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Quality of Literature Searches Published in Leading Neurosurgical Journals: A Review of Reviews
Tom J O’Donohoe, MBBS, MPH, Tahnee L Bridson, MBBS, BMedSci, Christopher G Shafik, BSc (Hons), MD, David Wynne, MBBS, Rana S Dhillon, MBBS, BA, MPhil, FRACS ...
doi : 10.1093/neuros/nyaa573
Volume 88, Issue 5, May 2021, Pages 891–899
There is mounting evidence that the search strategies upon which systematic reviews (SRs) are based frequently contain errors are incompletely reported or insensitive.
Neuropathology of Pituitary Adenomas and Sellar Lesions
Peter J Kobalka, MD, Kristin Huntoon, PhD, DO, Aline P Becker, MD, PhD
doi : 10.1093/neuros/nyaa548
Volume 88, Issue 5, May 2021, Pages 900–918
The pituitary gland is the site of numerous neoplastic and inflammatory processes. The overwhelmingly most frequent tumors arise from cells of the anterior lobe, the pituitary neuroendocrine tumors (PitNETs). Immunohistochemistry assay staining for pituitary hormones is the core tool for classifying PitNETs, resulting in the diagnosis of somatotroph PitNETs, lactotroph PitNETs, and so on.
Commentary: Neuropathology of Pituitary Adenomas and Sellar Lesions
Murat Gokden, MD
doi : 10.1093/neuros/nyaa569
Volume 88, Issue 5, May 2021, Pages E374–E376
Kudos to Kobalka et al1 for providing this comprehensive review on the pathology of pituitary adenomas (PA) and sellar lesions. Along with classical knowledge on PA and other lesions commonly seen in the sellar/suprasellar region, contemporary information such as the pituitary transcription factors and the concept of pituitary neuroendocrine tumors (PitNET) has been discussed.
New Philosophy, Clinical Pearls, and Methods for Intraoperative Cognition Mapping and Monitoring “à la carte” in Brain Tumor Patients
Hugues Duffau, MD, PhD
doi : 10.1093/neuros/nyaa363
Volume 88, Issue 5, May 2021, Pages 919–930
The purpose of surgery for brain tumors involving eloquent neural circuits is to maximize the extent of resection while preserving an optimal quality of life. To this end, especially in diffuse glioma, the goal is to remove the cerebral parenchyma invaded by the neoplasm up to the individual cortico-subcortical networks critical for brain functions. Intraoperative mapping combined with real-time cognitive monitoring throughout the resection in awake patient is thus highly recommended to resume a normal life.
Cerebrospinal Fluid-Venous Fistulas: A Systematic Review and Examination of Individual Patient Data
Nathan A Shlobin, BA, Vinil N Shah, MD, Cynthia T Chin, MD, William P Dillon, MD, Lee A Tan, MD
doi : 10.1093/neuros/nyaa558
Volume 88, Issue 5, May 2021, Pages 931–941
Spontaneous intracranial hypotension (SIH) is usually caused by a spinal cerebrospinal fluid (CSF) leak. CSF-venous fistula is an underdiagnosed cause of spinal CSF leak, as it is challenging to identify on myelography.
Commentary: Cerebrospinal Fluid-Venous Fistulas: A Systematic Review and Examination of Individual Patient Data
Berje H Shammassian, MD, MPH, Manish K Kasliwal, MD, MCh
doi : 10.1093/neuros/nyaa578
Volume 88, Issue 5, May 2021, Pages E377–E378
Spontaneous intracranial hypotension (SIH) commonly leads to orthostatic headaches, among other symptoms, including neck pain, nausea, tinnitus, and diplopia.1,2 Feared complications, although rare, can include subdural hematomas and cerebral venous sinus thrombosis.3 The correct diagnosis of this pathology is often delayed secondary to nonspecific symptoms, and management, including epidural blood patches, is not uniformly effective. SIH is most often secondary to spontaneous cerebrospinal fluid (CSF) leaks at the spinal level. Although the etiology may be secondary to dural weakening in the setting of connective tissue disorders, the idiopathic formation of meningeal diverticula is also a cause.4 The presence of a spinal longitudinal extradural CSF collection (SLEC) in patients with SIH has been an important radiographical finding portending the...
