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Screening and Interventions for Glaucoma and Eye Health Through Telemedicine (SIGHT) Studies
De Moraes, Carlos Gustavo MD, PhD, MPH*,†; Hark, Lisa A. PhD, RD, MBA*,†; Saaddine, Jinan MD, MPH
doi : 10.1097/IJG.0000000000001782
May 2021 - Volume 30 - Issue 5 - p 369-370
No Abstract
Alabama Screening and Intervention for Glaucoma and Eye Health Through Telemedicine (AL-SIGHT): Study Design and Methodology
Rhodes, Lindsay A. MD, MSPH*; Register, Shilpa OD, PhD*; Asif, Irfan MD†; McGwin, Gerald Jr MS, PhD*,‡; Saaddine, Jinan MD, MPH§; Nghiem, Van Thi Ha PhD?; Owsley, Cynthia PhD, MSPH*; Girkin, Christopher A. MD, MSPH*
doi : 10.1097/IJG.0000000000001794
May 2021 - Volume 30 - Issue 5 - p 371-379
This paper presents the methods and protocol of a community-based telemedicine program to identify glaucoma and other eye diseases.
Michigan Screening and Intervention for Glaucoma and Eye Health Through Telemedicine (MI-SIGHT): Baseline Methodology for Implementing and Assessing a Community-based Program
Newman-Casey, Paula A. MD, MS*,†; Musch, David C. PhD, MPH*,†,‡,§; Niziol, Leslie M. MA*; Elam, Angela R. MD*; Zhang, Jason MD*; Moroi, Sayoko E. MD, PhD*,‡; Johnson, Leroy MD?; Kershaw, Martha MD¶; Saadine, Jinan MD, MPH#; Winter, Suzanne MS*; Woodward, Maria A. MD, MS*,†
doi : 10.1097/IJG.0000000000001812
May 2021 - Volume 30 - Issue 5 - p 380-387
The Michigan Screening and Intervention for Glaucoma and eye Health through Telemedicine (MI-SIGHT) program leverages community-engaged research, telemedicine, and health coaching to overcome key logistical and psychosocial barriers to improve glaucoma screening in underserved communities.
Manhattan Vision Screening and Follow-up Study in Vulnerable Populations (NYC-SIGHT): Design and Methodology
Hark, Lisa A. PhD, RD*,†; Kresch, Yocheved S. OD, MS*,†; De Moraes, Carlos Gustavo MD*,†; Horowitz, Jason D. MD*,†; Park, Lisa MD*,†; Auran, James D. MD*,†; Gorroochurn, Prakash PhD‡; Stempel, Stella PhD, LCSW†; Maruri, Stefania C. BS†; Stidham, Elizabeth M. BS†; Banks, Aisha Z. BA†; Saaddine, Jinan B. MD, MPH§; Lambert, Bianca C. MD, MS?; Pizzi, Laura T. PharmD, MPH¶; Sapru, Saloni PhD#; Price, Simani PhD#; Williams, Olajide A. MD**; Cioffi, George A. MD*,†; Liebmann, Jeffrey M. MD*,†
doi : 10.1097/IJG.0000000000001795
May 2021 - Volume 30 - Issue 5 - p 388-394
The Manhattan Vision Screening and Follow-up Study in Vulnerable Populations is a 5-year prospective, cluster-randomized study to improve detection and management of glaucoma and other eye diseases in vulnerable populations living in affordable housing developments.
The Effect of Direct Health Education on the Uptake of Screening by First Degree Relatives of Glaucoma Patients in Nigeria
Ogunleye, Olakunle MD, FMCOph*; Olawoye, Olusola MD, FWACS*,†; Sarimiye, Tarela MD, FWACS*,†; Bekibele, Charles MD, FWACS*,†; Ashaye, Adeyinka MD, FWACS*,†
doi : 10.1097/IJG.0000000000001769
May 2021 - Volume 30 - Issue 5 - p 395-401
First degree relatives (FDRs) of glaucoma patients are more likely to present for screening when they are directly contacted and educated by health workers on the phone compared with when they are only invited by their relative with glaucoma.
