British Journal of Dermatology




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Editor's Choice – John Ingram – July 2023

doi : 10.1093/bjd/ljad176

British Journal of Dermatology, Volume 189, Issue 1, July 2023, Pages i–ii,

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Three years on, COVID-19 and the skin: long-term impacts, emerging trends and clinical practice

Esther E Freeman, Ignacio Garcia-Doval, Luigi Naldi, Roderick J Hay

doi : 10.1093/bjd/ljad131

British Journal of Dermatology, Volume 189, Issue 1, July 2023, Pages 1–3

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Malignancy risk in atopic dermatitis: heterogenous effects and perspectives

Ida Vittrup

doi : 10.1093/bjd/ljad119

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Epidermolysis bullosa: time to come together for better outcomes

Gabriela Petrof, Anna E Martinez

doi : 10.1093/bjd/ljad123

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Does the understanding of signalling pathways pave the way to therapies for keratinization disorders?

Hans C Hennies

doi : 10.1093/bjd/ljad139

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From genetic characterization to new potential therapeutic options: targeting Bcl-xL in Merkel carcinoma

Thibault Kervarrec

doi : 10.1093/bjd/ljad150

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Is the Scale of Alopecia Areata Distress a new method of assessing the psychological burden of alopecia areata?

Taisuke Ito, Reiko Kageyama

doi : 10.1093/bjd/ljad153

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Can brepocitinib be formulated into an effective topical therapy to treat mild-to-moderate chronic plaque psoriasis?

William C Cranwell, Rodney D Sinclair

doi : 10.1093/bjd/ljad157

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Further evidence for the long-term safety of guselkumab

Antonia Lloyd-Lavery

doi : 10.1093/bjd/ljad161

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Relative impact of traditional vs. newer oral antifungals for dermatophyte toenail onychomycosis: a network meta-analysis study

Aditya K Gupta, Maanasa Venkataraman, Mary A Bamimore

doi : 10.1093/bjd/ljad070

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Efficacy and safety of baricitinib in combination with topical corticosteroids in paediatric patients with moderate-to-severe atopic dermatitis with an inadequate response to topical corticosteroids: results from a phase III, randomized, double-blind, placebo-controlled study (BREEZE-AD PEDS)

Antonio Torrelo, Barbara Rewerska, Maria Galimberti, Amy Paller, Chin-Yi Yang, Apurva Prakash, Danting Zhu, Marco Antonio G Pontes Filho, Wen-Shuo Wu, Lawrence F Eichenfield

doi : 10.1093/bjd/ljad096

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Efficacy and safety of topical brepocitinib cream for mild-to-moderate chronic plaque psoriasis: a phase IIb randomized double-blind vehicle-controlled parallel-group study

Megan N Landis, Stacy R Smith, Gabriel Berstein, Gerald Fetterly, Pranab Ghosh, Gang Feng, Vivek Pradhan, Sudeepta Aggarwal, Christopher Banfield, Elena Peeva, Michael S Vincent, Jean S Beebe, Sanela Tarabar

doi : 10.1093/bjd/ljad098

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Safety of guselkumab treatment for up to 5 years in patients with moderate-to-severe psoriasis: pooled analyses across seven clinical trials with more than 8600 patient-years of exposure

Mark G Lebwohl, Joseph F Merola, Katelyn Rowland, Megan Miller, Ya-Wen Yang, Jenny Yu, Yin You, Daphne Chan, Diamant Thaçi, Richard G Langley

doi : 10.1093/bjd/ljad115

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Malignancy risk in patients with atopic dermatitis: a population-based cohort study

Joy Wan, Daniel B Shin, Maha N Syed, Katrina Abuabara, Adina R Lemeshow, Zelma C Chiesa Fuxench, Joel M Gelfand

doi : 10.1093/bjd/ljad072

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Uptake of tumour necrosis factor-alpha inhibitor biosimilars for psoriasis: a drug utilization study from the British Association of Dermatologists Biologic and Immunomodulators Register (BADBIR)

Duc Binh Phan, Anthony P Bewley, Catherine H Smith, Teena Mackenzie, Christopher E M Griffiths, Mark Lunt, Richard B Warren, Zenas Z N Yiu

doi : 10.1093/bjd/ljad107

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Beyond health-related quality of life: initial psychometric validation of a new scale for addressing the gap in assessing the full range of alopecia areata psychosocial burden