A Scoping Review of Burnout in Neurosurgery
Charles E Mackel, MD/JD, Emmalin B Nelton, BS, Renée M Reynolds, MD, W Christopher Fox, MD, Alejandro M Spiotta, MD ...
doi : 10.1093/neuros/nyaa564
Volume 88, Issue 5, May 2021, Pages 942–954
Burnout is a negative workplace syndrome of emotional exhaustion, cynicism, and perceived professional inefficacy that risks the patient-provider relationship, patient care, and physician well-being.
Commentary: A Scoping Review of Burnout in Neurosurgery
T Forcht Dagi, MD, DMedSc, DHC, FRCSEd
doi : 10.1093/neuros/nyaa575
Volume 88, Issue 5, May 2021, Pages E379–E380
The term “burnout” has entered the vernacular in many ways. The term was introduced to describe a specific phenomenon or syndrome associated with the altruistic professions such as medicine and nursing.
Asymptomatic Spinal Cord Compression: Is Surgery Necessary to Return to Play
Yunsoo Lee, MD, Stephen Selverian, MD, Wellington K Hsu, MD, Robert G Watkins, III, MD, Alexander R Vaccaro, MD, PhD, MBA ...
doi : 10.1093/neuros/nyaa554
Volume 88, Issue 5, May 2021, Pages 955–960
Advising athletes with asymptomatic cervical canal stenosis on their return to active play is a topic of considerable debate, with no definitive guidelines in place. Once cervical canal stenosis is identified, often through imaging following other injuries, it is difficult to predict the risk of future injury upon return to play in both contact and collision sports. Consequently, the decision can be a complicated one for the athlete, family, and physician alike.
Commentary: Asymptomatic Spinal Cord Compression: Is Surgery Necessary to Return to Play
Ehsan Dowlati, MD, Jean-Marc Voyadzis, MD
doi : 10.1093/neuros/nyab046
Volume 88, Issue 5, May 2021, Pages E381–E382
Guiding athletes with asymptomatic cervical stenosis on return to play has been a topic of considerable debate, specifically in light of the recent focus on athlete safety and risks posed by high-impact sports. In their review, “Asymptomatic Spinal Cord Compression: Is Surgery Necessary to Return to Play,” Lee et al1 present a review of this topic from the lens of radiographic and magnetic resonance imaging (MRI)-based criteria. Prior reviews attempting to provide recommendations demonstrate that the evidence is limited and of low quality.2,3 Furthermore, consensus from experts for this patient population has been difficult to achieve, with a wide range of opinions on management on this “gray” topic...
Social Determinants of Health and Neurosurgical Outcomes: Current State and Future Directions
Gregory Glauser, MBA, Donald K Detchou, BA, Ryan Dimentberg, BS, Ashwin G Ramayya, MD, PhD, Neil R Malhotra, MD
doi : 10.1093/neuros/nyab030
Volume 88, Issue 5, May 2021, Pages E383–E390
The relationship between social determinants of health (SDOH) and neurosurgical outcomes has become increasingly relevant. To date, results of prior work evaluating the impact of social determinants in neurosurgery have been mixed, and the need for robust data on this subject remains. The present review evaluates how gender, race, and socioeconomic status (SES) influence outcomes following various brain tumor resection procedures.
Intracerebral Hemorrhage Volume Reduction and Timing of Intervention Versus Functional Benefit and Survival in the MISTIE III and STICH Trials
Sean P Polster, MD, Juli?n Carri?n-Penagos, MD, Se?n B Lyne, BS, Barbara A Gregson, PhD, Ying Cao, MS ...
doi : 10.1093/neuros/nyaa572
Volume 88, Issue 5, May 2021, Pages 961–970
The extent of intracerebral hemorrhage (ICH) removal conferred survival and functional benefits in the minimally invasive surgery with thrombolysis in intracerebral hemorrhage evacuation (MISTIE) III trial. It is unclear whether this similarly impacts outcome with craniotomy (open surgery) or whether timing from ictus to intervention influences outcome with either procedure.
Commentary: Intracerebral Hemorrhage Volume Reduction and Timing of Intervention Versus Functional Benefit and Survival in the MISTIE III and STICH Trials
Tyler Scullen, MD, Mansour Mathkour, MD, Aaron S Dumont, MD, MBA
doi : 10.1093/neuros/nyab016
Volume 88, Issue 5, May 2021, Pages E391–E393
Spontaneous intraparenchymal hemorrhage (ICH) carries significant morbidity and mortality in contemporary medicine,1-5 with American Heart Association guidelines recommending reserving intervention for infratentorial and life-threatening supratentorial bleeds.6,7 Treatment is confounded by the unclear natural history of lobar ICH, which often occurs in comorbid populations and typically exhibits early volume expansion, threatening transtentorial herniation and intraventricular hemorrhage (IVH).
