دسترسی یکساله به بیش از ۵۰۰ ژورنال روز جهان موجود در سامانه
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Effect of Low-Intensity vs High-Intensity Home-Based Walking Exercise on Walk Distance in Patients With Peripheral Artery DiseaseThe LITE Randomized Clinical Trial
Mary M. McDermott, MD; Bonnie Spring, PhD; Lu Tian, ScD; et al.
doi : 10.1001/jama.2021.2536
JAMA. 2021;325(13):1266-1276.
This randomized trial compares the effects of comfortable low-intensity home-based walking exercise vs high-intensity exercise sufficient to elicit ischemic symptoms vs nonexercise control on 6-minute walk distance among patients with peripheral arterial disease (PAD).
Effect of Celecoxib vs Placebo Added to Standard Adjuvant Therapy on Disease-Free Survival Among Patients With Stage III Colon CancerThe CALGB/SWOG 80702 (Alliance) Randomized Clinical Trial
Jeffrey A. Meyerhardt, MD, MPH; Qian Shi, PhD; Charles S. Fuchs, MD, MPH; et al.
doi : 10.1001/jama.2021.2454
JAMA. 2021;325(13):1277-1286.
This randomized trial compares the effect of adding celecoxib to standard adjuvant chemotherapy in improving disease-free survival among patients treated for stage III colon cancer.
Antimicrobial Use in a Cohort of US Nursing Homes, 2017
Nicola D. Thompson, MS, PhD; Nimalie D. Stone, MD; Cedric J. Brown, MS; et al.
doi : 10.1001/jama.2021.2900
JAMA. 2021;325(13):1286-1295.
This cross-sectional survey assessed the risks of antimicrobial use among 15?276 nursing home residents across 161 facilities.
Emergence of a Novel SARS-CoV-2 Variant in Southern California
Wenjuan Zhang, PhD; Brian D. Davis, BSc; Stephanie S. Chen, BSc; et al.
doi : 10.1001/jama.2021.1612
JAMA. 2021;325(13):1324-1326.
This research describes findings of sequencing and phylogenetic analyses of SARS-CoV-2 isolates from symptomatic patients cared for at Cedar-Sinai Medical Center in November-December 2020 during a regional surge in cases and hospitalizations.
Changes in Shooting Incidence in Philadelphia, Pennsylvania, Between March and November 2020
Jessica H. Beard, MD, MPH; Sara F. Jacoby, PhD, MPH; Zoë Maher, MD; et al.
doi : 10.1001/jama.2021.1534
JAMA. 2021;325(13):1327-1328.
This study uses police department registry data to describe trends in incidence of firearm shootings and deaths in January-November 2020, before and after the closure of nonessential businesses in March, the killing of George Floyd in May, and the partial lifting of containment policies in June.
Trends in Age at Natural Menopause and Reproductive Life Span Among US Women, 1959-2018
Duke Appiah, PhD, MPH; Chike C. Nwabuo, MD, MPH; Imo A. Ebong, MD, MS; et al.
doi : 10.1001/jama.2021.0278
JAMA. 2021;325(13):1328-1330.
This national survey study uses the National Health and Nutrition Examination Survey (NHANES) to describe trends in age at natural menopause, age at menarche, and reproductive life span, and variables associated with shorter and longer spans, among US women between 1959-1962 and 2015-2018.
Reinventing the Center for Medicare and Medicaid Innovation
Donald M. Berwick, MD; Rick Gilfillan, MD
doi : 10.1001/jama.2021.3203
JAMA. 2021;325(13):1247-1248.
This Viewpoint makes 6 recommendations for how the Center for Medicare and Medicaid Innovation, as it enters its second decade, can better fulfill its mission of testing health care payment and service delivery models and scale them up to a national level to reduce health care expenditures and improve quality and safety.
The Potential Future of the COVID-19 PandemicWill SARS-CoV-2 Become a Recurrent Seasonal Infection?
Christopher J. L. Murray, MD; Peter Piot, MD
doi : 10.1001/jama.2021.2828
JAMA. 2021;325(13):1249-1250.
This Viewpoint discusses the prospect that COVID-19 could become a recurrent seasonal disease like influenza and proposes strategies to mitigate the consequences for communities and health systems, including changes in surveillance, medical and public health response, and socioeconomic programs.
Approaches for Optimal Use of Different COVID-19 VaccinesIssues of Viral Variants and Vaccine Efficacy
John P. Moore, PhD
doi : 10.1001/jama.2021.3465
JAMA. 2021;325(13):1251-1252.
This Viewpoint proposes ways to maximize vaccine efficacy and allocation given the rise of coronavirus variants and authorization of a Johnson & Johnson vaccine, including reserving the latter for younger healthier populations, boosting it with a single-dose messenger RNA (mRNA) vaccination, and single mRNA immunization of people with prior documented SARS-CoV-2 infection.
The Future of Health Policy in a Partisan United StatesInsights From Public Opinion Polls
Robert J. Blendon, ScD; John M. Benson, MA; Eric C. Schneider, MD
doi : 10.1001/jama.2021.1147
JAMA. 2021;325(13):1253-1254.
This Viewpoint summarizes views measured in national opinion polls about COVID-19 response, national health insurance reform, reforming the US health care system in general, and race and race disparities in health, with a focus on differences between Democrat and Republican respondents and implications of those differences for enacting meaningful legislation.
Sitting in the River
Jessi Humphreys, MD
doi : 10.1001/jama.2021.3857
JAMA. 2021;325(13):1255-1256.
In this narrative medicine essay, a palliative care physician finds the space between professional and patient distance thinning as the COVID pandemic drags on and wonders whether abiding with them is the lesson.
