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Effect of Intermediate-Dose vs Standard-Dose Prophylactic Anticoagulation on Thrombotic Events, Extracorporeal Membrane Oxygenation Treatment, or Mortality Among Patients With COVID-19 Admitted to the Intensive Care UnitThe INSPIRATION Randomized Clinical Trial
INSPIRATION Investigators
doi : 10.1001/jama.2021.4152
JAMA. 2021;325(16):1620-1630.
This randomized trial compares the effect of intermediate-dose vs standard prophylactic enoxaparin on a composite outcome of acute venous thromboembolism (VTE), arterial thrombosis, need for extracorporeal membrane oxygenation (ECMO), and all-cause mortality within 30 days among patients with COVID-19 admitted to the ICU.
Hospital Quality Improvement Interventions, Statewide Policy Initiatives, and Rates of Cesarean Delivery for Nulliparous, Term, Singleton, Vertex Births in California
Melissa G. Rosenstein, MD, MAS; Shen-Chih Chang, MS, PhD; Christa Sakowski, MSN; et al.
doi : 10.1001/jama.2021.3816
JAMA. 2021;325(16):1631-1639.
This population epidemiology study compares rates of cesarean delivery for nulliparous, term, singleton, vertex (NTSV) births in California before vs after a statewide intervention to reduce cesarean deliveries and compares trends in California with those in the US.
Association Between Age at Diabetes Onset and Subsequent Risk of Dementia
Claudio Barbiellini Amidei, MD; Aurore Fayosse, MSc; Julien Dumurgier, PhD; et al.
doi : 10.1001/jama.2021.4001
JAMA. 2021;325(16):1640-1649.
This cohort study uses UK Whitehall cohort data to examine the association between age at type 2 diabetes onset and incident dementia.
HPV Vaccination Among Young Adults in the US
Michelle M. Chen, MD, MHS; Nicole Mott, BS; Sarah J. Clark, MPH; et al.
doi : 10.1001/jama.2021.0725
JAMA. 2021;325(16):1673-1674.
This study uses data from the 2010-2018 National Health Interview Survey to characterize trends in human papillomavirus (HPV) vaccination rates, ages at vaccination, and numbers of doses received among young adults in the US between 2010 and 2018.
Out-of-Network Laboratory Test Spending, Utilization, and Prices in the US
Zirui Song, MD, PhD; Timothy Lillehaugen, MPH; Jacob Wallace, PhD
doi : 10.1001/jama.2021.0720
JAMA. 2021;325(16):1674-1676.
In the context of concerns about the appropriateness and costs to insurers and patients of laboratory testing, this study uses data from the IBM MarketScan Commercial Claims and Encounters Database to examine out-of-network laboratory test spending, utilization, and prices in the US in 2008-2016.
Reasons for Admissions to US Children’s Hospitals During the COVID-19 Pandemic
Peter J. Gill, MD, DPhil; Sanjay Mahant, MD, MSc; Matt Hall, PhD; et al.
doi : 10.1001/jama.2021.4382
JAMA. 2021;325(16):1676-1679.
This study uses Pediatric Health Information System database data to compare hospitalizations in US children’s hospitals early in the COVID-19 pandemic (March-August 2020) vs the same period in 2017-2019, overall and for respiratory, chronic, nonrespiratory, and other conditions.
Screening for Hypertension in AdultsUS Preventive Services Task Force Reaffirmation Recommendation Statement
US Preventive Services Task Force
doi : 10.1001/jama.2021.4987
JAMA. 2021;325(16):1650-1656.
This 2021 US Preventive Services Task Force Reaffirmation Recommendation Statement recommends screening for hypertension in adults 18 years or older with office blood pressure measurement and obtaining blood pressure measurements outside of the clinical setting for diagnostic confirmation before starting treatment (A recommendation).
Screening for Hypertension in AdultsUpdated Evidence Report and Systematic Review for the US Preventive Services Task Force
Janelle M. Guirguis-Blake, MD; Corinne V. Evans, MPP; Elizabeth M. Webber, MS; et al.
doi : 10.1001/jama.2020.21669
JAMA. 2021;325(16):1657-1669.
This systematic review to support the 2021 US Preventive Services Task Force Recommendation Statement on screening for hypertension summarizes published evidence on the benefits and harms of hypertension screening and confirmatory blood pressure measurements in adults 18 years or older without known hypertension.
Prioritizing Nutrition Security in the US
Dariush Mozaffarian, MD, DrPH; Sheila Fleischhacker, PhD, JD, RDN; José R. Andrés
doi : 10.1001/jama.2021.1915
JAMA. 2021;325(16):1605-1606.
This Viewpoint addresses nutrition security—defined as having consistent access, availability, and affordability of foods and beverages that promote well-being and prevent or even treat disease—and its importance to clinical care and public policy in the US.
The Interstate Medical Licensure CompactAttending to the Underserved
Eli Y. Adashi, MD, MS; I. Glenn Cohen, JD; Winston L. McCormick, BS
doi : 10.1001/jama.2021.1085
JAMA. 2021;325(16):1607-1608.
This Viewpoint reviews the creation of the US Interstate Medical Licensure Compact (IMLC), which facilitates licensure for physicians who wish to practice in multiple states with the aim of increasing access to care for patients in underserved areas and emphasizes its growing importance to states and physicians given more widespread use of telemedicine.
State Medical Board Recommendations for Stronger Approaches to Sexual Misconduct by Physicians
Patricia A. King, MD, PhD; Humayun J. Chaudhry, DO, MS; Mark L. Staz, MA
doi : 10.1001/jama.2020.25775
JAMA. 2021;325(16):1609-1610.