Facilitators and Barriers to Glaucoma Screening Identified by Key Stakeholders in Underserved Communities: A Community-engaged Research Approach
Ballouz, Dena BS*; Cho, Juno MA*; Woodward, Maria A. MD, MS*,†; Elam, Angela R. MD*; Musch, David C. PhD, MPH*,†,‡; Zhang, Jason MD*; Moroi, Sayoko E. MD, PhD§; Johnson, Leroy MD?; Cederna, Jean MD¶; Newman-Casey, Paula A. MD, MS*,†
doi : 10.1097/IJG.0000000000001756
May 2021 - Volume 30 - Issue 5 - p 402-409
Community-engaged research (CER) enables researchers to identify community-specific barriers and facilitators to program implementation. Broadly applicable barriers to glaucoma care, such as Cost, Transportation, and Trust, and community-specific barriers, such as Language and Convenience/Access, were identified.
Effects of Wearing the Elevation Training Mask During Low-intensity Cycling Exercise on Intraocular Pressure
Vera, Jes?s PhD*; Jiménez, Raimundo PhD*; Redondo, Beatr?z PhD*; Perez-Castilla, Alejandro PhD†; Garc?a-Ramos, Amador PhD†,‡
doi : 10.1097/IJG.0000000000001807
May 2021 - Volume 30 - Issue 5 - p e193-e197
Low-intensity aerobic exercise is recommended to reduce intraocular pressure (IOP) levels. However, this effect depends on several factors. We found that using an elevation training mask (ETM) during low-intensity aerobic exercise causes an IOP rise.
A Scoping Review of Process Indicators for Measuring Quality of Care in Glaucoma
Iorio-Aranha, Flavio MD, MSc*,†; Peleteiro, B?rbara MSc, PhD*,‡,§; Rocha-Sousa, Amândio MD, PhD, FEBO?,¶; Azevedo, Ana MD, PhD*,‡,§; Barbosa-Breda, Jo?o MD, PhD
doi : 10.1097/IJG.0000000000001825
May 2021 - Volume 30 - Issue 5 - p e198-e204
There are no standardized process quality indicators (QIs) in glaucoma care. Although they can be inferred from guidelines and trials, they should be designed and standardized to allow better assessment of the quality of care.
Depression and Severity of Glaucoma Among Older Adults in Urban and Suburban Areas
Tharmathurai, Sangeetha MMed*,†,‡; Muhammad-Ikmal, Mohamad K. MBBCh*,†,§; Razak, Asrenee A. PhD?; Che-Hamzah, Jemaima PhD¶; Azhany, Yaakub MMed*,†; Fazilawati, Qamaruddin MSurg‡; Liza-Sharmini, Ahmad T. MBBS, MMed (Ophthal), PhD*
doi : 10.1097/IJG.0000000000001830
May 2021 - Volume 30 - Issue 5 - p e205-e212
Depression increases with severity of visual field defect in older adults with primary open-angle glaucoma (POAG).
Evaluation of Retinal Nerve Fiber Layer, Ganglion Cell-Inner Plexiform Layer, and Optic Nerve Head in Glaucoma Suspects With Varying Myopia
Miller, Gregg D. BA*; Abu-Qamar, Omar MD†; Salim, Sarwat MD, FACS†
doi : 10.1097/IJG.0000000000001834
May 2021 - Volume 30 - Issue 5 - p e213-e221
Myopic glaucoma suspects, particularly with high myopia, experience thinning of nontemporal parameters of retinal nerve fiber layer (RNFL) and ganglion cell-inner plexiform layer (GCIPL), without change in optic nerve head (ONH) parameters.
Detection of Primary Angle Closure Glaucoma Progression by Optical Coherence Tomography
Kurysheva, Natalia I. Med.ScD; Lepeshkina, Lyudmila V. MD
doi : 10.1097/IJG.0000000000001829
May 2021 - Volume 30 - Issue 5 - p 410-420
To compare the role of spectral-domain optical coherence tomography (SD-OCT) in regard to retinal nerve fiber layer (RNFL) and ganglion cell complex (GCC) assessment in the detection of primary angle-closure glaucoma (PACG) and primary open-angle glaucoma (POAG) progression.
