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Biomarkers for Delirium: The Search Continues.
Nathan, Naveen MD
doi : 10.1213/ANE.0000000000006389
Volume 136(3) pgs. 421-621,e15-e20 March 2023
Proteomics for the Discovery of Clinical Delirium Biomarkers: A Systematic Review of Major Studies.
Wiredu, Kwame MBChB *,+; Aduse-Poku, Edmund BA ++; Shaefi, Shahzad MD, MPH [S]; Gerber, Scott A. PhD *,+,[//]
doi : 10.1213/ANE.0000000000006246
AB Delirium represents a significant health care burden, diagnosed in more than 2 million elderly Americans each year. In the surgical population, delirium remains the most common complication among elderly patients, and is associated with longer hospital stays, higher costs of care, increased mortality, and functional impairment.
The Future of Pediatric Anesthesiology Training.
Nathan, Naveen MD
Creating the Pediatric Anesthesiology Consultant: You Can't Have Your Cake and Eat It Too (Unless You Change the Recipe).
Cladis, Franklyn P. MD, MBA *; Waisel, David MD +
A Consensus-Driven Approach to Redesigning Graduate Medical Education: The Pediatric Anesthesiology Delphi Study.
Ambardekar, Aditee P. MD, MSEd *; Eriksen, Whitney PhD, RN +; Ferschl, Marla B. MD ++; McNaull, Peggy P. MD [S]; Cohen, Ira T. MD, MEd [//]; Greeley, William J. MD, MBA [P]; Lockman, Justin L. MD, MSEd #,**
doi : 10.1213/ANE.0000000000006128
Pediatric anesthesiology fellowship education has necessarily evolved since Accreditation Council for Graduate Medical Education (ACGME) accreditation in 1997.
A Consensus-Driven Revision of the Accreditation Council for Graduate Medical Education Case Log System: Pediatric Anesthesiology Fellowship Education.
Ambardekar, Aditee P. MD, MSEd *,+; Furukawa, Louise MD *,+; Eriksen, Whitney PhD, RN ++; McNaull, Peggy P. MD [S]; Greeley, William J. MD, MBA [//]; Lockman, Justin L. MD, MSEd [P],#
doi : 10.1213/ANE.0000000000006129
Clinical experiences, quantified by case logs, are an integral part of pediatric anesthesiology fellowship programs. Accreditation of pediatric anesthesiology fellowships by the Accreditation Council of Graduate Medical Education (ACGME) and establishment of case log reporting occurred in 1997 and 2009, respectively.
Anatomy for the Adductor Canal Block: Does Location Really Matter?.
Orebaugh, Steven L. MD *; Barrington, Michael MBBS, PhD +
Pro and Con: How Important Is the Exact Location of Adductor Canal and Femoral Triangle Blocks?.
Woodworth, Glenn E. MD *; Arner, Andrew MD +; Nelsen, Sylvia PhD ++; Nada, Eman MD, PhD [S]; Elkassabany, Nabil M. MD, MSCE [//]
doi : 10.1213/ANE.0000000000006234
AB In this Pro-Con commentary article, we debate the importance of anterior thigh block locations for analgesia following total knee arthroplasty. The debate is based on the current literature, our understanding of the relevant anatomy, and a clinical perspective.
FEIBA Use in Neonatal Cardiac Surgery: A Risky Business That Needs Further Investigation.
Faraoni, David MD, PhD *; Sniecinski, Roman M. MD, MSc +
Activated 4-Factor Prothrombin Complex Concentrate as a Hemostatic Adjunct for Neonatal Cardiac Surgery: A Propensity Score-Matched Cohort Study.
Navaratnam, Manchula MBChB, FRCA *; Mendoza, Julianne M. MD *; Zhang, Shiqi MS +; Boothroyd, Derek PhD +; Maeda, Katsuhide MD, PhD ++; Kamra, Komal MBBS, MMI *; Williams, Glyn D. MBChB, FFA *
doi : 10.1213/ANE.0000000000006294
Prothrombin complex concentrates are an emerging "off-label" therapy to augment hemostasis after cardiopulmonary bypass (CPB), but data supporting their use for neonatal cardiac surgery are limited.
High-Flow Nasal Cannula for Apneic Oxygenation in Obese Patients for Elective Surgery: A Systematic Review and Meta-Analysis.
Bright, Matthew R. MD *,+; Harley, William A. MD +,++; Velli, Gina MInfoMgt [S]; Zahir, Syeda Farah PhD [//]; Eley, Victoria PhD *,+
doi : 10.1213/ANE.0000000000006304
Obese patients desaturate rapidly during the apneic period after induction of anesthesia for elective surgery. Administration of oxygen using high-flow nasal cannulae (HFNCs) may prevent desaturation in nonobese patients compared to facemask (FM) preoxygenation.
Appropriate Duration of Perioperative Intravenous Administration of Lidocaine to Provide Satisfactory Analgesia for Adult Patients Undergoing Colorectal Surgery: A Meta-Analysis of Randomized Controlled Trials.
