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A novel treatment of diaper dermatitis in children and adults
Federica Dall’Oglio MD, PhD, Maria Letizia Musumeci MD, PhD, Davide Francesco Puglisi MD, Giuseppe Micali MD
doi : 10.1111/jocd.14091
Volume 20, Issue S1 p. 1-4
Diaper dermatitis (DD) is an acute inflammatory reaction, regardless of the cause, of the diaper-covered area. Topical skin barrier repair cosmetic products are the mainstay treatment to cure and/or prevent DD.
10% urea cream in senile xerosis: Clinical and instrumental evaluation
Francesco Lacarrubba MD, Anna Elisa Verz? MD, Franco Dinotta MD, Giuseppe Micali MD
doi : 10.1111/jocd.14093
Volume 20, Issue S1 p. 5-8
Moisturizers represent the mainstay of treatment of xerosis and related pruritus in elderly patients.
Topical oil formulation of plant extracts and vitamins as effective treatment for stretch marks and xerosis—An observational longitudinal study
Mariateresa Cantelli MD, Elisa Camela MD, Claudio Marasca MD, Giuseppina Fontanella MD, Chiara Blasio MD, Gabriella Fabbrocini MD
doi : 10.1111/jocd.14094
Volume 20, Issue S1 p. 9-13
Stretch marks are linear scars that result from elastic fiber destruction. They usually occur as the consequence of rapid change in the body mass (weight gain and loss, pregnancy, weightlifting), long-term steroid use, or endocrinopathies. Treatment is challenging and mainly based on topical and procedural therapies, although the standard of care is still under debate.
Treatment of cradle cap in infants with a new cosmetic non-steroidal gel cream: Clinical, laboratory, and instrumental evaluation
Giuseppe Micali MD, Nella Pulvirenti MD, PhD, Federica Dall’Oglio MD, PhD, Aurora Tedeschi MD, PhD, Enrica Quattrocchi MD, Francesco Lacarrubba MD
doi : 10.1111/jocd.14095
Volume 20, Issue S1 p. 14-17
Cradle cap is a benign and self-limiting variant of seborrheic dermatitis (SD) that can be distressing for parents.
Capryloyl glycine and soy isoflavonoids in hypertrichosis: An experimental and placebo-controlled clinical study
Mauro Barbareschi MD, Federico Benetti MS, Elisa Gaio MS, Luisa Angileri MD, Stefano Veraldi MD
doi : 10.1111/jocd.14096
Volume 20, Issue S1 p. 18-22
The management of acquired hypertrichosis (HT) is based on the search of the causes and subsequent specific treatment. However, simultaneous hair removal is important.
A novel treatment of intertrigo in athletes and overweight subjects
Anna Elisa Verz? MD, Maria Rita Nasca MD, PhD, Federica Dall’Oglio MD, PhD, Chiara Cosentino PharmD, Giuseppe Micali MD
doi : 10.1111/jocd.14097
Volume 20, Issue S1 p. 23-27
Intertrigo is a recurrent inflammatory dermatosis involving large/small body folds. Skin barrier products represent the mainstay of treatment in uncomplicated mild/moderate intertrigo.
A novel azelaic acid formulation for the topical treatment of inflammatory rosacea: A multicentre, prospective clinical trial
Federica Dall’Oglio MD, PhD, Aurora Tedeschi MD, PhD, Francesco Lacarrubba MD, Gabriella Fabbrocini MD, PhD, Nevena Skroza MD, PhD, Paolo Chiodini MS, Giuseppe Micali MD
doi : 10.1111/jocd.14098
Volume 20, Issue S1 p. 28-31
Topical azelaic acid (AzA) is a common treatment for mild/moderate inflammatory rosacea.
Effects of food supplements and a topical solution containing nanosilicon on skin hydration, barrier function, and elasticity
Norma Cameli MD, PhD, Martina Silvestri MD, Maria Mariano MD, Enzo Berardesca MD
doi : 10.1111/jocd.14099
Volume 20, Issue S1 p. 32-35
Silicon is an abundant element in the human body and plays an important role in the skin, taking part in the synthesis of collagen and glycosaminoglycans. The use of nanotechnology methods, which processes materials at an atomic and molecular scale, has allowed the development of nanosilicons.
