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Disorders of Gut-Brain Axis: Blurring the Lines Between Silos in Healthcare Delivery.
Darbari, Anil MD, MBA *
doi : 10.1097/MPG.0000000000003686
Volume 76(3) pgs. 269-399,e46-e70 March 2023
Clinical Hypnosis for Pediatric Gastrointestinal Disorders: A Practical Guide for Clinicians.
Chogle, Ashish MD, MPH *; Lee, Amanda MD +; Santucci, Neha R. MD ++; Yeh, Ann Ming MD [S]; Prozialeck, Joshua D. MD ||; Borlack, Rachel E. MD [P]; van Tilburg, Miranda A.L. PhD #,**,++
doi : 10.1097/MPG.0000000000003651
AB Functional abdominal pain disorders (FAPDs) are common in the pediatric population and are associated with a significant reduction in quality of life. Bidirectional communication of the brain-gut axis plays an important role in pain generation and perception in FAPDs.
Nutri-Score: Its Benefits and Limitations in Children's Feeding.
Chouraqui, Jean-Pierre MD, MSc *,+; Dupont, Christophe MD, PhD ++; Briend, Andre MD, PhD [S],||; Darmaun, Dominique MD, PhD [P]; Peretti, Noel MD, PhD #; Bocquet, Alain MD **; Chalumeau, Martin MD, PhD ++,++++; De Luca, Arnaud MD, PhD [S][S]; Feillet, Francois MD, PhD ||||; Frelut, Marie-Laure MD [P][P]; Guimber, Dominique MD ##; Lapillonne, Alexandre MD, PhD ***; Linglart, Agnes MD, PhD +++; Roze, Jean-Christophe MD, PhD ++++++; Simeoni, Umberto MD, PhD [S][S][S]; Turck, Dominique MD ||||||; Committee on Nutrition of the French Society of Pediatrics (CN-SFP)
doi : 10.1097/MPG.0000000000003657
AB Reducing the burden of noncommunicable diseases (NCDs) is one of the top priorities of public health policies worldwide. One of the recognized means of achieving this objective is to improve the diet quality. The Nutri-Score (N-S) is a [five-color-A, B, C, D, E letters] front-of-pack labeling logo intended to help consumers quickly identify the healthier prepackaged foods within a food category.
Intensive Outpatient Treatment of Pediatric Rumination Syndrome in the Era of Telemedicine.
Hawa, Kathryn DO *; Lu, Peter L. MD, MS *; Holzmacher, Meghan BS +; Wall, Jody PA-C *; Bali, Neetu MD, MPH *; Vaz, Karla MD, MEd *; Yacob, Desale MD *; Di Lorenzo, Carlo MD *; Van Diest, Ashley Kroon PhD *
doi : 10.1097/MPG.0000000000003577
We have had success treating children with severe rumination syndrome using a multidisciplinary intensive outpatient program (IOP) involving multiple treatment sessions daily. During the coronavirus disease 2019 (COVID-19) pandemic, we temporarily transitioned care to telemedicine.
Multidisciplinary Tiered Care Is Effective for Children and Adolescents With Rumination Syndrome.
Sabella, Julia BA *,+; Kroon Van Diest, Ashley M. PhD +,++; Bali, Neetu MD *; Vaz, Karla MD, MEd *; Yacob, Desale MD *; Di Lorenzo, Carlo MD *; Lu, Peter L. MD, MS *
doi : 10.1097/MPG.0000000000003637
Rumination syndrome (RS) can be challenging to treat and data on treatment outcomes in children are limited. The objective of this study was to evaluate outcomes of children with RS treated with tailored outpatient and inpatient strategies.
Feeding and Swallowing Characteristics of Children With Esophageal Atresia and Tracheoesophageal Fistula.
Maybee, Jennifer OTR, MA CCC-SLP *; Deck, Jacklyn MS, OTR/L *; Jensen, Emily RN, BSN *; Ruiz, Amanda BA *,+; Kinder, Sarah MD *,++; DeBoer, Emily MD *,++
doi : 10.1097/MPG.0000000000003697
This study aimed to characterize feeding/swallowing difficulties in children with esophageal atresia and/or tracheoesophageal fistula (EA/TEF) and evaluate associations among feeding difficulties, pharyngeal dysphagia (PD), and other aerodigestive evaluation findings.