Kristina Gorbatenko-Roth, Sarah Wood, Mattea Johnson, Irmina Wallander, Jaime Nugent, Maria Hordinsky

doi : 10.1093/bjd/ljad054

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Heterogeneity of reported outcomes in epidermolysis bullosa clinical research: a scoping review as a first step towards outcome harmonization

Eva W H Korte, Tobias Welponer, Jan Kottner, Sjoukje van der Werf, Peter C van den Akker, Barbara Horváth, Dimitra Kiritsi, Martin Laimer, Anna M G Pasmooij, Verena Wally, Maria C Bolling

doi : 10.1093/bjd/ljad077

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Chronic activation of Toll-like receptor 2 induces an ichthyotic skin phenotype

Hephzi Tagoe, Sakinah Hassan, Emily Bliss, Gehad Youssef, Wendy Heywood, Kevin Mills, John I Harper, Ryan F L O’Shaughnessy

doi : 10.1093/bjd/ljad095

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B-cell lymphoma-extra large is a promising drug target in Merkel cell carcinoma

Kaiji Fan, Nalini Srinivas, Linda Kubat, Jan Gravemeyer, Antje Sucker, Dirk Schadendorf, Thilo Gambichler, Jürgen C Becker

doi : 10.1093/bjd/ljad099

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Circulating biomarkers are associated with disease severity of chronic hand eczema and atopic dermatitis

Anna S Quaade, Xing Wang, Julie B K Sølberg, Nina H Ulrich, Benjamin D McCauley, Jacob P Thyssen, Christine Becker, Jeanne D Johansen

doi : 10.1093/bjd/ljad110

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Psychosocial impact of pyoderma gangrenosum: a patient perspective

Dasia Crowder, Samantha Herbert, Reneé Haughton

doi : 10.1093/bjd/ljad074

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We are not ‘Other’ populations: building research, education and clinical capacity around gender variance in dermatology

Gagandeep Singh, Philip Doiron, Erin Dahlke

doi : 10.1093/bjd/ljad073

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Investigator Global Assessment for impetiginization in atopic dermatitis: development and initial reliability testing

Aviël Ragamin, Ron A Tupker, Marlies de Graaf, Thomas Rustemeyer, Suzanne G M A Pasmans, Renske Schappin, Marie L A Schuttelaar

doi : 10.1093/bjd/ljad085

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Gain-of-function variants in the KDF1 gene cause hidradenitis suppurativa associated with ectodermal dysplasia by stabilizing IκB kinase α

Alban Ziegler, Frédéric Ebstein, Hanan Shamseldin, Clément Prouteau, Elke Krüger, Yousef M Binamer, Dominique Bonneau, Fowzan S Alkuraya, Ludovic Martin Author Notes

doi : 10.1093/bjd/ljad075

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Safety of guselkumab in patients with psoriasis with a history of malignancy: 5-year results from the VOYAGE 1 and VOYAGE 2 trials

Andrew Blauvelt, Diamant Thaçi, Kim A Papp, Vincent Ho, Kamran Ghoreschi, Byung Soo Kim, Megan Miller, Yaung-Kaung Shen, Yin You, Daphne Chan, Jenny Yu, Ya-Wen Yang, Mark G Lebwohl, Alice B Gottlieb, Jeffrey Crowley, Peter Foley

doi : 10.1093/bjd/ljad081

خرید پکیج و مشاهده آنلاین مقاله


KLK11 ichthyosis: large truncal hyperkeratotic pigmented plaques underscore a distinct autosomal dominant disorder of cornification

Takuya Takeichi, Yasutoshi Ito, John Y W Lee, Chiaki Murase, Yusuke Okuno, Yoshinao Muro, John A McGrath, Masashi Akiyama

doi : 10.1093/bjd/ljad082

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Abrocitinib as a novel treatment for lichen sclerosus

Chengbei Bao, Qiuyun Xu, Zhixun Xiao, Haiqing Wang, Renwei Luo, Bo Cheng, Chao Ji, Ting Gong

doi : 10.1093/bjd/ljad129

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The Generalized Pustular Psoriasis Physician Global Assessment (GPPGA) score: online assessment and validation study of a specific measure of GPP disease activity

