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Maculopapular cutaneous mastocytosis in children

Maculopapular cutaneous mastocytosis in children

MPCM in patients with childhood-onset mastocytosis.

(A-G) Most children have characteristic large, brown lesions of different sizes (polymorphic). Lesion margins can be sharp (A and E) or indistinct (B and G) and elevated (C and E) or flat (B and F). Nodular lesions present during infancy (C and E) may develop into plaques or macules at the age of 5 to 10 years (D and F) before they regress by adolescence. (G) Lesions on the forehead are characteristic for polymorphic MPCM.

(H and I) Few pediatric patients show small monomorphic lesions like the ones observed in adults.

(J) Atypical variants can also occur in children, such as one with yellow, firm lesions, which was previously also termed "xanthelasmoid CM."
MPCM: maculopapular cutaneous mastocytosis; CM: cutaneous mastocytosis.
Reproduced from: Hartmann K, Escribano L, Grattan C, et al. Cutaneous manifestations in patients with mastocytosis: Consensus report of the European Competence Network on Mastocytosis; the American Academy of Allergy, Asthma & Immunology; and the European Academy of Allergology and Clinical Immunology. J Allergy Clin Immunol 2015. Illustration used with the permission of Elsevier Inc. All rights reserved.
Graphic 105581 Version 5.0

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