دسترسی یکساله به بیش از ۵۰۰ ژورنال روز جهان موجود در سامانه
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Genetic Analysis in a Swiss Cohort of Bilateral Congenital Cataract
Delia Rechsteiner, MD1,2; Lydia Issler, MD1,2; Samuel Koller, PhD2; Elena Lang, MD1,2; Luzy B?hr2; Silke Feil2; Christoph M. Rüegger, MD3; Raimund Kottke, MD4; Sandra P. Toelle, MD5; Noëmi Zweifel, MD6; Katharina Steindl, MD7; Pascal Joset, PhD7; Markus Zweier, PhD7; Aude-Annick Suter, MD7; Laura Gogoll, MD7; Cordula Haas, PhD8; Wolfgang Berger, PhD2,9,10; Christina Gerth-Kahlert, MD1
doi : 10.1001/jamaophthalmol.2021.0385
JAMA Ophthalmol. 2021;139(7):691-700
Importance Identification of geographic population-based differences in genotype and phenotype heterogeneity are important for targeted and patient-specific diagnosis and treatment, counseling, and screening strategies.
Effect of Intravitreous Anti–Vascular Endothelial Growth Factor vs Sham Treatment for Prevention of Vision-Threatening Complications of Diabetic Retinopathy
Raj K. Maturi, MD1; Adam R. Glassman, MS2; Kristin Josic, PhD2; Andrew N. Antoszyk, MD3; Barbara A. Blodi, MD4; Lee M. Jampol, MD5; Dennis M. Marcus, MD6; Daniel F. Martin, MD7; Michele Melia, ScM2; Hani Salehi-Had, MD8; Cynthia R. Stockdale, MSPH2; Omar S. Punjabi, MD3; Jennifer K. Sun, MD, MPH9; for the DRCR Retina Network
doi : 10.1001/jamaophthalmol.2021.0606
JAMA Ophthalmol. 2021;139(7):701-712
Importance The role of anti–vascular endothelial growth factor injections for the management of nonproliferative diabetic retinopathy (NPDR) without center-involved diabetic macular edema (CI-DME) has not been clearly established.
Prevalence of Visual Acuity Loss or Blindness in the US
Abraham D. Flaxman, PhD1; John S. Wittenborn, BS2; Toshana Robalik, BS1; Rohit Gulia, MS1; Robert B. Gerzoff, MS3; Elizabeth A. Lundeen, PhD, MPH4; Jinan Saaddine, MD, MPH4; David B. Rein, PhD, MPA2; for the Vision and Eye Health Surveillance System study group
doi : 10.1001/jamaophthalmol.2021.0527
JAMA Ophthalmol. 2021;139(7):713-724
Importance Globally, more than 250 million people live with visual acuity loss or blindness, and people in the US fear losing vision more than memory, hearing, or speech. But it appears there are no recent empirical estimates of visual acuity loss or blindness for the US.
Visual Acuity, Vitreous Hemorrhage, and Other Ocular Outcomes After Vitrectomy vs Aflibercept for Vitreous Hemorrhage Due to Diabetic Retinopathy
Adam R. Glassman, MS1; Wesley T. Beaulieu, PhD1; Maureen G. Maguire, PhD2; Andrew N. Antoszyk, MD3; Clement C. Chow, MD4; Michael J. Elman, MD5; Lee M. Jampol, MD6; Hani Salehi-Had, MD7; Jennifer K. Sun, MD, MPH8; for the DRCR Retina Network
doi : 10.1001/jamaophthalmol.2021.1110
JAMA Ophthalmol. 2021;139(7):725-733
Importance Although there were no differences in mean visual acuity (VA) over 24 weeks after vitrectomy with panretinal photocoagulation (PRP) vs aflibercept in a randomized clinical trial among eyes with vitreous hemorrhage due to proliferative diabetic retinopathy (PDR), post hoc analyses may influence treatment choices.
Comparison of Central Macular Fluid Volume With Central Subfield Thickness in Patients With Diabetic Macular Edema Using Optical Coherence Tomography Angiography
Qi Sheng You, MD, PhD1; Kotaro Tsuboi, MD1; Yukun Guo, MS1; Jie Wang, MS1,2; Christina J. Flaxel, MD1; Steven T. Bailey, MD1; David Huang, MD, PhD1; Yali Jia, PhD1,2; Thomas S. Hwang, MD1
doi : 10.1001/jamaophthalmol.2021.1275
JAMA Ophthalmol. 2021;139(7):734-741
Importance Diabetic macular edema (DME) is the predominant cause of visual impairment in patients with type 1 or 2 diabetes. Automated fluid volume measurements using optical coherence tomography (OCT) may improve the diagnostic accuracy of DME screening.