Inter and Intraobserver Variation in Interpretation of Fecal Loading on Abdominal Radiographs.
Yallanki, Narendra MD *,+; Small-Harary, Lesley MD *; Morganstern, Jeffrey MD *; Tobin, Michelle MD *; Milla, Lucia MS ++; Chawla, Anupama MD *
doi : 10.1097/MPG.0000000000003696
The current gold standard for the diagnosis of functional constipation is the ROME IV criteria. European Society for Pediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN) and North American Society for Pediatric Gastroenterology, Hepatology & Nutrition (NASPGHAN) guidelines do not support the use of abdominal X-rays in establishing the diagnosis of constipation. Despite these recommendations, abdominal radiography is frequently performed to diagnose constipation.
Ethical Considerations Within the ESPGHAN Community.
Crespo-Escobar,, Paula PhD *,+; Tapsas, Dimitros MD, PhD ++; Roggero, Paola MD, PhD [S],||; Sokal, Etienne MD [P]; Yahav, Jacob MD #
doi : 10.1097/MPG.0000000000003684
AB There are limited data on ethical issues related to the daily practice of members of the European Society for Pediatric Gastroenterology Hepatology and Nutrition (ESPGHAN). The role of the ESPGHAN Ethics Committee (EC) is to provide advice on such matters to its members.
Systematic Review of Diagnostic Delay for Children With Inflammatory Bowel Disease.
Vernon-Roberts, Angharad PhD *; Aluzaite, Kristina MSc +; Khalilipour, Bahareh MSc +; Day, Andrew S. MB ChB, MD, FRACP, AGAF *
doi : 10.1097/MPG.0000000000003670
Pediatric inflammatory bowel disease (IBD) is a complex inflammatory condition of the gut. Diagnosing IBD involves distinct longitudinal periods from first symptoms to primary care assessment, tertiary care referral, and then endoscopic confirmation.
Diagnosis and Treatment of Iron Deficiency and Anemia in Youth With Inflammatory Bowel Disease.
Smith, Jennifer MS, RD, CSP, LD, LMT *; Jacobson-Kelly, Amanda MD, MSc +; Donegan, Amy MS, APRN *; Boyle, Brendan MD, MPH *,++; Maltz, Ross M. MD *,++; Michel, Hilary K. MD *,++; Dotson, Jennifer L. MD, MPH *,++,[S]
doi : 10.1097/MPG.0000000000003673
Iron deficiency (ID) with and without anemia is prevalent in children and adults diagnosed with inflammatory bowel disease (IBD), but often goes unrecognized. We hypothesized, quality improvement (QI) methodology could increase the screening for and treatment of ID in children newly diagnosed with IBD.
Infusion Appointment Self-Management Among Adolescents With Inflammatory Bowel Disease.
Crume, Bonnie MD *; Mitchell, Paul D. MS +; Fishman, Laurie N. MD *
doi : 10.1097/MPG.0000000000003678
Adolescents and young adults with inflammatory bowel disease (IBD) are in vulnerable positions for lapses in care as they transition from pediatric to adult practices.
Evaluating Transition Readiness: Is Self-Report Valid as the Gold Standard?.
Huang, Jeannie S. MD, MPH *,+; Cruz, Rusvelda MPH *; Kruth, Robin RN +; Parker, Jacob +
doi : 10.1097/MPG.0000000000003680
Determination of transitional readiness is an essential component of delivery of transition services to adolescents and young adults with chronic diseases, including those with inflammatory bowel disease (IBD).
Prevalence and Etiologies of Renal and Urinary Manifestations in a Large Cohort of Children With Inflammatory Bowel Disease.
Cordesse, Anne MD *; Delbet, Jean-Daniel MD +; Lemoine, Anais MD *,++; Dubern, Beatrice MD, PhD *,++; Tounian, Patrick MD, PhD *,++; Lemale, Julie MD *
doi : 10.1097/MPG.0000000000003682
Renal and/or urinary manifestations (RUM) have been reported in pediatric patients with inflammatory bowel disease (IBD) but their incidence is unknown. The aims of this study were to assess the prevalence and causes of these manifestations in children with IBD and determine the causal link with 5-aminosalicylic acid (5-ASA) treatment.
Isolated Terminal Ileitis in Children.
