JAMA

دسترسی یکساله به بیش از ۵۰۰ ژورنال روز جهان موجود در سامانه

ﻣﺪﺕ ﺯﻣﺎﻥ : 365 ﺭﻭﺯ
~~قیمت : 3,800,000 تومان~~
قیمت ویژه : 1,900,000تومان

سفارش

Effect of Convalescent Plasma Therapy on Time to Clinical Improvement in Patients With Severe and Life-threatening COVID-19A Randomized Clinical Trial

Ling Li, MD, PhD; Wei Zhang, MD; Yu Hu, MD, PhD; et al.

doi : 10.1001/jama.2020.10044

JAMA. 2020;324(5):471-480.

This randomized trial compares the effects of convalescent plasma therapy with standard care vs standard care alone on time to clinical improvement among patients with severe or life-threatening COVID-19 disease in China.

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Effect of Long-term Vitamin D3 Supplementation vs Placebo on Risk of Depression or Clinically Relevant Depressive Symptoms and on Change in Mood ScoresA Randomized Clinical Trial

Olivia I. Okereke, MD, SM; Charles F. Reynolds III, MD; David Mischoulon, MD, PhD; et al.

doi : 10.1001/jama.2020.10224

JAMA. 2020;324(5):481-487.

This randomized clinical trial compares the effects of vitamin D? supplementation vs placebo on depression risk and mood scores in men and women aged 50 years or older.

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Association of Diagnosis Coding With Differences in Risk-Adjusted Short-term Mortality Between Critical Access and Non–Critical Access Hospitals

Cyrus M. Kosar, MA; Lacey Loomer, PhD, MSPH; Kali S. Thomas, PhD; et al.

doi : 10.1001/jama.2020.9935

JAMA. 2020;324(5):481-487.

This study uses Medicare data to estimate mortality differences for common medical conditions (pneumonia, heart failure, chronic obstructive pulmonary disease, urinary tract infection, others) at US critical access vs non–critical access hospitals between 2007 and 2017 with vs without adjustment for discharge diagnosis counts to assess the extent to which coding practices rather than illness severity might account for observed mortality differences.

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Mortality, Admissions, and Patient Census at SNFs in 3 US Cities During the COVID-19 Pandemic

Michael L. Barnett, MD, MS; Lissy Hu, MD; Thomas Martin, MS; et al.

doi : 10.1001/jama.2020.11642

JAMA. 2020;324(5):507-509.

This study uses Medicare’s Nursing Home Compare and a university long-term care database to compare census, admissions, discharges, and mortality at skilled nursing facilities (SNFs) in 3 metropolitan areas during March-May 2020 vs March-May 2019.

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Excess Deaths From COVID-19 and Other Causes, March-April 2020

Steven H. Woolf, MD, MPH; Derek A. Chapman, PhD; Roy T. Sabo, PhD; et al.

doi : 10.1001/jama.2020.11787

JAMA. 2020;324(5):510-513.

This study uses data from the National Center for Health Statistics to estimate excess deaths (ie, the difference between observed and expected deaths) in the US and the District of Columbia in the early weeks of the COVID-19 pandemic.

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Prevalence, Characteristics, and Costs of Urgent Care Center Membership Programs

Walter Hsiang, BS; Grace Jin, BS; Howard Forman, MD, MBA; et al.

doi : 10.1001/jama.2020.7317

JAMA. 2020;324(5):513-514.

This study uses simulated patient phone calls to a random selection of US urgent care clinics (UCCs) to describe the proportion that offer membership programs with access to discounted visits for recurring fees and the characteristics (affiliations, accreditations, population income) and fees and charges of those that do.

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Academic Medicine and Black Lives MatterTime for Deep Listening

Clyde W. Yancy, MD, MSc

doi : 10.1001/jama.2020.12532

JAMA. 2020;324(5):435-436.

In the context of the Black Lives Matter movement, this Viewpoint considers the demand that academic medicine address its own structural racism, and concludes on the basis of its history, culture, role, and influence that the institution can, should, and must make racial justice a part of its work and mission.

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Developing a SARS-CoV-2 Vaccine at Warp Speed

Kevin P. O’Callaghan, MB, BCh, BAO; Allison M. Blatz, MD; Paul A. Offit, MD

doi : 10.1001/jama.2020.12190

JAMA. 2020;324(5):437-438.

This Viewpoint discusses the mechanisms of the 5 leading COVID-19 vaccine candidates—2 messenger RNA vaccines, 1 recombinant VSV vector product, and 2 replication-defective adenovirus vector approaches—and emphasizes the need to demonstrate safety as well as efficacy to facilitate broad uptake by the public.

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The Development of COVID-19 VaccinesSafeguards Needed

Nicole Lurie, MD, MSPH; Joshua M. Sharfstein, MD; Jesse L. Goodman, MD, MPH

doi : 10.1001/jama.2020.12461

JAMA. 2020;324(5):439-440.

