doi : 10.1001/jama.2022.17927
November 15, 2022, Vol 328, No. 19, Pages 1889-1988
Naomi E. Hammond, RN, PhD1,2; John Myburgh, MD, PhD1,3; Ian Seppelt, MD1,4; Tessa Garside, MBBS, PhD1,2; Ruan Vlok, MBBS2; Sajeev Mahendran, MD2; Derick Adigbli, MD, PhD1,2; Simon Finfer, MD1,5; Ya Gao, MM6,7; Fiona Goodman, BN1; Gordon Guyatt, MD, PhD8; Joseph Alvin Santos, PhD9; Balasubramanian Venkatesh, MD1,10; Liang Yao, MM7; Gian Luca Di Tanna, PhD9,11; Anthony Delaney, MBBS, PhD1,2
doi : 10.1001/jama.2022.19709
Importance The effectiveness of selective decontamination of the digestive tract (SDD) in critically ill adults receiving mechanical ventilation is uncertain.
James P. Pirruccello, MD1,2,3,4,5; Honghuang Lin, PhD6,7,8; Shaan Khurshid, MD, MPH1,2,3,4; Mahan Nekoui, MD3,4,9; Lu-Chen Weng, PhD2,3; Ramachandran S. Vasan, MD6,8,10,11; Eric M. Isselbacher, MD1,4,12; Emelia J. Benjamin, MD, ScM6,8,10,11; Steven A. Lubitz, MD, MPH1,2,3,4,13,14; Mark E. Lindsay, MD, PhD1,2,3,4,12; Patrick T. Ellinor, MD, PhD1,2,3,4,13
doi : 10.1001/jama.2022.19701
Importance Ascending thoracic aortic disease is an important cause of sudden death in the US, yet most aortic aneurysms are identified incidentally.
Ryan Howard, MD, MS1; Jie Yang, PhD2; Jyothi Thumma, MPH2; Anne Ehlers, MD, MPH1; Sean O’Neill, MD, PhD1; Dana Telem, MD, MPH1; Justin B. Dimick, MD, MPH1
doi : 10.1001/jama.2022.14843
Michael Liu, MPhil1; Rishi K. Wadhera, MD, MPP, MPhil2
doi : 10.1001/jama.2022.15106
doi : 10.1001/jama.2022.20304
Importance Current prevalence of obstructive sleep apnea (OSA) in the US is not well established; however, based on cohort and survey data, in 2007-2010 the estimated prevalence of at least mild OSA (defined as an apnea-hypoxia index [AHI] ≥5) plus symptoms of daytime sleepiness among adults aged 30 to 70 years was 14% for men and 5% for women, and the estimated prevalence of moderate to severe OSA (defined as AHI ≥15) was 13% for men and 6% for women.
Cynthia Feltner, MD, MPH1,2,3; Ina F. Wallace, PhD1,4; Shannon Aymes, MD, MPH2; Jennifer Cook Middleton, PhD1,3; Kelli L. Hicks, MD, MPH5; Manny Schwimmer, MPH1,6; Claire Baker1,3; Casey P. Balio, PhD7; Daniel Moore, MPH2; Christiane E. Voisin, MSLS1,6; Daniel E. Jonas, MD, MPH1,6
doi : 10.1001/jama.2022.18357
Importance Obstructive sleep apnea (OSA) is associated with adverse health outcomes.
G. Caleb Alexander, MD, MS1,2; Omar Mansour, MHS3
doi : 10.1001/jama.2022.19667
I. Glenn Cohen, JD1; Eli Y. Adashi, MD, MS2; Seema Mohapatra, JD, MPH3
doi : 10.1001/jama.2022.19471
Philip P. Goodney, MD, MS1,2; Grace Wang, MD, MSCE3
doi : 10.1001/jama.2022.9164
Daniel J. Gottlieb, MD, MPH1,2,3
doi : 10.1001/jama.2022.20670
Bridget M. Kuehn, MSJ
doi : 10.1001/jama.2022.19233
Rita Rubin, MA
doi : 10.1001/jama.2022.18478
Rita Rubin, MA
doi : 10.1001/jama.2022.18479
Howard D. Larkin
doi : 10.1001/jama.2022.18474
Howard D. Larkin
doi : 10.1001/jama.2022.18475
Howard D. Larkin
doi : 10.1001/jama.2022.18476
Howard D. Larkin
doi : 10.1001/jama.2022.20720
Christina Yek, MD1; Sameer S. Kadri, MD, MS1
doi : 10.1001/jama.2022.16729
Jeremy Samuel Faust, MD, MS1; Benjamin Renton, BA2; Chengan Du, PhD3
doi : 10.1001/jama.2022.16726
Nikolaos Vlachadis, MD, DMD, MPH, MSc, DSc1; Nikolaos Vrachnis, MD, PhD2
doi : 10.1001/jama.2022.16732
Patricia L. Kavanagh, MD1; Titilope Fasipe, MD, PhD2; Ted Wun, MD3
doi : 10.1001/jama.2022.16735
Xavier Moisset, MD, PhD1; Nadine Attal, MD, PhD2; Daniel Ciampi de Andrade, MD, PhD3
doi : 10.1001/jama.2022.16940
Angela Renne, BS1; Shuhan He, MD2; Jarone Lee, MD, MPH3
doi : 10.1001/jama.2022.16943
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