Issue Information
doi : 10.1111/jocd.14053
Journal of Cosmetic DermatologyVolume 20, Issue 4 p. 1037-1038
JCD April 2021 Editorial/Commentary
Michael H. Gold MD
doi : 10.1111/jocd.14030
Journal of Cosmetic DermatologyVolume 20, Issue 4 p. 1039-1039
Koebnerization secondary to microblading
Emma Tierney BMBS, Gina M. Kavanagh BMBS
doi : 10.1111/jocd.13695
Journal of Cosmetic DermatologyVolume 20, Issue 4 p. 1040-1041
Aspiration: I don't do it and neither should you
Alexander Z. Rivkin MD
doi : 10.1111/jocd.13989
Journal of Cosmetic DermatologyVolume 20, Issue 4 p. 1042-1043
Aspiration is a safety maneuver prior to filler injection in widespread use throughout the world, despite an absence of scientific evidence to its efficacy. This editorial questions the practice from a logical as well as a scientific point of view.
History of sunscreen: An updated view
Yangmyung Ma MBBS, Jinah Yoo MBChB, MRCP, PG Dip (Clinical Dermatology), MSc (Immunology & Immunogenetics), MSc (Skin Ageing & Aesthetic Medicine)
doi : 10.1111/jocd.14004
Journal of Cosmetic DermatologyVolume 20, Issue 4 p. 1044-1049
With the global sunscreen market expected to reach $24.4 billion worldwide by 2029, this demonstrates the increasing awareness of the damaging effects of sunlight. Sunscreen has been gradually evolving, and new photoprotective ingredients are continuing to be produced in response to growing scientific evidence on the effect of solar radiation on the skin.
A systematic review on the skin whitening products and their ingredients for safety, health risk, and the halal status
Fatin N. M. Nordin, Atiqah Aziz, Zalina Zakaria, Che Wan Jasimah Wan Mohamed Radzi
doi : 10.1111/jocd.13691
Journal of Cosmetic DermatologyVolume 20, Issue 4 p. 1050-1060
Skin-whitening products are in the high trend of demand for skin beautifying and lightening. Sources of ingredients for cosmetics could be natural, semi-synthetic, and synthetic that may affect the halal status of a product. The lack of scientific evidence on the safety and risks of such ingredients is a major concern to many consumers.
A short review of alternative ingredients and technologies of inorganic UV filters
?rika Minuci Nery, Renata Miliani Martinez, Maria Valéria Robles Velasco, André Rolim Baby
doi : 10.1111/jocd.13694
Journal of Cosmetic DermatologyVolume 20, Issue 4 p. 1061-1065
The growing need to use sunscreens is a concrete reality, and it is associated with the increase in the population's awareness of the ultraviolet (UV) radiation damage. Inorganic UV filters promote the formation of particles/pigments film over the skin surface, reflecting, dispersing, and absorbing the radiation. Investigations of this class of filters demonstrate the emergence of alternative ingredients and new technologies.
Skin microbiota as a therapeutic target for psoriasis treatment: Trends and perspectives
Roberta B. Rigon PhD, Andréa C. P. de Freitas BPharm, Juliano L. Bicas PhD, Karina Cogo-Müller PhD, Alberto K. Kurebayashi BPharm, Renata F. Magalh?es PhD, Gislaine R. Leonardi PhD
doi : 10.1111/jocd.13752
Journal of Cosmetic DermatologyVolume 20, Issue 4 p. 1066-1072
Psoriasis is a chronic, immune-mediated disease that has a major negative impact on a patient's quality of life. Although several literature reviews indicate that skin microbiota may play an important role in the development and regulation of the immune and inflammatory response of psoriasis, few clinical studies are demonstrating the benefits of using pre-, pro- and synbiotics as a therapeutic alternative at the management of the disease. In this review, we showed the use of probiotic microorganisms that may contribute to skin homeostasis and compiled the clinical trials that demonstrate the effect of therapy with probiotics on patients with psoriasis, an important area for scientific exploration in dermatology and being the first review article to compile this information.
Dermatologic adverse reactions to proton-pump inhibitors: A synthetized review
Antoine Salloum MD, Dayana Nasr MD, Diane Maalouf MD
doi : 10.1111/jocd.13763
Journal of Cosmetic DermatologyVolume 20, Issue 4 p. 1073-1079
Proton-pump inhibitors (PPIs) are one of the most prescribed drugs. Their dermatological adverse reactions are multiple and vary in severity.
Psychodermatology of acne: Psychological aspects and effects of acne vulgaris
Caroline Stamu-O'Brien MD, Mohammad Jafferany MD, Simona Carniciu MD, PhD, Ayman Abdelmaksoud MD
doi : 10.1111/jocd.13765
Journal of Cosmetic DermatologyVolume 20, Issue 4 p. 1080-1083
Acne is a chronic inflammatory skin condition seen commonly in adolescence and young adulthood. Despite being a frequent and nonthreatening life condition, acne has a significant psychological impact and comorbidity.
