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Caution!! Reappearance of remimazolam effect after a flumazenil bolus: a larger bolus of flumazenil and a lower total remimazolam clearance are higher risks
Kenichi MasuiÂ
doi : 10.1007/s00540-022-03107-x
Volume 37, issue 1, February 2023
0.125% 8Â ml/h v.s. 0.25% 8Â ml/h of levobupivacaine in continuous paravertebral block for postoperative analgesia in video-assisted thoracoscopic surgery: a randomized, controlled, double-blind study
Sayuri Kawase, Toshinori Horiuchi & Toshihiro Nagahata
doi : 10.1007/s00540-022-03114-y
Research has shown that a higher dose of bupivacaine administered in continuous paravertebral block (CPVB) provides a greater analgesic effect after video-assisted thoracoscopic surgery (VATS).
Association between remimazolam and postoperative delirium in older adults undergoing elective cardiovascular surgery: a prospective cohort study
Yoshitaka Aoki, Tadayoshi Kurita, Mikio Nakajima, Ryo Imai, Yuji Suzuki, Hiroshi Makino, Hiroyuki Kinoshita, Matsuyuki Doi & Yoshiki Nakajima
doi : 10.1007/s00540-022-03119-7
Postoperative delirium is one of the most common complications after cardiovascular surgery in older adults. Benzodiazepines are a reported risk factor for delirium; however, there are no studies investigating remimazolam, a novel anesthetic agent. Therefore, we prospectively investigated the effect of remimazolam on postoperative delirium.
Predictive factors for favorable short-term response to interlaminar epidural block for cervical radiculopathy
Daeseok Oh, Soon Ho Cheong, Young Gyun Choi, Sung ho Moon & Myoung Jin Ko
doi : 10.1007/s00540-022-03122-y
We sought to identify clinical predictors of favorable short-term outcomes associated with cervical interlaminar epidural injection (CIEI). Previous studies investigating the predictive factors of CIEI efficacy have shown inconsistent results.
Comparison of thromboelastographic profiles in pediatric patients with congenital heart disease according to existence of cyanosis
Woon-Seok Kang, Seung-Wan Hong, Chung-Sik Oh, Tae-Gyoon Yoon, Byung-Soo Kim, Yubi Kwon & Seong-Hyop Kim
doi : 10.1007/s00540-022-03124-w
Congenital heart disease (CHD) is divided into two groups according to cyanosis status. Cyanotic CHD has a low level of systemic oxygenation and is accompanied by increased erythropoiesis. We hypothesized that pediatric patients with CHD would exhibit different thromboelastographic profiles according to their cyanosis status.
Obstetrical outcomes of labor with and without analgesia in Robson classification groups 1 and 2a: a single-center retrospective study
Taro Yagi, Yasuto Kinose, Michiko Bun, Megumi Horai, Chie Matsuda, Tatsuya Miyake, Kazuya Mimura, Chiyo Otaki, Masayuki Endo & Tadashi Kimura
doi : 10.1007/s00540-022-03125-9
This study aimed to elucidate the effects of neuraxial analgesia on labor in women classified based on the Robson classification system.
Characteristics of retained foreign bodies and near-miss events in the operating room: a ten-year experience at one institution
Kyosuke Takahashi, Takeshi Fukatsu, Sayaka Oki, Yusuke Iizuka, Yuji Otsuka, Masamitsu Sanui & Alan Kawarai Lefor
doi : 10.1007/s00540-022-03127-7
Retained foreign bodies (RFBs) are a major complication of surgical procedures. However, the efficacy of preventive measures is not well defined. This study investigates the characteristics of potential (near miss) and actual RFBs, and the contributions of routine practice for the prevention of RFB events.
Evaluation of fibrinogen concentration by clot firmness using a dielectric blood coagulation test system
Yulin Zeng, Yudai Yamamoto, Yoshihito Hayashi & Tokujiro Uchida
doi : 10.1007/s00540-022-03131-x
To determine if fibrinogen concentration can be evaluated by dielectric permittivity changes in dielectric blood coagulation testing (DBCM) during cardiovascular surgery with cardiopulmonary bypass (CPB).
Prevalence of pre-operative undiagnosed cognitive impairment and its association with handgrip strength, oral hygiene, and nutritional status in older elective surgical patients in Japan
Shohei Nakatani, Mitsuru Ida, Kayo Uyama, Yuki Kinugasa & Masahiko Kawaguchi
doi : 10.1007/s00540-022-03133-9
Preoperative cognitive impairment is a significant factor influencing post-operative delirium. We have been performing routine pre-operative comprehensive assessments, including evaluation of cognitive function, handgrip strength, oral hygiene, and nutritional status, in patients aged ≥ 65 years since April 2021.
Single-dose intravenous nefopam on postoperative catheter-related bladder discomfort in patients undergoing transurethral resection of prostate: a randomized, double-blind placebo-controlled trial
Fa-ngam Charoenpol, Nutchanok Khampitak, Charinee Aimnang, Kachit Pachirat, Wichien Sirithanaphol, Ukrit Rompsaithong, Pakorn Kiatsopit & Supanut Lumbiganon
doi : 10.1007/s00540-022-03130-y
Transurethral resection of prostate (TURP) with postoperative catheter traction can lead to significant catheter-related bladder discomfort (CRBD).
