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Preoperative Cognitive Impairment and Cardiac Surgery.
Nathan, Naveen MD
doi : 10.1213/ANE.0000000000006518
Volume 136(6) pgs. 1015-1227,e25-e47 June 2023
Postoperative Outcomes in Elderly Patients Undergoing Cardiac Surgery With Preoperative Cognitive Impairment: A Systematic Review and Meta-Analysis.
Au, Emily BSc *; Thangathurai, Gowtham BHSc +; Saripella, Aparna MSc *; Yan, Ellene HBSc *,++; Englesakis, Marina MLIS [S]; Nagappa, Mahesh MBBS [//]; Chung, Frances MBBS, MD, FRCPC *
doi : 10.1213/ANE.0000000000006346
Older patients with preoperative cognitive impairment are at risk for increased postoperative complications after noncardiac surgery.
Surgical Outcomes in High and Low Income Countries.
Nathan, Naveen MD
Failure to Rescue and Mortality Differences After Appendectomy in a Low-Middle-Income Country and the United States.
Rosero, Eric B. MD, MSc *; Eslava-Schmalbach, Javier MD, MSc, PhD +; Garzon-Orjuela, Nathaly MD, MSc +; Buitrago, Giancarlo MD, PhD ++; Joshi, Girish P. MBBS, MD, FFARCS *
doi : 10.1213/ANE.0000000000006336
Major disparities in complications and mortality after appendectomy between countries with different income levels have not been well characterized, as comparative studies at patient level between countries are scant.
Antithrombin Replacement in Cardiac Surgery: Was Too Much of a Good Thing Bad?.
Mazzeffi, Michael MD, MPH, MSc, FASA *; Tanaka, Kenichi MD +
The Rise and Fall of Antithrombin Supplementation in Cardiac Surgery.
Ranucci, Marco MD, FESC; Baryshnikova, Ekaterina PhD (Biol); Pistuddi, Valeria; Di Dedda, Umberto MD
doi : 10.1213/ANE.0000000000006314
AB Various cohort studies, both retrospective and prospective, showed that low antithrombin levels after cardiac surgery (at the arrival in the intensive care unit and during the next days) were associated with a number of adverse outcomes, including surgical reexploration and thromboembolic events, eventually leading to prolonged stay in the intensive care.
Is Industry- Versus Government-Sponsored Research a Zero-Sum Game?.
Kain, Zeev N. MD, MBA *,+,++; Tsai, Mitchel MD, MMM [S]; Browne, James MD [//]
Pro-Con Debate: Interdisciplinary Perspectives on Industry-Sponsored Research.
Sessler, Daniel I. MD *; Alman, Benjamin MD +; Treggiari, Miriam M. MD, PhD, MPH ++; Mont, Michael A. MD [S]
doi : 10.1213/ANE.0000000000006386
Nearly all new devices and drugs come from industry that provides two-thirds of the funding for medical research, and a much higher fraction of clinical research. Realistically, without corporate-funded studies, perioperative research would stagnate with little innovation and few new products.
Beta Agonists for Prevention of Respiratory Adverse Events in Children Undergoing Adenotonsillectomy: Long-Acting, Short Acting, or Not Acting.
Adler, Adam C. MS, MD, FAAP, FASE *,+; von Ungern-Sternberg, Britta S. MD, PhD, DEAA, FANZCA ++,[S],||
Effect of Tulobuterol Patch Versus Placebo on the Occurrence of Respiratory Adverse Events in Children Undergoing Tonsillectomies: A Randomized Controlled Trial.
Kim, Eun-Hee MD, PhD *; Lee, Sang Hyun MD, PhD +; Kim, Jin Kyoung PhD +; Park, Yong-Hee MD, PhD ++; Kang, Pyoyoon MD *; Park, Jung-Bin MD *; Ji, Sang-Hwan MD, PhD *; Jang, Young-Eun MD *; Lee, Ji-Hyun MD, PhD *; Kim, Jin-Tae MD, PhD *; Kim, Hee-Soo MD, PhD *
doi : 10.1213/ANE.0000000000006355
Perioperative respiratory adverse events are common in children. We aimed to evaluate the effect of the transdermal [beta]-2 agonist, tulobuterol, compared with that of placebo on the incidence of perioperative respiratory adverse events in pediatric patients undergoing tonsillectomy.
Effect of Different Administration Routes of Dexmedetomidine on Postoperative Delirium in Elderly Patients Undergoing Elective Spinal Surgery: A Prospective Randomized Double-Blinded Controlled Trial.