Semiautomated Assessment of Anterior Segment Structures in Pediatric Glaucoma Using Quantitative Ultrasound Biomicroscopy
Alexander, Janet L. MD*; Maripudi, Snehaa MD*; Kannan, Karun BS†; Drechsler, Jennifer BS*; Levin, Moran R. MD*; Saeedi, Osamah J. MD*; Kaleem, Mona MD‡; Bazemore, Marlet MD§; Karwoski, Bethany MD§; Martinez, Camilo COT§; Jaafar, Mohamad MD§; Madigan, William P. MD
doi : 10.1097/IJG.0000000000001809
May 2021 - Volume 30 - Issue 5 - p e222-e226
The study was a prospective observational study comparing semiautomated to manual quantitative ultrasound biomicroscopy image analysis among 82 images from 41 eyes of 32 subjects (21 controls and 11 glaucoma) enrolled in the Pediatric Anterior Segment Imaging Innovation Study. Intraclass correlation coefficients and correlation coefficients were >0.8 for all parameters, and comparison of respective analysis speed was 7 times faster for the semiautomated method compared with manual image quantification.
Comparison of Tono-Pen Avia and Handheld Applanation Tonometry in Primary Congenital Glaucoma
Cronemberger, Sebasti?o MD, PhD; Veloso, Artur W. MD
doi : 10.1097/IJG.0000000000001820
May 2021 - Volume 30 - Issue 5 - p e227-e230
Tono-Pen AVIA (TPA) intraocular pressure (IOP) values are different from those taken with handheld Goldmann applanation tonometer (GAT) in primary congenital glaucoma (PCG). These differences indicate both tonometers cannot be used interchangeably for measuring IOP in PCG.
Evaluating the Relationship of Intraocular Pressure and Anterior Chamber Volume With Use of Prostaglandin Analogues
Scott, Jessica A. MD, MS*; Roberts, Cynthia J. PhD*,†; Mahmoud, Ashraf M. BS*,†; Jain, Shelly Gupta MD*
doi : 10.1097/IJG.0000000000001736
May 2021 - Volume 30 - Issue 5 - p 421-427
In this prospective study, naive prostaglandin use in primary open-angle glaucoma was associated with scleral biomechanical alteration and intraocular pressure (IOP) measuring errors.
Efficacy and Safety of Ultrasound Cycloplasty for Refractory Glaucoma: A 3-Year Study
Rouland, Jean-François MD, FEBO*; Aptel, Florent MD, PhD†
doi : 10.1097/IJG.0000000000001796
May 2021 - Volume 30 - Issue 5 - p 428-435
Ultrasound cycloplasty (UCP) treatment using high-intensity focused ultrasound is an effective and safe therapy to reduce intraocular pressure (IOP) in patients with refractory glaucoma over a 3-year period.
Comparing the Effect of Lens Extraction With Endocycloplasty to Lens Extraction Alone in Eyes With Plateau Iris Configuration: Pilot Study
Lu, Monica BA*; Chuang, Alice Z. PhD*; Feldman, Robert M. MD*,†
doi : 10.1097/IJG.0000000000001793
May 2021 - Volume 30 - Issue 5 - p 436-443
Lens extraction with endocycloplasty (LE/ECPL) results in greater angle deepening than LE alone in plateau iris eyes. This study directly compares an LE/ECPL treatment group with a control group.
Efficacy and Safety of the Susanna Glaucoma Drainage Device After 1 Year of Follow-up
Susanna, Fernanda N. MB*; Susanna, Bianca N. MB†; Susanna, Carolina N. MB†; Nicolela, Marcelo T. PhD, MD‡; Susanna, Remo Jr PhD, MD*
doi : 10.1097/IJG.0000000000001802
May 2021 - Volume 30 - Issue 5 - p e231-e236
This study found a rate of failure of 13.6% of the new Susanna Glaucoma Drainage Device (SGDD) after 1 year of follow-up. Severe complications occurred in 1 patient (4.5%).
Lower Success in Trabeculectomies in Exfoliation Compared With Primary Open-angle Glaucoma Patients in Sweden
Ayala, Marcelo MD, PhD
doi : 10.1097/IJG.0000000000001818
May 2021 - Volume 30 - Issue 5 - p e237-e245
In a Sweden-based study, a lower success rate in exfoliation than in open-angle glaucoma patients was found in a 5-year follow-up after trabeculectomy.