Safety of combining cosmetic injectables with radiofrequency microneedling: A 4.5-year review
Jordan V. Wang MD, MBE, MBA, Alexander Valiga MD, Christian A. Albornoz MD, Roy G. Geronemus MD
doi : 10.1111/jocd.13954
Journal of Cosmetic DermatologyVolume 20, Issue 4 p. 1084-1085
Pairing energy-based treatments, including radiofrequency microneedling, with either injectable neuromodulators or soft-tissue fillers can be an effective therapy for facial rejuvenation. However, there remains concerns by some physicians that this combination may add new risks for adverse events. Theoretical risks of combining energy-based treatment with neuromodulator injections include unintentional spread, which may result in eyelid ptosis and asymmetry. Potential risks with soft-tissue fillers include unexpected loss of filler volume, necrosis, burn, and product migration. In order to shed more light on this topic, we performed a retrospective chart review of single-session facial treatments with radiofrequency microneedling and cosmetic injectables over a 4.5 year period. We found no documented adverse events recorded related to combination treatment. This is important information that adds to the patient safety literature.
Generalized essential telangiectasia treated with PDL
Emily Powell MD, Ramsey Markus MD, Cedar H. Malone MD
doi : 10.1111/jocd.13938
Journal of Cosmetic DermatologyVolume 20, Issue 4 p. 1086-1087
Generalized essential telangiectasia (GET) is a rare, clinically benign condition but a source of cosmetic concern for affected patients. There is a dearth of publications and known treatment options for GET. This case report reviews the clinical course of a 54-year-old woman who presented with a long-standing history of telangiectatic patches on her dorsal feet and ankles with progressive spread to the lower extremities consistent with GET. The patient proceeded with two pulsed dye laser (PDL) treatments and had complete resolution of her skin findings maintained at her 1.5-year follow-up appointment.
The role of sleep in telogen effluvium and trichodynia: A commentary in the context of the current pandemic
Ellen M.S. Xerfan MD, Monica L. Andersen PhD, Anamaria S. Facina MD, PhD, Sergio Tufik MD, PhD, Jane Tomimori MD PhD
doi : 10.1111/jocd.13929
Journal of Cosmetic DermatologyVolume 20, Issue 4 p. 1088-1090
Telogen effluvium (TE), a common hair disease, is supposed to be related to stress, which could be secondary to poor sleep. We call attention to the current COVID-19 pandemic, that is leading to an increase in the prevalence of sleep disturbances, and as a consequence, higher states of stress and anxiety, which are possible triggers for TE. In parallel, trichodynia is a sensorial symptom that is commonly related with hair diseases, including TE. We argue that substance P, a neuropeptide that has participation in the neuroinflammation and in the sleep regulation, may play a possible role in this scalp paresthesia. We suggest that there may be an association between this substrate and sleep, which can aggravate trichodynia and TE. Further studies on this subject could provide more evidence on these relationships, and help to improve the patients’ quality of life and management of the condition.
Lay rater evaluation of naturalness and first impression following treatment of lower face wrinkles with hyaluronic acid fillers
Steven Dayan MD, Sabrina Fabi MD, Alessandra Nogueira MD
doi : 10.1111/jocd.13927
Journal of Cosmetic DermatologyVolume 20, Issue 4 p. 1091-1097
Hyaluronic acid (HA) dermal fillers formulated with XpresHAn TechnologyTM were subjectively assessed by investigators and subjects.
High-velocity pneumatic injection of non-crosslinked hyaluronic acid for skin regeneration and scar remodeling: A retrospective analysis of 115 patients
Diane MacGillis MD, Yuri Vinshtok MD
doi : 10.1111/jocd.14002
Journal of Cosmetic DermatologyVolume 20, Issue 4 p. 1098-1103
Pneumatic-assisted high velocity jet injections are an alternative method for intradermal delivery of hyaluronic acid (HA) and demonstrated efficacy in dermal thickening and scar remodeling with minimal side effects.
Deletion of adipocytes induced by a novel device simultaneously delivering synchronized radiofrequency and hifem: Human histological study
David J. Goldberg MD, JD
doi : 10.1111/jocd.13970
Journal of Cosmetic DermatologyVolume 20, Issue 4 p. 1104-1109
Radiofrequency (RF) is commonly recognized treatment option for fat reduction, utilizing heat-induced adipocyte deletion. HIFEM treatment has been proven to be an effective tool for body shaping.
Clinical observation and dermoscopy evaluation of fractional CO2 laser combined with topical tranexamic acid in melasma treatments
Yan Qu PhD, Fengjuan Wang BS, Junru Liu MS, Xiujuan Xia BS
doi : 10.1111/jocd.13992
Journal of Cosmetic DermatologyVolume 20, Issue 4 p. 1110-1116
Melasma is an acquired refractory pigmentary disorder, which is a skin disease that predominantly affects females. This investigation aims to assess the efficacy of a low-power fractional CO2 laser combined with tranexamic acid (TXA) for melasma topical treatment with MASI and dermoscopy.