A David Burden, Hervé Bachelez, Siew Eng Choon, Slaheddine Marrakchi, Tsen-Fang Tsai, Hamida Turki, Akimichi Morita, Mark G Lebwohl, Robert Bissonnette, Min Zheng, Milan J Anadkat, Alexander A Navarini, Ming Tang, Christian Thoma, Kristina Callis Duffin

doi : 10.1093/bjd/ljad071

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Acute hepatic failure in trimethoprim-induced drug rash with eosinophilia and systemic symptoms (DRESS)

Aveen Connolly, Sarah Walsh, Marianna Philippidou, Jon Salisbury, Daniel Creamer

doi : 10.1093/bjd/ljad087

خرید پکیج و مشاهده آنلاین مقاله


The geographical variation of melanoma, basal and squamous cell carcinoma in England

Anna Ascott, Birgitta van Bodegraven, Sally Vernon, Cate H Orteu, Zoe C Venables

doi : 10.1093/bjd/ljad100

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Head lice: evidence that resistance to physically acting treatments is developing

Ian F Burgess, Elizabeth R Brunton

doi : 10.1093/bjd/ljad106

خرید پکیج و مشاهده آنلاین مقاله


Photoprotection and skin cancer education: the experiences of renal transplant recipients, a qualitative study – why the ‘personal touch’ is important

Laoise Griffin, Pauline O’Reilly, Marcus Murphy, Gemma Prendergast, Emily Pender, Olga Tummon, Matthew Griffin, Mary Laing

doi : 10.1093/bjd/ljad116

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Cutaneous features at injection sites of intravenous mephedrone

Manuel Agud de Dios, Jorge Arroyo-Andres, Carmen Rubio-Muniz, Maria Concepcion Garrido, Eloy Tarin-Vicente

doi : 10.1093/bjd/ljad064

خرید پکیج و مشاهده آنلاین مقاله


A multistep approach from scoping review to strong evidence: biomarkers in psoriasis

E Sbidian

doi : 10.1093/bjd/ljac101

خرید پکیج و مشاهده آنلاین مقاله


Which patients with melanoma are a priority for monitoring to detect new primary melanoma?

Aimilios Lallas

doi : 10.1093/bjd/ljad125

خرید پکیج و مشاهده آنلاین مقاله


OralsO01 Loss of TGFBR2 and activation of PI3 kinase signalling is associated with metastatic cutaneous squamous cell carcinomas

Mairi Treanor-Taylor, Ying Zhang, Daniel Schreyer, Catherine Harwood, Irene Leigh, Peter Bailey, David Wotton, Gareth Inman

doi : 10.1093/bjd/ljad174.001

خرید پکیج و مشاهده آنلاین مقاله


O02 Neoantigens from actinic keratosis are predicted to be more immunogenic than those from cutaneous squamous cell carcinoma – a strategy for immune escape?

Jason Thomson, Catherine Harwoood, Jessica Strid, Eugene Healy, Jun Wang

doi : 10.1093/bjd/ljad174.002

خرید پکیج و مشاهده آنلاین مقاله


O03 HPV8 leads to Lrig1+ keratinocyte stem cell expansion into the overlying epidermis

Huw J Morgan, Boris Shorning, Carlotta Olivero, Cinzia Borgogna, Baki Akgul, Marisa Gariglio, Girish K Patel

doi : 10.1093/bjd/ljad174.003

خرید پکیج و مشاهده آنلاین مقاله


O04 HPV8 E6 leads to Lrig1+ keratinocyte stem cell expansion

Boris Shorning, Huw J Morgan, Carlotta Olivero, Cinzia Borgogna, Marisa Gariglio, Baki Akgul, Girish K Patel

doi : 10.1093/bjd/ljad174.004

خرید پکیج و مشاهده آنلاین مقاله


O05 Functional roles of lncRNA in cutaneous squamous cell carcinoma disease progression

Max Bone, Catherine Harwood, Irene Leigh, Peter Bailey, Gareth Inman

doi : 10.1093/bjd/ljad174.005

خرید پکیج و مشاهده آنلاین مقاله


O06 Exploring host–microbiome–immune interactions using singular and multispecies inoculations in optimized 3D skin models