Enlargement of Geographic Atrophy From First Diagnosis to End of Life
Johanna M. Colijn, MD, MSc1,2; Bart Liefers, MSc3; Nichole Joachim, BSc(Hons), PhD4; Timo Verzijden, MSc1,2; Magda A. Meester-Smoor, PhD1,2; Marc Biarnés, MSc5,6; Jordi Monés, MD, PhD5,6; Paulus T. V. M. de Jong, MD, PhD7; Johannes R. Vingerling, MD, PhD1; Paul Mitchell, MD, PhD8; Clara I. S?nchez, PhD9,10; Jie J. Wang, MMed, PhD8,11; Caroline C. W. Klaver, MD, PhD1,2,12,13; for the EyeNED Reading Center and EYE-RISK Consortium
doi : 10.1001/jamaophthalmol.2021.1407
JAMA Ophthalmol. 2021;139(7):743-750
Importance Treatments for geographic atrophy (GA), a late stage of age-related macular degeneration (AMD), are currently under development. Understanding the natural course is needed for optimal trial design. Although enlargement rates of GA and visual acuity (VA) in the short term are known from clinical studies, knowledge of enlargement in the long term, life expectancy, and visual course is lacking.
Association Between Visual Impairment and Depression in Patients Attending Eye Clinics
Mariacristina Parravano, MD1; Davide Petri, MSc2; Erica Maurutto, MD3; Ersilia Lucenteforte, PhD2; Francesca Menchini, MD3; Paolo Lanzetta, MD3; Monica Varano, MD1; Ruth M. A. van Nispen, PhD4; Gianni Virgili, MD5,6
doi : 10.1001/jamaophthalmol.2021.1557
JAMA Ophthalmol. 2021;139(7):753-761
Importance Given that depression is treatable and some ocular diseases that cause visual loss are reversible, early identification and treatment of patients with visual impairment who are most at risk of depression may have an important influence on the well-being of these patients.
Association of the MYOC p.(Gln368Ter) Variant With Glaucoma in a Finnish Population
Perttu J. Liuska, MD1; Susanna Lemmel?, PhD2,3; Aki S. Havulinna, DSc2,3; Kai Kaarniranta, MD, PhD4; Hannu Uusitalo, MD, PhD5; Hannele Laivuori, MD, PhD2,6; Tuomo Kiiskinen, MD2; Mark J. Daly, PhD2; Aarno Palotie, MD, PhD2; Joni A. Turunen, MD, PhD1,7; for the FinnGen Consortium
doi : 10.1001/jamaophthalmol.2021.1610
JAMA Ophthalmol. 2021;139(7):762-768
Importance The c.1102C>T, p.(Gln368Ter) variant in the myocilin (MYOC) gene is a known risk allele for glaucoma. It is the most common MYOC risk variant for glaucoma among individuals of European ancestry, and its prevalence is highest in Finland. Furthermore, exfoliation syndrome has high prevalence in Scandinavia, making the Finnish population ideal to study the association of the variant with different types of glaucoma.
Defining Nonadherence and Nonpersistence to Anti–Vascular Endothelial Growth Factor Therapies in Neovascular Age-Related Macular Degeneration
Mali Okada, MMed1; Tien Yin Wong, MD, PhD2,3; Paul Mitchell, MD, PhD4; Bora Eldem, MD5; S. James Talks, MB Bchir6; Tariq Aslam, PhD7; Vincent Daien, MD, PhD8; Francisco J. Rodriguez, MD9; Richard Gale, MD10; Jane Barratt, MSc, PhD11; Robert P. Finger, MD, PhD12; Anat Loewenstein, MD13
doi : 10.1001/jamaophthalmol.2021.1660
JAMA Ophthalmol. 2021;139(7):769-776
Importance Poor adherence or persistence to treatment can be a barrier to optimizing clinical practice (real-world) outcomes to intravitreal injection therapy in patients with neovascular age-related macular degeneration (nAMD). Currently, there is a lack of consensus on the definition and classification of adherence specific to this context.
