دسترسی یکساله به بیش از ۵۰۰ ژورنال روز جهان موجود در سامانه
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Urgent Need for Studies of the Late Effects of SARS-CoV-2 on the Cardiovascular System
Joseph J. Maleszewski, Phillip M. Young, Michael J. Ackerman, Marc K. Halushka
doi : 10.1161/CIRCULATIONAHA.120.051362
Circulation. 2021 | Volume 143, Issue 13: 1271–1273
Artificial Intelligence–Enabled Assessment of the Heart Rate Corrected QT Interval Using a Mobile Electrocardiogram Device
John R. Giudicessi, Matthew Schram, J. Martijn Bos, Conner D. Galloway, Jacqueline B. Shreibati, Patrick W. Johnson, Rickey E. Carter, Levi W. Disrud, Robert Kleiman, Zachi I. Attia, Peter A. Noseworthy, Paul A. Friedman, David E. Albert, Michael J. Ackerman
doi : 10.1161/CIRCULATIONAHA.120.050231
Circulation. 2021 | Volume 143, Issue 13: 1274–1286
Heart rate–corrected QT interval (QTc) prolongation, whether secondary to drugs, genetics including congenital long QT syndrome, and/or systemic diseases including SARS-CoV-2–mediated coronavirus disease 2019 (COVID-19), can predispose to ventricular arrhythmias and sudden cardiac death. Currently, QTc assessment and monitoring relies largely on 12-lead electrocardiography. As such, we sought to train and validate an artificial intelligence (AI)–enabled 12-lead ECG algorithm to determine the QTc, and then prospectively test this algorithm on tracings acquired from a mobile ECG (mECG) device in a population enriched for repolarization abnormalities.
Deep Neural Networks Can Predict New-Onset Atrial Fibrillation From the 12-Lead ECG and Help Identify Those at Risk of Atrial Fibrillation–Related Stroke
Sushravya Raghunath, John M. Pfeifer, Alvaro E. Ulloa-Cerna, Arun Nemani, Tanner Carbonati, Linyuan Jing, David P. vanMaanen, Dustin N. Hartzel, Jeffery A. Ruhl, Braxton F. Lagerman, Daniel B. Rocha, Nathan J. Stoudt, Gargi Schneider, Kipp W. Johnson, Noah Zimmerman, Joseph B. Leader, H. Lester Kirchner, Christoph J. Griessenauer, Ashraf Hafez, Christopher W. Good, Brandon K. Fornwalt, Christopher M. Haggerty
doi : 10.1161/CIRCULATIONAHA.120.047829
Circulation. 2021 | Volume 143, Issue 13: 1287–1298
Atrial fibrillation (AF) is associated with substantial morbidity, especially when it goes undetected. If new-onset AF could be predicted, targeted screening could be used to find it early. We hypothesized that a deep neural network could predict new-onset AF from the resting 12-lead ECG and that this prediction may help identify those at risk of AF-related stroke.
Trusting Magic
Michael A. Rosenberg
doi : 10.1161/CIRCULATIONAHA.121.053733
Circulation. 2021 | Volume 143, Issue 13: 1299–1301
Genetic Variation in Enhancers Modifies Cardiomyopathy Gene Expression and Progression
Anthony M. Gacita, Dominic E. Fullenkamp, Joyce Ohiri, Tess Pottinger, Megan J. Puckelwartz, Marcelo A. Nobrega, Elizabeth M. McNally
doi : 10.1161/CIRCULATIONAHA.120.050432
Circulation. 2021 | Volume 143, Issue 13: 1302–1316
Inherited cardiomyopathy associates with a range of phenotypes, mediated by genetic and nongenetic factors. Noninherited cardiomyopathy also displays varying progression and outcomes. Expression of cardiomyopathy genes is under the regulatory control of promoters and enhancers, and human genetic variation in promoters and enhancers may contribute to this variability.
Targeting 5-HT2B Receptor Signaling Prevents Border Zone Expansion and Improves Microstructural Remodeling After Myocardial Infarction
J. Caleb Snider, Lance A. Riley, Noah T. Mallory, Matthew R. Bersi, Prachi Umbarkar, Rekha Gautam, Qinkun Zhang, Anita Mahadevan-Jansen, Antonis K. Hatzopoulos, Luc Maroteaux, Hind Lal, W. David Merryman
doi : 10.1161/CIRCULATIONAHA.120.051517
Circulation. 2021 | Volume 143, Issue 13: 1317–1330
Myocardial infarction (MI) induces an intense injury response that ultimately generates a collagen-dominated scar. Although required to prevent ventricular rupture, the fibrotic process is often sustained in a manner detrimental to optimal recovery. Cardiac myofibroblasts are the cells tasked with depositing and remodeling collagen and are a prime target to limit the fibrotic process after MI. Serotonin 2B receptor (5-HT2B) signaling has been shown to be harmful in a variety of cardiopulmonary pathologies and could play an important role in mediating scar formation after MI.
Flash Pulmonary Edema in a 70-Year-Old Man
Katherine Lutz, Cassie Mullen, Liat Litwin
doi : 10.1161/CIRCULATIONAHA.121.053333
Circulation. 2021 | Volume 143, Issue 13: 1331–1334
Prevalence of Atrial Fibrillation and Thromboembolic Risk in Wild-Type Transthyretin Amyloid Cardiomyopathy
Syed Bukhari, Amr F. Barakat, Yvonne S. Eisele, Ricardo Nieves, Sandeep Jain, Samir Saba, William P. Follansbee, Amy Brownell, Prem Soman
doi : 10.1161/CIRCULATIONAHA.120.052136
Circulation. 2021 | Volume 143, Issue 13: 1335–1337
Multiple Biomarker Approach to Risk Stratification in COVID-19
Nathaniel R. Smilowitz, Vuthy Nguy, Yindalon Aphinyanaphongs, Jonathan D. Newman, Yuhe Xia, Harmony R. Reynolds, Judith S. Hochman, Glenn I. Fishman, Jeffrey S. Berger
doi : 10.1161/CIRCULATIONAHA.120.053311
Circulation. 2021 | Volume 143, Issue 13: 1338–1340
Letter by Angiolillo et al Regarding Article, “Cangrelor, Tirofiban, and Chewed or Standard Prasugrel Regimens in Patients With ST-Segment–Elevation Myocardial Infarction: Primary Results of the FABOLUS FASTER Trial”
Dominick J. Angiolillo, Deepak L. Bhatt, Gregg W. Stone
doi : 10.1161/CIRCULATIONAHA.120.050205
Circulation. 2021 | Volume 143, Issue 13: e795–e796
Response by Gargiulo et al to Letter Regarding Article, “Cangrelor, Tirofiban, and Chewed or Standard Prasugrel Regimens in Patients With ST-Segment–Elevation Myocardial Infarction: Primary Results of the FABOLUS FASTER Trial”
Giuseppe Gargiulo, Michael Nagler, Marco Valgimigli
doi : 10.1161/CIRCULATIONAHA.120.051945
Circulation. 2021 | Volume 143, Issue 13: e797–e798
Correction to: Inhibition of Angiopoietin-Like Protein 3 With a Monoclonal Antibody Reduces Triglycerides in Hypertriglyceridemia
doi : 10.1161/CIR.0000000000000971
Circulation. 2021 | Volume 143, Issue 13: e799
