Muthiah Vaduganathan, MD, MPH,a, * Brian L. Claggett, P HD, a, * Pardeep Jhund, MD, PHD, b Rudolf A. de Boer, MD,c Adrian F. Hernandez, MD,d Silvio E. Inzucchi, MD,e Mikhail N. Kosiborod, MD,f Carolyn S.P. Lam, MD, g Felipe Martinez, MD, h Sanjiv J. Shah, MD, i Akshay S. Desai, MD, a Daniel Lindholm, MD, P HD, j Magnus Petersson, MD, PHD, j Anna Maria Langkilde, MD, j John J.V. McMurray, b Scott D. Solomon, MD
doi : 10.1016/j.jacc.2022.08.745
Volume 80, Issue 19, 8 November 2022, Pages 1775-1784
Recent guidelines support consideration of sodium-glucose cotransporter-2 inhibitors in the long-term management of heart failure (HF) with mildly reduced or preserved ejection fraction. Patients and clinicians may be interested in the expected lifetime benefits of sodium-glucose cotransporter-2 inhibitors in this population.
Michael E. Nassif, MD,a James L. Januzzi, J R , MD
doi : 10.1016/j.jacc.2022.09.008
Volume 80, Issue 19, 8 November 2022, Pages 1785-1787
Wei Gong, MD, PHD, a,b,c, * Yan Yan, MD, a,b,c, * Xiao Wang, MD,a,b,c Wen Zheng, MD,a,b,c Sidney C. Smith, J R , MD,d Gregg C. Fonarow, MD, e Louise Morgan, MSN,f Jing Liu, MD, PHD, g Dong Zhao, MD, PH D, g Changsheng Ma, MD,b,c,h Yaling Han, MD, PHD, i Gilles Montalescot, MD, PH D, j Shaoping Nie, MD, PHD, a,b,c on behalf of the CCC-ACS Investigators
doi : 10.1016/j.jacc.2022.08.797
Volume 80, Issue 19, 8 November 2022, Pages 1788-1798
In-hospital cardiac arrest (IHCA) is one of the most deleterious complications of ST-segment elevation myocardial infarction (STEMI).
Graham Nichol, MD, MPH,a,b,y Amanda West, MD, MPH
doi : 10.1016/j.jacc.2022.09.009
Volume 80, Issue 19, 8 November 2022, Pages 1799-1801
Barbara E. Stähli, MD, MPH, MBA, a, * Roland Klingenberg, MD, b, * Dik Heg, P HD, c Mattia Branca, PH D, c Robert Manka, MD, a,d Ioannis Kapos, MD,a Oliver Müggler, MD, a Andrea Denegri, MD, a Rahel Kesterke, PHD, a Florence Berger, PH D, a Julia Stehli, MD,a Alessandro Candreva, MD,a Arnold von Eckardstein, MD, e David Carballo, MD,f Christian Hamm, MD, b Ulf Landmesser, MD, g François Mach, MD,f Tiziano Moccetti, MD, h Christian Jung, MD,i Malte Kelm, MD, i Thomas Münzel, MD, j Giovanni Pedrazzini, MD,h Lorenz Räber, MD, P HD, k Stephan Windecker, MD,k Christian Templin, MD, PHD, a Christian M. Matter, MD, a Thomas F. Lüscher, MD,l,m,y Frank Ruschitzka, MD
doi : 10.1016/j.jacc.2022.08.747
Volume 80, Issue 19, 8 November 2022, Pages 1802-1814
Early inflammation following acute ST-segment elevation myocardial infarction (STEMI) treated by primary percutaneous coronary intervention (PCI) affects myocardial infarct (MI) size and left ventricular remodeling. The mammalian target of rapamycin (mTOR) is involved in the enhanced inflammatory response and its inhibition has exerted beneficial effects on MI size in preclinical models of acute MI.
Jean-Claude Tardif, MD, Eric Thorin, PHD
doi : 10.1016/j.jacc.2022.08.796
Volume 80, Issue 19, 8 November 2022, Pages 1815-1817
Massimiliano Camilli, MD,a,b, * Michele Russo, MD, P HD, a, * Riccardo Rinaldi, MD, a Andrea Caffè, MD,a Giulia La Vecchia, MD,a Alice Bonanni, BSC , PH D, a Giulia Iannaccone, MD, a Mattia Basile, MD,a Rocco Vergallo, MD, PH D, b Cristina Aurigemma, MD, PHD, b Carlo Trani, MD, a,b Giampaolo Niccoli, MD, PH D, c Filippo Crea, MD, a,b,y Rocco A. Montone, MD, PHD
doi : 10.1016/j.jacc.2022.08.744
Volume 80, Issue 19, 8 November 2022, Pages 1818-1828
Coronary vasomotor abnormalities are important causes of myocardial ischemia in patients with nonobstructive coronary artery disease (NOCAD). However, the role of air pollution in determining coronary vasomotor disorders has never been investigated.