This Viewpoint lists 4 safeguards policy makers should consider before release of a COVID-19 vaccine, including ensuring effectiveness through clinical trials, providing evidence of safety, requiring informed consent before vaccination, and establishing comprehensive adverse effects monitoring systems.

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Airborne Transmission of SARS-CoV-2Theoretical Considerations and Available Evidence

Michael Klompas, MD, MPH; Meghan A. Baker, MD, ScD; Chanu Rhee, MD, MPH

doi : 10.1001/jama.2020.12458

JAMA. 2020;324(5):441-442.

This Viewpoint discusses physical and epidemiological evidence supporting droplet vs aerosol transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), and concludes on balance that aerosol transmission seems unlikely to be the dominant mode of coronavirus disease 2019 (COVID-19) spread.

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Communicating Science in the Time of a Pandemic

Richard Saitz, MD, MPH; Gary Schwitzer

doi : 10.1001/jama.2020.12535

JAMA. 2020;324(5):443-444.

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Challenges Estimating Total Lives Lost in COVID-19 DecisionsConsideration of Mortality Related to Unemployment, Social Isolation, and Depression

Tyler J. VanderWeele, PhD

doi : 10.1001/jama.2020.12187

JAMA. 2020;324(5):445-446.

This Viewpoint discusses how COVID-19–related policy decisions lead to trade-offs between medical, economic, social, and psychological outcomes, and emphasizes the need to account for deaths associated with unemployment and depression when estimating excess mortality.

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Behavioral Health Parity Efforts in the US

Andrew D. Carlo, MD, MPH; Brian S. Barnett, MD; Richard G. Frank, PhD

doi : 10.1001/jama.2020.3505

JAMA. 2020;324(5):447-448.

This Viewpoint discusses halting progress in legislative and policy attempts to make access to high-quality mental health and substance use disorders service equal to that for medical-surgical services and prospects for further regulation of insurance to achieve the goal.

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Assessing Quantitative Comparisons of Health and Social Care Between Countries

Michelle D. Carlson, MD; Brita Roy, MD, MPH, MHS; A. Stef Groenewoud, PhD

doi : 10.1001/jama.2020.3813

JAMA. 2020;324(5):449-450.

This Viewpoint discusses differences that complicate cross-country comparisons of health and social services and proposes a framework for assessing the appropriateness of those comparisons to help researchers improve their investigations and help readers critically appraise them.

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Eradicating Racial Injustice in Medicine—If Not Now, When?

Randy A. Vince Jr, MD

doi : 10.1001/jama.2020.12432

JAMA. 2020;324(5):451-452.

In this narrative medicine essay, a urology fellow offers 5 actions the medical community should take to eliminate racial injustice and health disparities in the United States.

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Editorial Evaluation and Peer Review During a PandemicHow Journals Maintain Standards

Howard Bauchner, MD; Phil B. Fontanarosa, MD, MBA; Robert M. Golub, MD

doi : 10.1001/jama.2020.11764

JAMA. 2020;324(5):453-454.

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A Randomized Trial of Convalescent Plasma for COVID-19—Potentially Hopeful Signals

Arturo Casadevall, MD, PhD; Michael J. Joyner, MD; Liise-Anne Pirofski, MD

doi : 10.1001/jama.2020.10218

JAMA. 2020;324(5):455-457.

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Mortality and MorbidityThe Measure of a Pandemic

Jody W. Zylke, MD; Howard Bauchner, MD

doi : 10.1001/jama.2020.11761

JAMA. 2020;324(5):458-459.

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Heart Failure With Reduced Ejection FractionA Review

Sean P. Murphy, MB, BCh, BAO; Nasrien E. Ibrahim, MD; James L. Januzzi Jr, MD

doi : 10.1001/jama.2020.10262

JAMA. 2020;324(5):488-504.

This narrative review summarizes the epidemiology, pathophysiology, diagnosis, management, and prognosis of heart failure with reduced ejection fraction.

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Tafamidis (Vyndaqel; Vyndamax) for Transthyretin Amyloid Cardiomyopathy

doi : 10.1001/jama.2020.0753

JAMA. 2020;324(5):505.

This Medical Letter review describes how tafamidis prevents transthyretin protein complexes from disocciating into amyloid fibrils, and its recent approval in 2 different formulations (Vyndaqel and Vyndamax) for treatment of adults with transthyretin-mediated amyloid cardiomyopathy (ATTR-CM).

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Taking a Closer Look at COVID-19, Health Inequities, and Racism

Jennifer Abbasi

doi : 10.1001/jama.2020.11672

JAMA. 2020;324(5):427-429

This Medical News article is an interview with Chicago public health legend and retired physician Linda Rae Murray, MD, MPH, an adjunct assistant professor at the University of Illinois at Chicago School of Public Health and a past president of the American Public Health Association.

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