This Viewpoint discusses recommendations adopted by the US Federation of State Medical Boards (FSMB) to guide state boards on how to respond to reports of sexual misconduct by physicians toward patients, including harassment and abuse.
Becoming a Mother and Gaining Perspective
Lauren Rissman, MD
doi : 10.1001/jama.2021.5160
JAMA. 2021;325(16):1611-1612.
In this narrative medicine essay, a pediatric intensive care fellow tells of her near death from postpartum hemorrhage in childbirth, her first delayed introduction to her daughter, and her struggle with helplessness in caring for her premature daughter during her convalescence.
Finding the Optimal Thromboprophylaxis Dose in Patients With COVID-19
Hanny Al-Samkari, MD
doi : 10.1001/jama.2021.4295
JAMA. 2021;325(16):1613-1615.
Initiatives to Reduce Cesarean Delivery Rates for Low-risk First Births
David B. Nelson, MD; Catherine Y. Spong, MD
doi : 10.1001/jama.2021.0084
JAMA. 2021;325(16):1616-1617.
The USPSTF Recommendation on Blood Pressure ScreeningMaking 2021 the Transformative Year in Controlling Hypertension
Marwah Abdalla, MD, MPH; Paul Muntner, PhD; Eric D. Peterson, MD, MPH
doi : 10.1001/jama.2021.4499
JAMA. 2021;325(16):1618-1619.
First-Dose COVID-19 Vaccination Coverage Among Skilled Nursing Facility Residents and Staff
Radhika Gharpure, DVM, MPH; Anita Patel, PharmD, MS; Ruth Link-Gelles, PhD, MPH
doi : 10.1001/jama.2021.2352
JAMA. 2021;325(16):1670-1671.
This JAMA Insights review from CDC COVID-19 Response team members presents data on the number of long-term care facilities and the numbers of residents and staff of those facilities who received first-dose vaccination through mid-January 2021 under the agency’s public-private partnership with CVS, Walgreens, and Managed Health Care Associates.
How Sharing Clinical Notes Affects the Patient-Physician Relationship
Rita Rubin, MA
doi : 10.1001/jama.2021.4755
JAMA. 2021;325(16):1596-1598.
This Medical News feature describes the impact of open visit notes on patient care.
To Address Drug Affordability, Grab the Low-hanging Fruit
Michelle M. Mello, JD, PhD, MPhil; Trish Riley, MS
doi : 10.1001/jama.2021.4619
JAMA. 2021;325(16):1599-1600.
Israel’s Real-life Evidence That Vaccine Can Prevent Severe COVID-19
Bridget M. Kuehn, MSJ
doi : 10.1001/jama.2021.5617
JAMA. 2021;325(16):1603.
More Severe Obesity Leads to More Severe COVID-19 in Study
Bridget M. Kuehn, MSJ
doi : 10.1001/jama.2021.4853
JAMA. 2021;325(16):1603.
N-of-1 Trial Finds No Effect of Statins on Muscle Symptoms
Anita Slomski, MA
doi : 10.1001/jama.2021.4801
JAMA. 2021;325(16):1602.
Relugolix Combination Therapy for Uterine Fibroids
Anita Slomski, MA
doi : 10.1001/jama.2021.5857
JAMA. 2021;325(16):1602.
Low-Income African American Women With Hypertension and Depression
Anita Slomski, MA
doi : 10.1001/jama.2021.5861
JAMA. 2021;325(16):1602.
Bimekizumab Offers Rapid and Durable Psoriasis Treatment
Anita Slomski, MA
doi : 10.1001/jama.2021.5863
JAMA. 2021;325(16):1602.
Vaccination Priorities Delay Shots for Higher-Risk People of Color
Rita Rubin, MA
doi : 10.1001/jama.2021.5115
JAMA. 2021;325(16):1601.
NIH Launches Program to Investigate COVID-19 in Children
Rita Rubin, MA
doi : 10.1001/jama.2021.5880
JAMA. 2021;325(16):1601.
Medicare Raises Payment for Administering COVID-19 Vaccines
Rita Rubin, MA
doi : 10.1001/jama.2021.5882
JAMA. 2021;325(16):1601.
Screening for Hypertension in Adults
Jill Jin, MD, MPH
doi : 10.1001/jama.2021.5288
JAMA. 2021;325(16):1688.
This JAMA Patient Page summarizes the US Preventive Services Task Force’s 2021 recommendation that all adults aged 18 years or older be screened for high blood pressure (A statement).
Depression and Incident Cardiovascular Disease
Ibrahim El-Battrawy, MD; Michael Behnes, MD; Ibrahim Akin, MD
doi : 10.1001/jama.2021.2029
JAMA. 2021;325(16):1679-1680.
Depression and Incident Cardiovascular Disease—Reply
Karina W. Davidson, PhD; Lisa Pennells, PhD, MSc; Emanuele Di Angelantonio, MD, PhD
doi : 10.1001/jama.2021.2032
JAMA. 2021;325(16):1680.
Digoxin vs Bisoprolol for Heart Rate Control in Atrial Fibrillation
Jalaj Garg, MD; Rakesh Gopinathannair, MD, MA; Dhanunjaya Lakkireddy, MD
doi : 10.1001/jama.2021.2673
JAMA. 2021;325(16):1680-1681.
Digoxin vs Bisoprolol for Heart Rate Control in Atrial Fibrillation—Reply
Dipak Kotecha, MD, PhD, MSc
doi : 10.1001/jama.2021.2676
JAMA. 2021;325(16):1681-1682.