Efficacy and safety of triple wavelength laser hair reduction in skin types IV to V
E.P. Raj Kirit MBBS, DDVL, DNB, Aishwarya Sivuni MBBS, MD, Sridevi Ponugupati MBBS, MD, Michel H. Gold MD
doi : 10.1111/jocd.13995
Journal of Cosmetic DermatologyVolume 20, Issue 4 p. 1117-1123
Laser hair reduction is one of the most common laser procedures in dermatology. Laser systems available are Ruby at 694 nm, Alexandrite (755 nm), Diode (810nm), and Nd:YAG (1064 nm). Recently, devices presenting a combination of wavelengths have shown to produce high effective hair reduction with no related risks. This study was conducted with the Soprano Ice Platinum (Alma Lasers, GMBH, Germany) that emits a combination of three wavelengths at 755, 810, and 1064 nm in a single pulse.
Comparative Study between Nd-YAG laser, fractional CO2 Laser, and combined Nd-YAG with fractional CO2 Laser in the Management of keloid: clinical and molecular Study
Mona Soliman MD, Yasmeen Etman MSc, Amal AbdElhameed MD, Radwa Elsharaby MD, Abeer Tawfik MD, PhD
doi : 10.1111/jocd.13920
Journal of Cosmetic DermatologyVolume 20, Issue 4 p. 1124-1132
Fractional CO2 laser and Nd-YAG laser have been reported to have promising results in the management of keloids. So far, there have been no comparative studies between these laser modalities.
An evaluation of electrocoagulation and thermal diffusion following radiofrequency microneedling using an in vivo porcine skin model
Shaun Wootten BSE, Zosia E. Zawacki VMD, Lawrence Rheins PhD, Carol Meschter DVM, PhD, DACVP, Zoe Diana Draelos MD
doi : 10.1111/jocd.13690
Journal of Cosmetic DermatologyVolume 20, Issue 4 p. 1133-1139
Few studies exist that examined the role of radiofrequency microneedling (RFMN) in skin electrocoagulation. This research utilized a porcine model to understand bipolar dermal delivery from an RFMN device.
Early and maintained application of the secretion of Cryptomphalus aspersa (SCA) 40% improves cutaneous healing after ablative fractional laser in skin aging
Pablo Fernandez-Gonzalez MD, Maria Vitale MD, M. Teresa Truchuelo MD, PhD
doi : 10.1111/jocd.13720
Journal of Cosmetic DermatologyVolume 20, Issue 4 p. 1140-1145
Ablative fractional laser generates a regulated skin damage, which secondarily improves skin aging.
A comparison of the efficacy of silicone gel containing onion extract and aloe vera to silicone gel sheets to prevent postoperative hypertrophic scars and keloids
Watsachon Pangkanon MD, Putthiporn Yenbutra MD, Nanticha Kamanamool MD, Apichaya Tannirandorn MD, Montree Udompataikul MD
doi : 10.1111/jocd.13933
Journal of Cosmetic DermatologyVolume 20, Issue 4 p. 1146-1153
Hypertrophic scars and keloids are postsurgery problems. Some studies showed that onion extract and aloe vera might be beneficial for postoperative scars. However, few of the randomized clinical trials were investigated.
Therapeutic implications of topical cetirizine 1% in treatment of male androgenetic alopecia: A case-controlled study
Mohamed S. Zaky MD, Hassan Abo Khodeir MD, Hebat-Allah Ahmed MD, Mohamed L. Elsaie MD
doi : 10.1111/jocd.13940
Journal of Cosmetic DermatologyVolume 20, Issue 4 p. 1154-1159
Androgenetic alopecia (AGA) is the most common form of alopecia in men. Cetirizine, a second-generation H1 blocker, is known for its anti-inflammatory properties and its ability to decrease prostaglandin D2 (PGD2) production.
A comprehensive topical antioxidant inhibits oxidative stress induced by blue light exposure and cigarette smoke in human skin tissue
Mitchell Wortzman PhD, Diane B. Nelson RN, MPH
doi : 10.1111/jocd.13991
Journal of Cosmetic DermatologyVolume 20, Issue 4 p. 1160-1165
Skin damage from visible light predominantly results from exposure to the blue light spectrum (400-500 nm) which generates Reactive Oxygen Species (ROS) causing a cascade of harmful effects to skin. Topical antioxidants reduce the effects of free radical damage caused by environmental exposures. This study evaluated a comprehensive topical antioxidant's ability to inhibit ROS production induced by blue light and cigarette smoke (CS) in human skin.
