دسترسی یکساله به بیش از ۵۰۰ ژورنال روز جهان موجود در سامانه
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Clinical Impact of Contralateral Carotid Occlusion in Patients Undergoing Carotid Artery Revascularization
Anna K.KrawiszMDabcKennethRosenfieldMDdeChristopher J.WhiteMDfgMichael R.JaffDObJosephCampbellMDeKevinKennedyMShThomasTsaiMDiBeauHawkinsMDjSchuylerJonesMDkEric A.SecemskyMDabc
doi : 10.1016/j.jacc.2020.12.032
Volume 77, Issue 7, 23 February 2021, Pages 835-844
The presence of a contralateral carotid occlusion (CCO) is an established high-risk feature for patients undergoing carotid endarterectomy (CEA) and is traditionally an indication for carotid artery stenting (CAS). Recent observational data have called into question whether CCO remains a high-risk feature for CEA.
Contralateral Carotid Artery Occlusion: Medical Therapy, Carotid Endarterectomy, Carotid Artery Stenting??
Gregory L.MonetaMD
doi : 10.1016/j.jacc.2021.01.002
Volume 77, Issue 7, 23 February 2021, Pages 845-847
Patient Characteristics and Clinical Outcomes of Type 1 Versus Type 2 Myocardial Infarction
Cian P.McCarthyMB, BCh, BAOaDhavalKolteMD, PhDaKevin F.KennedyMSbMuthiahVaduganathanMD, MPHcJason H.WasfyMD, MPhilaJames L.JanuzziJr.MDa
doi : 10.1016/j.jacc.2020.12.034
Volume 77, Issue 7, 23 February 2021, Pages 848-857
Type 2 myocardial infarction (MI) patients may have different characteristics and outcomes when compared with type 1 MI.
Adjusting the MI Codes Into the Framework of the Universal Definition of Myocardial Infarction?
KristianThygesenMD, DScaAllan S.JaffeMDb
doi : 10.1016/j.jacc.2021.01.003
Volume 77, Issue 7, 23 February 2021, Pages 858-860
Randomized Trial of Ivabradine in Patients With Hyperadrenergic Postural Orthostatic Tachycardia Syndrome
Pam R.TaubMDa?AdenaZadourianBSa?Hannah C.LoBSaCameron K.OrmistonBSaShahrokhGolshanPhDbJonathan C.HsuMD, MASa
doi : 10.1016/j.jacc.2020.12.029
Volume 77, Issue 7, 23 February 2021, Pages 861-871
Postural orthostatic tachycardia syndrome (POTS) is a complex, multifaceted disorder that impairs functional status and quality of life. Current pharmacological treatments are limited.
Higher Quality Evidence to Guide Our Management of Postural Orthostatic Tachycardia Syndrome: A New Era??
Satish R.RajMD, MSCIabRobert S.SheldonMD, PhDa
doi : 10.1016/j.jacc.2020.12.028
Volume 77, Issue 7, 23 February 2021, Pages 872-874
Pre-Diabetes Increases Stroke Risk in Patients With Nonvalvular Atrial Fibrillation
LouiseKezerleMDaMeytal AvgilTsadokPhDbAmichayAkrivMAbAdi BerlinerSendereyMPH, MScbAsafBachrachBScbMayaLeventer-RobertsMD, MPHcMotiHaimMDa
doi : 10.1016/j.jacc.2020.12.030
Volume 77, Issue 7, 23 February 2021, Pages 875-884
Diabetes mellitus (DM) increases the risk of embolism in nonvalvular atrial fibrillation (NVAF). The association between pre-diabetes and risk of ischemic stroke has not been studied separately in this population.
Pre-Diabetes and Stroke in Patients With Atrial Fibrillation: When Risk Begets Risk?