Esmé McPolin-Hall, Abish Stephen, Claire Pardieu, Robert Allaker, Michae Philpott, Ranjit Bhogal, Jenny Pople, Rosalind Hannen

doi : 10.1093/bjd/ljad174.006

خرید پکیج و مشاهده آنلاین مقاله


O07 Filaggrin insufficiency renders keratinocyte-derived small extracellular vesicles capable of affecting CD1a-mediated T-cell responses and promoting allergic inflammation

Adrian Kobiela, Weronika Hewelt-Belka, Joanna E Frąckowiak, Natalia Kordulewska, Lilit Hovhannisyan, Aleksandra Bogucka, Rachel Etherington, Artur Piróg, Irena Dapic, Susanne Gabrielsson, Sara Brown, Graham S Ogg, Danuta Gutowska-Owsiak

doi : 10.1093/bjd/ljad174.007

خرید پکیج و مشاهده آنلاین مقاله


O08 Using single-cell transcriptomics to characterize early mechanisms of psoriasis resolution

Luc Francis, Daniel McCluskey, Clarisse Ganier, Xinyi Du-Harpur, David Baudry, Pawan Dhami, Jonathon Barker, Catherine Smith, Francesca Capon, Satveer Mahil

doi : 10.1093/bjd/ljad174.008

خرید پکیج و مشاهده آنلاین مقاله


O09 Dynamic impact of chronic inflammation on epidermal autophagy pathway

Nazia Uddin, Paola Ostano, Giovanna Chiorino, Jeremy di Domizio, Michel Gilliet, Mike Philpott, Rosalind Hannen, Daniele Bergamaschi

doi : 10.1093/bjd/ljad174.009

خرید پکیج و مشاهده آنلاین مقاله


O10 STAT3 activation in peripheral blood MAIT cells is a predictive biomarker of response to biologics targeting the IL-23/IL-17 axis

Shane Solanky, Salma Khan, Isabella Tosi, Hannah Dawe, Wan Xinyu, Rosa Andres Ejarque, Hira Bahadur Ale, Katarzyna Grys, Nick Dand, Satveer Mahil, Michael R Barnes, Christopher E M Griffiths, Nick J Reynolds, Catherine H Smith, Richard B Warren, Jonathan Barker, Paola Di Meglio on behalf of the PSORT Consortium

doi : 10.1093/bjd/ljad174.010

خرید پکیج و مشاهده آنلاین مقاله


O11 The human discs large protein (Dlg1) controls connexin 43 (Cx43) plasma membrane localization and gap junctional communication in keratinocytes

Harry Scott, Li Dong, Sharmila Srinivasan, Andrew Stevenson, Alasdair MacDonald, Paola Massimi, Lawrence Banks, Patricia Martin, Scott Johnstone, Sheila Graham

doi : 10.1093/bjd/ljad174.011

خرید پکیج و مشاهده آنلاین مقاله


O12 Environmental factors interact with FLG to affect cytokine expression in human primary keratinocytes

Luke Johnston, Mona Etorban, Hannes Becher, Martina Elias, Sara Brown

doi : 10.1093/bjd/ljad174.012

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O13 JAK inhibitors to restore skin barrier function in ARCI

Elena Giusto, Florence Enjalbert, Emanuel Rognoni, Matthew Caley, Edel O’Toole

doi : 10.1093/bjd/ljad174.013

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O14 Junctional epidermolysis bullosa: repairing the epidermal lipid barrier

Eleri Jones, Supatra Marsh, Ryan O'Shaughnessy, Monique Aumailley, John McGrath, Edel O’Toole, Matthew Caley

doi : 10.1093/bjd/ljad174.014

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O15 Using CRISPR-Cas9 to annotate the TYK2 pathway in psoriasis

Sarah Elyoussfi, Shraddha S Rane, Stephen Eyre, Richard B Warren

doi : 10.1093/bjd/ljad174.015

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O16 The novel roles of laminin α3 in epidermal barrier function and metabolism

Piotr Parzymies, Eleri Mai Jones, Andrew Mayes, David Messenger, Edel O’Toole, Matthew Caley

doi : 10.1093/bjd/ljad174.016

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O17 Endogenous double-stranded RNA (dsRNA) in melanoma: an attack from within

Shaymaa Sadeq, Ruth Plummer, Suwalak Chitcharoen, Penny Lovat, Glyn Nelson, Andreas Werner

doi : 10.1093/bjd/ljad174.017

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O18 Molecular crosstalk between PLCγ1 and STAT3 in cutaneous T-cell lymphoma

Victoria Campbell, Charlotte Flanagan, Isabella Tosi, Christine Jones, Sean Whittaker, Susan John, Tracey Mitchell

doi : 10.1093/bjd/ljad174.018

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O19 CYLD cutaneous syndrome tumours demonstrate increased NF-κB signalling and diminished collagen organisation.