Quality control of retinoids in commercial cosmetic products
?ane Temova Raku?a MS, Petja ?kufca BS, Albin Kristl PhD, Robert Ro?kar PhD
doi : 10.1111/jocd.13686
Journal of Cosmetic DermatologyVolume 20, Issue 4 p. 1166-1175
Retinoids are widely used in different cosmetic products because of general improvement of skin appearance. However, retinoid concentration in cosmetics is restricted, and one particular form–retinoic acid, is banned in cosmetics due to safety reasons.
Bleaching and skin-lightening practice among female students in South India: A cross-sectional survey
Soumya Jagadeesan MD, Feroze Kaliyadan MD, DNB, MNAMS, FIMSA, SCE-RCP, FRCP, Karalikkattil T. Ashique MBBS, DDVL, PGDHS, FRCP, Aditi Karunakaran Pharm D
doi : 10.1111/jocd.13689
Journal of Cosmetic DermatologyVolume 20, Issue 4 p. 1176-1181
Bleaching with skin-lightening preparations is a common practice in our society. Particularly, a practice simply known as “bleaching”—referring to application of skin-lightening chemicals including ammonia, hydrogen peroxide, and hypochlorite, repeated at intervals, as a salon-based or home-based procedure appears wide-spread among young females in India. However, there is limited medical literature on “bleaching.”
Internalized stigma: One of the main factors responsible for the psychosocial burden of melasma?
Birgül ?zkesici Kurt MD, Esra ?nan Do?an MD, Mikail ?zdemir MD, Erkan Alpsoy MD
doi : 10.1111/jocd.13697
Journal of Cosmetic DermatologyVolume 20, Issue 4 p. 1182-1187
Internalized stigma is the acceptance of negative stereotypes about the disease created by society and withdrawing self from society with emotions such as worthlessness and shame.
Potential use of medicinal plants from Argentinean highland as agent anti-photoaging
Mar?a Eugenia Orqueda PhD, Mar?a Alejandra Moreno PhD, Iris Catiana Zampini PhD, Karent Bravo PhD, Edison Osorio PhD, Mar?a Inés Isla PhD
doi : 10.1111/jocd.13701
Journal of Cosmetic DermatologyVolume 20, Issue 4 p. 1188-1196
The overexposure to sun ultraviolet (UV) radiation produce photoaging by effect of free radicals on lipid, protein, and nucleic acid or by direct activation of responsible enzymes of cleavage of extracellular matrix components (EMC).
Efficacy and tolerability of a cream containing modified glutathione (GSH-C4), beta-Glycyrrhetic, and azelaic acids in mild-to-moderate rosacea: A pilot, assessor-blinded, VISIA and ANTERA 3-D analysis, two-center study (The “Rosazel” Trial)
Federica Dall’Oglio MD, PhD, Mario Puviani MD, Massimo Milani MD, Giuseppe Micali MD
doi : 10.1111/jocd.13707
Journal of Cosmetic DermatologyVolume 20, Issue 4 p. 1197-1203
Rosacea is a very common, chronic inflammatory disease characterized by flushing, erythema and inflammatory lesions. Increased oxidative stress plays a relevant pathogenetic role in Rosacea. Intracellular Glutathione (GSH) is the main scavenger protective mechanism against increased oxidative stress. An altered GSH metabolism in Rosacea has been described. GSH-C4 is a modified GSH molecule characterized by a better intracellular bioavailability and longer half-life. A daily cream (E-AR) containing GSH-C4 (0.1%) with beta-Glycyrrhetic (0.5%) and azelaic acids (10%), with an SPF of 30, is available.
Permanent hair wavings: What dermatologists should know?
Taynara de Mattos Barreto MD, Flavia Weffort MD, Simone Carolina Frattini MSc, MD, Giselle Martins Pinto MSc, MD, Patricia dos Santos Damasco MD, Daniel Fernandes Melo MSc, MD
doi : 10.1111/jocd.13687
Journal of Cosmetic DermatologyVolume 20, Issue 4 p. 1204-1207
Hair represents an important aspect of human individuality. The possibility of having an easy to handle hairstyle and changing it from time to time promoted an increasing search for chemical hair transformations, including permanent wavings (PW). PW is the chemical process used to convert straight into curly hair. Significant findings have been made in this field within the last three decades. In the past few years, PW has come back up to date, helping to define curls in wavy and curly hair and to create waves in straight hair. “Afro permanent” and “Beach waves” are some popular names for these new uses of PW.