Alper, Arik MD *; Bennett, Aaron MD +; Rottmann, Douglas MD ++; Morotti, Raffaella MD [S]; Escalera, Sandra MD *; Padhye Phatak, Uma MD *; Pashankar, Dinesh S. MD, MBA *
doi : 10.1097/MPG.0000000000003679
AB Isolated terminal ileitis in adults is a well described entity that rarely progresses to Crohn disease (CD), and pediatric literature on this topic is very limited. We describe the prevalence, clinical, endoscopic, histologic, and radiological features, along with long-term outcome of isolated terminal ileitis in our institution.
Intussusception as Rare Presenting Sign of Pediatric Celiac Disease: A Case Series.
Shoshany, Cory BA *; Fahey, Lisa M. MD +
doi : 10.1097/MPG.0000000000003699
AB Intussusception is the most common cause of gastrointestinal obstruction in children and typically presents with acute abdominal pain. Intussusception usually occurs in children under the age of 3 in the ileocecal region.
Mucosal Microbiota Associated With Eosinophilic Esophagitis and Eosinophilic Gastritis.
Furuta, Glenn T. MD *; Fillon, Sophie A. PhD *; Williamson, Kayla M. MS +; Robertson, Charles E. PhD ++; Stevens, Mark J. PhD ++; Aceves, Seema S. MD, PhD [S]; Arva, Nicoleta C. MD, PhD ||; Chehade, Mirna MD, MPH [P]; Collins, Margaret H. MD #; Davis, Carla M. MD **; Dellon, Evan S. MD, MPH ++; Falk, Gary W. MD, MS ++++; Gonsalves, Nirmala MD [S][S]; Gupta, Sandeep K. MD ||||; Hirano, Ikuo MD [S][S]; Khoury, Paneez MD, MHSa [P][P],##; Leung, John MD ***; Martin, Lisa J. PhD +++,++++++; Menard-Katcher, Paul MD [S][S][S]; Mukkada, Vincent A. MD ||||||; Peterson, Kathryn MD [P][P][P]; Spergel, Jonathan M. MD, PhD ###; Wechsler, Joshua B. MD, MS ****; Yang, Guang-Yu MD, PhD ++++; Rothenberg, Marc E. MD, PhD ++++++++; Harris, J. Kirk PhD [S][S][S][S]
doi : 10.1097/MPG.0000000000003685
The aim of the study was to determine the mucosal microbiota associated with eosinophilic esophagitis (EoE) and eosinophilic gastritis (EoG) in a geographically diverse cohort of patients compared to controls.
Untargeted, High-Resolution Metabolomics in Pediatric Eosinophilic Esophagitis.
Sinclair, Elizabeth M. MD *,+; Cohen, Catherine C. PhD, RD ++; Tran, ViLinh MS [S]; Jones, Dean P. PhD [S]; Alvarez, Jessica A. PhD, RD [S]; Kamaleswaran, Rishikesan PhD ||,[P],#; Rad, Milad Ghiasi MS #,**; Kruszewski, Patrice G. DO ||,++; Vos, Miriam B. MD, MSPH ||,++
doi : 10.1097/MPG.0000000000003693
Eosinophilic esophagitis (EoE) is an inflammatory disease of unclear etiology. The aim of this study was to use untargeted plasma metabolomics to identify metabolic pathway alterations associated with EoE to better understand the pathophysiology.
Splenic Stiffness Is the Best Predictor of Clinically Significant Varices in Children With Portal Hypertension.
Upadhyay, Piyush MD, DM *; Khanna, Rajeev MD *; Sood, Vikrant MD, DM *; Lal, Bikrant Bihari MD, DM *; Patidar, Yashwant MD *; Alam, Seema MD *
doi : 10.1097/MPG.0000000000003674
We studied splenic stiffness measurement (SSM) by transient elastography (TE) and portal hemodynamics parameters (PHDp) on Doppler as predictors of clinically significant varices (CSV) in children.
Pediatric Hepatitis C Quality Improvement Project Improves Healthcare Access.
Vallabhan, Monique K. DNP, FNP-BC *; Castillo, Ricardo MD +; Roldan, Patricia MS *; Rhoades, Natalie RN +; Kong, Alberta S. MD, MPH *; Jimenez, Elizabeth Y. PhD, RDN *
doi : 10.1097/MPG.0000000000003690
Incidence of hepatitis C virus (HCV) infection is increasing in women of reproductive age, leading to increased prevalence of HCV infection in children via vertical transmission.
