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http://medilib.ir
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Association between ultra-processed food intake and biological ageing in US adults: findings from National Health and Nutrition Examination Survey (NHANES) 2003–2010
Barbara Rita Cardoso, Junxiu Liu, Priscila Machado, Dayoon Kwon, Daniel W Belsky, Euridice Martinez Steele
doi : 10.1093/ageing/afae268
Volume 53, Issue 12, December 2024, afae268,
The association between ultra-processed food (UPF) intake and markers of biological ageing has been scarcely investigated, despite the evident adverse health effects associated with UPF. This study aimed to test the association between UPF intake and biological ageing, and evaluate how much of this association is accounted for by overall diet quality
Editor’s view—delirium around the world
Roy L Soiza
doi : 10.1093/ageing/afae275
Volume 53, Issue 12, December 2024, afae275,
Studies in geriatric medicine seldom come bigger than the stunning worldwide point prevalence study of delirium in hospitals by Lindroth and colleagues [1]. They looked for delirium across a whopping 1664 different wards in 44 countries, assessing for the presence of delirium in almost 80?000 instances. They found delirium in just over one in six hospitalised patients. There were a number of important findings, including high rates of inappropriate benzodiazepine use and variable use of delirium ascertainment methods, such that the rates are probably underestimated. If you missed it, I also recommend reading the group’s previous paper on delirium assessment and protocols published in a previous issue this year [2]. Much still needs to be done to promote delirium awareness, particularly in non-specialist wards across the world
Deprescribing antihypertensive medication in frail older adults: balancing the complexities of polypharmacy and individualised care
Rob J van Marum
doi : 10.1093/ageing/afae267
Volume 53, Issue 12, December 2024, afae267
Editorial to accompany: Effects of the discontinuation of antihypertensive treatment on neuropsychiatric symptoms and quality of life in nursing home residents with dementia (DANTON): a multicentre, open-label, blinded-outcome, randomised controlled trial [10]
From burden to benefits: new promises of glucose-lowering treatments in older adults
Antoine Christiaens
doi : 10.1093/ageing/afae265
Volume 53, Issue 12, December 2024, afae265
To accompany: Evaluation of glucose-lowering medications in older people: a comprehensive systematic review and network meta-analysis of randomised controlled trials [13]
The association between delirium and falls in older adults in the community: a systematic review and meta-analysis
Charlotte Eost-Telling, Lucy McNally, Yang Yang, Chunhu Shi, Gill Norman, Saima Ahmed, Brenda Poku, Annemarie Money, Helen Hawley-Hague,
doi : 10.1093/ageing/afae270
Volume 53, Issue 12, December 2024, afae270
Systematically review and critically appraise the evidence for the association between delirium and falls in community-dwelling adults aged ?60 years.
Elevated blood pressure variability is associated with an increased risk of negative health outcomes in adults aged 65 and above—a systematic review and meta-analysis
Jordy Saren, Aziz Debain, Fien Loosveldt, Mirko Petrovic, Ivan Bautmans
doi : 10.1093/ageing/afae262
Volume 53, Issue 12, December 2024, afae262
The clinical relevance of blood pressure variability (BPV) is still unknown, despite increasing evidence associating BPV to negative health outcomes (NHOs). There is currently no gold standard to define high BPV and normal reference values for BPV are lacking
Non-pharmacological treatment strategies for anthropometric, physical capacity and physiological indicators among sarcopenic obesity patients: a systematic review of rigorous randomized controlled trials
Haodong Tian, Hansen Li, Xing Zhang, Haowei Liu, Li Huang, Hanglin Yu, Jinlong Wu, Yang Cao, Li Peng
doi : 10.1093/ageing/afae278
Volume 53, Issue 12, December 2024, afae278,
To investigate the effects of non-pharmacological treatments on sarcopenic obesity (SO).