Niu, Jing-Yi MD *; Yang, Na MD *; Tao, Qing-Yu MD *; He, Yan MD +; Hou, Yong-Bo MD +; Ning, Ren-De MD ++; Yu, Jun-Ma MD *
doi : 10.1213/ANE.0000000000006464
Intravenous dexmedetomidine has been reported to decrease the occurrence of postoperative delirium (POD) in elderly patients. Nevertheless, some previous studies have indicated that intratracheal dexmedetomidine and intranasal dexmedetomidine are also effective and convenient.
Clinical Performance of Decision Support Systems in Anesthesia, Intensive Care, and Emergency Medicine: A Systematic Review and Meta-Analysis.
Harutyunyan, Robert MSc *; Jeffries, Sean D. MSc *; Ramirez-GarciaLuna, Jose L. MD, MSc, PhD *; Hemmerling, Thomas M. MD, MSc, DEAA *,+
doi : 10.1213/ANE.0000000000006500
Medical technology is expanding at an alarming rate, with its integration into health care often reflected by the constant evolution of best practices.
Limited English Proficiency and Perioperative Patient-Centered Outcomes: A Systematic Review.
Luan-Erfe, Betty M. MD; Erfe, J. Mark MD, MPH; DeCaria, Bruno MD; Okocha, Obianuju MD
doi : 10.1213/ANE.0000000000006159
AB This systematic review assesses whether limited-English proficiency (LEP) increases risk of having poor perioperative care and outcomes. This review was conducted according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines.
Current Evidence and Rationale to Guide Perioperative Management, Including Transfusion Decisions, in Patients With Sickle Cell Disease.
Azbell, Roberta C. G. MD *; Lanzkron, Sophie M. MD, MHS +; Desai, Payal C. MD ++
doi : 10.1213/ANE.0000000000006463
AB Sickle cell disease (SCD) is a collection of inherited hemoglobin disorders that results in chronic hemolytic anemia, vaso-occlusion, pain, and end organ damage.
Restricted Polypharmacy Compared to Usual Care in Mechanically Ventilated Patients: A Retrospective Cohort Study.
Bose, Somnath MD, MPH, FASA *; Lehman, Li-Wei PhD +,++; Talmor, Daniel MD, MPH *; Shahn, Zachary PhD +,[S]
doi : 10.1213/ANE.0000000000006419
Adverse effects of excessive sedation in critically ill mechanically ventilated patients are well described. Although guidelines strongly recommend minimizing sedative use, additional agents are added as infusions, often empirically.
Outpatient Treatment With Gabapentin in Women With Severe Acute Pain After Cesarean Delivery Is Ineffective: A Randomized, Double-Blind, Placebo-Controlled Trial.
Fowler, Cedar MD, PhD; Chu, Amy W. MD; Guo, Nan PhD; Ansari, Jessica R. MD; Shafer, Steven L. MD; Flood, Pamela D. MD
doi : 10.1213/ANE.0000000000006429
Most of the 1.1 million women who deliver by cesarean in the United States each year have an uncomplicated recovery. However, severe pain resistant to standard multimodal therapy within the first days after surgery is associated with an increased risk for prolonged pain and opioid use.
Tracheostomy, Feeding-Tube, and In-Hospital Postoperative Mortality in Children: A Retrospective Cohort Study.
Brown, Sydney E. S. MD, PhD *; Hall, Matt PhD +; Cassidy, Ruth B. MS *; Zhao, Xinyi PhD *; Kheterpal, Sachin MD, MBA *; Feudtner, Chris MD, PhD, MPH ++
doi : 10.1213/ANE.0000000000006413
Neuromuscular/neurologic disease confers increased risk of perioperative mortality in children. Some patients require tracheostomy and/or feeding tubes to ameliorate upper airway obstruction or respiratory failure and reduce aspiration risk.
Evaluation of a Protocol for the Management of Maintenance and Reversal of Rocuronium Block Using Neostigmine or Sugammadex.
Thilen, Stephan R. MD, MS *; Liang, Tinny MD, MS +; Kruse, Timothy N. MD *; Cain, Kevin C. PhD ++; Treggiari, Miriam M. MD, MPH, PhD [S]; Bhananker, Sanjay M. MBBS, MD, FRCA *
doi : 10.1213/ANE.0000000000006510
Postoperative residual neuromuscular blockade (PRNB) is defined as an adductor pollicis train-of-four ratio (TOFR) <0.9. It is a common postoperative complication when nondepolarizing muscle relaxants are either not reversed or reversed with neostigmine.