Will the patient’s double eyelid shape be like that of the surgeon performing the procedure? A study of surgeons’ aesthetics in East Asian Blepharoplasty
Hayson Chenyu Wang MD, PhD, Wenyun Ting MD, PhD, Dandan Tong PhD, Ruijia Dong MD, Xiao Long MD, PhD, Jiuzuo Huang MD, Hairu Cao MBBS, Elliot Tianyu Sun PhD, Nanze Yu MD, PhD, Xiaojun Wang MD, PhD, Ru Zhao MD, PhD
doi : 10.1111/jocd.13699
Journal of Cosmetic DermatologyVolume 20, Issue 4 p. 1208-1213
Background :No reports of the potential areas of surgeons' aesthetics in blepharoplasty.Aims:To explore the association between the surgeons' own double eyelid morphology and their aesthetics and surgical outcome.
Novel technique of non-surgical rejuvenation of infraorbital dark circles
Sabrina Shah-Desai MS, FRCS (Ed), Varajini Joganathan MSc, FRCOphth, FEBO
doi : 10.1111/jocd.13705
Journal of Cosmetic DermatologyVolume 20, Issue 4 p. 1214-1220
Infraorbital dark circles are a common esthetic concern which can be challenging to treat given their multifactorial nature. Under-eye dark circles are seen in all skin types, with a strong familial component in darker skin types. Other major contributing factors include soft tissue and bony changes, skin changes, lifestyle contributions, and allergies. Involutional periorbital volumetric changes cause volume loss in the tear trough, naso-jugal and palpebro-malar grove, skin and subcutaneous tissues with tethering of the eyelid skin to the tear trough ligament, giving a sunken and hollow appearance to the lower lid. Associated prolapse of the orbital fat and thin skin can worsen the appearance of a dark circle. Hyaluronic acid fillers placed in the pre-periosteal plane in the tear trough, palpebro-malar and naso-jugal grooves, give good results in patients with thick eyelid skin and negligible fat prolapse. However, in patients with thin skin and moderate fat prolapse, authors have reported worsening outcomes with risk of Tyndall (blue-gray discoloration) and contour irregularities from visible lumps.
Autologous activated platelet-rich plasma in hair growth: A pilot study in male androgenetic alopecia with in vitro bioactivity investigation
Yinghui Zhou MD, MSc, Qingmei Liu PhD, Yanshuang Bai MD, MSc, Kai Yang MD, MSc, Yaqi Ye MD, MSc, Kejia Wu MD, MSc, Junhong Huang MD, MSc, Yue Zhang MD, PhD, Xuewenjun Zhang MD, MSc, Traidit Thianthanyakij BCM, MBBS, MSc, Ji’an Wang MD, MSc, Yifei Zhu MD, MSc, Jinran Lin MD, PhD, Wenyu Wu MD, PhD
doi : 10.1111/jocd.13709
Journal of Cosmetic DermatologyVolume 20, Issue 4 p. 1221-1230
Background:Platelet-rich plasma (PRP) is effective in the treatment of androgenetic alopecia (AGA).Aims:The purpose of this study is to assess the effect of PRP on the proliferation of human follicle dermal papilla cells (HFDPCs), to observe the effect of PRP on the growth of hair follicles and hair shaft in vitro, to measure growth factors, and to evaluate the efficacy and safety of PRP injection.
Efficacy and safety of intralesional injection of vitamin D3 versus tuberculin PPD in the treatment of plantar warts: A comparative controlled study
Nahla Elsayed Ghaly, Amal Ahmad El-Ashmawy, Mai Abou Zeid, Engi Seif E. Shaker
doi : 10.1111/jocd.13712
Journal of Cosmetic DermatologyVolume 20, Issue 4 p. 1231-1240
Background:Several destructive and immunotherapeutic methods are used in treatment of plantar warts, but an effective method with no or reduced recurrence has not been found till now.Objectives:To evaluate the efficacy and safety of intralesional (IL) vitamin D3 (Vit.D3) injection vs IL tuberculin purified protein derivative (PPD) injection in the treatment of plantar warts.
Microneedling in androgenetic alopecia; comparing two different depths of microneedles
Gita Faghihi MD, Samin Nabavinejad MD, Fatemeh Mokhtari MD, Farahnaz Fatemi Naeini MD, Fariba Iraji MD
doi : 10.1111/jocd.13714
Journal of Cosmetic DermatologyVolume 20, Issue 4 p. 1241-1247
Background:Microneedling has shown to have positive therapeutic effects in treatment of androgenetic alopecia (AGA); however, the best microneedling protocol is still controversial.Aims:Investigating effect of microneedling with 2 different depths of penetration on promoting hair growth in patients with AGA.