Commentary: Intracerebral Hemorrhage Volume Reduction and Timing of Intervention Versus Functional Benefit and Survival in the MISTIE III and STICH Trials
Michael W Robinson, MD, PhD, Charles J Prestigiacomo, MD, Laura B Ngwenya, MD, PhD
doi : 10.1093/neuros/nyab018
Volume 88, Issue 5, May 2021, Pages E394–E395
Despite numerous case series, randomized clinical trials, and meta-analyses, the benefit of surgical intervention for intracerebral hemorrhage (ICH) is still uncertain. The STICH-II trial compared initial medical management to early craniotomy and direct hematoma evacuation for lobar intracerebral hematomas.
Cognitive Functioning and Health-Related Quality of Life of Long-Term Survivors With Brain Metastases Up to 21 Months After Gamma Knife Radiosurgery
Eline Verhaak, PhD, Wietske C M Schimmel, MSc, Karin Gehring, PhD, Patrick E J Hanssens, MD, Margriet M Sitskoorn, PhD
doi : 10.1093/neuros/nyaa586
Volume 88, Issue 5, May 2021, Pages E396–E405
Survival rates have improved in the past years for patients with brain metastases (BMs).
Prognostic Factors Associated With Surviving Less Than 3 Months vs Greater Than 3 Years Specific to Spine Stereotactic Body Radiotherapy and Late Adverse Events
K Liang Zeng, MD, Arjun Sahgal, MD, Chia-Lin Tseng, MDCM, Sten Myrehaug, MD, Hany Soliman, MD ...
doi : 10.1093/neuros/nyaa583
Volume 88, Issue 5, May 2021, Pages 971–979
Patient selection is critical for spine stereotactic body radiotherapy (SBRT) given potential for serious adverse effects and the associated costs.
Commentary: Prognostic Factors Associated With Surviving Less Than 3 Months vs Greater Than 3 Years Specific to Spine Stereotactic Body Radiotherapy and Late Adverse Events
Boryana M Eastman, MD, PhD, Rajiv Saigal, MD, PhD, Christoph P Hofstetter, MD, PhD, Matthew Foote, MB, BS, FRANZCR, Nina A Mayr, MD ...
doi : 10.1093/neuros/nyab029
Volume 88, Issue 5, May 2021, Pages E406–E407
Bone metastasis is a significant cause of morbidity, affecting over 8% of all patients diagnosed with solid malignancies in the USA at 10 yr. Treatment of vertebral metastasis is an active area of research, given their high incidence, likelihood to become symptomatic, and propensity to lead to neurological compromise. Zeng et al1 identified a practical set of easily evaluated predictive features that can aid physicians in the decision making between stereotactic body radiotherapy (SBRT) and simpler, easier to tolerate and less costly conventional palliative radiotherapy. With the increasing ease of its planning and delivery, SBRT has been more widely utilized representing 5.8% of spine radiation therapy cases in 2013 compared to 1.4% in 2004. As reflection of the emerging evidence and treatment...
Stereotactic Radiosurgery for Atypical (World Health Organization II) and Anaplastic (World Health Organization III) Meningiomas: Results From a Multicenter, International Cohort Study
Matthew J Shepard, MD, Zhiyuan Xu, MD, Kathryn Kearns, BS, Chelsea Li, BS, Ajay Chatrath, BS ...
doi : 10.1093/neuros/nyaa553
Volume 88, Issue 5, May 2021, Pages 980–988
Atypical and anaplastic meningiomas have reduced progression-free/overall survival (PFS/OS) compared to benign meningiomas. Stereotactic radiosurgery (SRS) for atypical meningiomas (AMs) and anaplastic meningiomas (malignant meningiomas, MMs) has not been adequately described.