Anesthetic Management and Deep Sedation After Emergence From General Anesthesia: A Retrospective Cohort Study.
Deljou, Atousa MD *; Soleimani, Jalal MD +; Martin, David P. MD, PhD *; Schroeder, Darrell R. MS ++; Sprung, Juraj MD, PhD *; Weingarten, Toby N. MD *
doi : 10.1213/ANE.0000000000006470
Residual deep sedation during anesthesia recovery may predict postoperative complications. We examined the incidence and risk factors for deep sedation after general anesthesia.
Transnasal Videoendoscopy for Preoperative Airway Risk Stratification: Development and Validation of a Multivariable Risk Prediction Model.
Barclay-Steuart, Alexander MD, MBA *; Gro[latin sharp s]hennig, Hanna L. *; Sasu, Phillip MD *; Wunsch, Viktor A. MD *; Stadlhofer, Rupert MD +; Berger, Joanna MD +; Stark, Maria MSc ++; Sehner, Susanne MSc ++; Zollner, Christian MD *; Petzoldt, Martin MD *
doi : 10.1213/ANE.0000000000006418
Transnasal flexible videoendoscopy (TVE) of the larynx is a standard of care for the detection and staging of pharyngolaryngeal lesions in otorhinolaryngology. Patients frequently present with existing TVE examinations before anesthesia.
Examining Subjective Psychological Experiences of Postoperative Delirium in Older Cardiac Surgery Patients.
Cohen, Caitlin L. BPsych (Hons) *,+; Atkins, Kelly J. BPsych (Hons), DPsych, Clin, Neuro *,+,++; Evered, Lisbeth A. Bsc, MBiostat, PhD +,++,[S]; Silbert, Brendan S. MB, BS +,++; Scott, David A. MB, BS, PhD +,++
doi : 10.1213/ANE.0000000000006226
Postoperative delirium (POD) is an acute syndrome including inattention and impaired cognition that affects approximately 42% of older cardiac surgical patients.
Neuraxial Use Among Total Knee and Hip Arthroplasty Patients With Multiple Sclerosis or Myasthenia Gravis.
Illescas, Alex MPH *; Zhong, Haoyan MPA *; Liu, Jiabin MD, PhD *,+; Cozowicz, Crispiana MD ++; Poeran, Jashvant MD, PhD [S]; Memtsoudis, Stavros G. MD, PhD, MBA, FCCP *,+,||
doi : 10.1213/ANE.0000000000006471
Surgical patients with preexisting neurological diseases create greater challenges to perioperative management, and choice of anesthetic is often complicated.
Racial/Ethnic Variability in Use of General Anesthesia for Pediatric Magnetic Resonance Imaging.
Gan, Ziyu BS *; Rosenbloom, Julia M. MD +; De Souza, Elizabeth PhD ++; Anderson, T. Anthony MD, PhD ++
doi : 10.1213/ANE.0000000000006403
Children increasingly undergo diagnostic imaging procedures, sometimes with general anesthesia (GA). It is unknown whether the use of GA differs by race/ethnicity among children undergoing magnetic resonance imaging (MRI) scans.
Direct Comparison of Peak Bulk Flow Rate of Programmable Intermittent Epidural Bolus and Manual Epidural Bolus Using a Closed-End Multiorifice Catheter: An Experimental Study.
Younger, Joshua D. MD *; Faryami, Ahmad BS +; Prasad, Monica MD ++; Viar, Daniel [S]; Menkara, Adam +; Tang, Amy PhD [//]; Harris, Carolyn A. PhD [P]
doi : 10.1213/ANE.0000000000006268
The programmable intermittent epidural bolus (PIEB) has been popularized as the optimal delivery technique for labor analgesia. Suggested advantages of this method are less local anesthetic consumption, improved maternal satisfaction, potentially shorter duration of labor, and decreased workload requirements for the anesthesia providers.
Alfaxalone Alleviates Neurotoxicity and Cognitive Impairment Induced by Isoflurane Anesthesia in Offspring Rats.