Changes in Corneal Biomechanics and Glaucomatous Visual Field Loss
Chan, Eric MD; Yeh, Kaileen MD; Moghimi, Sasan MD; Proudfoot, James MSc; Liu, Xiongfei MD; Zangwill, Linda PhD; Weinreb, Robert N. MD
doi : 10.1097/IJG.0000000000001819
May 2021 - Volume 30 - Issue 5 - p e246-e251
A lower baseline corneal hysteresis and a decrease in corneal resistance factor (CRF) over time are associated with higher risk of visual field progression in glaucomatous and glaucoma suspect eyes.
Corneal Properties in Primary Open-angle Glaucoma Assessed Through Scheimpflug Corneal Topography and Densitometry
Molero-Senosiain, Mercedes MD; Morales-Fernandez, Laura MD, PhD; Saenz-Frances, Federico MD, PhD; Perucho-Gonzalez, Lucia MD, PhD; Garc?a-Bella, Javier MD, PhD; Garcia Feijoo, Julian MD, PhD; Martinez-de-la-Casa, Jose M. MD, PhD
doi : 10.1097/IJG.0000000000001770
May 2021 - Volume 30 - Issue 5 - p 444-450
The purpose of this study was to compare corneal topography and densitometry measurements in patients with primary open-angle glaucoma (POAG) and healthy subjects.
The Relationship Between Corneal Biomechanics and Intraocular Pressure Dynamics in Patients Undergoing Intravitreal Injection
Dackowski, Evan K. BA; Moon, Jee-Young PhD; Wang, Jessie MD; Shrivastava, Anurag MD; Schultz, Jeffrey S. MD
doi : 10.1097/IJG.0000000000001833
May 2021 - Volume 30 - Issue 5 - p 451-458
A higher “corneal resistance factor” (CRF) was associated with greater intraocular pressure (IOP) elevation after intravitreal injection of bevacizumab. Both higher “corneal hysteresis” (CH) and CRF were associated with more rapid IOP recovery postinjection.
Safety of 3 Tesla Magnetic Resonance Imaging on iStent Implants: An Ex-Vivo Study
Ayalon, Anfisa MD*,†; Fanadka, Feda MD†,‡; Belkin, Avner MD*,†; Burgansky, Zvia MD*,†; Moisseiev, Elad MD*,†
doi : 10.1097/IJG.0000000000001801
May 2021 - Volume 30 - Issue 5 - p e252-e255
Our study shows that iStent implant does not cause significant image artifacts, heating, or displacement during magnetic resonance imaging (MRI) scan. This device can be safely used in patients undergoing MRI scans using 3 Tesla (3T) machines.
COVID-19–related Ocular Hypertension Secondary to Anterior Uveitis as Part of a Multisystemic Inflammatory Syndrome
Alonso, Ruiz S. MD, PhD*; Alonso, Fabio O.M. PhD†; Fernandes, Bruno F. MD, PhD‡; Ecard, Virginia O. MD§; Ventura, Marcelo P. MD, PhD*
doi : 10.1097/IJG.0000000000001835
May 2021 - Volume 30 - Issue 5 - p e256-e258
It is the consensus of the medical community that ocular complications associated with Coronavirus Disease 2019 (COVID-19) are mild, self-limiting, and there are no reports to date of a sight-threatening event. We report a patient with a systemic inflammatory syndrome in the context of COVID-19, with ophthalmological (uveitis), dermatological (erythema and skin nodules), and cardiovascular (edema) manifestations. The anterior uveitis led to an increase in the intraocular pressure that failed to respond to clinical treatment and prompted a surgical intervention to save the vision. To the best of our knowledge, this is the first report of a COVID-19–related ocular hypertension. Timely surgical intervention was key to save the vision in the patient’s only eye.
Bilateral Acute Angle Closure in a Pediatric Patient Taking Lisdexamfetamine Dimesylate (Vyvanse)
Davanian, Arash M. DO*,†; Fitzpatrick, John C. MD*,†; Tran, Duy P. MD†; Korducki, John P. MD†; Groth, Sylvia L. MD*,†
doi : 10.1097/IJG.0000000000001826
May 2021 - Volume 30 - Issue 5 - p e259-e261
Attention-deficit/hyperactivity disorder is commonly treated with amphetamines as first line therapy. Rare case reports have shown amphetamines are associated with open angle glaucoma. We report a rare case of a 14-year-old male who presented with bilateral acute angle closure presumed to be related to his use of lisdexamfetamine dimesylate (Vyvanse). The patient’s medication was discontinued which resulted in complete resolution of angle closure.
