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A Neurosurgeon's Guide to Cognitive Dysfunction in Adult Glioma
Ramin A Morshed, MD, Jacob S Young, MD, Arlena A Kroliczek, PsyD, Mitchel S Berger, MD, David Brang, PhD, Shawn L Hervey-Jumper, MD
doi : 10.1093/neuros/nyaa400
Neurosurgery, Volume 89, Issue 1, July 2021, Pages 1–10
Cognitive decline is common among patients with low- and high-grade glioma and can significantly impact quality of life. Although cognitive outcomes have been studied after therapeutic interventions such as surgery and radiation, it is important to understand the impact of the disease process itself prior to any interventions. Neurocognitive domains of interest in this disease context include intellectual function and premorbid ability, executive function, learning and memory, attention, language function, processing speed, visuospatial function, motor function, and emotional function. Here, we review oncologic factors associated with more neurocognitive impairment, key neurocognitive tasks relevant to glioma patient assessment, as well as the relevance of the human neural connectome in understanding cognitive dysfunction in glioma patients. A contextual understanding of glioma-functional network disruption and its impact on cognition is critical in the surgical management of eloquent area tumors.
Commentary: A Neurosurgeon's Guide to Cognitive Dysfunction in Adult Glioma
Ethan S Srinivasan, BS, Vadim Tsvankin, MD, Peter E Fecci, MD, PhD
doi : 10.1093/neuros/nyaa408
Neurosurgery, Volume 89, Issue 1, July 2021, Pages E1–E2
Meningioma: A Pathology Perspective
Angus Toland, MD, Kristin Huntoon, PhD, DO, Sonika M Dahiya, MBBS, MD
doi : 10.1093/neuros/nyab001
Neurosurgery, Volume 89, Issue 1, July 2021, Pages 11–21
Meningiomas are dural-based neoplasms that account for ?37% of all intracranial tumors in the adult population. They can occur anywhere within the central nervous system and have a predilection for females. The World Health Organization classifies meningiomas into 3 grades based on increased risk of recurrence and associated mortality in grade III tumors. Although most tumors are categorized as low-grade, up to ?15%-20% demonstrate more aggressive behavior. With the long-recognized association with neurofibromatosis type 2 gene mutation, putative driver mutations can be attributed to ?80% of tumors.
A Quantitative Systematic Review of Clinical Outcome Measure Use in Peripheral Nerve Injury of the Upper Limb
Ralph N A Murphy, BSc, MBBS, MRCS, Heba Elsayed, MBBCh, MS, Sahiba Singh, BSc, MBBS, MRCS, Jo Dumville, BSc, MSC, PhD, Jason K F Wong, MBChB, FHEA, PhD, FRCS(Plast), Adam J Reid, MBChB, FRCS(Plast), PhD
doi : 10.1093/neuros/nyab060
Neurosurgery, Volume 89, Issue 1, July 2021, Pages 22–30
Peripheral nerve injury (PNI) is common, leading to reduced function, pain, and psychological impact. Treatment has not progressed partly due to inability to compare outcomes between centers managing PNI. Numerous outcome measures exist but there is no consensus on which outcome measures to use nor when.
Machine Learning for the Prediction of Molecular Markers in Glioma on Magnetic Resonance Imaging: A Systematic Review and Meta-Analysis
Anne Jian, MD, Kevin Jang, MBBS, Maurizio Manuguerra, PhD, Sidong Liu, PhD, John Magnussen, MBBS, PhD, FRANZCR, Antonio Di Ieva, MD, PhD, FRACS
doi : 10.1093/neuros/nyab103
Neurosurgery, Volume 89, Issue 1, July 2021, Pages 31–44
Molecular characterization of glioma has implications for prognosis, treatment planning, and prediction of treatment response. Current histopathology is limited by intratumoral heterogeneity and variability in detection methods. Advances in computational techniques have led to interest in mining quantitative imaging features to noninvasively detect genetic mutations.