Yang, Wei MD *,+; Yan, Siyu MD *,+; Yu, Feng MD *,+; Jiang, Chunling MD, PhD *,+
doi : 10.1213/ANE.0000000000006347
Perioperative lidocaine infusion has been reported to alleviate pain intensity after colorectal surgery. However, there is no consensus on whether prolonged lidocaine infusion is more effective than short lidocaine infusion. This meta-analysis aimed to determine an appropriate duration of lidocaine infusion in patients undergoing colorectal surgery.
Derivation and Validation of Clinical Phenotypes of the Cardiopulmonary Bypass-Induced Inflammatory Response.
Milam, Adam J. MD, PhD *; Liang, Chen MS +,++; Mi, Junhui MS +,++; Mascha, Edward J. PhD +,++; Halvorson, Sven MS +,++; Yan, Manshu MD *; Soltesz, Edward MD, MPH [S]; Duncan, Andra E. MD, MS *,++
doi : 10.1213/ANE.0000000000006247
Precision medicine aims to change treatment from a "one-size-fits-all" approach to customized therapies based on the individual patient. Applying a precision medicine approach to a heterogeneous condition, such as the cardiopulmonary bypass (CPB)-induced inflammatory response, first requires identification of homogeneous subgroups that correlate with biological markers and postoperative outcomes.
Incidence of Postreperfusion Hyperfibrinolysis in Liver Transplantation by Donor Type and Observed Treatment Strategies.
Krom, Russell J. MD, PhD; Welsby, Ian J. MBBS; Fuller, Matthew MS; Barbas, Andrew S. MD; Gao, Qimeng MD, MHS; Anwar, Imran J. MD; Dunkman, W. Jonathan MD
Patient and Operative Factors Predict Risk of Discretionary Prolonged Postoperative Mechanical Ventilation in a Broad Surgical Cohort.
Clark, Michael G. BS *; Mueller, Dorothee A. MD +; Dudaryk, Roman MD ++; Li, Gen MStat, MChem +; Freundlich, Robert E. MD, MS, MSCI +[S]
doi : 10.1213/ANE.0000000000006205
Patients undergoing surgery with general anesthesia and endotracheal intubation are ideally extubated upon case completion, as prolonged postoperative mechanical ventilation (PPMV) has been associated with poor outcomes.
Randomized Assessment of the Optimal Time Interval Between Programmed Intermittent Epidural Boluses When Combined With the Dural Puncture Epidural Technique for Labor Analgesia.
Yao, Han-Qing MD *; Huang, Jia-Yue MD *; Deng, Jia-Li MD *; Liu, Lin MD *; Ai, Ling MD +; Kee, Warwick D. Ngan MD, FANZCA, FHKCA ++; Xiao, Fei MD *
doi : 10.1213/ANE.0000000000006201
The dural puncture epidural (DPE) and programmed intermittent epidural bolus (PIEB) techniques are recent advances in neuraxial labor analgesia. Previous studies have investigated the PIEB optimal interval for effective analgesia when a standard epidural technique is used to initiate labor analgesia.
Manually Controlled, Continuous Infusion of Phenylephrine or Norepinephrine for Maintenance of Blood Pressure and Cardiac Output During Spinal Anesthesia for Cesarean Delivery: A Double-Blinded Randomized Study.
Belin, Olivier MD *; Casteres, Charlotte MD *; Alouini, Souhail MD +; Le Pape, Marc MD *; Dupont, Abderrahmane MD *; Boulain, Thierry MD ++
doi : 10.1213/ANE.0000000000006244
To counteract the vasoplegia induced by spinal anesthesia (SA) and maintain blood pressure (BP) during cesarean delivery, phenylephrine is currently recommended, but norepinephrine might offer superior preservation of cardiac output.
Age-Stratified Propofol Dosage for Pediatric Procedural Sedation and Analgesia.
van Dijk, Huib MD; Hendriks, Mark P. MD; van Eck-Smaling, Marga M. BSc; van Wolfswinkel, Leo MD, PhD; van Loon, Kim MD, PhD
doi : 10.1213/ANE.0000000000006196
Procedural sedation and analgesia (PSA) for diagnostic and minimally invasive therapeutic procedures has become common practice in children of all ages. Based on our clinical experience, we suspected an inverse relation between age and dosage.
Sugammadex Versus Neostigmine for Recovery of Respiratory Muscle Strength Measured by Ultrasonography in the Postextubation Period: A Randomized Controlled Trial.
Huang, Chanyan MD *; Wang, Xuan MD *; Gao, Shaowei MD *; Luo, Wei MD *; Zhao, Xu MD *; Zhou, Qian MD +; Huang, Wenqi PhD *; Xiao, Ying PhD *
doi : 10.1213/ANE.0000000000006219
Although sugammadex is well known for its use in reducing the incidence of residual neuromuscular blockade, this has not always been translated to improved clinical measures of postoperative respiratory muscle strength.
Oral Dantrolene for Myopathic Symptoms in Malignant Hyperthermia-Susceptible Patients: A 25-Year Retrospective Cohort Study of Adverse Effects and Tolerability.
