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Universal Precautions for People at Risk of Opioid Overdose in North America
Evan Wood, MD, PhD1; Eri D. Solomon2; Scott E. Hadland, MD, MPH, MS3,4
doi : 10.1001/jamainternmed.2023.0116
May 2023, Vol 183, No. 5, Pages 400-500
Evaluating the Role of System-Generated Communications in Health Care Organizations
Amy N. Duckro, DO, MPH1; John F. Steiner, MD, MPH2
Effect of Routine Invasive vs Conservative Strategy in Older Adults With Frailty and Non–ST-Segment Elevation Acute Myocardial Infarction
Juan Sanchis, PhD1; Héctor Bueno, PhD2; Gema Miñana, PhD1; Carme Guerrero, MD3; David MartÃ, MD4; Manuel MartÃnez-Sellés, PhD5; Laura DomÃnguez-Pérez, MD2; Pablo DÃez-Villanueva, MD6; Jose A. Barrabés, PhD7; Francisco MarÃn, PhD8; Adolfo Villa, MD9; Marcelo SanmartÃn, MD10; Cinta Llibre, MD11; Alessandro SionÃs, PhD12; Antoni Carol, MD13; Sergio GarcÃa-Blas, PhD1; Elena Calvo, MD3; MarÃa José Morales Gallardo, MD4; Jaime ElÃzaga, PhD5; Iván Gómez-Blázquez, MD2; Fernando Alfonso, PhD6; Bruno GarcÃa del Blanco, MD7; Julio Núñez, PhD1; Francesc Formiga, PhD3; Albert Ariza-Solé, PhD3
doi : 10.1001/jamainternmed.2023.0047
Importance To our knowledge, no randomized clinical trial has compared the invasive and conservative strategies in frail, older patients with non–ST-segment elevation acute myocardial infarction (NSTEMI).
Assessment of Patient Education Delivered at Time of Hospital Discharge
Shreya P. Trivedi, MD1,2; Sara Corderman, MD3; Elyse Berlinberg, BS4; Antoinette Schoenthaler, EdD5; Leora I. Horwitz, MD, MHS6
doi : 10.1001/jamainternmed.2023.0070
Importance Patient education at time of hospital discharge is critical for smooth transitions of care; however, empirical data regarding discharge communication are limited.
Association of Life Expectancy With Surveillance Colonoscopy Findings and Follow-up Recommendations in Older Adults
Audrey H. Calderwood, MD, MS1,2; Tor D. Tosteson, ScD2,3,4; Qianfei Wang, MS2; Tracy Onega, PhD, MPAS5; Louise C. Walter, MD6,7
doi : 10.1001/jamainternmed.2023.0078
Importance Surveillance after prior colon polyps is the most frequent indication for colonoscopy in older adults. However, to our knowledge, the current use of surveillance colonoscopy, clinical outcomes, and follow-up recommendations in association with life expectancy, factoring in both age and comorbidities, have not been studied.
Clinical Trials Portfolio and Regulatory History of Idelalisib in Indolent Non-Hodgkin Lymphoma
Titas Banerjee, MD1; Myung Sun Kim, MD1; Alyson Haslam, PhD2; Vinay Prasad, MD2
doi : 10.1001/jamainternmed.2023.0190
Importance Idelalisib is a first-in-class phosphatidylinositol 3-kinase inhibitor that received US Food and Drug Administration accelerated approval in July 2014 as a single-agent treatment for relapsed follicular lymphoma (FL) and small lymphocytic lymphoma (SLL). Serious adverse effects were reported in 2016 leading to termination of postmarketing registry trials. However, idelalisib remained on the market until 2022 when Gilead voluntarily withdrew the drug for the accelerated approval indication.
Six-Year Cognitive Trajectory in Older Adults Following Major Surgery and Delirium
Zachary J. Kunicki, PhD, MS, MPH1; Long H. Ngo, PhD2; Edward R. Marcantonio, MD, SM3; Douglas Tommet, MS1; Yi Feng, MA4; Tamara G. Fong, MD, PhD5; Eva M. Schmitt, PhD6; Thomas G. Travison, PhD3; Richard N. Jones, ScD1; Sharon K. Inouye, MD, MPH3
doi : 10.1001/jamainternmed.2023.0144
Importance The study results suggest that delirium is the most common postoperative complication in older adults and is associated with poor outcomes, including long-term cognitive decline and incident dementia.
Comparative Effectiveness of Fludrocortisone and Hydrocortisone vs Hydrocortisone Alone Among Patients With Septic Shock
Nicholas A. Bosch, MD, MSc1; Bijan Teja, MD2,3; Anica C. Law, MD, MS1; Brandon Pang, MD1; S. Reza Jafarzadeh, DVM, MPVM, PhD4; Allan J. Walkey, MD, MSc1
doi : 10.1001/jamainternmed.2023.0258
Importance Patients with septic shock may benefit from the initiation of corticosteroids. However, the comparative effectiveness of the 2 most studied corticosteroid regimens (hydrocortisone with fludrocortisone vs hydrocortisone alone) is unclear.
