Journal of Crohn's and Colitis




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سفارش

European Crohn’s and Colitis Guidelines on Sexuality, Fertility, Pregnancy, and Lactation

Joana Torres, María Chaparro, Mette Julsgaard, Konstantinos Katsanos, Zuzana Zelinkova, Manasi Agrawal, Sandro Ardizzone, Marjo Campmans-Kuijpers, Gabriele Dragoni, Marc Ferrante, Gionata Fiorino, Emma Flanagan, Catarina Frias Gomes, Ailsa Hart, Charlotte Rose Hedin, Pascal Juillerat, Annemarie Mulders, Pär Myrelid, Aoibhlinn O’Toole, Pauline Rivière, Michael Scharl, Christian Philipp Selinger, Elena Sonnenberg, Murat Toruner, Jantien Wieringa, C Janneke Van der Woude

doi : 10.1093/ecco-jcc/jjac115

Journal of Crohn's and Colitis, Volume 17, Issue 1, January 2023, Pages 1–27

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IBD Risk—It Is All in the Family!

Mohmmed Tauseef Sharip, Sreedhar Subramanian

doi : 10.1093/ecco-jcc/jjac118

Journal of Crohn's and Colitis, Volume 17, Issue 1, January 2023, Pages 28–29

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Risk Factors for Developing Inflammatory Bowel Disease Within and Across Families with a Family History of IBD

Joana Torres, Catarina Gomes, Camilla B Jensen, Manasi Agrawal, Francisco Ribeiro-Mourão, Tine Jess, Jean-Frédéric Colombel, Kristine H Allin, Johan Burisch

doi : 10.1093/ecco-jcc/jjac111

Journal of Crohn's and Colitis, Volume 17, Issue 1, January 2023, Pages 30–36

A family history of inflammatory bowel disease [IBD] is the strongest risk factor for disease. However, some first-degree relatives (FDRs) will develop disease, while others will not.

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The Impact of COVID-19 on Patients with IBD in a Prospective European Cohort Study

Aurelien Amiot, Jean-Francois Rahier, Filip Baert, Stephane Nahon, Ailsa Hart, Nikos Viazis, Livia Biancone, Eugeni Domenech, Catherine Reenears, Laurent Peyrin-Biroulet, Laurent Beaugerie, Johan Burisch, I-CARE collaborator group

doi : 10.1093/ecco-jcc/jjac091

Journal of Crohn's and Colitis, Volume 17, Issue 1, January 2023, Pages 37–48

There are concerns regarding the potential impact of the COVID-19 outbreak on patients with inflammatory bowel disease [IBD]. We report on the impact of the COVID-19 outbreak in a European prospective cohort study of patients with IBD

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Chromosomal Numerical Aberrations and Rare Copy Number Variation in Patients with Inflammatory Bowel Disease

Paulina Dirvanskyte, Bhaskar Gurram, Chrissy Bolton, Neil Warner, Kelsey D J Jones, Helen R Griffin, Genomics England Research Consortium, Jason Y Park, Klaus-Michael Keller, Kimberly C Gilmour, Sophie Hambleton, Aleixo M Muise, Christian Wysocki, Holm H Uhlig

doi : 10.1093/ecco-jcc/jjac103

Journal of Crohn's and Colitis, Volume 17, Issue 1, January 2023, Pages 49–60

Inflammatory bowel diseases [IBD] have a complex polygenic aetiology. Rare genetic variants can cause monogenic intestinal inflammation. The impact of chromosomal aberrations and large structural abnormalities on IBD susceptibility is not clear. We aimed to comprehensively characterise the phenotype and prevalence of patients with IBD who possess rare numerical and structural chromosomal abnormalities.