Joseph Inns, Neil Rajan

doi : 10.1093/bjd/ljad174.019

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O20 Advanced melanoma is associated with distinct circulating B-cell profiles enriched with immunoregulatory and autoreactive features

Zena Willsmore, Silvia Crescioli, Lucy Booth, Roman Laddach, Rozalyn Yorke, Robert Harris, Jitesh Chauhan, Alicia Chenoweth, Rebecca Adams, Gabriel Osborn, Ashley Di Meo, Ioannis Prassas, Jenny L C Geh, Akshay J Patel, Gary W Middleton, Alastair D MacKenzie Ross, Ciaran Healey, Eleftherios P Diamandis, Khushboo Sinha, Yin Wu, Sean J Whittaker, Esperanza Perucha, Sophie Papa, Katie E Lacy, Sophia N Karagiannis

doi : 10.1093/bjd/ljad174.020

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O21 Single-cell RNA sequencing and proteomic analysis of dermal fibroblasts cultured from female scalp identifies significant alterations in cell populations with age

Richard Baker, Rachael Williams, Gillian Westgate, Alison Pawlus, Jeanna Zguris, Julie Thornton

doi : 10.1093/bjd/ljad174.021

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O22 Programmed cell death-1 receptor is a checkpoint in Tbet+ Th17 cells within the tumour microenvironment

Katie Smith, Jing Xuan Lim, Arian Laurence, Shoba Amarnath

doi : 10.1093/bjd/ljad174.022

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PostersP01 Tissue slice culture as a patient-derived explant model to investigate immunity and immunotherapy in cutaneous squamous cell carcinoma

George Coltart, Chester Lai, Aymen Al-Shamkhani, Eugene Healy

doi : 10.1093/bjd/ljad174.023

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P02 Potential for the loss of endothelial AMBRA1 expression in the tumour microenvironment to identify high-risk patient subsets with nonulcerated AJCC stage I/II melanoma

Roisin Stout, Katie Best, Ioana Cosgarea, Penny Lovat, Jane Armstrong

doi : 10.1093/bjd/ljad174.024

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P03 Hydroxypyridone antifungals induce myofibroblast apoptosis in an in vitro model of hypertrophic scars

Alice Lapthorn, Marcus Ilg, Justine Sullivan, Peter Dziewulski, Selim Cellek

doi : 10.1093/bjd/ljad174.025

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P04 Skin concentration of 7-dehydrocholesterol is not a limiting factor for vitamin D3 synthesis in older versus younger adults, and a similar response occurs to UVR in these age groups

Oktawia Borecka, John J Dutton, Jonathan C Y Tang, William D Fraser, Lesley E Rhodes

doi : 10.1093/bjd/ljad174.026

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P05 Inducible MDM2 ablation increases p53 expression to block papillomatogenesis in HK1.ras transgenic mice

Ana Gutierrez Crispini, Aleksandra Slosarska, David Greenhalgh

doi : 10.1093/bjd/ljad174.027

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P06 Functional MDM2 ablation in HK1.ras/fos-Δ5PTEN transgenic mice results in an elevated, p53-mediated block of carcinogenesis that depends upon p53 expression

Sofia Moula, Gavin Turnbull, David Greenhalgh

doi : 10.1093/bjd/ljad174.028

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P07 Optimizing DNA specificity and applicability of base and prime editors on COL7A1 variants causing recessive dystrophic epidermolysis bullosa

Imogen Brooks, Maria Rudnytska, Ruta Gebrezgabher, Lukasz Laczmanski, Gregory Newby, David Liu, John McGrath, Joanna Jackow

doi : 10.1093/bjd/ljad174.029

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P08 Dissection of the molecular and cellular heterogeneity of dermal fibroblasts in skin fibrosis