Ocular Assessments of a Series of Newborns Gestationally Exposed to Maternal COVID-19 Infection
Ol?via Pereira Kiappe, MD, MSc1; Natasha Ferreira Santos da Cruz, MD1; Paulo Alberto Cervi Rosa, MD1; Luciana Arrais, MD1; Nilva Simeren Bueno de Moraes, MD, PhD1
doi : 10.1001/jamaophthalmol.2021.1088
JAMA Ophthalmol. 2021;139(7):777-780
Importance Congenital viral infections leading to ocular abnormalities are frequent and devastating. As ophthalmological manifestations of COVID-19 in newborns are still unknown, it is important to clarify if SARS-CoV-2 could be associated with ocular abnormalities.
Association of Structural Changes in the Brain and Retina After Long-Duration Spaceflight
Karina Marshall-Goebel, PhD1; Brandon R. Macias, PhD2; Larry A. Kramer, MD3; Khader M. Hasan, PhD3; Connor Ferguson, MS4; Nimesh Patel, PhD5; Robert J. Ploutz-Snyder, PhD6; Stuart M. C. Lee, PhD1; Doug Ebert, PhD1; Ashot Sargsyan, MD1; Scott Dulchavsky, MD7; Alan R. Hargens, PhD8; Michael B. Stenger, PhD2; Steven Laurie, PhD1
doi : 10.1001/jamaophthalmol.2021.1400
JAMA Ophthalmol. 2021;139(7):781-784
Importance Long-duration spaceflight induces structural changes in the brain and eye. Identification of an association between cerebral and ocular changes could help determine if there are common or independent causes and inform targeted prevention strategies or treatments.
Detection and Referral of Orbital and Ocular Injuries Associated With Intimate Partner Violence Following an Educational and Screening Initiative in an Emergency Department
Salma A. Dawoud, MD1; Ali R. Cohen, MD2; Lynette M. Renner, PhD, MSW3; Thomas J. Clark, MD4; M. Bridget Zimmerman, PhD5; Erin M. Shriver, MD1
doi : 10.1001/jamaophthalmol.2021.1546
JAMA Ophthalmol. 2021;139(7):785-789
Importance Intimate partner violence (IPV) is a substantial cause of morbidity and mortality in the US. Previous studies indicate gaps in identifying and referring female patients with IPV-associated orbital and ocular injuries to ancillary services.
Racial/Ethnic Disparities and Barriers to Diabetic Retinopathy Screening in Youths
Chrystal G. Thomas, MMS1; Roomasa Channa, MD2; Laura Prichett, PhD, MHS3; T. Y. Alvin Liu, MD4; Michael D. Abramoff, MD, PhD5,6,7; Risa M. Wolf, MD1
doi : 10.1001/jamaophthalmol.2021.1551
JAMA Ophthalmol. 2021;139(7):791-795
Importance Diabetic retinopathy is a major complication of diabetes for which regular screening improves visual health outcomes, yet adherence to screening is suboptimal.
Practicality of Prophylactic Aflibercept to Reduce Diabetic Retinopathy Progression
Rajendra S. Apte, MD, PhD1; Christopher K. Hwang, MD, PhD1
doi : 10.1001/jamaophthalmol.2021.0624
JAMA Ophthalmol. 2021;139(7):713-714
Prevention of Severe Nonproliferative Diabetic Retinopathy Progression With More at Stake Than Visual Acuity
Jennifer I. Lim, MD1,2
doi : 10.1001/jamaophthalmol.2021.0625
JAMA Ophthalmol. 2021;139(7):714-716
Updated Numbers on the State of Visual Acuity Loss and Blindness in the US
Emily Y. Chew, MD1
doi : 10.1001/jamaophthalmol.2021.0521
JAMA Ophthalmol. 2021;139(7):723-724
Automated Retinal Fluid Volume Quantification
Aaron Y. Lee, MD, MSCI1; Amy Yuan, MD1
doi : 10.1001/jamaophthalmol.2021.1284
JAMA Ophthalmol. 2021;139(7):741-742
