Type of treatment | Definition |
Episodic (on demand) treatment | Replacement factor given at the time of bleeding |
Continuous (regular) prophylaxis | Replacement factor given to prevent bleeding for at least 45 of 52 weeks (85%) of a year |
| Continuous prophylaxis started before age three years and before the second large joint bleed |
| Continuous prophylaxis started after two or more large joint bleeds but before the onset of chronic arthropathy |
| Continuous prophylaxis started after the onset of arthropathy to prevent further damage |
Intermittent (periodic) prophylaxis | Replacement factor given to prevent bleeding for short periods of time such as during and after surgery |
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