Celecoxib for Stage III Colon Cancer
David J. Kerr, MD, DSc; Sarah Chamberlain, BMedSci, MBChB; Rachel S. Kerr, MBChB, PhD
doi : 10.1001/jama.2021.2651
JAMA. 2021;325(13):1257-1258.
Opportunities to Improve Antimicrobial Use in US Nursing Homes
Christopher J. Crnich, MD, PhD; Preeti Malani, MD, MSJ
doi : 10.1001/jama.2021.3258
JAMA. 2021;325(13):1259-1260.
SARS-CoV-2 Viral Variants—Tackling a Moving Target
John R. Mascola, MD; Barney S. Graham, MD, PhD; Anthony S. Fauci, MD
doi : 10.1001/jama.2021.2088
JAMA. 2021;325(13):1261-1262.
To JAMA Authors, Reviewers, and Especially Physician Readers—A Profound Thank You
Phil B. Fontanarosa, MD, MBA; Howard Bauchner, MD; Robert Golub, MD
doi : 10.1001/jama.2021.3860
JAMA. 2021;325(13):1263-1265.
Filtering Facepiece Respirator (N95 Respirator) ReprocessingA Systematic Review
Max A. Schumm, MD; Joseph E. Hadaya, MD; Nisha Mody, MLIS, MA, CCC-SLP; et al.
doi : 10.1001/jama.2021.2531
JAMA. 2021;325(13):1296-1317.
In the context of widespread reuse and reprocessing of N95 respirators due to shortages caused by the COVID-19 pandemic, this systematic review summarizes evidence on effectiveness and feasibility of 5 decontaminating processes: UV irradiation, vaporized hydrogen peroxide, moist-heat incubation, microwave-generated steam, and ethylene oxide.
SARS-CoV-2 Vaccines
C. Buddy Creech, MD, MPH; Shannon C. Walker, MD; Robert J. Samuels, MBChB
doi : 10.1001/jama.2021.3199
JAMA. 2021;325(13):1318-1320.
This JAMA Insights clinical review explains different approaches to SARS-CoV-2 vaccine development, including inactivated and protein subunit, viral vector, and mRNA immunization strategies, and summarizes safety and efficacy data for global products authorized for use or in later-stage clinical trials.
Drugs for Atopic Dermatitis
doi : 10.1001/jama.2020.11192
JAMA. 2021;325(13):1321-1322.
This Medical Letter provides a Table summarizing key information about topical corticosteroids available for atopic dermatitis published as part of a comprehensive review on the topic.
COVID-19 Vaccines vs Variants—Determining How Much Immunity Is Enough
Rita Rubin, MA
doi : 10.1001/jama.2021.3370
JAMA. 2021;325(13):1241-1243.
This Medical News feature examines what is known about the efficacy of COVID-19 vaccines against SARS-CoV-2 variants.
Experts Discuss COVID-19—Vaccine Questions, School Openings, and More
doi : 10.1001/jama.2021.4121
JAMA. 2021;325(13):1244-1245.
This Medical News article is a roundup of insights from recent livestream interviews with leading experts.
A First in Surgical Devices for Transvaginal Hysterectomy
Rebecca Voelker, MSJ
doi : 10.1001/jama.2021.4592
JAMA. 2021;325(13):1246.
3D-Printed Implant Is Approved to Replace Ankle Joint Bone
Rebecca Voelker, MSJ
doi : 10.1001/jama.2021.4029
JAMA. 2021;325(13):1246.
Thermal Imaging Systems May Pose Public Health Risks
Rebecca Voelker, MSJ
doi : 10.1001/jama.2021.4594
JAMA. 2021;325(13):1246.
Whistleblowing and Misconduct at Large Pharmaceutical Firms
Takanao Hashimoto, PhD; Akihiko Ozaki, MD, PhD; Tetsuya Tanimoto, MD
doi : 10.1001/jama.2021.0573
JAMA. 2021;325(13):1331.
Whistleblowing and Misconduct at Large Pharmaceutical Firms—Reply
Denis G. Arnold, PhD; Tammy Beck, PhD; Oscar Jerome Stewart, PhD
doi : 10.1001/jama.2021.0576
JAMA. 2021;325(13):1331-1332.
Omega-3 Fatty Acids Effect on Major Cardiovascular Events in Patients at High Cardiovascular Risk
Brian Olshansky, MD; Deepak L. Bhatt, MD; Mina K. Chung, MD
doi : 10.1001/jama.2021.0824
JAMA. 2021;325(13):1332-1333.
Omega-3 Fatty Acids Effect on Major Cardiovascular Events in Patients at High Cardiovascular Risk
Francine Welty, MD, PhD; Bruce Bistrian, MD, PhD; David Driscoll, PhD
doi : 10.1001/jama.2021.0830
JAMA. 2021;325(13):1333.
Omega-3 Fatty Acids Effect on Major Cardiovascular Events in Patients at High Cardiovascular Risk
Yutang Wang, PhD
doi : 10.1001/jama.2021.0821
JAMA. 2021;325(13):1333.
Omega-3 Fatty Acids Effect on Major Cardiovascular Events in Patients at High Cardiovascular Risk
Kye-Yeung Park, MD, PhD; Hoon-Ki Park, MD, PhD; Hwan-Sik Hwang, MD, PhD
doi : 10.1001/jama.2021.0827
JAMA. 2021;325(13):1334.
Omega-3 Fatty Acids Effect on Major Cardiovascular Events in Patients at High Cardiovascular Risk—Reply
Steven E. Nissen, MD; A. Michael Lincoff, MD; Stephen J. Nicholls, MBBS, PhD
doi : 10.1001/jama.2021.0839
JAMA. 2021;325(13):1334-1335.