Commentary: Stereotactic Radiosurgery for Atypical (World Health Organization II) and Anaplastic (World Health Organization III) Meningiomas: Results From a Multicenter, International Cohort Study
Ching-Jen Chen, MD, Dale Ding, MD
doi : 10.1093/neuros/nyaa594
Volume 88, Issue 5, May 2021, Pages E408–E409
It is often challenging to safely achieve gross total resection (GTR) for atypical (World Health Organization [WHO] grade II) or anaplastic (WHO grade III) intracranial meningiomas, and incompletely resected grade II-III meningiomas have a high rate of recurrence and associated mortality.1,2 Radiation therapy (RT) is the mainstay postoperative treatment for these tumors following upfront surgical resection, especially in patients with malignant meningiomas or incompletely resected atypical meningiomas.3 Fractionated RT with a total dose of approximately 60 Gy has been the traditional treatment of choice for grade II-III meningiomas.4,5 Increasingly popular radiation delivery techniques, such as stereotactic radiosurgery (SRS), hypofractionated RT, and heavy...
Improvement in Quality of Life Following Surgical Resection of Benign Intradural Extramedullary Tumors: A Prospective Evaluation of Patient-Reported Outcomes
William C Newman, MD, John Berry-Candelario, MD, Jemma Villavieja, BS, Anne S Reiner, MPH, Mark H Bilsky, MD ...
doi : 10.1093/neuros/nyaa561
Volume 88, Issue 5, May 2021, Pages 989–995
Historically, symptomatic, benign intradural extramedullary (IDEM) spine tumors have been managed with surgical resection. However, minimal robust data regarding patient-reported outcomes (PROs) following treatment of symptomatic lesions exists. Moreover, there are increasing reports of radiosurgical management of these lesions without robust health-related quality of life data.
Spetzler-Martin Grade III Arteriovenous Malformations: A Multicenter Propensity-Adjusted Analysis of the Effects of Preoperative Embolization
Joshua S Catapano, MD, Fabio A Frisoli, MD, Candice L Nguyen, BS, D Andrew Wilkinson, MD, Neil Majmundar, MD ...
doi : 10.1093/neuros/nyaa551
Volume 88, Issue 5, May 2021, Pages 996–1002
Spetzler-Martin (SM) grade III arteriovenous malformations (AVMs) are at the boundary of safe operability, and preoperative embolization may reduce surgical risks.
Machine Learning-Driven Metabolomic Evaluation of Cerebrospinal Fluid: Insights Into Poor Outcomes After Aneurysmal Subarachnoid Hemorrhage
Matthew Koch, MD, Animesh Acharjee, PhD, Zsuzsanna Ament, PhD, Riana Schleicher, BS, Matthew Bevers, MD, PhD ...
doi : 10.1093/neuros/nyaa557
Volume 88, Issue 5, May 2021, Pages 1003–1011
Aneurysmal subarachnoid hemorrhage (aSAH) is associated with a high mortality and poor neurologic outcomes. The biologic underpinnings of the morbidity and mortality associated with aSAH remain poorly understood.
Commentary: Machine Learning-Driven Metabolomic Evaluation of Cerebrospinal Fluid: Insights Into Poor Outcomes After Aneurysmal Subarachnoid Hemorrhage
Mark N Pernik, BA, Jeffrey I Traylor, MD, Tarek Y El Ahmadieh, MD, Carlos A Bagley, MD, Salah G Aoun, MD
doi : 10.1093/neuros/nyaa595
Volume 88, Issue 5, May 2021, Pages E410–E411
Aneurysmal subarachnoid hemorrhage (SAH) is a life-threatening event that can be neurologically devastating, even when treated appropriately. In the manuscript titled “Machine Learning-Driven Metabolomic Evaluation of Cerebrospinal Fluid: Insights Into Poor Outcomes After Aneurysmal Subarachnoid Hemorrhage,”1 the authors used elastic net machine learning, an artificial intelligence (AI) technique, to identify potential cerebrospinal fluid (CSF) biomarkers associated with outcomes in aneurysmal SAH patients.
Commentary: Machine Learning-Driven Metabolomic Evaluation of Cerebrospinal Fluid: Insights Into Poor Outcomes After Aneurysmal Subarachnoid Hemorrhage
Christoph Wipplinger, MD, Christoph J Griessenauer, MD
doi : 10.1093/neuros/nyab033
Volume 88, Issue 5, May 2021, Pages E412–E414
Aneurysmal subarachnoid hemorrhage (aSAH) is associated with a high morbidity and mortality. Despite successful and timely initial treatment, patients may experience secondary brain injury. In most cases, this is caused by delayed cerebral ischemia (DCI), frequently attributed to vasospasm.1 Although several risk factors associated with DCI are known, the underlying mechanism is not fully understood.2 This is especially true for DCI in the absence of angiographic vasospasm.