Ibarra Moreno, Carlos A. MD, PhD *; Kraeva, Natalia PhD *; Zvaritch, Elena PhD *; Jungbluth, Heinz MD, PhD +,++; Voermans, Nicol C. MD, PhD [S]; Riazi, Sheila MSc, MD *
doi : 10.1213/ANE.0000000000006207
Patients susceptible to malignant hyperthermia (MH) may experience disabling manifestations of an unspecified myopathy outside the context of anesthesia, including myalgia, fatigue, or episodic rhabdomyolysis.
Perioperative Tracking of Intravenous Iron in Patients Undergoing On-Pump Cardiac Surgery: A Prospective, Single-Center Pilot Trial.
Olivier, Roman M. R. MD *; Macke, Marcel MSc +; Muller, Jennifer C. PhD +; Schrader, Lisa PhD *; Eveslage, Maria Dipl-Stat ++; Rauer, Marcel MD *; Wempe, Carola PhD *; Martens, Sven MD [S]; Zarbock, Alexander MD *; Wagner, Nana-Maria MD, MHBA *; Karst, Uwe PhD +; Dogan, Deniz Y. MD *,||; Steinbicker, Andrea U. MD, MPH *,||; Oguama, David; Brunen, Andreas
doi : 10.1213/ANE.0000000000006372
Preoperative intravenous iron administration is a frequently used patient blood management procedure. If the timeframe of intravenous iron administration before surgery is short, (1) the concentration of the intravenous iron compound might still be high in patients' plasma when undergoing surgery and (2) this iron in patients' plasma is at risk to be lost due to blood loss.
Investigating the Association Between a Risk-Directed Prophylaxis Protocol and Postoperative Nausea and Vomiting: Validation in a Low-Income Setting.
Tuyishime, Jean de Dieu H. MD, MMed *; Niyitegeka, Joseph MD, MMed *; Olufolabi, Adeyemi J. MBBS, FRCA +; Powers, Samuel MA ++; Naik, Bhiken I. MBBCh, MSCR [S]; Tsang, Siny PhD [S]; Durieux, Marcel E. MD, PhD [S]; Twagirumugabe, Theogene MD, MMed, FCCM, PhD *
doi : 10.1213/ANE.0000000000006251
The efficacy of postoperative nausea and vomiting (PONV) prevention protocols in low-income countries is not well known. Different surgical procedures, available medications, and co-occurring diseases imply that existing protocols may need validation in these settings.
Anatomical and Radiological Assessments of Injectate Spread Stratified by the Volume of the Pericapsular Nerve Group Block.
Kim, Ji Yeong MD *; Kim, Jiyoung MD +; Kim, Do-Hyeong MD, PhD *; Han, Dong Woo MD, PhD *; Kim, Sang Hyun MD ++; Kim, Donghyun MD +; Chung, Siwook MD +; Yu, Sanghyuck MD +; Lee, U-Young MD, PhD ++; Park, Hue Jung MD, PhD +
doi : 10.1213/ANE.0000000000006364
The pericapsular nerve group (PENG) block was recently suggested as a regional technique for managing acute pain after hip surgery. However, few anatomical studies have confirmed the spread of injectate during the PENG block.
Benefit of Flow-Controlled Over Pressure-Regulated Volume Control Mode During One-Lung Ventilation: A Randomized Experimental Crossover Study.
Schranc, Almos MD *; Diaper, John MSc *; Sudy, Roberta MD, PhD *; Fodor, Gergely H. MD, PhD +; Habre, Walid MD, PhD *,++; Albu, Gergely MD, PhD *,[S]
doi : 10.1213/ANE.0000000000006322
Application of a ventilation modality that ensures adequate gas exchange during one-lung ventilation (OLV) without inducing lung injury is of paramount importance.
Anesthesiologists and Voter Advocacy: A Novel Avenue for Civic Outreach.
Fisher, Andrew D. MD; Fisher, Gabrielle MD
Advice to a Medical Student Contemplating Anesthesiology.
Shafer, Audrey MD
Toward a Better Understanding and Narrower Gender and Racial Gaps in the Diagnosis and Treatment of Valvular Heart Disease.
Windrix, Casey MD; Vandyck, Kofi MD; Stewart, Kenneth PhD; Tanaka, Kenichi MD, MSc
In Response.
White, Robert S. MD, MS; Bradley, Stephanie MD, MPH; Tangel, Virginia E. MA, MSc; Rong, Lisa Q. MD, MSCE
What Is the Best Monitoring Strategy for Platelet Function: Aggregability Count or Elasticity?.
Terada, Rui MD, PhD; Windrix, Casey MD; Tanaka, Kenichi A. MD, MSc; Stewart, Kenneth E. PhD
In Response.
Baryshnikova, Ekaterina PhD; Di Dedda, Umberto MD; Ranucci, Marco MD, FESC
Perioperative Quality Initiative and Enhanced Recovery After Surgery-Cardiac Society Consensus Statement on the Management of Preoperative Anemia and Iron Deficiency in Adult Cardiac Surgery Patients: Erratum.