Prediction of postoperative respiratory depression and respiratory complications in patients on preoperative methadone
Ryu Komatsu, Michael G. Nash, Jiang Wu, Emily M. Dinges, Carlos M. Delgado & Laurent A. Bollag
doi : 10.1007/s00540-022-03134-8
We developed prediction models for postoperative respiratory depression and respiratory complications for 958 patients who were on methadone preoperatively.
Change in cerebral circulation during the induction of anesthesia with remimazolam
Takashi Soejima, Kentaro Ueda, Sakae Hasegawa, Hiromitsu Motoe, Kazufumi Okada, Yoichi M. Ito, Koji Hoshino & Yuji Morimoto
doi : 10.1007/s00540-022-03135-7
Remimazolam is a new ultra-short-acting benzodiazepine with unknown effects on cerebral circulation. We measured total cerebral hemoglobin concentrations, which reflect cerebral blood volume (CBV), and cerebral oxygen saturation, using time-domain near-infrared spectroscopy, which can measure the absolute values of cerebral hemoglobin concentrations.
Deep breathing alleviates propofol-induced pain: a prospective, randomized, single-blind study
Katsuaki Tanaka, Yuko Yoshizumi, Taku Hamada, Kiyonobu Nishikawa & Takashi Mori
doi : 10.1007/s00540-022-03136-6
Propofol is commonly used to induce general anesthesia; however, the pain caused during propofol injection is a disadvantage. This study aimed to assess whether deep breathing attenuates propofol injection pain.
The effect of tetrastarch on the endothelial glycocalyx layer in early hemorrhagic shock using fluorescence intravital microscopy: a mouse model
Tadao Ando, Kohji Uzawa, Takahiro Yoshikawa, Shingo Mitsuda, Yoshihiro Akimoto, Tomoko Yorozu & Akira Ushiyama
doi : 10.1007/s00540-022-03138-4
To investigate vascular endothelial dysfunction based on glycocalyx impairment in massive hemorrhage and to evaluate fluid therapy.
Effect of fibrinogen replacement therapy on bleeding outcomes and 1-year mortality in patients undergoing thoracic aortic surgery: a retrospective cohort study
Mutsuhito Kikura, Yoko Tobetto, Kaori Yamamoto, Masahiro Uraoka & Ritsuko Go
doi : 10.1007/s00540-022-03140-w
This study aimed to examine the effect of fibrinogen replacement therapy with cryoprecipitate or fibrinogen concentrate on bleeding outcomes and 1-year mortality in patients undergoing thoracic aortic surgery.
Analgesia nociception index and high frequency variability index: promising indicators of relative parasympathetic tone
Keisuke Yoshida, Shinju Obara & Satoki Inoue
doi : 10.1007/s00540-022-03126-8
At present, there is no objective and absolute measure of nociception, although various monitoring techniques have been developed.
Does pericapsular nerve group block have limited analgesia at the initial post-operative period? Systematic review and meta-analysis
Ahmed Farag, Nada Ibrahim Hendi & Rehab Adel Diab
doi : 10.1007/s00540-022-03129-5
Perioperative pain management related to hip surgical procedures is challenging. Pericapsular nerve group (PENG) block is a novel technique that is assumed to provide better analgesia in addition to its post-operative motor-sparing effect. In this review, we aim to assess the safety and efficacy of PENG block on pain management in patients undergoing hip surgeries.
The intraoperative motor-evoked potential when propofol was changed to remimazolam during general anesthesia: a case series
Shoto Yamada, Yukinori Akiyama, Shunsuke Tachibana, Kengo Hayamizu, Yusuke Kimura, Shuichi Hashimoto, Michiaki Yamakage & Nobuhiro Mikuni
doi : 10.1007/s00540-022-03112-0
Remimazolam is a short-acting benzodiazepine that was approved for clinical use in 2020. We report three patients who underwent surgery for cerebral and spinal cord tumors, in whom transcranial electrical stimulation-motor-evoked potential (TES-MEP) was successfully monitored under general anesthesia with remimazolam.
Correction to: The intraoperative motor-evoked potential when propofol was changed to remimazolam during general anesthesia: a case series
Shoto Yamada, Yukinori Akiyama, Shunsuke Tachibana, Kengo Hayamizu, Yusuke Kimura, Shuichi Hashimoto, Michiaki Yamakage & Nobuhiro Mikuni
Reply to “Re-sedation after a large dose of flumazenil�
Kenichi MasuiÂ
Remimazolam should be antagonized by an adequate flumazenil
Takehito Sato & Kimitoshi Nishiwaki
Titration of flumazenil during awake craniotomy
Hiroaki Murata, Akihiro Yokoyama & Tetsuya Hara
Tolerance to remimazolam at a high effect-site concentration
Kotaro Kida, Megumi Taguchi, Keita Uchiyama, Shoko Fujioka & Tsunehisa Tsubokawa
Letter to the editor on “association between remimazolam and post-operative delirium in older adults undergoing elective cardiovascular surgery: a prospective cohort study�
Tao Jia & Jinliang Teng
Response to a letter to the editor by Jia and Teng: remimazolam and postoperative delirium in older adults undergoing elective cardiovascular surgery
Yoshitaka Aoki & Yoshiki Nakajima