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Successful Dietary Therapy in Paediatric Crohn’s Disease is Associated with Shifts in Bacterial Dysbiosis and Inflammatory Metabotype Towards Healthy Controls

Charlotte M Verburgt, Katherine A Dunn, Mohammed Ghiboub, James D Lewis, Eytan Wine, Rotem Sigall Boneh, Konstantinos Gerasimidis, Raanan Shamir, Susanne Penny, Devanand M Pinto, Alejandro Cohen, Paul Bjorndahl, Vaios Svolos, Joseph P Bielawski, Marc A Benninga, Wouter J de Jonge, Johan E Van Limbergen

doi : 10.1093/ecco-jcc/jjac105

Journal of Crohn's and Colitis, Volume 17, Issue 1, January 2023, Pages 61–72

Nutritional therapy with the Crohn’s Disease Exclusion Diet + Partial Enteral Nutrition [CDED+PEN] or Exclusive Enteral Nutrition [EEN] induces remission and reduces inflammation in mild-to-moderate paediatric Crohn’s disease [CD]. We aimed to assess if reaching remission with nutritional therapy is mediated by correcting compositional or functional dysbiosis.

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Risk Prediction for Complications in Inflammatory Bowel Disease Surgery: External Validation of the American College of Surgeons’ National Surgical Quality Improvement Program Surgical Risk Calculator

Viviane Lin, Seyma Gögenur, Frederik Pachler, Tina Fransgaard, Ismail Gögenur

doi : 10.1093/ecco-jcc/jjac114

Journal of Crohn's and Colitis, Volume 17, Issue 1, January 2023, Pages 73–82

Many patients with inflammatory bowel disease [IBD] require surgery during their disease course. Having individual risk predictions available prior to surgery could aid in better informed decision making for personalised treatment trajectories in IBD surgery.

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Effectiveness and Safety of Ustekinumab in Elderly Patients with Crohn’s Disease: Real World Evidence From the ENEIDA Registry

Diego Casas-Deza, Luis Javier Lamuela-Calvo, Fernando Gomollón, José Miguel Arbonés-Mainar, Berta Caballol, Javier P Gisbert, Montserrat Rivero, Eugenia Sánchez-Rodríguez, Lara Arias García, Ana Gutiérrez Casbas, Olga Merino, Lucía Márquez, Viviana Laredo, María Dolores Martín-Arranz, Pilar López Serrano, Sabino Riestra Menéndez, Carlos González-Muñoza, Luisa de Castro Parga, Marta Calvo Moya, Esteban Fuentes-Valenzuela, Maria Esteve, Marisa Iborra, Miguel Dura Gil, Manuel Barreiro-De Acosta, Rufo Humberto Lorente-Poyatos, Noemí Manceñido, Margalida Calafat, Iago Rodríguez-Lago, Jordi Guardiola Capo, Maria Antonia Payeras, Víctor Jair Morales Alvarado, Carlos Tardillo, Luis Bujanda, José Fernando Muñoz-Nuñez, Yolanda Ber Nieto, Fernando Bermejo, Pedro Almela, Mercè Navarro-Llavat, Pilar Martínez Montiel, Cristina Rodríguez Gutiérrez, Manuel Van Domselaar, Eva Sesé, Teresa Martínez Pérez, Elena Ricart, María Chaparro, María José García, Antonio López-Sanromán, Beatriz Sicilia, Beatriz Orts, Alicia López-García, Eduardo Martín-Arranz, José Lázaro Pérez-Calle, Ruth de Francisco, Esther García-Planella, Eugeni Domènech, y Santiago García-López on behalf of the ENEIDA Registry by GETECCU

doi : 10.1093/ecco-jcc/jjac108

Journal of Crohn's and Colitis, Volume 17, Issue 1, January 2023, Pages 83–91

Clinical trials and real-life studies with ustekinumab in Crohn’s disease [CD] have revealed a good efficacy and safety profile. However, these data are scarcely available in elderly patients. Therefore, we aim to assess the effectiveness and safety of ustekinumab in elderly patients with CD.

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Proteomic Analysis Identifies Three Reliable Biomarkers of Intestinal Inflammation in the Stools of Patients With Inflammatory Bowel Disease

Roberta Vitali, Francesca Palone, Alessandro Armuzzi, Valerio Fulci, Anna Negroni, Claudia Carissimi, Salvatore Cucchiara, Laura Stronati

doi : 10.1093/ecco-jcc/jjac110

Journal of Crohn's and Colitis, Volume 17, Issue 1, January 2023, Pages 92–102,

Faecal biomarkers have emerged as important tools in managing of inflammatory bowel disease [IBD], which includes Crohn’s disease [CD] and ulcerative colitis [UC].

