Journal of the Neurological Sciences




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سفارش

Clinical milestones as triggers for palliative care intervention in progressive Supranuclear palsy and multiple system atrophy

Robin Bessemer a, Alla Iansavichene b, Mary E. Jenkins a, Elizabeth Finger a, Teneille E. Gofton

doi : 10.1016/j.jns.2023.120614

Volume 448, 15 May 2023, 120614

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Participation by patients from low- and middle-income countries (LMICs) in trial evidence supporting secondary stroke prevention guideline recommendations

Priscilla Abrafi Opare-Addo a, Fred Stephen Sarfo a,b,*, Patrick Opoku Berchie a, Minas Aikins a, Bruce Ovbiagele

doi : 10.1016/j.jns.2023.120641

Volume 448, 15 May 2023, 120641

One out of every four strokes is a highly preventable recurrent stroke. However, while low-and-middle-income countries (LMICs) experience a disproportionate global burden of stroke, individuals in these regions seldomly participate in pivotal clinical trials, which form the basis for international expert consensus guideline recommendations.

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Plasma growth differentiation factor − 8 / Myostatin level as prognostic biomarker of patients with ischemic stroke and acute revascularization therapy. PARADISE study

Pauline Jakubina a,b, Alexandre Meloux b, Gauthier Duloquin a,b, Serge Aho c, Catherine Vergely b, Yannick B �ejot

doi : 10.1016/j.jns.2023.120611

Volume 448, 15 May 2023, 120611

Identifying biological markers of ischemic stroke (IS) is an important research approach to develop innovative therapeutic strategies. This study aimed to assess the association between plasma Growth Differentiation Factor-8 (GDF-8)/Myostatin levels and outcome of IS patients.

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Cortical atrophy and leukoaraiosis, imaging markers of cerebrovascular small vessel disease, are associated with driving behavior changes among cognitively normal older adults

Ganesh M. Babulal a,b,c,d,*, Ling Chen e, David B. Carr f, Ann M. Johnson g, Joshua S. Shimony h, Jason Doherty a, Samantha Murphy a, Alexis Walker a, Hailee Domash a, Russ Hornbeck h, Sarah Keefe h, Shaney Flores h, Cyrus A. Raji a,h, John C. Morris a,b,i, Beau M. Ances a,h,i, Tammie L.S. Benzinger

doi : 10.1016/j.jns.2023.120616

Volume 448, 15 May 2023, 120616

Cerebral small vessel disease (CSVD) as measured by cortical atrophy and white matter hyperintensities [leukoaraiosis], captured via magnetic resonance imaging (MRI) are increasing in prevalence due to the growth of the aging population and an increase in cardiovascular risk factors in the population. CSVD impacts cognitive function and mobility, but it is unclear if it affects complex, functional activities like driving.

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Altered visual conscious awareness in patients with vestibular dysfunctions; a cross-sectional observation study

Mishaal Sharif a,1, Yougan Saman a,b,1, Rose Burling a, Oliver Rea a, Rakesh Patel c, Douglas J.K. Barrett a, Peter Rea b, Amir Kheradmand d,e,*,1, Qadeer Arshad

doi : 10.1016/j.jns.2023.120617

Volume 448, 15 May 2023, 120617

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Clinical, radiological, and molecular analyses of neuronal intranuclear inclusion disease with polyglycine inclusions

Minori Furuta a, Masayuki Sato a, Hiroo Kasahara a, Setsuki Tsukagoshi a, Kimitoshi Hirayanagi a,b, Yukio Fujita a, Eriko Takai a, Yuko Aihara c, Koichi Okamoto d, Yoshio Ikeda

doi : 10.1016/j.jns.2023.120618

Volume 448, 15 May 2023, 120618

Neuronal intranuclear inclusion disease (NIID) is a clinically complex neurological disorder that appears sporadically or autosomally. Expansions of intronic GGC trinucleotide repeats in the NOTCH2 N-terminal-like C (NOTCH2NLC) gene cause NIID.

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Digital health metrics reveal upper limb impairment profiles in ARSACS

Christoph M. Kanzler a,b,*, Isabelle Lessard c, Roger Gassert a,b, Bernard Brais d, Cynthia Gagnon c,e,1, Olivier Lambercy

doi : 10.1016/j.jns.2023.120621

Volume 448, 15 May 2023, 120621

Adults with autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS) often present with reduced upper limb coordination affecting their independence in daily life. Previous studies in ARSACS identified reduced performance in clinical assessments requiring fine and gross dexterity as well as prehension.

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Risk factors for developing dyskinesia among Parkinson's disease patients with wearing-off: J-FIRST

Takayasu Mishima a, Shih-Wei Chiu b, Hidemoto Saiki c,1, Takuhiro Yamaguchi b, Yasushi Shimo d,2, Tetsuya Maeda e,3, Hirohisa Watanabe f,4, Kenichi Kashihara g,5, Masahiro Nomoto h,6, Nobutaka Hattori d, Yoshio Tsuboi a,*, on behalf of the J-FIRST Group

doi : 10.1016/j.jns.2023.120619

Volume 448, 15 May 2023, 120619

Dyskinesia frequently occurs during long-term treatment with levodopa in patients with Parkinson's disease (PD) and impacts quality of life. Few studies have examined risk factors for developing dyskinesia in PD patients exhibiting wearing-off. Therefore, we investigated the risk factors and impact of dyskinesia in PD patients exhibiting wearing-off.