Retrobulbar Hemangioblastomas in von Hippel-Lindau Disease: Clinical Course and Management
Reinier Alvarez, BS, Panagiotis Mastorakos, MD, PhD, Elizabeth Hogan, MD, Gretchen Scott, RN, Russell R Lonser, MD ...
doi : 10.1093/neuros/nyaa565
Volume 88, Issue 5, May 2021, Pages 1012–1020
Retrobulbar hemangioblastomas involving the optic apparatus in patients with von Hippel-Lindau disease (VHL) are rare, with only 25 reported cases in the literature.
Postoperative Stereotactic Body Radiotherapy for Spinal Metastasis and Predictors of Local Control
Dukagjin M Blakaj, MD, PhD, Joshua D Palmer, MD, Khaled Dibs, MD, Alexander Olausson, MD, Eric C Bourekas, MD, MBA ...
doi : 10.1093/neuros/nyaa587
Volume 88, Issue 5, May 2021, Pages 1021–1027
Spine surgery is indicated for select patients with mechanical instability, pain, and/or malignant epidural spinal cord compression, with or without neurological compromise. Stereotactic body radiotherapy (SBRT) is an option for durable local control (LC) for metastatic spine disease.
Safety, Efficacy, and Durability of Stent Plus Balloon-Assisted Coiling for the Treatment of Wide-Necked Intracranial Bifurcation Aneurysms
Kubilay Aydin, MD, Paul Stracke, MD, Mynzhylky Berdikhojayev, MD, Mehmet Barburoglu, MD, Pascal J Mosimann, MD ...
doi : 10.1093/neuros/nyaa590
Volume 88, Issue 5, May 2021, Pages 1028–1037
Wide-necked bifurcation aneurysms remain a challenge for endovascular surgeons. Dual-stent-assisted coiling techniques have been defined to treat bifurcation aneurysms with a complex neck morphology. However, there are still concerns about the safety of dual-stenting procedures. Stent plus balloon-assisted coiling is a recently described endovascular technique that enables the coiling of wide-necked complex bifurcation aneurysms by implanting only a single stent.
Commentary: Safety, Efficacy, and Durability of Stent Plus Balloon-Assisted Coiling for the Treatment of Wide-Necked Intracranial Bifurcation Aneurysms
Jae Eun Lee, BA, Peter Kan, MD, MPH, FRCSC
doi : 10.1093/neuros/nyab006
Volume 88, Issue 5, May 2021, Pages E415–E416
Wide-necked bifurcation aneurysms (WNBAs) remain the Achilles heel of endovascular therapy. Traditional endovascular options include balloon- or stent-assisted coiling. A core lab adjudicated study by De Leacy et al1 demonstrated a modest RR1 occlusion rate of 31% at a mean follow-up of 49 wk after stent-assisted coiling of middle cerebral artery or basilar apex WNBA with a retreatment rate of 9%. Recently, parent vessel flow diversion, intrasaccular flow disruption, and neck-bridging devices such as PulseRider (Pulsar Vascular) offer additional options in the treatment of this subset of intracranial aneurysms with similar results.2-4 Advance dual-stenting techniques, such as X- or Y-stenting, have certainly remained in the armamentarium and were often the preferred endovascular treatment for the more complex WNBAs. In the recent...
Commentary: Safety, Efficacy, and Durability of Stent Plus Balloon-Assisted Coiling for the Treatment of Wide-Necked Intracranial Bifurcation Aneurysms
MirHojjat Khorasanizadeh, MD, Christopher S Ogilvy, MD
doi : 10.1093/neuros/nyab008
Volume 88, Issue 5, May 2021, Pages E417–E419
With all the progress made in endovascular neurosurgery in recent years, management of bifurcation aneurysms (BAs) still remains a challenging task. These aneurysms usually have wide necks, which incite herniation of the coil back into the parent vessel, are more likely to have complex morphologies, and incorporate neighboring bifurcation branches; all of which impair complete occlusion of the aneurysm and increase the risk of unwanted occlusion of parent or neighboring vessels.1 Therefore, BA patients are more commonly considered poor candidates for endovascular intervention, and surgical clipping is still widely used for the treatment of this subgroup of aneurysms.
