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Say Yes or No to N2O?.
Ende, Holly B. 1; Rathmell, James P. 2; Wanderer, Jonathan P. 3
Instructions for Obtaining ANESTHESIOLOGY Continuing Medical Education (CME) Credit.
Nitrous Oxide and Postoperative Pulmonary Complications: Conflicting Evidence.
Gama de Abreu, Marcelo M.D., M.Sc., Ph.D., D.E.S.A.I.C. 1; Sessler, Daniel I. M.D. 2
Modulating the Cardiac Autonomic Nervous System: Stay Close to My Heart or Keep Your Distance?.
Bartels, Karsten M.D., Ph.D., M.B.A. 1; Fox, Amanda A. M.D., M.P.H. 2
Respiratory Rate as a Factor in Lung Injury-Not Just What You Set, but How You Set.
Uchida, Kanji M.D., Ph.D. 1
Postoperative Pulmonary Complications in the ENIGMA II Trial: A Post Hoc Analysis.
Peyton, Philip J. M.D., Ph.D., M.B.B.S., F.A.N.Z.C.A. 1; Liskaser, Grace M.D. 2; Ho, Alexander M.B.B.S. 3; Marsh, Harry M.D., F.A.N.Z.C.A. 4; Etherington, Christopher M.B.B.S. 5; Torlot, Frederick M.B.B.S., B.Sc., M.R.C.P. 6; Desai, Manisha M.B.B.S., F.A.N.Z.C.A. 7; Perrett, George M.B.B.S., B.Sc. (Hon.), F.R.C.A. 8; Chee, Brian M.B.B.S., F.A.N.Z.C.A. 9; Leslie, Kate M.B.B.S., M.D., M.Epid., M.Hlth.Serv.Mt.; Hon. D. Med. Sci., F.A.N.Z.C.A. 10; Myles, Paul S. M.D., D.Sc., M.P.H., F.A.N.Z.C.A. 11
doi : 10.1097/ALN.0000000000004497
Nitrous oxide promotes absorption atelectasis in poorly ventilated lung segments at high inspired concentrations. The Evaluation of Nitrous oxide In the Gas Mixture for Anesthesia (ENIGMA) trial found a higher incidence of postoperative pulmonary complications and wound sepsis with nitrous oxide anesthesia in major surgery compared to a fraction of inspired oxygen of 0.8 without nitrous oxide.
Immediate Hypersensitivity to Chlorhexidine: Experience from an Allergy Center in China.
Xiao, Hao M.S. 1; Zhang, Hongting B.S. 2; Jia, Qiaoru B.S. 3; Xu, Feng M.S. 4; Meng, Juan M.D., Ph.D. 5
doi : 10.1097/ALN.0000000000004495
Chlorhexidine generally has a good safety profile. However, allergic reactions are reported with increasing frequency. In China, it is rarely reported, and its characteristics are unknown.
GABAergic Signaling during Spinal Cord Stimulation Reduces Cardiac Arrhythmias in a Porcine Model.
Howard-Quijano, Kimberly M.D., M.S. 1; Kuwabara, Yuki M.D. 2; Yamaguchi, Tomoki M.D. 3; Roman, Kenny Ph.D. 4; Salavatian, Siamak Ph.D. 5; Taylor, Bradley Ph.D. 6; Mahajan, Aman M.D., Ph.D., M.B.A. 7
doi : 10.1097/ALN.0000000000004516
Neuraxial modulation, including spinal cord stimulation, reduces cardiac sympathoexcitation and ventricular arrhythmogenesis. There is an incomplete understanding of the molecular mechanisms through which spinal cord stimulation modulates cardiospinal neural pathways.
Dr. Silas Weir Mitchell: The Nightmare of War and the Death of Pain.
Intergenerational Perioperative Neurocognitive Disorder in Young Adult Male Rats with Traumatic Brain Injury.
Ju, Ling-Sha M.S. 1; Zhu, Jiepei M.D., Ph.D. 2; Brant, Jason O. Ph.D. 3; Morey, Timothy E. M.D. 4; Gravenstein, Nikolaus M.D. 5; Seubert, Christoph N. M.D., Ph.D. 6; Vasilopoulos, Terrie Ph.D. 7; Setlow, Barry Ph.D. 8; Martynyuk, Anatoly E. Ph.D. 9
doi : 10.1097/ALN.0000000000004496
The authors tested the hypothesis that the effects of traumatic brain injury, surgery, and sevoflurane interact to induce neurobehavioral abnormalities in adult male rats and in their offspring (an animal model of intergenerational perioperative neurocognitive disorder).