Origin and Use of Hydrogen Peroxide in Neurosurgery
David Bailey, BS, Elias B Rizk, MD
doi : 10.1093/neuros/nyab107
Neurosurgery, Volume 89, Issue 1, July 2021, Pages E3–E7,
Hydrogen peroxide (H2O2) is a chemical with a wide range of applications. This includes its use in the medical field, in which its use has been ubiquitous but is most useful as an antiseptic and in achieving hemostasis. Neurosurgeons have been using H2O2 for well over a century, primarily for its hemostatic and antiseptic effects. This is in spite of the fact that the actual effectiveness of H2O2 as an antiseptic is questionable, and its use, in general, may be more dangerous than it appears. We review the application of H2O2 in medicine generally and, more specifically, in neurosurgery.
Thalamic Deep Brain Stimulation for Spasmodic Dysphonia: A Phase I Prospective Randomized Double-Blind Crossover Trial
Christopher R Honey, MD, DPhil, FRCSC, Marie T Krüger, MD, Tim?teo Almeida, MD, PhD, Linda A Rammage, PhD, Mandeep S Tamber, MD, PhD, FRCSC, Murray D Morrison, MD, FRCSC, Anujan Poologaindran, MSc, Amanda Hu, MD, FRCSC
doi : 10.1093/neuros/nyab095
Neurosurgery, Volume 89, Issue 1, July 2021, Pages 45–52
Adductor spasmodic dysphonia (SD) is a dystonia of the vocal folds causing difficulty with speech. The current standard of care is repeated botulinum toxin injections to weaken the adductor muscles. We sought to ameliorate the underlying neurological cause of SD with a novel therapy—deep brain stimulation (DBS).
Neurosurgery Resident Interviews: The Prevalence and Impact of Inappropriate and Potentially Illegal Questions
Natalie Limoges, DO, Scott L Zuckerman, MD, MPH, Lola B Chambless, MD, Deborah L Benzil, MD, Aurora Cruz, MD, MBA, Jonathan H Borden, BS, Susan Durham, MD, MS
doi : 10.1093/neuros/nyab059
Neurosurgery, Volume 89, Issue 1, July 2021, Pages 53–59
The impact of workplace discrimination has gained recognition. Nearly two-thirds of all medical residency applicants reported being asked inappropriate or potentially illegal interview questions. The use of such questions during neurosurgery residency interviews has not yet been studied.
Commentary: Neurosurgery Resident Interviews: The Prevalence and Impact of Inappropriate and Potentially Illegal Questions
Tyler Scullen, MD, Mansour Mathkour, MD, Monica Noya Santana, MD, Aaron S Dumont, MD, MBA
doi : 10.1093/neuros/nyab117
Neurosurgery, Volume 89, Issue 1, July 2021, Pages E8–E10
no abstract
Rotational Angiography-Based Gamma Knife Radiosurgery for Brain Arteriovenous Malformations: Preliminary Therapeutic Outcomes of the Novel Method
Yuki Shinya, MD, Hirotaka Hasegawa, MD, PhD, Masahiro Shin, MD, PhD, Mariko Kawashima, MD, Takehiro Sugiyama, MD, MSHS, PhD, Osamu Ishikawa, MD, PhD, Satoshi Koizumi, MD, Yuichi Suzuki, PhD, Hirofumi Nakatomi, MD, PhD, Nobuhito Saito, MD, PhD
doi : 10.1093/neuros/nyab066
Neurosurgery, Volume 89, Issue 1, July 2021, Pages 60–69
High-definition vascular imaging is desirable for treatment planning in Gamma Knife radiosurgery (GKRS; Elekta AB) for brain arteriovenous malformations (BAVMs). Currently, rotational angiography (RA) provides the clearest 3-dimensional visualization of niduses with high spatial resolution; however, its efficacy for GKRS has not been clarified. At our institution, RA has been integrated into GKRS (RA-GKRS) for better treatment planning and outcomes since 2015.