Evaluation of intralesional Candida antigen in diabetic patients with multiple warts
Ayman Marei MD, PhD, Rania Alakad MD, Reham M. Wahid MD
doi : 10.1111/jocd.13718
Journal of Cosmetic DermatologyVolume 20, Issue 4 p. 1248-1253
Treatment of warts in diabetic patients with ablative modalities poses a significant risk owing to increased possibility of secondary infection, slow healing, and recurrence. Intralesional immunotherapy has gained popularity in the treatment of warts due to its proven efficacy and good tolerability compared with destructive methods.
Development of a multiphasic, cryptic screening protocol for body dysmorphic disorder in cosmetic dermatology
Leslie Fletcher MSN, RN, AGNP-BC
doi : 10.1111/jocd.13885
Journal of Cosmetic DermatologyVolume 20, Issue 4 p. 1254-1262
The incidence of body dysmorphic disorder in cosmetic dermatology is high. Even though treating patients with this disorder may worsen symptoms and is fraught with potential complications, screening is low, due in part to lack of knowledge of the disorder, as well as inadequate screening tools.
Predicting the risk of postinflammatory hyperpigmentation: The palmar creases pigmentation scale
Hector Leal-Silva MD, PhD
doi : 10.1111/jocd.13968
Journal of Cosmetic DermatologyVolume 20, Issue 4 p. 1263-1270
Postinflammatory hyperpigmentation (PIH) may affect any skin type but has been linked more often to darker skin. While propensity to hyperpigmentation has not been fully elucidated, there may be a direct correlation to one's palmar crease pigmentation.
Effect of grape seed extract on skin fibroblasts exposed to UVA light and its photostability in sunscreen formulation
Liudmila Yarovaya, Neti Waranuch, Wudtichai Wisuitiprot, Watcharee Khunkitti
doi : 10.1111/jocd.13711
Journal of Cosmetic DermatologyVolume 20, Issue 4 p. 1271-1282
Grape seed extract (GSE) is rich in polyphenolic compounds, particularly (+)-catechin (C) and (-)-epicatechin (EC). Strong antioxidant activity of these compounds makes GSE to be value-added to the cosmetics with anti-aging properties. However, a lack of stability in different environmental conditions makes GSE challenging for the development of photostable cosmetic sunscreen products.
In vivo and in vitro hair growth-promoting effect of silver and iron nanoparticles synthesized via Blumea eriantha DC plant extract
Rohankumar R. Chavan MPharm, Somnath D. Bhinge PhD, Mangesh A. Bhutkar PhD, Dheeraj S. Randive MPharm, Ganesh H. Wadkar PhD, Sachin S. Todkar Mpharm
doi : 10.1111/jocd.13713
Journal of Cosmetic DermatologyVolume 20, Issue 4 p. 1283-1297
Blumea eriantha DC is the Indian medicinal remedy, mainly distributed in the States of India. It possesses wide array of medicinal properties.
Serum levels of soluble PD1 in pemphigus vulgaris: A useful marker for disease severity
Ola Abu Zeid MD, Laila Rashed MD, Shimaa Khalifa MSc, Marwah Adly Saleh MD, PhD, Nanis Ragab MD
doi : 10.1111/jocd.13719
Journal of Cosmetic DermatologyVolume 20, Issue 4 p. 1298-1302
Pemphigus vulgaris (PV) is a life-threatening autoimmune blistering disease targeting the skin and mucous membranes. Programmed cell death protein 1 (PD1) is an immune checkpoint which binds to two ligands, PDL1 and PDL2 resulting in negative regulation of antigen receptor signaling, thus, play a critical role in the immune regulation of autoimmune diseases.
Exogenous nail and skin pigmentation associated with the artichoke (Cynara scolymus L.)
Sevil Sava? Erdo?an MD, Filiz Cebeci Kahraman MD
doi : 10.1111/jocd.13722
Journal of Cosmetic DermatologyVolume 20, Issue 4 p. 1303-1305
Nail dyschromia occurs for various reasons and presents with different clinical appearances. Exogenous causes, such as occupational agents, trauma, and infection can cause discoloration in the nail.
Single hair fiber assessment techniques to discriminate between mineral oil and coconut oil effect on hair physical properties
Vaibhav Kaushik, Ritesh Chogale, Sudhakar Mhaskar
doi : 10.1111/jocd.13724
Journal of Cosmetic DermatologyVolume 20, Issue 4 p. 1306-1317
To utilize a matrix of single-fiber hair testing methodologies to mechanistically understand the impact of common oiling treatments—coconut oil and mineral oil—on hair strands. Further, the effect of hair twisting—experienced in everyday grooming practices—on hair strength was investigated under different scenarios.
