Stratification of opioid infusions for head and neck surgery | ||
Degree of postoperative pain | Opioid regimen | |
None to mild | Remifentanil infusion +/– fentanyl 1 mcg/kg total dose | |
Mild to moderate | Remifentanil infusion + fentanyl 1 to 3 mcg/kg total dose OR Alfentanil infusion | |
Moderate to severe | Sufentanil infusion +/– remifentanil infusion* OR Fentanyl infusion +/– remifentanil infusion* | |
Opioid doses for head and neck surgery¶[1-23] | ||
Opioid | IV load | IV infusion |
Fentanyl | 3 to 7 mcg/kgΔ | 0.7 to 2.5 mcg/kg/hour◊ |
Sufentanil | 0.25 to 1.5 mcg/kgΔ TCI: 0.4 to 0.5 ng/mL | 0.2 to 0.3 mcg/kg/hour TCI: 0.2 to 0.65 ng/mL |
Alfentanil | 20 to 40 mcg/kg TCI: 100 to 200 ng/mL | 0.25 to 1.5 mcg/kg/minute TCI: 60 to 150 ng/mL |
Remifentanil | 0.5 to 2 mcg/kg TCI: 4 ng/mL | 0.05 to 0.3 mcg/kg/minute TCI: 1.5 to 9 ng/mL |
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