Reducing Superfluous Opioid Prescribing Practices After Brain Surgery: It Is Time to Talk About Drugs
Karam Asmaro, MD, MS, Hassan A Fadel, MD, Sameah A Haider, MD, MBA, Jacob Pawloski, MD, Edvin Telemi, MD, Tarek R Mansour, MD, Ankush Chandra, MD, MS, Michael Bazydlo, MS, Adam M Robin, MD, Ian Y Lee, MD, Ellen L Air, MD, PhD, Jack P Rock, MD, Steven N Kalkanis, MD, Jason M Schwalb, MD
doi : 10.1093/neuros/nyab061
Neurosurgery, Volume 89, Issue 1, July 2021, Pages 70–76
Opioids are prescribed routinely after cranial surgery despite a paucity of evidence regarding the optimal quantity needed. Overprescribing may adversely contribute to opioid abuse, chronic use, and diversion.
Are Guidelines Important? Results of a Prospective Quality Improvement Lumbar Fusion Project
James Harrop, MD, MSHQS, Alexandra Emes, BS, Ameet Chitale, MD, Chengyuan Wu, MD, Fadi Al Saiegh, MD, Geoffrey Stricsek, MD, Glenn A Gonzalez, MD, Jack Jallo, MD, PhD, Josh Heller, MD, MBA, Kevin Hines, MD, Lucas Philipp, MD, Sara Thalheimer, BA, Srinivas K Prasad, MD, MS, Thiago S Montenegro, MD, Umma Fatema, BS, Ashwini Sharan, MD, MSHQS
doi : 10.1093/neuros/nyab062
Neurosurgery, Volume 89, Issue 1, July 2021, Pages 77–84
United States (U.S.) healthcare is a volume-based inefficient delivery system. Value requires the consideration of quality, which is lacking in most healthcare disciplines.
Postoperative Admission of Adult Craniotomy Patients to the Neuroscience Ward Reduces Length of Stay and Cost
Matthew Z Sun, MD, Diana Babayan, MPH, Jia-Shu Chen, BS, Maxwell M Wang, BS, Priyanka K Naik, BS, Kara Reitz, BS, Jingyi Jessica Li, PhD, Nader Pouratian, MD, PhD, Won Kim, MD
doi : 10.1093/neuros/nyab089
Neurosurgery, Volume 89, Issue 1, July 2021, Pages 85–93
The neurointensive care unit (NICU) has traditionally been the default recovery unit after elective craniotomies.
Commentary: Postoperative Admission of Adult Craniotomy Patients to the Neuroscience Ward Reduces Length of Stay and Cost
Thomas K Mattingly, MD, MSc
doi : 10.1093/neuros/nyab092
Neurosurgery, Volume 89, Issue 1, July 2021, Pages E11–E12
Nonunion Rates After Anterior Cervical Discectomy and Fusion: Comparison of Polyetheretherketone vs Structural Allograft Implants
Won Hyung A Ryu, MD, MSc, MTM, Dominick Richards, BA, Mena G Kerolus, MD, Adewale A Bakare, MD, Ryan Khanna, MD, Victoria D Vuong, MD, Harel Deutsch, MD, Ricardo Fontes, MD, PhD, John E O’Toole, MD, MS, Vincent C Traynelis, MD, Richard G Fessler, MD, PhD
doi : 10.1093/neuros/nyab079
Neurosurgery, Volume 89, Issue 1, July 2021, Pages 94–101
Although advances in implant materials, such as polyetheretherketone (PEEK), have been developed aimed to improve outcome after anterior cervical discectomy and fusion (ACDF), it is essential to confirm whether these changes translate into clinically important sustained benefits.