Electrocorticography During Deep Brain Stimulation Surgery: Safety Experience From 4 Centers Within the National Institute of Neurological Disorders and Stroke Research Opportunities in Human Consortium
Nathaniel D Sisterson, MD, April A Carlson, MD, Ueli Rutishauser, PhD, Adam N Mamelak, MD, Mitchell Flagg, BS ...
doi : 10.1093/neuros/nyaa592
Volume 88, Issue 5, May 2021, Pages E420–E426
Intraoperative research during deep brain stimulation (DBS) surgery has enabled major advances in understanding movement disorders pathophysiology and potential mechanisms for therapeutic benefit. In particular, over the last decade, recording electrocorticography (ECoG) from the cortical surface, simultaneously with subcortical recordings, has become an important research tool for assessing basal ganglia-thalamocortical circuit physiology.
Prediction Models in Aneurysmal Subarachnoid Hemorrhage: Forecasting Clinical Outcome With Artificial Intelligence
Guido de Jong, MSc, René Aquarius, PhD, Barof Sanaan, MSc, Ronald H M A Bartels, MD, PhD, J André Grotenhuis, MD, PhD ...
doi : 10.1093/neuros/nyaa581
Volume 88, Issue 5, May 2021, Pages E427–E434
Predicting outcome after aneurysmal subarachnoid hemorrhage (aSAH) is known to be challenging and complex. Machine learning approaches, of which feedforward artificial neural networks (ffANNs) are the most widely used, could contribute to the patient-specific outcome prediction.
Adjuvant Radiotherapy Versus Watchful Waiting for World Health Organization Grade II Atypical Meningioma: A Single-Institution Experience
David P Bray, MD, Joseph W Quillin, MD, Robert H Press, MD, Yilin Yang, BS, Zhengjia Chen, PhD ...
doi : 10.1093/neuros/nyaa580
Volume 88, Issue 5, May 2021, Pages E435–E442
Atypical meningiomas (AMs) are meningiomas that have a higher rate of recurrence than grade I meningioma. Due to the higher risk of recurrence, adjuvant radiotherapy (RT) after resection of AM has been employed. At our institution, some neurosurgeons employ adjuvant RT on all primarily resected AMs, while others employ watchful waiting with serial imaging.
Commentary: Adjuvant Radiotherapy Versus Watchful Waiting for World Health Organization Grade II Atypical Meningioma: A Single-Institution Experience
Michael R Chicoine, MD, Albert H Kim, MD, PhD
doi : 10.1093/neuros/nyab048
Volume 88, Issue 5, May 2021, Pages E443–E444
We read with interest “Adjuvant Radiotherapy vs Watchful Waiting for World Health Organization Grade II Atypical Meningioma: A Single-Institution Experience.”1 This was a retrospective investigation of a cohort of 162 patients with atypical meningiomas. Based on clinicians' preference, 108 of those patients underwent adjuvant postoperative radiation therapy (RT) and 54 did not. For those patients who underwent RT, all patients (except for 3 that received stereotactic RT) received fractionated external beam RT with doses ranging from 18 to 60 Gy. Multivariate analysis was used to assess the impact of radiation. The authors conclude that radiation is associated with a lower risk of recurrence. The mean time to recurrence in patients who received radiation was 43.7 mo, which is modestly longer than the...
Effect of Incisional Negative Pressure Wound Therapy vs Standard Wound Dressing on the Development of Surgical Site Infection after Spinal Surgery: A Prospective Observational Study
Kyle B Mueller, MD, Matthew D’Antuono, BS, Nirali Patel, MD, Gnel Pivazyan, MD, Edward F Aulisi, MD ...
doi : 10.1093/neuros/nyab040
Volume 88, Issue 5, May 2021, Pages E445–E451
Use of a closed-incisional negative pressure therapy (ci-NPT) dressing is an emerging strategy to reduce surgical site infections (SSIs) in spine surgery that lacks robust data.
