisch, Morten; Earp, Brian D.; Van Howe, Robert S.
doi : 10.1213/ANE.0000000000005341
Anesthesia & Analgesia. 132(3):e46-e47, March 2021.
In Response
Ing, Caleb MD, MS; Wall, Melanie M. PhD; Olfson, Mark MD, MPH; Li, Guohua MD, DrPH
doi : 10.1213/ANE.0000000000005342
Anesthesia & Analgesia. 132(3):e47-e48, March 2021.
Integration of the Intrinsic Surgical Risk With Patient Comorbidities and Severity of Congenital Cardiac Disease Does Not Improve Risk Stratification in Children Undergoing Noncardiac Surgery
Hawkins, Jesse W.; Winch, Peter D.
doi : 10.1213/ANE.0000000000005360
Anesthesia & Analgesia. 132(3):e48-e49, March 2021.
Guest Reviewers
doi : 10.1213/ANE.0000000000005432
Anesthesia & Analgesia: March 2021 - Volume 132 - Issue 3 - p 920-926
