De Hert, Stefan
doi : 10.1097/EJA.0000000000001687
Volume 39(6) pgs. 487-570 June 2022
Merrer, Jade; Chantry, Anne A.; Blondel, Beatrice; Le Ray, Camille; Bonnet, Marie-Pierre
doi : 10.1097/EJA.0000000000001682
pg. 489-497
Disparities in access to pain management have been identified in several care settings, such as emergency departments and intensive care units, but with regard to labour analgesia, it remains poorly explored. OBJECTIVES: To determine the proportion of women without pain management during labour and its individual and organisational determinants.
Singh, Narinder Pal; Makkar, Jeetinder Kaur; Yadav, Neha; Goudra, Basavana Gouda; Singh, Preet Mohinder
doi : 10.1097/EJA.0000000000001626
pg. 498-510
Analgesic efficacy of intravenous dexamethasone has not been well defined after caesarean delivery. We performed a systematic review and meta-analysis to evaluate the impact of peri-operative dexamethasone administration on postoperative pain after caesarean delivery. OBJECTIVES: We investigated the impact of perioperative intravenous dexamethasone on postoperative pain after caesarean delivery. The two primary outcomes of interest were early (4 to 6 h) resting pain scores and time to first rescue analgesia.
Bleeser, Tom; Van Der Veeken, Lennart; Basurto, David; Valenzuela, Ignacio; Brenders, Arjen; Van Hoof, Lucas; Emam, Doaa; Vergote, Simen; Van de Velde, Marc; Devroe, Sarah; Deprest, Jan; Rex, Steffen
doi : 10.1097/EJA.0000000000001681
pg. 511-520
In pregnant women, anaesthesia-induced hypotension is commonly treated using phenylephrine or noradrenaline, the rationale being to maintain uterine perfusion pressure and thereby uterine blood flow. Evidence for this strategy during general anaesthesia for nonobstetric surgery is absent. OBJECTIVE: To analyse the effects of treating anaesthesia-induced hypotension with noradrenaline on brain development of rabbit foetuses of mothers subjected to general anaesthesia for nonobstetric surgery. We hypothesised that treatment of maternal hypotension would improve foetal outcomes.
Nummela, Aleksi J.; Laaksonen, Lauri T.; Laitio, Timo T.; Kallionpaa, Roosa E.; Langsjo, Jaakko W.; Scheinin, Joonas M.; Vahlberg, Tero J.; Koskela, Harri T.; Aittomaki, Viljami; Valli, Katja J.; Revonsuo, Antti; Niemi, Mikko; Perola, Markus; Scheinin, Harry
doi : 10.1097/EJA.0000000000001591
pg. 521-532
Pharmacometabolomics uses large-scale data capturing methods to uncover drug-induced shifts in the metabolic profile. The specific effects of anaesthetics on the human metabolome are largely unknown. OBJECTIVE: We aimed to discover whether exposure to routinely used anaesthetics have an acute effect on the human metabolic profile.
Dias, Priyanthi; Patel, Akshaykumar; Rook, William; Edwards, Mark R.; Pearse, Rupert M.; Abbott, Tom E.F.; SAPPHIRE Investigators
doi : 10.1097/EJA.0000000000001619
pg. 533-539
Antimicrobial prophylaxis is commonly used to prevent surgical site infection (SSI), despite concerns of overuse leading to antimicrobial resistance. However, it is unclear how often antimicrobials are used and whether guidelines are followed. OBJECTIVES: To describe contemporary clinical practice for antimicrobial prophylaxis including guideline compliance, the rate of postoperative infection and associated side effects.
Roger, Claire; Garrigue, Delphine; Bouhours, Guillaume; Dupont, Herve; Bouzat, Pierre; Bardon, Jean; Pottecher, Julien; Montravers, Philippe; Michelet, Pierre; Perbet, Sebastien; Aymart, Katia; Incagnoli, Pascal; Lloret, Sophie; Louart, Benjamin; Harrois, Anatole; for the ACUTE committee
doi : 10.1097/EJA.0000000000001683
pg. 540-548
Optimal management of community-acquired intra-abdominal infections (IAI) requires timely surgical source control and adequate anti-infective treatment. OBJECTIVE: To describe the initial management of community-acquired IAI admitted to the emergency department and assess the association between the length of time to either diagnosis or therapeutic procedures and patient outcomes.
Czarnetzki, Christoph; Albrecht, Eric; Desmeules, Jules; Kern, Christian; Corpataux, Jean-Baptiste; Gander, Sylvain; van Kuijk, Sander M.J.; Tramer, Martin R.
doi : 10.1097/EJA.0000000000001636
pg. 549-557
Dexamethasone is widely used for the prevention of postoperative nausea and vomiting (PONV) but little is known about its efficacy for the treatment of established PONV. OBJECTIVE: To test the antiemetic efficacy of intravenous dexamethasone for the treatment of established PONV in adults undergoing surgery under general anaesthesia and to determine whether there is dose-responsiveness.
Savoldelli, Georges L.; Ostergaard, Doris
doi : 10.1097/EJA.0000000000001667
pg. 558-561
Ashok, Vighnesh
doi : 10.1097/FJA.0000000000001645
pg. 561-562
Goffard, Philippe; Kapessidou, Yota
doi : 10.1097/EJA.0000000000001673
pg. 562-563
Cao, Huimin *; Jia, Lijie *; Guo, Yuna; Shen, Ying; Xu, Zifeng
doi : 10.1097/EJA.0000000000001569
pg. 563-566
Wild, Evan; You-Ten, Kong E.; Zasso, Fabricio; Downey, Kristi; Ye, Xiang Y.; Siddiqui, Naveed
doi : 10.1097/EJA.0000000000001564
pg. 566-568
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