Length of Bowel Rest Does Not Predict Gastrojejunostomy Tube-Associated Intussusception Recurrence.
Abebe, Abel Tsehay MD *; Worede, Fikadu MD *; Elsingergy, Mohamed MD *; Cahill, Anne Marie MBBch, BAO +; Acord, Michael R. MD +
doi : 10.1097/MPG.0000000000003692
One potential treatment for gastrojejunostomy (GJ) tube-related intussusception is bowel rest, whereby the GJ tube is replaced with a gastrostomy tube. The aim of this study was to determine whether bowel rest length was associated with decreased risk of re-intussusception.
Sociodemographic Differences of Hospitalization and Associations of Resource Utilization for Failure to Thrive.
Wu, Allison J. MD, MPH *; Du, Nan MD *; Chen, Thomas Yen-Ting MD, MPH +; Fiechtner, Lauren MD, MPH ++,[S]
doi : 10.1097/MPG.0000000000003694
This study examines the sociodemographic differences between elective and nonelective admissions for failure to thrive (FTT). We investigate associations between admission type and hospital resource utilization, including length of stay and feeding tube placement.
Nutritional Management of Infants With a Giant Ruptured Omphalocele: Clinical Observations From a Single Institution Case Series.
Burke, Shannon RD, CSP *; Laverde, Ruth BS +; Klarich, Mary Kate NP, MSN *; Vu, Lan Tuyet MD, MAS ++
doi : 10.1097/MPG.0000000000003650
AB The nutritional requirements of neonates with congenital abdominal wall defects (AWDs) remain poorly described. In particular, there is a lack of literature on the calorie, protein, and micronutrient needs of those with AWD.
The North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition Position on the Role of the Registered Dietitian Nutritionist in the Care of the Pediatric Patient With Chronic Gastrointestinal Diseases.
Walia, Cassandra L. S. MS, RD, CD *; Cerezo, Carolina S. MD, FAAP +; Smith, Amber MBA, RD, CD ++; Turner, Justine MBBS, FRACP, PhD [S]; Moses, Jonathan MD ||; Vermilyea, Sarah MS, RD, CSP, LD, CNSC [P]; Gupta, Sandeep K. MD #,**; Verma, Ritu MD ++
doi : 10.1097/MPG.0000000000003695
AB The optimization of nutrition is essential for the growth and development of all children, including those with gastrointestinal (GI) conditions that can variably affect nutrient intake, absorption, or metabolism.
Chanarin-Dorfman Syndrome: A Neutral Lipid Storage Disease With Ichthyosis and Liver Cirrhosis.
Rajasekaran, Vivek MBBS *; McFarlane, Jeannette MBChB, FRCPath +; Purvis, Diana MBChB, MRCPCH, FRACP, FNZDS ++; Prestidge, Timothy MBChB, FRACP, FRCPA [S]; Evans, Helen MBChB, MRCP, FRACP *
A Solution to Difficult Esophageal Button Battery Removals.
Hudson, Alexandra S. MD, FRCPC *; Huynh, Hien Q. MBBS, FRCPC *
Transanal Irrigation in Children With Functional Constipation: Doing It the Right Way for the Right Indication.
Bolia, Rishi MD, DM *
Reply to: Transanal Irrigation in Children With Functional Constipation: Doing It the Right Way for the Right Indication.
Baaleman, Desiree F. MD *,+; Wegh, Carrie A.M. MSc, PhD *,+,++; Hoogveld, Maxime T.A. MD *; Benninga, Marc A. MD, PhD *; Koppen, Ilan J.N. MD, PhD *
Severe Hepatitis in Children Likely Caused by HAdV-41 Following SARS-CoV-2 Induced Mitochondrial Permeability Transition.
Mohammed, Fahad S. BS *; Karnsakul, Wikrom MD, FAASLD +; Mohammed, Suneel MD ++; Russo, Mark W. MD, FAASLD [S]
Reply to: Severe Hepatitis in Children Likely Caused by HAdV-41 Following SARS-CoV-2.
Cooper, Shiri *,+; Waisbourd-Zinman, Orith *,+