Bilateral Ocular Ischemic Syndrome in the Setting of Chronic Angle Closure Glaucoma
Naravane, Ameay V. MD*; Mallory, Paul W. MD†; Boysen, Jess MD†; Koozekanani, Dara MD, PhD†; Lee, Michael S. MD†
doi : 10.1097/IJG.0000000000001767
May 2021 - Volume 30 - Issue 5 - p e262-e264
We report novel case of a 57-year-old woman who developed bilateral ocular ischemic syndrome in the setting of chronic angle closure glaucoma without associated angle neovascularization. Detailed is a course in which markedly prolonged, elevated intraocular pressure led to significantly reduced arterial perfusion at the level of the central retinal artery, leading to the clinical picture of ocular ischemic syndrome.
Acute Angle Closure in Knobloch Syndrome
Wawrzynski, James MA(Cantab), MB, BChir*; Than, Jonathan MA(Cantab), MB, BChir†; Gillam, Matthew FRCOphth†; Foster, Paul J. PhD, FRCS(Ed)‡
doi : 10.1097/IJG.0000000000001781
May 2021 - Volume 30 - Issue 5 - p e265-e268
We report cases of acute angle closure in 2 young highly myopic siblings with Knobloch syndrome. To our knowledge, this is the first report of acute angle closure in Knobloch syndrome. Both patients were homozygous for a likely pathogenic variant in COL18A1. Both responded to treatment with cyclophotocoagulation and remained stable despite declining or being medically unfit for clear lens extraction. We argue that the recent implication of heterozygous mutations in COL18A1 in familial angle closure supports the argument that acute angle closure in these 2 patients was likely to be a thus far unreported feature of Knobloch syndrome. In addition, these cases also support the hypothesis that pathogenic variants in COL18A1 may be a risk factor for acute angle closure.
Aqueous Misdirection After Trabeculectomy in a Down Syndrome Patient With Angle-closure Glaucoma
Fox, Austin R. MD*; Alward, Wallace L.M. MD*,†; Fingert, John H. MD, PhD*,†
doi : 10.1097/IJG.0000000000001831
May 2021 - Volume 30 - Issue 5 - p e269-e270
Down syndrome is a genetic disease caused by trisomy of chromosome 21 that is characterized by numerous systemic abnormalities including intellectual disability, stereotypical facies, and congenital heart malformations. Ocular abnormalities are commonly seen with Down syndrome including corneal disease (keratoconus), refractive error, and atypical irides (Brushfield spots). We report the first case of aqueous misdirection in a patient with Down syndrome after trabeculectomy. Patients with Down syndrome often have small, hyperopic eyes with narrow iridocorneal angles and may be at increased risk for aqueous misdirection associated with surgical procedures. Awareness of this risk may aid surgical planning and postoperative management.
An Infectious Cause of Congenital Pupillary-Iris-Lens Membrane With Secondary Angle Closure Glaucoma in an Infant
Maheshwari, Devendra MD*; Rao, Sanjana DNB*; Pawar, Neelam MS†; Kadar, Mohideen A. DNB*; Ramakrishnan, Rengappa MS*
doi : 10.1097/IJG.0000000000001726
May 2021 - Volume 30 - Issue 5 - p e271-e273
The aim of the study was to report an infectious cause of congenital pupillary-iris-lens membrane with secondary angle closure glaucoma in an infant.
Letter to the Editor: Acute Intraocular Pressure Responses to Reading: The Influence of Body Position
Singla, Ekta MS; Ichhpujani, Parul MS
doi : 10.1097/IJG.0000000000001821
May 2021 - Volume 30 - Issue 5 - p e274
Response to Letter to the Editor: Acute Intraocular Pressure Responses to Reading: The Influence of Body Position
Vera, Jes?s PhD*; Redondo, Beatriz MS*; Molina, Rubén MS*; C?rdenas, David PhD†; Jiménez, Raimundo PhD*
doi : 10.1097/IJG.0000000000001822
May 2021 - Volume 30 - Issue 5 - p e274-e275