Emily P.ZeitlerMD, MHSabJonathan P.PicciniMD, MHSc
doi : 10.1016/j.jacc.2020.12.035
Volume 77, Issue 7, 23 February 2021, Pages 885-887
Subclinical Atherosclerosis and Brain Metabolism in Middle-Aged Individuals: The PESA Study
MartaCortes-CanteliPhDa?Juan DomingoGispertPhDbcde?GemmaSalvad?MScbcRaquelToribio-FernandezPhDaCatarinaTrist?o-PereiraMScaCarlesFalconPhDbdBelenOlivaMScaJoseMendigurenMDfLeticiaFernandez-FrieraMD, PhDaghJavierSanzMDaiJose M.Garcia-RuizMDahjAntonioFernandez-OrtizMD, PhDahkJavierSanchez-GonzalezPhDlBorjaIbanezMD, PhDahmJosé LuisMolinuevoMD, PhDbcen†ValentinFusterMD, PhDai†
doi : 10.1016/j.jacc.2020.12.027
Volume 77, Issue 7, 23 February 2021, Pages 888-898
Atherosclerosis has been linked to cognitive decline in late life; however, the impact of cardiovascular risk factors (CVRFs) and subclinical atherosclerosis on brain metabolism at earlier stages remains unexplored.
Midlife Cardiovascular Risk Factors, Subclinical Atherosclerosis, and Cerebral Hypometabolism?
Neal S.ParikhMD, MSaRebecca F.GottesmanMD, PhDb
doi : 10.1016/j.jacc.2020.12.046
Volume 77, Issue 7, 23 February 2021, Pages 899-901
Pathophysiology of Takotsubo Syndrome: JACC State-of-the-Art Review
Alexander R.LyonMD, PhDaRodolfoCitroMD, PhDbBirkeSchneiderMDcOlivierMorelMD, PhDdJelena R.GhadriMDeChristianTemplinMD, PhDeElmirOmerovicMD, PhDf
doi : 10.1016/j.jacc.2020.10.060
Volume 77, Issue 7, 23 February 2021, Pages 902-921
Takotsubo syndrome (TTS) has been a recognized clinical entity for 31 years, since its first description in 1990. TTS is now routinely diagnosed in patients who present with acute chest pain, electrocardiographic changes, troponin elevation, unobstructed coronary arteries, and a typical pattern of circumferential left ventricular wall motion abnormalities that usually involve the apical and midventricular myocardium. Increasing understanding of this intriguing syndrome stems from wider recognition, possible increasing frequency, and a rising number of publications focused on the pathophysiology in clinical and laboratory studies. A comprehensive understanding of TTS pathophysiology and evidence-based treatments are lacking, and specific and effective treatments are urgently required. This paper reviews the pathophysiology of this fascinating syndrome; what is known from both clinical and preclinical studies, including review of the evidence for microvascular dysfunction, myocardial beta-adrenergic signaling, inflammation, and electrophysiology; and where focused research needs to fill gaps in understanding TTS.
Cardiac Involvement in Fabry Disease: JACC Review Topic of the Week
MaurizioPieroniMD, PhDaJames C.MoonMDbEloisaArbustiniMDcRobertoBarriales-VillaMD, PhDdAntoniaCamporealeMD, PhDeAndreja CokanVujkovacMDfPerry M.ElliottMBBS, MDbAlbertHagegeMD, PhDgJohannaKuusistoMD, PhDhAle?LinhartMD, PhDiPeterNordbeckMDjIacopoOlivottoMDkP?iviPietil?-EffatiMDlMehdiNamdarMD, PhDm
doi : 10.1016/j.jacc.2020.12.024
Volume 77, Issue 7, 23 February 2021, Pages 922-936
Fabry disease (FD) is a rare X-linked inherited lysosomal storage disorder caused by deficient ?-galactosidase A activity that leads to an accumulation of globotriasylceramide (Gb3) in affected tissues, including the heart. Cardiovascular involvement usually manifests as left ventricular hypertrophy, myocardial fibrosis, heart failure, and arrhythmias, which limit quality of life and represent the most common causes of death. Following the introduction of enzyme replacement therapy, early diagnosis and treatment have become essential to slow disease progression and prevent major cardiac complications. Recent advances in the understanding of FD pathophysiology suggest that in addition to Gb3 accumulation, other mechanisms contribute to the development of Fabry cardiomyopathy. Progress in imaging techniques have improved diagnosis and staging of FD-related cardiac disease, suggesting a central role for myocardial inflammation and setting the stage for further research. In addition, with the recent approval of oral chaperone therapy and new treatment developments, the FD-specific treatment landscape is rapidly evolving.