Impact of frailty, malnutrition and socioeconomic status on perioperative outcomes
Brandon Stretton, Andrew E C Booth, Joshua Kovoor, Aashray Gupta, Suzanne Edwards, Tom Hugh, John Maddison, Nicholas J Talley, Mark Plummer
doi : 10.1093/ageing/afae263
Volume 53, Issue 12, December 2024, afae263
Frailty, malnutrition and low socioeconomic status may mutually perpetuate each other in a self-reinforcing and interdependent manner. The intertwined nature of these factors may be overlooked when investigating impacts on perioperative outcomes. This study aimed to investigate the impact of frailty, malnutrition and socioeconomic status on perioperative outcomes
Frailty reduces penumbral volumes and attenuates treatment response in hyperacute ischemic stroke
Esmee Dohle, Benjamin Lewis, Smriti Agarwal, Elizabeth A Warburton, Nicholas R Evans
doi : 10.1093/ageing/afae266
Volume 53, Issue 12, December 2024, afae266,
Frailty—the loss of physiological reserve to withstand a stressor event—is associated with poorer outcomes following acute stroke reperfusion therapies. However, the mechanisms underlying this relationship are poorly understood. This study investigated the association between frailty and penumbral volumes in hyperacute ischemic stroke
Trajectories of functional decline and predictors in long-term care settings: a retrospective cohort analysis of Canadian nursing home residents
Bonaventure Amandi Egbujie, Luke Andrew Turcotte, George Heckman, John P Hirdes
doi : 10.1093/ageing/afae264
Volume 53, Issue 12, December 2024, afae264,
Decline in the ability to perform activities of daily living (ADL) or ‘functional decline’ is a major health concern among aging populations. With intervention, ADL decline may be delayed, prevented or reversed. The capacity to anticipate the trajectory of future functional change can enhance care planning and improve outcome for residents.
Functional dependency and cardiometabolic multimorbidity in older people: pooled analysis of individual-level data from 20 countries
Anying Bai, Qiushi Chen, Pascal Geldsetzer, Muir Gray, Zhilan Xie, Daqian Zhang, Till Baernighausen, Yixin Hu, Yu Jiang, Simiao Chen
doi : 10.1093/ageing/afae269
Volume 53, Issue 12, December 2024, afae269,
The impact of cardiometabolic multimorbidity (CMM) on functional dependency (FD) is well established, but the temporal effect of FD on CMM and its mechanisms remain underexplored.
Association of early-life factors with biological age acceleration and the mediating effect of social environment risks in middle-aged and older adults
Xiaojing Liu, Ming Jin, Zeping Yang, Ziyi Zhang, Ninghao Huang, Tao Huang, Nan Li
doi : 10.1093/ageing/afae272
Volume 53, Issue 12, December 2024, afae272
To investigate associations of maternal smoking, breastfeeding and birth weight with accelerated biological age (BA), and to explore genetic-predicted effect and mediating effect of social environment risks.
Associations of hearing and visual loss with cognitive decline and dementia risk: a 25-year follow-up of the Maastricht Aging Study
Lion M Soons, Kay Deckers, Huibert Tange, Martin P J van Boxtel, Sebastian Köhler
doi : 10.1093/ageing/afae271
Volume 53, Issue 12, December 2024, afae271,
Hearing loss (HL) and visual loss (VL) are recently identified as promising dementia risk factors, but long-term studies with adequate control of other modifiable dementia risk factors are lacking. This 25-year follow-up study investigated the association between objectively measured HL and VL with cognitive decline and incident dementia
Association of immune-mediated diseases with the risk of dementia and brain structure in UK Biobank participants
Jinhua Cai, Heng Rong, Jiongxue Chen, Zhenhong Deng, Sitai Chen, Huanquan Liao, Dong Pan, Yanting Chen, Zhongshan Shi
doi : 10.1093/ageing/afae274
Volume 53, Issue 12, December 2024, afae274,
We aimed to investigate the prospective association of 27 immune-mediated diseases and incident dementia risk and to explore the underlying mechanisms driven by brain structures.
Correction to: Uncertainty and advance care planning in older adults living with frailty. A collection and commentary on the theme of advance care planning
doi : 10.1093/ageing/afae273
Volume 53, Issue 12, December 2024, afae273,
This is a correction to: Pippa Collins, Sarah Hopkins, Helen Milbourn, Simon N Etkind, Uncertainty and advance care planning in older adults living with frailty. A collection and commentary on the theme of advance care planning, Age and Ageing, Volume 53, Issue 9, September 2024, afae146
Correction to: Realising the right to rehabilitation—commentary on ‘reablement, rehabilitation, recovery: everyone’s business
doi : 10.1093/ageing/afae281
Volume 53, Issue 12, December 2024, afae281
This is a correction to: Anne Hendry, Realising the right to rehabilitation—commentary on ‘reablement, rehabilitation, recovery: everyone’s business’, Age and Ageing, Volume 53, Issue 10, October 2024, afae228
Correction to: Modifiable dementia risk associated with smaller white matter volume and altered 1/f aperiodic brain activity: cross-sectional insights from the LEISURE study
doi : 10.1093/ageing/afae289
Volume 53, Issue 12, December 2024, afae289
This is a correction to: Thomas Pace, Jacob M Levenstein, Toomas E Anijärv, Alicia J Campbell, Ciara Treacy, Daniel F Hermens, Sophie C Andrews, Modifiable dementia risk associated with smaller white matter volume and altered 1/f aperiodic brain activity: cross-sectional insights from the LEISURE study, Age and Ageing, Volume 53, Issue 11, November 2024, afae243