Developing a Professionalism and Harassment Policy for Organized Neurosurgery
Ellen L Air, MD, PhD, Katie O Orrico, JD, Deborah L Benzil, MD, Alan M Scarrow, MD, JD, James R Bean, MD ...
doi : 10.1093/neuros/nyab051
Volume 88, Issue 5, May 2021, Pages 1038–1039
Annual conferences, educational courses, and other meetings draw a diverse community of individuals, yet also create a unique environment without the traditional guard rails. Unlike events held at one's home institution, clear rules and jurisdiction have not been universally established. To promote the open exchange of ideas, as well as an environment conducive to professional growth of all participants, the leading neurosurgical professional organizations joined forces to delineate the expectations for anyone who participates in sponsored events.
Letter: Virtual Reality in Neurosurgical Education: Modernizing the Medical Classroom
Rohitha Baskar, BS, Vamsi Reddy, BS, Marianne I Tissot, BA, Donald K Detchou, BA, Zoe E Teton, MD ...
doi : 10.1093/neuros/nyab004
Volume 88, Issue 5, May 2021, Page E452
Letter: Tirofiban Protocol Protects Against Delayed Cerebral Ischemia: A Case-Series Study
Brayan S Aristizabal-Carmona, MS, Ivan D Lozada-Martinez, MS, Daniela M Torres-Llin?s, MS, Luis R Moscote-Salazar, MD, Ezequiel Garc?a-Ballestas, MD ...
doi : 10.1093/neuros/nyab002
Volume 88, Issue 5, May 2021, Pages E453–E454
In Reply: Tirofiban Protocol Protects Against Delayed Cerebral Ischemia: A Case-Series Study
Anthony Piscopo, BS, Mario Zanaty, MD, David Hasan, MD
doi : 10.1093/neuros/nyab007
Volume 88, Issue 5, May 2021, Page E455
Letter: A Systematic Review of Deep Brain Stimulation Targets for Obsessive-Compulsive Disorder
Giulio Bonomo, MD, Ignazio G Vetrano, MD
doi : 10.1093/neuros/nyab005
Volume 88, Issue 5, May 2021, Pages E456–E457
In Reply: A Systematic Review of Deep Brain Stimulation Targets for Obsessive-Compulsive Disorder
Amir Hadanny, MD, Julie G Pilitsis, MD, PhD
doi : 10.1093/neuros/nyab010
Volume 88, Issue 5, May 2021, Page E458
Letter: Commentary: Maximilian Sternberg (1863–1934): The Man Behind Sternberg's Canal and his Contribution to the Modern-Day Skull Base Anatomy and Neuroscience—Historical Vignette
Connor G Koch, BS, Jessica W Grayson, MD, Bradford A Woodworth, MD
doi : 10.1093/neuros/nyab014
Volume 88, Issue 5, May 2021, Pages E459–E460
In Reply: Commentary: Maximilian Sternberg (1863–1934): The Man Behind Sternberg's Canal and his Contribution to the Modern-Day Skull Base Anatomy and Neuroscience—Historical Vignette
Jai Deep Thakur, MD, Amey R Savardekar, MCh, Bharath Raju, MCh, Anil Nanda, MD, MPH
doi : 10.1093/neuros/nyab058
Volume 88, Issue 5, May 2021, Page E461
Letter: Cranioplasty Reverses Dysfunction of the Solutes Distribution in the Brain Parenchyma After Decompressive Craniectomy
Nathan Beucler, MD, Aurore Sellier, MD, Arnaud Dagain, MD, MS
doi : 10.1093/neuros/nyab003
Volume 88, Issue 5, May 2021, Pages E462–E463
In Reply: Cranioplasty Reverses Dysfunction of the Solutes Distribution in the Brain Parenchyma After Decompressive Craniectomy
Alin Borha, MD, MSc, Thomas Gaberel, MD, PhD
doi : 10.1093/neuros/nyab012
Volume 88, Issue 5, May 2021, Page E464
Letter: Training of Microsurgical Aneurysm Clipping in the Endovascular Era: Towards Structured Fellowship Programs in Europe
Roel Haeren, MD, PhD, Christoph Schwartz, MD, MHBA, Jarno Satop??, MD, PhD, Martin Lehecka, MD, PhD, Mika Niemel?, MD, PhD
doi : 10.1093/neuros/nyab011
Volume 88, Issue 5, May 2021, Pages E465–E466
Letter: Video Documentation of Operative Note in Neurosurgery-Old Wine in a New Bottle!