Value Placed on Comfort vs Life Prolongation Among Patients Treated With Maintenance Dialysis
Susan P. Y. Wong, MD, MS1; David K. Prince, PhD1; Manjula Kurella Tamura, MD, MPH2; Yoshio N. Hall, MD, MS1; Catherine R. Butler, MD, MA1; Ruth A. Engelberg, PhD1; Elizabeth K. Vig, MD, MPH1; J. Randall Curtis, MD, MPH2,3; Ann M. O’Hare, MD, MA1
doi : 10.1001/jamainternmed.2023.0265
Importance Patients receiving maintenance dialysis experience intensive patterns of end-of-life care that might not be consistent with their values.
Association of Preoperative Medical Consultation With Reduction in Adverse Postoperative Outcomes and Use of Processes of Care Among Residents of Ontario, Canada
Weiwei Beckerleg, MD, MPH1,2; Daniel Kobewka, MD, MSc1,3,4; Duminda N. Wijeysundera, MD, PhD5,6,7; Manish M. Sood, MD, MSc2,3,4,8; Daniel I. McIsaac, MD, MPH2,3,4,9
doi : 10.1001/jamainternmed.2023.0325
Importance It is uncertain whether preoperative medical consultation reduces adverse postoperative clinical outcomes.
JAMA Internal Medicine—The Year in Review, 2022
Rita F. Redberg, MD, MSc1,2
Importance of Designing Trials for Older Adults With Complex Medical Conditions
Andrew J. Foy, MD1; David L. Brown, MD2
Bridging the Know-Do Gap in Hospital Care Transitions
Charlie M. Wray, DO, MS1,2; Christine D. Jones, MD, MS3,4
Should We Add Fludrocortisone to Hydrocortisone for Treatment of Septic Shock?
Michael A. Matthay, MD1; Issa J. Dahabreh, MD, ScD2; B. Taylor Thompson, MD3
Preoperative Medical Consultation—Time to Reevaluate a Questionable Process
Mutya Mithi Del Rosario, MD1,2; Rita F. Redberg, MD, MSc3,4; Deborah Grady, MD, MPH3,5
Mortality Trends Among Adults Experiencing Homelessness in Boston, Massachusetts From 2003 to 2018
Kirsten A. Dickins, PhD, AM, APRN, FNP-C1,2,3; Danielle R. Fine, MD, MSc3,4; Logan D. Adams, MD4; Nora K. Horick, MS5; Elizabeth Lewis, MBA6,7; Sara E. Looby, PhD, APN-BC2,3,8; Travis P. Baggett, MD, MPH3,4,6
Association Between Pharmaceutical Industry Marketing Payments to Physicians and Intra-articular Hyaluronic Acid Administration to Medicare Beneficiaries
Nishant Uppal, MD, MBA1,2; Timothy S. Anderson, MD, MAS2,3,4
Return to Driving After Critical Illness
Kelly M. Potter, PhD, RN, CNE1; Valerie Danesh, PhD, RN2; Brad W. Butcher, MD3; Tammy L. Eaton, PhD, MSc, RN, FNP-BC4; Anthony D. McDonald, PhD5; Timothy D. Girard, MD, MSCI1
Computer-Estimated Heart Rate vs True Heart Rate—Be Aware of the Software
Laszlo Littmann, MD, PhD1
Giant T-wave Inversion in an Older Patient With Sudden Loss of Consciousness
Anping Cai, MD1; Zhiming Chen, MD2; Fengguang Kang, MD3
Incorrect ECG Diagnoses?—Follow the Leads
Xingli Xin, MD1; Xuanxuan Li, MD2; Qingjie Xin, MD3
Brugada Pattern, Tall Peaked T Waves, Absence of P Waves, and Broad QRS Complexes
Ziming Zhuang, MD1; Yangyi Lin, MD2
What Should I Know About Stopping Routine Cancer Screening?
Grace Y. Zhang, MD1,2; Michael A. Incze, MD, MSEd3,4
Recall of Philips Respironics Ventilators and CPAP Machines—Breakdowns in Medical Device Surveillance
Robert A. Lowe, MD, MPH1
Perioperative Risk Assessment and Avoiding Overuse of Anesthesia Care for Routine Cataract Surgery
Adam A. Dalia, MD, MBA1; Timothy Houle, PhD1; Jeanine Wiener-Kronish, MD1
Perioperative Risk Assessment and Avoiding Overuse of Anesthesia Care for Routine Cataract Surgery
Achia Nemet, MD1; Raimo Tuuminen, MD, PhD2,3
Perioperative Risk Assessment and Avoiding Overuse of Anesthesia Care for Routine Cataract Surgery—Reply
Dhivya Perumal, MD1; Sei J. Lee, MD, MAS2,3; Catherine L. Chen, MD, MPH1,4
Improving Clinical Applicability of Mortality Prediction Models Among Persons With Dementia
Sanne S. Mooldijk, BSc1; Silvan Licher, MD, PhD1; Frank J. Wolters, MD, PhD1
Improving Clinical Applicability of Mortality Prediction Models Among Persons With Dementia—Reply
William James Deardorff, MD1,2; Alexander K. Smith, MD, MS, MPH1,2; Sei J. Lee, MD, MAS1,2