Editor-in-Chief’s Top Picks From 2020
ValentinFusterMD, PhD
doi : 10.1016/j.jacc.2020.12.044
Volume 77, Issue 7, 23 February 2021, Pages 937-997
2021 ACC/AHA/SVM/ACP Advanced Training Statement on Vascular Medicine (Revision of the 2004 ACC/ACP/SCAI/SVMB/SVS Clinical Competence Statement on Vascular Medicine and Catheter-Based Peripheral Vascular Interventions): A Report of the ACC Competency Management Committee
Writing Committee MembersMark A.CreagerMD, FACC, FAHA, MSVM(Chair)Naomi M.HamburgMD, FACC, FAHA, FSVM(Vice Chair)Keith D.CalligaroMD?Ana I.CasanegraMD, MS, FSVM†RosarioFreemanMD, MS, FACCPhyllis A.GordonMSN, APRN(Retired)‡Heather L.GornikMD, FAHA, FSVM†Esther S.H.KimMD, MPH, FACC, FAHA, FSVM§Nicholas J.LeeperMD, FSVM§Geno J.MerliMD, FSVM, MACP||KhusrowNiaziMBBS, FACC, FSCAIJeffrey W.OlinDO, FACC, FAHA, MSVMReneQuirozMDElonaRrapo KasoMDSumanWasanMD, MS, FSVM†Andrew R.WaxlerMD, FACCChristopher J.WhiteMD, MACC, FAHA, FACP, MSCAI¶…Marlene S.WilliamsMD, FACC#
doi : 10.1016/j.jacc.2020.09.579
Volume 77, Issue 7, 23 February 2021, Pages 998-1020
Trends in Cardiovascular Medicine Use in 65 Middle- and High-Income Countries
Vincent K.C.YanBPharmJoseph E.BlaisBScPharmXueLiPhDCeline S.L.ChuiPhDLiWeiPhDBryan P.YanMBBSMartin R.J.KnappPhDChung WahSiuMDIan C.K.WongPhDEsther W.ChanPhD
doi : 10.1016/j.jacc.2020.12.025
Volume 77, Issue 7, 23 February 2021, Pages 1021-1023
Patients Hospitalized for De Novo Versus Worsening Chronic Heart Failure in the United States
Stephen J.GreeneMDTaylor S.TrianaMDRalucaIonescu-IttuMSc, PhDSherryShiMScAnnieGuérinMScMary M.DeSouzaMBA, PhDPaul D.KesslerMDAylinTugcuMDMariaBorentainMDG. MichaelFelkerMD, MHS
doi : 10.1016/j.jacc.2020.12.026
Volume 77, Issue 7, 23 February 2021, Pages 1023-1025
Effects of Omega-3 Fatty Acids on Ventricular Remodeling and Systemic Inflammation After Acute Myocardial Infarction
PanagiotisAntiochosMDYinGeMD
doi : 10.1016/j.jacc.2020.11.071
Volume 77, Issue 7, 23 February 2021, Page 1026
Reply: Effects of Omega-3 Fatty Acids on Ventricular Remodeling and Systemic Inflammation After Acute Myocardial Infarction
AntoniBayés-Gen?sMD, PhDElenaRevuelta-L?pezPhDAleixSala-VilaPharmD, PhD
doi : 10.1016/j.jacc.2020.12.023
Volume 77, Issue 7, 23 February 2021, Pages 1026-1028