Abubkr Ahmed, Thomas Kirk, Laura Forster, Edel O’Toole, Himadri Gupta, Emanuel Rognoni

doi : 10.1093/bjd/ljad174.030

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P09 Short-term rho-associated kinase inhibitor treatment promotes primary keratinocyte growth without affecting keratinocyte stem cell properties

Vignesh Jayarajan, George T Hall, Theodoros Xenakis, Neil Bulstrode, Dale Moulding, Sergi Castellano, Wei-Li Di

doi : 10.1093/bjd/ljad174.031

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P10 Inducible 14-3-3 sigma/stratifin ablation cooperates with rasHa activation to accelerate papillomatogenesis and induce malignant conversion in transgenic mouse skin carcinogenesis

Rebecca Hardman-Carter, Revvekka Lefkati, Carol McMenemy, David Greenhalgh

doi : 10.1093/bjd/ljad174.032

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P12 Tetrapeptide matrikines synchronize circadian rhythms and promote proliferation in human skin cells

Zeyad El-Houni, Alexander Eckersley, Mike Bell, Eleanor Bradley, Victoria Newton, Michael Sherratt, Qing Jun Meng

doi : 10.1093/bjd/ljad174.033

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P13 Prediction and in vitro characterization of tetrapeptide matrikines with diverse effects on human dermal fibroblasts

Nathan Jariwala, Matiss Ozols, Alexander Eckersley, Rachel Watson, Bezaleel Mambwe, Andrew Gilmore, Laurent Debelle, Mike Bell, Eleanor Bradley, Yegor Doush, Richard Leroux, Olivier Peschard, Philippe Mondon, Caroline Ringenbach, Laure Bernard, Aurélien Pitois, Michael Sherratt

doi : 10.1093/bjd/ljad174.034

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P14 Whole-genome sequencing of malignant cylindroma in CYLD cutaneous syndrome reveals a clinically targetable somatic driver mutation

William Fostier, Ching Chiek Koh, Akhtar Husain, Shirin Namini, Serena Nik-Zainal, Neil Rajan

doi : 10.1093/bjd/ljad174.035

British Journal of Dermatology, Volume 189, Issue 1, July 2023, Page e19

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P15 Surface engineering of novel polydimethylsiloxane composites to attract bacteria: potential to treat chronic infected wounds and reduce antimicrobial resistance

Paul Norton, Maria Katsikogianni, David Ansell, Chien-Yi Chang, Julie Thornton

doi : 10.1093/bjd/ljad174.036

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P16 How does skin ageing-related basement membrane collagen loss affect the nucleus?

Simranpreet Kaur Summan, Andrew Mayes, David Gunn, Julien Gautrot, Matthew Caley, Edel O’Toole

doi : 10.1093/bjd/ljad174.037

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P17 A signature of IL-36 activation in systemic lupus erythematosus skin

Emma J Sumner, Daniel McCluskey, Satveer K Mahil, Myles Lewis, Francesca Capon

doi : 10.1093/bjd/ljad174.038

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P18 KLICK syndrome is a hyperproliferative inflammatory skin disorder

Hannah Cherry, Maddy Parsons, Joe Rastrick, Jonathan Hardman-Smart, Paola DiMeglio, John McGrath

doi : 10.1093/bjd/ljad174.039

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P19 Inducible 14-3-3 sigma/stratifin ablation accelerates malignant progression in HK1.ras/fos-Δ5PTENflx transgenic mouse skin carcinogenesis

Imogen Rawlinson, Carol McMenemy, David Greenhalgh

doi : 10.1093/bjd/ljad174.040

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P20 Engineered peptide for KLK5 inhibition – therapeutic intervention for atopic dermatitis

Jeffrey Mah, Derek Macmillan, Wei-Li Di

doi : 10.1093/bjd/ljad174.041

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P21 Tyrosine and serine STAT3 phosphorylation drives cutaneous squamous cell carcinoma in recessive dystrophic epidermolysis bullosa as demonstrated using a 3D in vitro model

Virginia Llopis-Hernandez, Katarzyna Balon, Dawei Chen, Jemima Mellerio, John McGrath, Joanna Jacków

doi : 10.1093/bjd/ljad174.042

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P22 Fibrosis in delayed wound healing in diabetes: the role of insulin-like growth factor binding proteins