Implications of cigarette smoking on early-onset androgenetic alopecia: A cross-sectional Study
Ahmed S. Salem MD, Hany S. Ibrahim MD, Heba H. Abdelaziz MD, Mohamed L. Elsaie MD
doi : 10.1111/jocd.13727
Journal of Cosmetic DermatologyVolume 20, Issue 4 p. 1318-1324
Androgenetic alopecia (AGA) is a condition affecting both males and females. Aims We aimed to assess the demographic and clinical features of early-onset AGA among smokers and nonsmokers and to evaluate whether prevalence of AGA was affected by smoking.
Systemic dexpanthenol as a novel treatment for female pattern hair loss
?mer Kutlu MD, MRCP, EBDV, Ahmet Metin MD
doi : 10.1111/jocd.13729
Journal of Cosmetic DermatologyVolume 20, Issue 4 p. 1325-1330
There are only a few drugs that have been used for the treatment of female pattern hair loss (FPHL).
Interleukin 17 receptor A haplotype analysis in chronic spontaneous urticaria: A preliminary study
Hesham Nada MD, PhD, Ranya Hassan MD, PhD, Rasha Abd El-Hamed Ibrahim MSc, Omnia Emad Abdelsalam MSc, Amal Fathy MD, Eman Ali Toraih MD, PhD, Mona A. Atwa MD
doi : 10.1111/jocd.13730
Journal of Cosmetic DermatologyVolume 20, Issue 4 p. 1331-1342
Chronic spontaneous urticaria (CSU) is a distressing skin disease. Family clustering and heterogeneity in the onset and progression indicate that susceptibility to CSU is a complex trait. In this study, we performed haplotype analysis for one of the key player gene, IL17RA, for CSU to test the association with disease susceptibility and severity.
Resurfacing with a new 675-nm laser device: A case series
Domenico Piccolo MD, Dimitra Kostaki MD, Giuliana Crisman MD, Claudio Conforti MD
doi : 10.1111/jocd.13916
Journal of Cosmetic DermatologyVolume 20, Issue 4 p. 1343-1345
no abstract
Saline in dermatologic surgery
Tamara Searle BSc, Firas Al-Niaimi MRCP, Faisal R. Ali MRCP
doi : 10.1111/jocd.13996
Journal of Cosmetic DermatologyVolume 20, Issue 4 p. 1346-1347
no abstract
Ethical-legal evaluation of the use of placebo in clinical trials
Renata Zareba MD, Edyta Rysiak PhD, Andrzej Przylipiak PhD, Ilona Oscilowska PhD
doi : 10.1111/jocd.13967
Journal of Cosmetic DermatologyVolume 20, Issue 4 p. 1348-1349
no abstract
Novel cannabidiol sunscreen protects keratinocytes and melanocytes against ultraviolet B radiation
Pranjal Gohad MS, PhD, John McCoy PhD, Carlos Wambier MD, PhD, Maja Kovacevic MD, Mirna Situm MD, Andrija Stanimirovic MD, PhD, Andy Goren MD
doi : 10.1111/jocd.13693
Journal of Cosmetic DermatologyVolume 20, Issue 4 p. 1350-1352
Cannabidiol (CBD), a natural occurring phytocannabinoid, is used extensively in consumer products ranging from foods to shampoos, topical oils and lotions. Several studies demonstrated the anti-inflammatory and antioxidative properties of cannabidiol. Nevertheless, the role of cannabidiol use in sunscreens is largely unknown as no studies on its effect on keratinocytes or melanocytes exist. As such, we aimed to explore the effect of CBD on keratinocyte and melanocyte viability following ultraviolet B (UVB) irradiation. CBD exhibited a dose-dependent protective effect on both keratinocytes and melanocyte viability. Further, since CBD does not demonstrate absorption in the UVB spectra, we speculate that the protective effect is due to reduction in reactive oxygen species. To our knowledge, this is the first study demonstrating the protective effect of CBD on keratinocytes and melanocytes irradiated with UVB.
Granulomatous periorificial dermatitis with a dramatic response methotrexate treatment
Gulcan Saylam Kurtipek MD, Fatma Tuncez Akyurek MD, Mehmet Akyurek MD, Nihal Sar? MD, Pinar Karabagli MD, d
doi : 10.1111/jocd.13706
Journal of Cosmetic DermatologyVolume 20, Issue 4 p. 1353-1354
no abstract
Laser-assisted topical steroid application vs steroid injection for treating keloids: A split side study
Xinhang Dong MD, Mingzi Zhang MD, Chengcheng Li MD, Xiaolei Jin MD
doi : 10.1111/jocd.13964
Journal of Cosmetic DermatologyVolume 20, Issue 4 p. 1355-1356
no abstract