Commentary: Nonunion Rates After Anterior Cervical Discectomy and Fusion: Comparison of Polyetheretherketone vs Structural Allograft Implants
Nikhil K Murthy, MD, MS, Nader S Dahdaleh, MD
doi : 10.1093/neuros/nyab102
Neurosurgery, Volume 89, Issue 1, July 2021, Pages E13–E14
Commentary: Nonunion Rates After Anterior Cervical Discectomy and Fusion: Comparison of Polyetheretherketone vs Structural Allograft Implants
Praveen V Mummaneni, MD, MBA, Gregory A Kuzmik, MD
doi : 10.1093/neuros/nyab135
Neurosurgery, Volume 89, Issue 1, July 2021, Page E15
Neuroform Atlas Stent for Treatment of Middle Cerebral Artery Aneurysms: 1-Year Outcomes From Neuroform Atlas Stent Pivotal Trial
Ricardo A Hanel, MD, PhD, Nam Yoon, MD, Eric Sauvageau, MD, Amin Aghaebrahim, MD, Eugene Lin, MD, Ashutosh P Jadhav, MD, PhD, Tudor G Jovin, MD, Ahmad Khaldi, MD, Rishi G Gupta, MD, Andrew Johnson, MD, Donald Frei, MD, David Loy, MD, Adel Malek, MD, Gabor Toth, MD, Adnan Siddiqui, MD, John Reavey-Cantwell, MD, Ajith Thomas, MD, Steven W Hetts, MD, Brian T Jankowitz, MD, Osama O Zaidat, MD
doi : 10.1093/neuros/nyab090
Neurosurgery, Volume 89, Issue 1, July 2021, Pages 102–108
Heterogeneous effect of endovascular aneurysm therapy has been observed across different anatomic locations. There is a paucity of data for stent-assisted coiling of middle cerebral artery (MCA) aneurysms.
Does Myelopathy Increase the Morbidity and Mortality of Elective Single-Level Anterior Cervical Discectomy and Fusion? An Updated Propensity-Matched Analysis of 3938 Patients From the American College of Surgeons National Surgical Quality Improvement Program Database
Safwan Alomari, MD, Daniel Lubelski, MD, Amanda N Sacino, MD, PhD, Daniel M Sciubba, MD, Ali Bydon, MD
doi : 10.1093/neuros/nyab091
Neurosurgery, Volume 89, Issue 1, July 2021, Pages 109–115
Myelopathy is thought to be associated with higher morbidity and mortality after anterior cervical discectomy and fusion (ACDF); however, the literature investigating this association has limitations.
Predicting Spinal Surgery Candidacy From Imaging Data Using Machine Learning
Bayard Wilson, MD, MAS, Bilwaj Gaonkar, PhD, Bryan Yoo, MD, Banafsheh Salehi, MD, Mark Attiah, MD, MS, MPH, Diane Villaroman, BS, Christine Ahn, BS, Matthew Edwards, MD, Azim Laiwalla, MD, PhD, Anshul Ratnaparkhi, BA, Ien Li, BA, Kirstin Cook, BA, Joel Beckett, MD, MHS, Luke Macyszyn, MD, MS
doi : 10.1093/neuros/nyab085
Neurosurgery, Volume 89, Issue 1, July 2021, Pages 116–121
The referral process for consultation with a spine surgeon remains inefficient, given a substantial proportion of referrals to spine surgeons are nonoperative.
Commentary: Predicting Spinal Surgery Candidacy From Imaging Data Using Machine Learning
Daryl R Fourney, MD, FRCSC
doi : 10.1093/neuros/nyab127
Neurosurgery, Volume 89, Issue 1, July 2021, Pages E16–E17
no abstract
Falls and Fear of Falling in Shunted Idiopathic Normal Pressure Hydrocephalus—The Idiopathic Normal Pressure Hydrocephalus Comorbidity and Risk Factors Associated With Hydrocephalus Study
Jenny Larsson, MD, Hanna Israelsson, MD, PhD, Anders Eklund, PhD, Lillemor Lundin-Olsson, PhD, Jan Malm, MD, PhD
doi : 10.1093/neuros/nyab094
Neurosurgery, Volume 89, Issue 1, July 2021, Pages 122–128
Gait and balance impairment are typical symptoms of idiopathic normal pressure hydrocephalus (INPH), implicating that falls may afflict these patients.
Commentary: Falls and Fear of Falling in Shunted Idiopathic Normal Pressure Hydrocephalus—The Idiopathic Normal Pressure Hydrocephalus Comorbidity and Risk Factors Associated with Hydrocephalus Study
Mark G Hamilton, MDCM
doi : 10.1093/neuros/nyab126
Neurosurgery, Volume 89, Issue 1, July 2021, Page E18
Patterns and Impact of Electronic Health Records-Defined Depression Phenotypes in Spine Surgery
Maxwell Boakye, MD, MPH, MBA, Mayur Sharma, MD, MCh, Shawn Adams, MD, Thomas Chandler, MS, Dengzhi Wang, MS, Beatrice Ugiliweneza, PhD, MSPH, Doniel Drazin, MD
doi : 10.1093/neuros/nyab096
Neurosurgery, Volume 89, Issue 1, July 2021, Pages E19–E32
Preoperative depression is a risk factor for poor outcomes after spine surgery.