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Vitamin K antagonists but not non-vitamin K antagonists in addition on antiplatelet therapy should be associated with increase of hematoma volume and mortality in patients with intracerebral hemorrhage: A sub-analysis of PASTA registry study

Koichi Nomura a,b,*, Satoshi Suda a, Arata Abe c, Yasuyuki Iguchi d, Yoshiki Yagita e, Takao Kanzawa f,g, Seiji Okubo h, Shigeru Fujimoto i, Kazumi Kimura a, on behalf of the PASTA study group

doi : 10.1016/j.jns.2023.120643

Volume 448, 15 May 2023, 120643

Prior concomitant use of vitamin K antagonists (VKAs) and antiplatelet (AP) therapy increase the hematoma volume and mortality compared with VKA monotherapy in patients with intracranial hemorrhage (ICH). However, the prior concomitant use of non-vitamin K oral antagonists (NOACs) and AP has not been clarified.

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Development of a stroke risk score with MRI asymptomatic brain lesions attributes to evaluate prognostic vascular events

Kenichi Iwasa a,*, Keiichi Onoda b, Masahiro Takamura a, Hiroyuki Takayoshi c, Shingo Mitaki a, Shuhei Yamaguchi c, Atsushi Nagai

doi : 10.1016/j.jns.2023.120642

Volume 448, 15 May 2023, 120642

The use of a combination of stroke predictors, such as clinical factors and asymptomatic lesions on brain magnetic resonance imaging (MRI), may improve the accuracy of stroke risk prediction. Therefore, we attempted to develop a stroke risk score for healthy individuals.

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Safety of recanalization therapy in patients with acute ischemic stroke on direct oral anticoagulants: A sub-analysis of PASTA registry study

Satoshi Suda a,*, Arata Abe b,c, Yasuyuki Iguchi d, Yoshiki Yagita e, Takao Kanzawa f,g, Seiji Okubo c, Shigeru Fujimoto h, Yu Kono i, Kazumi Kimura a, on behalf of PASTA Investigators

doi : 10.1016/j.jns.2023.120639

Volume 448, 15 May 2023, 120639

The safety of intravenous recombinant tissue plasminogen activator (rtPA) and mechanical thrombectomy (MT) in patients treated with direct oral anticoagulants (DOACs) before stroke has not been fully investigated. Therefore, we aimed to investigate the safety of recanalization therapy in patients receiving DOACs.

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The influence of scene tilt on saccade directions is amplitude dependent

Stephanie M. Reeves a, Jorge Otero-Millan

doi : 10.1016/j.jns.2023.120635

Volume 448, 15 May 2023, 120635

When exploring a visual scene, humans make more saccades in the horizontal direction than any other direction. While many have shown that the horizontal saccade bias rotates in response to scene tilt, it is unclear whether this effect depends on saccade amplitude.

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Clinical spectrum and genotype-phenotype associations in Finnish patients with Wilson's disease

Jussi O.T. Sipil ̈a a,b,*, Laura Kyt ̈ovuori c,d, Valtteri Kaasinen a,e

doi : 10.1016/j.jns.2023.120620

Volume 448, 15 May 2023, 120620

Genotype-phenotype correlation data covering all ages of Wilson's disease onset in Caucasian patients are limited. We therefore analyzed genotype-phenotype correlations in a retrospective cohort of Finnish patients.

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An autopsy case of copper deficiency myelopathy and selenium deficiency-associated central nervous system disorder after total parenteral nutrition

Ryuichi Koizumia,b,*, Hideki Katoc, Akio Akagia, Yuichi Rikua, Jun Sonea, Hiroaki Miyaharaa, Takuya Oguric, Hiroyuki Yuasac, Fumiaki Tanakab, Mari Yoshidaa, Yasushi Iwasaki

doi : 10.1016/j.jns.2023.120636

Volume 448, 15 May 2023, 120636

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Restricted access in the emergency department prevents MRI from being the workhorse for ischemic stroke care

Mukesh Kumara,*, Sherry Hub, Steven Beyeac,d, Noreen Kamala,b,e a Department of Industrial Engineering, Dalhousie University, Halifax, Canada

doi : 10.1016/j.jns.2023.120637

Volume 448, 15 May 2023, 120637

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Computed tomography versus short sequence magnetic resonance imaging in acute ischaemic stroke

Ho Lun Wonga,*, Ashraf Nasima,b, Amit K.J. Mandala, Robert Daviesc, Constantinos G. Missouris

doi : 10.1016/j.jns.2023.120638

Volume 448, 15 May 2023, 120638

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Lamotrigine and risk of arrhythmias: A global pharmacovigilance analysis

Lisa Ortsa,b, Clara Flumiana,b, François Montastruc

doi : 10.1016/j.jns.2023.120644

Volume 448, 15 May 2023, 120644

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Multimodal evaluation of carpal tunnel syndrome in a pre-symptomatic TTR mutation carrier

A. Salvalaggioa,b, M. Cacciavillanic, C. Tiengod, A. Ciprianie, L. Frizzierof, M. Fedrigog, S. Rizzog, A. Angelinig, R. Gasparottih, C. Briania,

doi : 10.1016/j.jns.2023.120596

Volume 448, 15 May 2023, 120596

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Antiphospholipid syndrome mimicking posterior cortical atrophy and the “railroad track� sign on brain fluorodeoxyglucose-positron emission tomography

Arenn F. Carlosa, Jonathan Graff-Radforda, Brian A. Cruma, Mary M. Machuldab, Nha Trang Thu Phamc, Val J. Lowec, Jennifer L. Whitwellc, Keith A. Josephs

doi : 10.1016/j.jns.2023.120615

Volume 448, 15 May 2023, 120615

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