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Venous Thromboembolism Following Discharge from Hospital in Patients Admitted for Inflammatory Bowel Disease

Philip R Harvey, Benjamin Coupland, Jemma Mytton, Shanika De Silva, Nigel J Trudgill

doi : 10.1093/ecco-jcc/jjac112

Journal of Crohn's and Colitis, Volume 17, Issue 1, January 2023, Pages 103–110

Patients admitted to hospital with inflammatory bowel disease[IBD] are at increased risk of venous thromboembolism[VTE]. This study aims to identify IBD patients at increased VTE risk on hospital discharge and to develop a risk scoring system to recognise them.

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A Protective Role of NOD2 on Oxazolone-induced Intestinal Inflammation Through IL-1β-mediated Signalling Pathway

Thomas Secher, Aurélie Couturier, Ludovic Huot, Helene Bouscayrol, Teddy Grandjean, Olivier Boulard, David Hot, Bernhard Ryffel, Mathias Chamaillard

doi : 10.1093/ecco-jcc/jjac106

Journal of Crohn's and Colitis, Volume 17, Issue 1, January 2023, Pages 111–122

NOD2 has emerged as a critical player in the induction of both Th1 and Th2 responses for potentiation and polarisation of antigen-dependent immunity.

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Placebo Rates in Randomized Controlled Trials of Proctitis Therapy: A Systematic Review and Meta-Analysis Placebo Response in Proctitis

Theshani A De Silva, Lotus Alphonsus, Christopher Ma, Malcolm Hogan, Rocio Sedano, Neeraj Narula, Silvio Danese, Laurent Peyrin-Biroulet, John K MacDonald, Siddharth Singh, Vipul Jairath

doi : 10.1093/ecco-jcc/jjac109

Journal of Crohn's and Colitis, Volume 17, Issue 1, January 2023, Pages 123–136

Treatment options for proctitis are limited. To assist trial design for novel therapeutics, we conducted a systematic review and meta-analysis of proctitis randomized controlled trials [RCTs] to quantify placebo rates and identify factors influencing them.

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Available Methods for Benefit-risk Assessment: Lessons for Inflammatory Bowel Disease Drugs

Bénédicte Caron, Ferdinando D’Amico, Vipul Jairath, Patrick Netter, Silvio Danese, Laurent Peyrin-Biroulet

doi : 10.1093/ecco-jcc/jjac113

Journal of Crohn's and Colitis, Volume 17, Issue 1, January 2023, Pages 137–143

Medical treatment for inflammatory bowel disease has advanced significantly over the two past decades. The advent of biologics and small molecules has revolutionised outcomes for patients with inflammatory bowel disease.

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Ustekinumab-Induced Inflammatory Demyelinating Polyneuropathy in a Patient with Ulcerative Colitis

Sailish Honap, Peter M Irving, Mark A Samaan

doi : 10.1093/ecco-jcc/jjac116

Journal of Crohn's and Colitis, Volume 17, Issue 1, January 2023, Pages 144–145

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Evaluating Discriminative Accuracy of Biomarkers in Relation to Binary Study Outcomes: First Validate, Then Celebrate?

Arno R Bourgonje

doi : 10.1093/ecco-jcc/jjac117

Journal of Crohn's and Colitis, Volume 17, Issue 1, January 2023, Page 146

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Response to: Evaluating Discriminative Accuracy of Biomarkers in Relation to Binary Study Outcomes: First Validate, Then Celebrate?

Akhilesh Swaminathan, Chris M Frampton, Grace M Borichevsky, Anthony J Kettle, Richard B Gearry

doi : 10.1093/ecco-jcc/jjac126

Journal of Crohn's and Colitis, Volume 17, Issue 1, January 2023, Pages 147–148

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Correction

doi : 10.1093/ecco-jcc/jjac104

Journal of Crohn's and Colitis, Volume 17, Issue 1, January 2023, Page 149

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Corrigendum to: P169 Vitamin D levels are inversely associated with inflammation in pediatric Inflammatory Bowel Disease patients

doi : 10.1093/ecco-jcc/jjac107

Journal of Crohn's and Colitis, Volume 17, Issue 1, January 2023, Page 150

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