Commentary: Patterns and Impact of Electronic Health Records-Defined Depression Phenotypes in Spine Surgery
Timothy Y Wang, MD, Khoi D Than, MD
doi : 10.1093/neuros/nyab116
Neurosurgery, Volume 89, Issue 1, July 2021, Pages E33–E34
Incidence, Characteristics and Outcomes of Large Vessel Stroke in COVID-19 Cohort: An International Multicenter Study
Priyank Khandelwal, MD, Fawaz Al-Mufti, MD, Ambooj Tiwari, MD, Amit Singla, MD, Adam A Dmytriw, MD, MPH, MSc, Mariangela Piano, MD, Luca Quilici, MD, Guglielmo Pero, MD, Leonardo Renieri, MD, Nicola Limbucci, MD, Mario Mart?nez-Gald?mez, MD, Miguel Schüller-Arteaga, MD, Jorge Galv?n, MD, Juan Francisco Arenillas-Lara, MD, Zafar Hashim, MD, Sanjeev Nayak, MD, Keith Desousa, MD, Hai Sun, MD, PhD, Pankaj K Agarwalla, MD, Anil Nanda, MD, J Sudipta Roychowdhury, MD, Emad Nourollahzadeh, MD, Tannavi Prakash, MD, Chirag D Gandhi, MD, Andrew R Xavier, MD, J Diego Lozano, MD, Gaurav Gupta, MD, Dileep R Yavagal, MD, MBBS
doi : 10.1093/neuros/nyab111
Neurosurgery, Volume 89, Issue 1, July 2021, Pages E35–E41
While there are reports of acute ischemic stroke (AIS) in coronavirus disease 2019 (COVID-19) patients, the overall incidence of AIS and clinical characteristics of large vessel occlusion (LVO) remain unclear.
An Analysis of Medicare Reimbursement for Neurosurgeon Office Visits: 2010 Compared to 2018
Maya T Harrington, BS, Jordan R Pollock, BS, Jack M Haglin, BS, Kent R Richter, BS, Naresh P Patel, MD
doi : 10.1093/neuros/nyab131
Neurosurgery, Volume 89, Issue 1, July 2021, Pages E42–E48
Trends in Medicare billing and procedural reimbursement for outpatient office visits remain unclear within the field of neurosurgery.
Dual Regeneration of Muscle and Nerve by Intramuscular Infusion of Mitochondria in a Nerve Crush Injury Model
Meei-Ling Sheu, PhD, Chiung-Chyi Shen, MD, PhD, Hsi-Kai Tsou, MD, PhD, Meng Yin Yang, MD, PhD, Hong-Lin Su, PhD, Jason Sheehan, MD, PhD, Ming-Hong Chang, MD, Hong-Shiu Chen, MD, Hung-Chuan Pan, MD, PhD
doi : 10.1093/neuros/nyab105
Neurosurgery, Volume 89, Issue 1, July 2021, Pages E49–E59
Peripheral nerve injuries result in muscle denervation and apoptosis of the involved muscle, which subsequently reduces mitochondrial content and causes muscle atrophy. The local injection of mitochondria has been suggested as a useful tool for restoring the function of injured nerves or the brain.