Sharlene Were, Taryn Wilson, Patricia Martin, Catherine Wright

doi : 10.1093/bjd/ljad174.043

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P23 Inducible E-cadherin ablation drives malignant progression in HK1.ras.fos.PTENflx/flx carcinogenesis and induces conversion of HK1.fos.PTENflx/flx keratoacanthoma

Rema Zaweia, Abdullah Alyamani, Carol McMenemy, Jean Quinn, David Greenhalgh

doi : 10.1093/bjd/ljad174.044

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P24 Emollient use and effects on cutaneous allergen reactions: a preliminary study

Oludolapo Sherifat Katibi, Paul Andrew, Anna Poyner, Abigail Pinnock, Kirsty Brown, Rob Byers, Michael Cork, Simon Danby

doi : 10.1093/bjd/ljad174.045

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P25 Hsa-miR-6727-5p contributes to the impact of high-density lipoprotein on fibroblast wound healing in vitro

Khaled Bastaki, Jamie Tarlton, Richard Lightbody, Patricia Martin, Annette Graham

doi : 10.1093/bjd/ljad174.046

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P26 Characterization of skin barrier defects in atopic dermatitis patients using attenuated total reflection Fourier transform infrared spectroscopy

Samuel Williams, Simon Danby

doi : 10.1093/bjd/ljad174.047

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P27 Uncovering the roles of lysosomal protease cathepsin H in atopic dermatitis

Theresa Tachie-Menson, Atqiya Azizah, Aaron Hughes, Ryan O'Shaughnessy

doi : 10.1093/bjd/ljad174.048

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P28 Understanding ethnic inequality and barriers to participation in artificial intelligence (AI) image analysis research in dermatology

Alexandra Paolino, Wei Ren Tan, Shern-Ping Choy, Byung Jin Kim, Sarah Man Lin Lim, Jiwon Seo, Sze Ping Tan, Michael Duckworth, Bolaji Coker, Koyinsola Quadry, Gary Mulcahy, Jonathan N W N Barker, Magnus Lynch, Mark Stephen Corbett, Catherine H Smith, Satveer K Mahil

doi : 10.1093/bjd/ljad174.049

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P29 Manuka honey downregulates IL-4-induced CCL26 via activation of the aryl hydrocarbon receptor

Abdullah A Alangari, Matin Dokht Ashoori, Wisam Alwan, Brigitta Stockinger, Jonathan N Barker, Emma Wincent, Paola Di Meglio

doi : 10.1093/bjd/ljad174.050

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P30 Microsatellite instability in cutaneous squamous cell carcinoma

Georgie Holt, Christine Hayes, Rachel Phelps, Akhtar Husain, Christopher Lamb, Richard Gallon, Neil Rajan

doi : 10.1093/bjd/ljad174.051

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P31 Dissecting the epigenetic and transcriptional regulators in keloid scars

Stavroula Tekkela, Elena M Drudi, Tanya Shaw, Mike Philpott, Edel O’Toole, Emanuel Rognoni

doi : 10.1093/bjd/ljad174.052

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P32 Restoring the ageing skin barrier in vitro

Priya Garcha, Eleri Jones, Jennifer Shelley, Matthew Caley

doi : 10.1093/bjd/ljad174.053

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P33 Investigating the utility and exploring biological targets of micro-wound healing compounds in 2D and 3D skin models

Metka Gorkic, David Messenger, Linda Wainwright, John Connelly, Cleo L Bishop

doi : 10.1093/bjd/ljad174.054

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Review of treatments for toenail onychomycosis caused by dermatophytes

doi : 10.1093/bjd/ljad169

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Safety of treatment with guselkumab in clinical trials for up to 5 years in patients with moderate-to-severe plaque psoriasis

doi : 10.1093/bjd/ljad170

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The use of biosimilars for psoriasis in the UK and Ireland

doi : 10.1093/bjd/ljad172

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Creating the Scale of Alopecia Areata Distress to measure a wide range of negative emotional, social and relationship disease consequences in adults

doi : 10.1093/bjd/ljad175

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Finding treatments to reduce scaling in ichthyosis

doi : 10.1093/bjd/ljad177

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An oncogene-targeted therapy for Merkel cell carcinoma

doi : 10.1093/bjd/ljad171

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Better understand about circulating biomarkers and disease severity of chronic hand eczema and atopic dermatitis

doi : 10.1093/bjd/ljad173

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