Zhao, Xingkai MS; Li, Zhendong MS; Guo, Yizhe MS; Liu, Qi BAgr; Qing, Mengshi BAgr; Sheng, Yuhan BAgr; Chen, Ying BAgr; Xie, Luolan MS; Zhou, Zhenlei PhD
doi : 10.1213/ANE.0000000000006420
The anesthetic isoflurane can cause neurotoxicity in fetuses and offspring of rats, affecting their neurodevelopment. However, the underlying mechanisms and therapeutic targets of isoflurane-induced neurotoxicity remain to be identified.
Sugammadex Use for Reversal in Nonobstetric Surgery During Pregnancy: A Reexamination of the Evidence.
Gaston, Ian N. MD *; Lange, Elizabeth M. S. MD +; Farrer, Jason R. MD *; Toledo, Paloma MD, MPH *,++
Reclaiming the Etiquette of Extubation.
Wakabayashi, Koji MBChB; le Roux, Johannes J. MBChB; Jooma, Zainub FCA, Cert Crit Care, MBChB
The Gold Standard of Pediatric Hemodynamic Monitoring: Not All That Glitters Is Gold.
Ricci, Zaccaria MD; Iacobelli, Roberta MD; Romagnoli, Stefano MD
In Response.
Greiwe, Gillis MD; Saugel, Bernd MD; Schulte-Uentrop, Leonie MD
Recording Clinical Interactions and Wiretapping Laws.
Brook, Karolina MD; de Meneses, Flavio G. A. MD; Quraishi, Sadeq A. MD, MHA, MMSc
In Response.
Quinonez, Zoel A. MD; Pyke-Grimm, Kimberly A. PhD, RN, CNS, CPHON; Char, Danton MD, MAS
Which Airway Pressure Determines Air Leakage While Using a Laryngeal Mask Airway Device?.
Sadik, Mohammed MD, IDRA; Biyani, Ghansham MD, DNB, EDAIC; Metta, Rajasekhar MD; Dang, Deepanshu MD
Is the Latency Between Symptom Onset and Diagnosis a Confounder in Understanding the Potential Relationship Between Intraoperative Blood Pressure and Long-Term Neurodevelopmental and Neuropsychiatric Disorders in Children?.
Lemanowicz, Alexandra N. BSc; Grocott, Hilary P. MD, FRCPC
In Response.
Ing, Caleb MD, MS; DeStephano, David MPH; Yang, Zhixin MS; Reighard, Charles MD; Lackraj, Deven MPH; Geneslaw, Andrew MD, MS; Miles, Caleb PhD; Kim, Minjae MD, MS
Definition and Treatment of Hyperfibrinolysis During Liver Transplantation: Are All Viscoelastic Tests Created Equal?.
Abuelkasem, Ezeldeen MBBCh, MSc, FASE; Mazzeffi, Michael A. MD, MPH, FASA; Tanaka, Kenichi A. MD, MSc
On the Importance of Transparency About the Internal Operation of Medical Devices.
Ozcan, Mehmet S. MD; Charchaflieh, Jean G. MD, DrPH
Postoperative Delirium Severity and Recovery Correlate With Electroencephalogram Spectral Features: Where Do We Start From?.
Nino, Maria C. MD; Guerra, Jose D. MD
In Response.
Palanca, Ben Julian A. MD, PhD, MSCI; Kafashan, MohammadMehdi PhD; Guay, Christian S. MD
Role of Intrinsic Pathway in Coagulation After Use of Activated Prothrombin Complex Concentrate in Neonatal Cardiac Surgery.
Kahntroff, Stephanie MDe; Hollander, Kimberly MD; Stewart, Kenneth PhD; Tanaka, Kenichi A. MD, MSc
In Response.
Navaratnam, Manchula MBChB, FRCA; Boothroyd, Derek PhD; Zhang, Shiqi MS; Williams, Glyn D. MBChB, FFA
Night Float Rotations: Continued Questions With Few Answers.
Windrix, Casey MD; Vandyck, Kofi MD; Tanaka, Kenichi A. MD, MSc; Butt, Amir L. MD, MPH
Ice Slush Oculocardiac Reflex Reduction.
Cobb, Lindsey B. MD; Arnold, Robert W. MD
Safety Profile of Diprospan for Local Infiltration in Diabetic Patients.
Rudingwa, Priya MD; Ramadurai, Rajasekar MD; Arulprakasam, Santhosh MD; Ravichandrane, Banupriya MD
In Response.
Han, Xueye MD; Ren, Tong MD; Wang, Yang MD; Ji, Nan MD; Luo, Fang MD
Additional Barrier to Protect Health Care Workers During Intubation: Erratum.