Re-evaluating Biopsy for Recurrent Glioblastoma: A Position Statement by the Christopher Davidson Forum Investigators
Edjah K Nduom, MD, Melanie Hayden Gephart, MD, MAS, Milan G Chheda, MD, Mario L Suva, MD, PhD, Nduka Amankulor, MD, James D Battiste, MD, PhD, Jian L Campian, MD, PhD, Ralph G Dacey, Jr, MD, Sunit Das, MD, PhD, Peter E Fecci, MD, PhD, Constantinos G Hadjipanayis, MD, PhD, Kimberly B Hoang, MD, Ali Jalali, MD, PhD, Daniel Orringer, MD, Akash J Patel, MD, Dimitris Placantonakis, MD, PhD, Analiz Rodriguez, MD, PhD, Isaac Yang, MD, Jennifer S Yu, MD, PhD, Greg J Zipfel, MD, Gavin P Dunn, MD, PhD, Eric C Leuthardt, MD, Albert H Kim, MD, PhD
doi : 10.1093/neuros/nyab063
Neurosurgery, Volume 89, Issue 1, July 2021, Pages 129–132
Patients with glioblastoma (GBM) need bold new approaches to their treatment, yet progress has been hindered by a relative inability to dynamically track treatment response, mechanisms of resistance, evolution of targetable mutations, and changes in mutational burden. We are writing on behalf of a multidisciplinary group of academic neuro-oncology professionals who met at the collaborative Christopher Davidson Forum at Washington University in St Louis in the fall of 2019. We propose a dramatic but necessary change to the routine management of patients with GBM to advance the field: to routinely biopsy recurrent GBM at the time of presumed recurrence. Data derived from these samples will identify true recurrence vs treatment effect, avoid treatments with little chance of success, enable clinical trial access, and aid in the scientific advancement of our understanding of GBM.
Commentary: Developing a Professionalism and Harassment Policy for Organized Neurosurgery
Douglas Kondziolka, MD, James M Markert, MD, Michael McDermott, MD, Shenandoah Robinson, MD, E Sander Connolly, MD
doi : 10.1093/neuros/nyab083
Neurosurgery, Volume 89, Issue 1, July 2021, Page E60
Commentary: Developing a Professionalism and Harassment Policy for Organized Neurosurgery
Brian L Hoh, MD, MBA
doi : 10.1093/neuros/nyab113
Neurosurgery, Volume 89, Issue 1, July 2021, Page E61
Commentary: Developing a Professionalism and Harassment Policy for Organized Neurosurgery
Carl Heilman, MD, Daniel K Resnick, MD
doi : 10.1093/neuros/nyab137
Neurosurgery, Volume 89, Issue 1, July 2021, Page E62
Commentary: Developing a Professionalism and Harassment Policy for Organized Neurosurgery
M Sean Grady, MD
doi : 10.1093/neuros/nyab141
Neurosurgery, Volume 89, Issue 1, July 2021, Pages E63–E64
Commentary: Developing a Professionalism and Harassment Policy for Organized Neurosurgery
John A Wilson, MD
doi : 10.1093/neuros/nyab173
Neurosurgery, Volume 89, Issue 1, July 2021, Page E65
Commentary: The Ki-67 Proliferation Index as a Marker of Time to Recurrence in Intracranial Meningioma
Antonio Dono, MD, Ankush Chandra, MD, MS, Leomar Y Ballester, MD, PhD, Yoshua Esquenazi, MD
doi : 10.1093/neuros/nyab100
Neurosurgery, Volume 89, Issue 1, July 2021, Pages E66–E67
Commentary: Chimeric Antigen Receptor T-Cell Therapy: Updates in Glioblastoma Treatment
Xiaoling Yu, BA, William T Curry, MD, Elizabeth R Gerstner, MD, Daniel P Cahill, MD, PhD, Brian V Nahed, MD, Marcela V Maus, MD, PhD, Bob S Carter, MD, PhD, Bryan D Choi, MD, PhD
doi : 10.1093/neuros/nyab099
Neurosurgery, Volume 89, Issue 1, July 2021, Pages E68–E69
Commentary: Smoking Is an Independent Risk Factor for 90-Day Readmission and Reoperation Following Posterior Cervical Decompression and Fusion
Paul M Arnold, MD, Andrew Webb, PhD, Ravishanker Iyer, PhD
doi : 10.1093/neuros/nyab101
Neurosurgery, Volume 89, Issue 1, July 2021, Pages E70–E71
Commentary: The Validity of the Koos Classification System With Respect to Facial Nerve Function
Nickalus R Khan, MD, Jacques J Morcos, MD
doi : 10.1093/neuros/nyab128
Neurosurgery, Volume 89, Issue 1, July 2021, Page E72
Commentary: Lessons Learned After 760 Neurointerventions via the Upper Extremity Vasculature: Pearls and Pitfalls
Jay U Howington, MD
doi : 10.1093/neuros/nyab144
Neurosurgery, Volume 89, Issue 1, July 2021, Page E73
In Reply: A Retrospective Analysis in 1347 Patients Undergoing Cement Augmentation for Osteoporotic Vertebral Compression Fracture: Is the Sandwich Vertebra at a Higher Risk of Further Fracture?
