doi : 10.1016/S0007-0912(23)00086-7
Volume 130, Issue 4, April 2023, Page ii
Stuart M. White 1,* , Tiffany Tedore 2 and Clifford L. Shelton
doi : 10.1016/j.bja.2023.01.013
Volume 130, Issue 4, April 2023, Pages 385-389
Bernd Saugel 1,2,* , Kristen K. Thomsen 1 and Kamal Maheshwari
doi : 10.1016/j.bja.2022.12.022
Volume 130, Issue 4, April 2023, Pages 390-393
Laszlo Vutskits
doi : 10.1016/j.bja.2023.01.003
Volume 130, Issue 4, April 2023, Pages 393-395
Thomas Payne 1,2 , Ben Moran 3,4,5,6 , John Loadsman 1,2 , Ian Marschner 7 , Tim McCulloch 1,2 and Robert D. Sanders
doi : 10.1016/j.bja.2023.01.011
Volume 130, Issue 4, April 2023, Pages 395-401
Robert G. Loeb
doi : 10.1016/j.bja.2023.01.014
Volume 130, Issue 4, April 2023, Pages 401-403
Alexander I. R. Jackson 1,2, *, Oliver Boney 3,4 , Rupert M. Pearse 5 , Andrea Kurz 6 , D. James Cooper 7,8 , Wilton A. van Klei 9,10,11 , Luca Cabrini 12 , Timothy E. Miller 13 , S. Ramani Moonesinghe 14,15,16 , Paul S. Myles17,18 , Michael P. W. Grocott
doi : 10.1016/j.bja.2022.12.012
Volume 130, Issue 4, April 2023, Pages 404-411
Mortality, morbidity, and organ failure are important and common serious harms after surgery. However, there are many candidate measures to describe these outcome domains. Definitions of these measures are highly variable, and validity is often unclear. As part of the International Standardised Endpoints in Perioperative Medicine (StEP) initiative, this study aimed to derive a set of standardised and valid measures of mortality, morbidity, and organ failure for use in perioperative clinical trials.
Zachary Chuang 1 , Janet Martin 1,2,3 , Jordan Shapiro 1 , Derek Nguyen 1 , Penelope Neocleous 1 and Philip M. Jones
doi : 10.1016/j.bja.2022.11.001
Volume 130, Issue 4, April 2023, Pages 412-420
Reproducibility of research is poor; this may be because many articles report statistically significant findings that are false positives. Two potential solutions are to lower the P-value for statistical significance testing from 0.05 to 0.005 and to report the minimum false-positive risk (minFPR). This study determined these metrics for randomised controlled trials (RCTs) in general anaesthesiology journals.
Rui Terada 1 , Kenneth Stewart 1,2 , Sandra Hansen 1 , Shashank S. Shettar1 , Amir Butt 1 , Santaram Vallurupalli 3 , Michael Martin 4 and Kenichi Tanaka
doi : 10.1016/j.bja.2022.11.020
Volume 130, Issue 4, April 2023, Pages 421-429
Allogeneic blood transfusion used to be common in spine surgery. Patient blood management has been widely adopted, and it is important to reassess transfusion predictors in contemporary practice.
Jayyoung Bae 1,y, Jun Sung Lee 2,y, Jooyoung Oh 3 , Dong Woo Han 1 , Heejae Jung 1 , Seok-Mo Kim 2,y and Young Song
doi : 10.1016/j.bja.2022.12.003
Volume 130, Issue 4, April 2023, Pages 430-438
Left-sided frontal alpha asymmetry on electroencephalograms, which indicates decreased relative left-hemispheric activity, has been associated with depression, anxiety, and stress responsivity. We aimed to evaluate the association between perioperative measures of frontal alpha asymmetry and quality of recovery (QoR) after surgery.
Seohee Lee 1 , Jin Young Sohn 1 , In Eob Hwang 1 , Ho-Jin Lee 1 , Susie Yoon 1 , Jae-Hyon Bahk 1 and Bo Rim Kim
doi : 10.1016/j.bja.2022.12.009
Volume 130, Issue 4, April 2023, Pages 439-445
An orientation strategy providing repeated verbal reminders of time, place, and person has been widely used for the non-pharmacological management of delirium. We hypothesised that using this strategy could reduce emergence agitation and improve recovery profiles.
Zheng Xu1,2,3,y, Su-Wan Hu 1,2,3,y, Yu Zhou 1,2,3,y, Qingchen Guo 1,2,3 , Di Wang 1,2,3 , Yi-Hong Gao 1,2,3 , Wei-Nan Zhao 1,2,3 , Hui-Mei Tang 1,2,3 , Jun-Xia Yang 1,2,3 , Xiaolu Yu1,2,3 , Hai-Lei Ding 1,2,3, * and Jun-Li Cao
doi : 10.1016/j.bja.2022.12.020
Volume 130, Issue 4, April 2023, Pages 446-458
Corticotropin-releasing factor (CRF) neurones in the paraventricular nucleus (PVN) of the hypothalamus (PVNCRF neurones) can promote wakefulness and are activated under anaesthesia. However, whether these neurones contribute to anaesthetic effects is unknown.