Mouse Model of Spinal Cord Hypoperfusion with Immediate Paralysis Caused by Endovascular Repair of Thoracic Aortic Aneurysm.
Kelani, Hesham M.D. 1; Corps, Kara D.V.M. 2; Mikula, Sarah B.A. 3; Fisher, Lesley C. B.S. 4; Shalaan, Mahmoud T. B.Pharm. 5; Sturgill, Sarah M.S. 6; Ziolo, Mark T. Ph.D. 7; Abdel-Rasoul, Mahmoud M.S., M.P.H. 8; Basso, D. Michele Ed.D., P.T. 9; Awad, Hamdy M.D. 10
doi : 10.1097/ALN.0000000000004515
A clinically relevant mouse model of thoracic endovascular aortic repair-induced ischemic spinal cord injury has been lacking since the procedure was first employed in 1991.
Lung Injury Is Induced by Abrupt Increase in Respiratory Rate but Prevented by Recruitment Maneuver in Mild Acute Respiratory Distress Syndrome in Rats.
Xavier, Paulo Henrique M.D. 1; Fonseca, Ana Carolina Fernandes M.D. 2; Goncalves, Leonardo Alves M.D. 3; de Sousa, Giselle Cavalho M.D. 4; Silva, Mariana Coelho da M.D. 5; Sacramento, Raquel Ferreira de Magalhaes Ph.D. 6; Samary, Cynthia dos Santos Ph.D. 7; Medeiros, Mayck B.Sc. 8; Cruz, Fernanda Ferreira M.D., Ph.D. 9; Capelozzi, Vera Luiza M.D., Ph.D. 10; Felix, Nathane Satanna M.D., Ph.D. 11; Pelosi, Paolo M.D. 12; Marini, John J. M.D. 13; Rocco, Patricia Rieken Macedo M.D., Ph.D. 14; Silva, Pedro Leme Ph.D. 15
doi : 10.1097/ALN.0000000000004479
Gradually changing respiratory rate (RR) during time to reduce ventilation-induced lung injury has not been investigated. The authors hypothesized that gradual, compared with abrupt, increments in RR would mitigate ventilation-induced lung injury and that recruitment maneuver before abruptly increasing RR may prevent injurious biologic impact.
Luck, an Inquisitive Mind, and Opportunities: Lessons Learned: A Blinded Study of Pulse Oximetry before It Became a Standard of Care.
Cote, Charles J. M.D. 1
doi : 10.1097/ALN.0000000000004486
AB A Single-blind Study of Pulse Oximetry in Children. By CJ Cote, EA Goldstein, MA Cote, DC Hoaglin, and JF Ryan. Anesthesiology 1988; 68:184-8. Reprinted with permission. Oxygen saturation determined by pulse oximetry was monitored in 152 pediatric surgical patients divided into two groups.
Segmental Tracheomalacia in a Patient with a Persistent Air Leak.
Powers, Sean W. D.O. 1; Metry, Jonathan M.D. 2; Kutlu, Kathryn S. M.D. 3
Updates in Prevention of Surgical Site Infection: Comment.
Mundangepfupfu, Tichaendepi M.D., M.Res. 1; Nadler, Jacob W. M.D., Ph.D.
Updates in Prevention of Surgical Site Infection: Reply.
Long, Dustin R. M.D. 1; Alverdy, John C. M.D., F.A.C.S.; Vavilala, Monica S. M.D.
Selection Bias in the Hypotension Prediction Index: Comment.
Giustiniano, Enrico M.D. 1; Nisi, Fulvio M.D.
Selection Bias in the Hypotension Prediction Index: Reply.
Enevoldsen, Johannes M.D. 1; Hovgaard, Henrik L. M.D.; Vistisen, Simon T. M.Sc., Ph.D.
Authors and Editors Must Consider Appropriate Use of Acronyms and Initialisms, or Text Will Be DOA (Dead on Arrival).
Schwartz, Alan Jay M.D., M.S.Ed. 1
Hyperoxia and Antioxidants for Myocardial Injury in Noncardiac Surgery: A 2 x 2 Factorial, Blinded, Randomized Clinical Trial: Erratum.
Postoperative Delirium after Dexmedetomidine versus Propofol Sedation in Healthy Older Adults Undergoing Orthopedic Lower Limb Surgery with Spinal Anesthesia: A Randomized Controlled Trial: Erratum.