Ping-Yeh Chiu, MD, Fu-Cheng Kao, MD, Ming-Kai Hsieh, MD, Tsung-Ting Tsai, MD, PhD, Wen-Jer Chen, MD, Chi-Chien Niu, MD, Po-Liang Lai, MD, PhD
doi : 10.1093/neuros/nyab109
Neurosurgery, Volume 89, Issue 1, July 2021, Pages E74–E75
In Reply: Congress of Neurological Surgeons Systematic Review and Evidence-Based Guidelines on the Treatment of Pediatric Hydrocephalus: Update of the 2014 Guidelines
David F Bauer, MD, MPH, Lissa C Baird, MD, Ann Marie Flannery, MD, Paul Klimo, Jr, MD, Mandeep S Tamber, MD, PhD, Dimitrios C Nikas, MD, Catherine A Mazzola, MD, Patricia Rehring, MPH
doi : 10.1093/neuros/nyab098
Neurosurgery, Volume 89, Issue 1, July 2021, Pages E76–E77
Letter: A Phase II and Pharmacodynamic Trial of RO4929097 for Patients With Recurrent/Progressive Glioblastoma
Abdur Rahman, MBBS, Ivan D Lozada-Martinez, MS, Sabrina Rahman, MPH, A H M Ataullah, MBBS, Karen Mu?oz-Baez, MS, Luis Rafael Moscote-Salazar, MD, Amit Agrawal, MCh, Md Moshiur Rahman, MS
doi : 10.1093/neuros/nyab097
Neurosurgery, Volume 89, Issue 1, July 2021, Pages E78–E79
Letter: Focus on Syndrome of Inappropriate Antidiuretic Hormone After Resection of Pituitary Lesions via Transsphenoidal Approach
Kunzhe Lin, MD, Shousen Wang, PhD
doi : 10.1093/neuros/nyab110
Neurosurgery, Volume 89, Issue 1, July 2021, Pages E80–E81
Letter: Contemporary Analysis of Minimal Clinically Important Difference in the Neurosurgical Literature
Sumit Raj, MCh, Pradeep Chouksey, MCh, Adesh Shrivastava, MCh, Rakesh Mishra, MCh, Amit Agrawal, MCh
doi : 10.1093/neuros/nyab115
Neurosurgery, Volume 89, Issue 1, July 2021, Pages E82–E83
In Reply: Contemporary Analysis of Minimal Clinically Important Difference in the Neurosurgical Literature
Thomas M Zervos, MD, Karam Asmaro, MD, Ellen L Air, MD, PhD
doi : 10.1093/neuros/nyab119
Neurosurgery, Volume 89, Issue 1, July 2021, Page E84
Letter: A Review of Passive Brain Mapping Techniques in Neurological Surgery
Karen Mu?oz-Baez, MS, Ivan Lozada-Mart?nez, MS, Luis Rafael Moscote-Salazar, MD, Md Moshiur Raman, MS, Amit Agrawal, MCh
doi : 10.1093/neuros/nyab114
Neurosurgery, Volume 89, Issue 1, July 2021, Pages E85–E86
In Reply: A Review of Passive Brain Mapping Techniques in Neurological Surgery
Jarod L Roland, MD, Carl D Hacker, MD, PhD, Eric C Leuthardt, MD
doi : 10.1093/neuros/nyab118
Neurosurgery, Volume 89, Issue 1, July 2021, Page E87
Letter: Fascicular Topography of the Suprascapular Nerve in the C5 Root and Upper Trunk of the Brachial Plexus: A Microanatomic Study From a Nerve Surgeon's Perspective
Amgad Hanna, MD
doi : 10.1093/neuros/nyab132
Neurosurgery, Volume 89, Issue 1, July 2021, Page E88
Letter: A New Trend of Blended Learning in Neurosurgical Training: Fellowship of Neuroendoscopy