Heather E. van Brug 1,2, *, Rob G. H. H. Nelissen 1,3 , Frits R. Rosendaal 2 , Liza N. van Steenbergen 3 , Eveline L. A. van Dorp 4 , Marcel L. Bouvy 5 , Albert Dahan 4 and Maaike G. J. Gademan
doi : 10.1016/j.bja.2022.12.024
Volume 130, Issue 4, April 2023, Pages 459-467
We determined the first prescribed opioid and the prescribers of opioids after knee and hip arthroplasty (KA/HA) between 2013 and 2018 in the Netherlands. We also evaluated whether the first prescribed opioid dose was associated with the total dispensed dose and long-term opioid use in the first postoperative year.
Amour B. U. Patel 1 , Phillip P. W. M. Bibawy 2 , Juri Ibrahim M. Althonayan 2 , Zehra Majeed 1 , Weng L. Gan 2 , Tom E. F. Abbott 1 and Gareth L. Ackland
doi : 10.1016/j.bja.2022.12.025
Volume 130, Issue 4, April 2023, Pages 468-476
Activation of central autonomic pathways, including those regulating the arterial baroreflex, might reduce acute pain. We tested the hypothesis that transcutaneous auricular nerve stimulation (TAN) reduces pain after orthopaedic trauma surgery through autonomic modulation.
Kim C. Koschmieder 1,y, Sandra Funcke 1,y, Mahshid Shadloo 1 , Hans O. Pinnschmidt2 , Gillis Greiwe 1 , Marlene Fischer 1 and Rainer Nitzschke 1,
doi : 10.1016/j.bja.2022.11.024
Volume 130, Issue 4, April 2023, Pages 477-484
Nociception monitoring devices are designed to estimate nociception during general anaesthesia. We evaluated the predictive accuracy of heart rate and three nociception indices to predict postoperative pain before emergence from general anaesthesia.
Cornelis Jan van Dam 1 , Rutger van der Schrier 1 , Monique van Velzen 1 , Maarten van Lemmen 1 , Pieter Simons 1 , Kiki W. K. Kuijpers 1 , Simone Jansen 1 , Mikael A. Kowal 2 , Erik Olofsen 1 , Cornelis Kramers 3 , Albert Dahan 1,4, * and Marieke Niesters
doi : 10.1016/j.bja.2022.12.018
Volume 130, Issue 4, April 2023, Pages 485-493
In humans, the effect of cannabis on ventilatory control is poorly studied, and consequently, the effect of Δ9-tetrahydrocannabinol (THC) remains unknown, particularly when THC is combined with an opioid. We studied the effect of THC on breathing without and with oxycodone pretreatment. We hypothesised that THC causes respiratory depression, which is amplified when THC and oxycodone are combined.
James Penketh* , Fiona E. Kelly and Timothy M. Cook
doi : 10.1016/j.bja.2022.12.023
Volume 130, Issue 4, April 2023, Pages e425-e426
Neil Bhattacharyya 1 , Andres Zorrilla-Vaca2,* , Marielle Schmitt3 and Gustavo Lozada
doi : 10.1016/j.bja.2022.12.016
Volume 130, Issue 4, April 2023, Pages e427-e428
Reena Ellis1,* , Marianna Laviola2 , Daniel Stolady3 , Rebecca L. Valentine 2 , Arani Pillai 1 and Jonathan G. Hardman
doi : 10.1016/j.bja.2023.01.007
Volume 130, Issue 4, April 2023, Pages e429-e430
Sebastiano M. Colombo1 , Vittorio Scaravilli 1,2,* , Luigi Castagna 1 , Alberto Zanella 1,3 , Matteo Brioni 1 , Chiara Abbruzzese1 and Giacomo Grasselli
doi : 10.1016/j.bja.2023.01.004
Volume 130, Issue 4, April 2023, Pages e430-e432
Roberto Santa Cruz1,2,3,* , Matı �as Rodriguez3 , Gustavo Scarpa3 and Romina Fernandez
doi : 10.1016/j.bja.2023.01.015
Volume 130, Issue 4, April 2023, Pages e433-e434
Santosh Patel
doi : 10.1016/j.bja.2022.12.015
Volume 130, Issue 4, April 2023, Pages e435-e440
Eline S. de Klerk1,2 , Midas N. de Grunt1 , Markus W. Hollmann 1,2 , Benedikt Preckel1,2 , Jeroen Hermanides1,2 and Mireille F. M. van Stijn
doi : 10.1016/j.bja.2022.12.017
Volume 130, Issue 4, April 2023, Pages e440-e442
Penghui Wei1,2,y, Haotian Ye2,y, Jianjun Li 1 and Jian-jun Yang
doi : 10.1016/j.bja.2022.12.019
Volume 130, Issue 4, April 2023, Pages e442-e443
Ilya Kantsedikas1,* and Peter Brooks
doi : 10.1016/j.bja.2023.01.006
Volume 130, Issue 4, April 2023, Pages e443-e444
Swetha Pakala 1,2 , Mark Brouillette1,2 , DeSean Thom1 , Mary J. Hargett 1 , Niyam Reddy1 , Ejiro Gbaje1 and Niharika Thakkar
doi : 10.1016/j.bja.2023.01.010
Volume 130, Issue 4, April 2023, Pages e445-e447
Marissa Weber and Mandisa-Maia Jones
doi : 10.1016/j.bja.2023.01.017
Volume 130, Issue 4, April 2023, Page 494
William Fitch 1 , Graham Smith 2 , Jennifer M. Hunter 3, *, Charles S. Reilly 4 , Ravi P. Mahajan 5 and Hugh C. Hemmings Jr.
doi : 10.1016/j.bja.2023.01.009
Volume 130, Issue 4, April 2023, Page 495
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