Therapeutic Margin for Geographic Atrophy
SriniVas R. Sadda, MD1,2; David Sarraf, MD2,3
doi : 10.1001/jamaophthalmol.2021.1414
JAMA Ophthalmol. 2021;139(7):751-752
Intimate Partner Violence–Related Oculofacial Injuries During the COVID-19 Pandemic
Dane H. Slentz, MD1; Andrew W. Joseph, MD, MPH2; Shannon S. Joseph, MD3
doi : 10.1001/jamaophthalmol.2021.1543
JAMA Ophthalmol. 2021;139(7):789-790
Bilateral Central and Peripheral Vision Loss in an Otherwise Asymptomatic Woman
Emilia Maggio, MD1; Andrea Palamara, MD1; Grazia Pertile, MD1
doi : 10.1001/jamaophthalmol.2020.5278
JAMA Ophthalmol. 2021;139(7):796-797
Retinal Artery Occlusion After a Dog Bite in a 55-Year-Old Man
Heather Tamez, MD1; Shriji N. Patel, MD1
doi : 10.1001/jamaophthalmol.2020.5282
JAMA Ophthalmol. 2021;139(7):798-799
Progressive Scleral Thinning in a Middle-aged Woman
Hasenin Al-khersan, MD1; Guillermo Amescua, MD1; Janet L. Davis, MD1
doi : 10.1001/jamaophthalmol.2020.5287
JAMA Ophthalmol. 2021;139(7):800-801
Iris Mass in a 14-Month-Old Boy
Noy Ashkenazy, MD1; Scott D. Walter, MD, MSc1,2; J. William Harbour, MD1,3
doi : 10.1001/jamaophthalmol.2020.5301
JAMA Ophthalmol. 2021;139(7):802-803
Cost Analysis of Intravitreal Aflibercept vs Vitrectomy With Panretinal Photocoagulation for Vitreous Hemorrhage From Proliferative Diabetic Retinopathy
Benjamin K. Young, MD, MS1; Mark W. Johnson, MD1; Thomas J. Wubben, MD, PhD1
doi : 10.1001/jamaophthalmol.2021.1565
JAMA Ophthalmol. 2021;139(7):804-805
Photocoagulation of Transudative Type 2 Retinal Arteriovenous Malformation
Timothy Janetos, MD1; Maria Vittoria Cicinelli, MD2,3; Rukhsana G. Mirza, MD1; Lee M. Jampol, MD1
doi : 10.1001/jamaophthalmol.2021.1436
JAMA Ophthalmol. 2021;139(7):805-807
Spontaneous Closure of a Macular Hole After Nd:YAG Laser Treatment for Valsalva Retinopathy in Pregnancy
Zhongxu Tian, MD1; Haoyu Li, MRes2; Yaqin Zhu, MD1; Xiaohong Jin, MD1; Yumin Li, MD1; Xian Li, MRes3; Jiuke Li, MD1
doi : 10.1001/jamaophthalmol.2021.1619
JAMA Ophthalmol. 2021;139(7):807-809
Peripapillary Retinal and Choroidal Penetration of a Dexamethasone Intravitreal Implant
Hyeong Min Kim, MD, MSc1; Se Joon Woo, MD, PhD1
doi : 10.1001/jamaophthalmol.2021.1717
JAMA Ophthalmol. 2021;139(7):e211717
Bilateral Acute Macular Neuroretinopathy After Vaccination Against SARS-CoV-2
Benedikt A. J. Book, MD1; Barbara Schmidt, MD2; Andreas M. H. Foerster, MD1
doi : 10.1001/jamaophthalmol.2021.2471
JAMA Ophthalmol. 2021;139(7):e212471
Vision Impairment and Its Association With Preventive Care Use
Qi Zhi Clayton Yang1
doi : 10.1001/jamaophthalmol.2021.1233
JAMA Ophthalmol. 2021;139(7):809-810
Vision Impairment and Its Association With Preventive Care Use—Reply
Lama Assi, MD1,2; Nicholas S. Reed, AuD2,3,4; Bonnielin K. Swenor, PhD, MPH1,3,4
doi : 10.1001/jamaophthalmol.2021.1236
JAMA Ophthalmol. 2021;139(7):810-811
Association of the Indoor Environment With Dry Eye Metrics—Some Additional Evidence to Pursue
Xiao-Man Liu, MM1; Xiao-Qin He, MM1; Hong-Lin Chen, MD2
doi : 10.1001/jamaophthalmol.2021.1600
JAMA Ophthalmol. 2021;139(7):811
Association of the Indoor Environment With Dry Eye Metrics—Some Additional Evidence to Pursue—Reply
Anat Galor, MD1,2; Naresh Kumar, PhD3
doi : 10.1001/jamaophthalmol.2021.1597
JAMA Ophthalmol. 2021;139(7):812