Ehab El Refaee, MDNS, MSc, Ahmed Zohdi, MDNS, MSc, Henry W S Schroeder, MD, PhD
doi : 10.1093/neuros/nyab134
Neurosurgery, Volume 89, Issue 1, July 2021, Pages E89–E90
Letter: Neurosurgery and Manned Spaceflight
Gustavo Frigieri, PhD, Nicollas Nunes Rabelo, MD, Mateus Gonçalves de Sena Barbosa, Yvonne Cagle, PhD, Ralph Pelligra, MD
doi : 10.1093/neuros/nyab133
Neurosurgery, Volume 89, Issue 1, July 2021, Pages E91–E92
Letter: Manifestations of Water and Sodium Disorders Following Surgery for Sellar Lesions
Kunzhe Lin, MD, Shousen Wang, PhD
doi : 10.1093/neuros/nyab139
Neurosurgery, Volume 89, Issue 1, July 2021, Pages E93–E94
Letter: Randomized Trial of Unilateral Focused Ultrasound Subthalamotomy for Parkinson Disease
Ron L Alterman, MD, Michael Schulder, MD
doi : 10.1093/neuros/nyab140
Neurosurgery, Volume 89, Issue 1, July 2021, Pages E95–E96
Letter: Recommendation to Create New Neuropathologic Guidelines for the Post-Mortem Diagnosis of Chronic Traumatic Encephalopathy
Bennet Omalu, MD, MBA, MPH, Jennifer Hammers, DO
doi : 10.1093/neuros/nyab138
Neurosurgery, Volume 89, Issue 1, July 2021, Pages E97–E98
Letter: Patterns of Intermediate- and High-Risk Meningioma Recurrence After Treatment With Postoperative External Beam Radiotherapy
Matthew S Susko, MD, MS, William C Chen, MD, Harish N Vasudevan, MD, PhD, Stephen T Magill, MD, PhD, Calixto-Hope G Lucas, MD, Nancy Ann Oberheim Bush, MD, PhD, David A Solomon, MD, PhD, Philip V Theodosopoulos, MD, Michael W McDermott, MD, Javier E Villanueva-Meyer, MD, Lauren Boreta, MD, Jean L Nakamura, MD, Penny K Sneed, MD, Steve E Braunstein, MD, PhD, David R Raleigh, MD, PhD
doi : 10.1093/neuros/nyab143
Neurosurgery, Volume 89, Issue 1, July 2021, Pages E99–E101
Letter: The Role of Prophylactic Intraventricular Antibiotics in Reducing the Incidence of Infection and Revision Surgery in Pediatric Patients Undergoing Shunt Placement
Adesh Shrivastava, MCh, Sabrina Rahman, MPH, Ivan David Lozada-Martinez, MS, Luis Rafael Moscote-Salazar, MD, Amit Agrawal, MCh, Md Moshiur Rahman, MS
doi : 10.1093/neuros/nyab142
Neurosurgery, Volume 89, Issue 1, July 2021, Pages E102–E103
In Reply: The Role of Prophylactic Intraventricular Antibiotics in Reducing the Incidence of Infection and Revision Surgery in Pediatric Patients Undergoing Shunt Placement
Nikita Lakomkin, MD, Constantinos G Hadjipanayis, MD, PhD
doi : 10.1093/neuros/nyab145
Neurosurgery, Volume 89, Issue 1, July 2021, Page E104
Letter: Enhanced Recovery After Neurosurgery for Brain Tumors – A Critical Reappraisal
Martin Kryspin S?rensen, MD, PhD, Henrik Kehlet, MD, PhD, Christine S?lling, MD, PhD, Kirsten M?ller, MD, PhD, DmSci
doi : 10.1093/neuros/nyab146
Neurosurgery, Volume 89, Issue 1, July 2021, Pages E105–E106