Nadia Liber Salloum, BMedSci (Hons), MBChB (Hons), Phillip Correia Copley, BSc (Hons), BMBS, MRCS (Ed), Chandrasekaran Kaliaperumal, DipMedEd, FEBNS, FRCSI, FRCSEd (Neuro.Surg)
doi : 10.1093/neuros/nyab015
Volume 88, Issue 5, May 2021, Pages E467–E468
Letter: A Call to Action: Increasing Black Representation in Neurological Surgery
Donald K Detchou, BA, Alvin Onyewuenyi, MPH, Vamsi Reddy, BS, Andre Boyke, MS, Nnenna Mbabuike, MD ...
doi : 10.1093/neuros/nyab057
Volume 88, Issue 5, May 2021, Pages E469–E473
Letter: Early Prediction of Malignant Cerebellar Edema in Posterior Circulation Stroke Using Quantitative Lesion Water Uptake
Juan Maiguel-Lapeira, MS, Ivan Lozada-Mart?nez, MS, Daniela Torres-Llin?s, MS, Luis Moscote-Salazar, MD, Yelson Pic?n-Jaimes, MD ...
doi : 10.1093/neuros/nyab031
Volume 88, Issue 5, May 2021, Pages E474–E475
In Reply: Early Prediction of Malignant Cerebellar Edema in Posterior Circulation Stroke Using Quantitative Lesion Water Uptake
Gabriel Broocks, MD, Jens Fiehler, MD, Uta Hanning, MD, MHBA
doi : 10.1093/neuros/nyab032
Volume 88, Issue 5, May 2021, Pages E476–E477
Letter: Case Series: Unilateral Amygdala Ablation Ameliorates Post-Traumatic Stress Disorder Symptoms and Biomarkers
Rachyl M Shanker, MD, Elhaum G Rezaii, MPH, Miri Kim, MD, PhD, Douglas E Anderson, MD
doi : 10.1093/neuros/nyab025
Volume 88, Issue 5, May 2021, Pages E478–E479
In Reply: Case Series: Unilateral Amygdala Ablation Ameliorates Post-Traumatic Stress Disorder Symptoms and Biomarkers
Sanne J H van Rooij, PhD, Kelly R Bijanki, PhD, Jon T Willie, MD, PhD
doi : 10.1093/neuros/nyab028
Volume 88, Issue 5, May 2021, Pages E480–E481
Letter: Commentary: Costs and Their Predictors in Transsphenoidal Pituitary Surgery
Anthony O Asemota, MD, MPH, Masaru Ishii, MD, PhD, Henry Brem, MD, Gary L Gallia, MD, PhD
doi : 10.1093/neuros/nyab027
Volume 88, Issue 5, May 2021, Pages E482–E483
Letter: Tranexamic Acid and Severe Traumatic Brain Injury: The Futile Search for Causality?
Victor Volovici, MD, PhD, Iain K Haitsma, MD
doi : 10.1093/neuros/nyab034
Volume 88, Issue 5, May 2021, Pages E484–E485
Letter: Protective Effects of Obstructive Sleep Apnea on Outcomes After Subarachnoid Hemorrhage: A Nationwide Analysis
Simranjeet Singh, MBBS, Satish Verma, MCh
doi : 10.1093/neuros/nyab047
Volume 88, Issue 5, May 2021, Pages E486–E487
Letter: Presurgical Identification of Patients With Glioblastoma at Risk for Cognitive Impairment at 3-Month Follow-up
Grazia Menna, MD, Valerio Maria Caccavella, MD, Alessandro Olivi, MD, Giuseppe Maria Della Pepa, MD
doi : 10.1093/neuros/nyab045
Volume 88, Issue 5, May 2021, Page E488
Corrigendum to: 2020 ACCEPTED ABSTRACTS, Clinical Neurosurgery, Volume 67, Issue Supplement_1, December 2020, https://doi.org/10.1093/neuros/nyaa447
doi : 10.1093/neuros/nyab037
Volume 88, Issue 5, May 2021, Pages 1040–1042
Corrigendum to: “The Role of Prophylactic Intraventricular Antibiotics in Reducing the Incidence of Infection and Revision Surgery in Pediatric Patients Undergoing Shunt Placement” by Nikita Lakomkin, MD, Constantinos G Hadjipanayis, MD, PhD. Neurosurgery, Volume 88, Issue 2, February 2021, Pages 301-305, https://doi.org/10.1093/neuros/nyaa413
doi : 10.1093/neuros/nyab038
Volume 88, Issue 5, May 2021, Page 1042