Sanjay Rajagopalan, MD, a Jagat Narula, MD
doi : 10.1016/j.jacc.2022.09.015
Volume 80, Issue 19, 8 November 2022, Pages 1829-1832
Alistair Royse, MBBS, MD, a,b, * Justin Ren, BMEDS C,a, * Colin Royse, MBBS, MD,a,b,c David H. Tian, MD, PHD, d Stephen Fremes, MD, MS C, e Mario Gaudino, MD, PHD, f Umberto Benedetto, MD, P HD, g Y. Joseph Woo, MD,h Andrew B. Goldstone, MD, PH D, i Piroze Davierwala, MBBS, P HD, e,j Michael Borger, MD, PHD, j Michael Vallely, MBBS, PHD, k Christopher M. Reid, MSC , BA, PHD, l Rodolfo Rocha, MD, P HD, e David Glineur, MD, PH D, m,n Juan Grau, MD, P HD, m Richard Shaw, MD,o Hugh Paterson, MBBS, p Doa El-Ansary, BAPPSC (P HTY), PH D, a,q Stuart Boggett, BS CI, MC-BM EDS C,a Nilesh Srivastav, MBBS, a Zulfayandi Pawanis, MBBS, MB IOMEDS CI,r David Canty, MBBS, PHD, a Rinaldo Bellomo, MD, PH D
doi : 10.1016/j.jacc.2022.08.795
Volume 80, Issue 19, 8 November 2022, Pages 1833-1843
Approximately 95% of patients of any age undergoing contemporary, coronary bypass surgery will receive at least 1Â saphenous vein graft (SVG). It is recognized that SVG will develop progressive and accelerated atherosclerosis, resulting in a stenosis, and in occlusion that occurs in 50% by 10 years postoperatively.
Edward T.A. Fry, MD, FACC, President, American College of Cardiology Samuel O. Jones IV, MD, MPH, FACC, Chair, Health Affairs Committee Nick Morse, MBA, ACC Division Vice President, Advocacy
doi : 10.1016/j.jacc.2022.09.022
Volume 80, Issue 19, 8 November 2022, Pages 1844-1847
Valentin Fuster, MD, P HD, Editor-in-Chief, Journal of the American College of Cardiology, Justine Varieur Turco, MA, Divisional Vice President, American College of Cardiology
doi : 10.1016/j.jacc.2022.09.017
Volume 80, Issue 19, 8 November 2022, Pages 1848-1850
Samip Sheth, MB, a Adriana C. Mares, MS, b Gurleen Kaur, MD
doi : 10.1016/j.jacc.2022.08.788
Volume 80, Issue 19, 8 November 2022, Pages 1851-1854
Melvin R. Echols, MD
doi : 10.1016/j.jacc.2022.08.798
Volume 80, Issue 19, 8 November 2022, Page 1854
Sadeer Al-Kindi, MD Issam Motairek, MD Scott Janus, MD Salil Deo, MD Mahboob Rahman, MD Ian J. Neeland, MD Sanjay Rajagopalan, MD
doi : 10.1016/j.jacc.2022.08.791
Volume 80, Issue 19, 8 November 2022, Pages 1855-1856
Nicola Gaibazzi, MD, PhD Alberto Foà , MD Luca Bergamaschi, MD Domenico Tuttolomondo, MD Carmine Pizzi, MD
doi : 10.1016/j.jacc.2022.08.792
Volume 80, Issue 19, 8 November 2022, Page e167
*Wade H. Martin III, MD
doi : 10.1016/j.jacc.2022.08.794
Volume 80, Issue 19, 8 November 2022, Page e169
Alan Rozanski, MD Robert J.H. Miller, MD Donghee Han, MD Daniel S. Berman, MD
doi : 10.1016/j.jacc.2022.08.793
Volume 80, Issue 19, 8 November 2022, Pages e171-e172
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