August 2025
August 2025
| Prognosis | Age (years) | |||
| <35 | 35 to 37 | 38 to 40 | 41 to 42 | |
| Cleavage-stage embryos | ||||
| Euploid* | 1 | 1 | 1 | 1 |
| Other favorable¶ | 1 | 1 | ≤3 | ≤4 |
| Embryos not euploid* or favorable¶ | ≤2 | ≤3 | ≤4 | ≤5 |
| Blastocysts | ||||
| Euploid* | 1 | 1 | 1 | 1 |
| Other favorable¶ | 1 | 1 | ≤2 | ≤3 |
| Embryos not euploid* or favorable¶ | ≤2 | ≤2 | ≤3 | ≤3 |
Justification for transferring additional embryos beyond recommended limits should be clearly documented in the patient's medical record.
ASRM: American Society for Reproductive Medicine; FET: frozen embryo transfer; IVF: in vitro fertilization.
* Demonstrated euploid embryos, best prognosis.
¶ Other Favorable = any 1 of these criteria: Fresh cycle: expectation of 1 or more high-quality embryos available for cryopreservation or previous live birth after a prior transfer with sibling embryo(s); FET cycle: availability of vitrified day-5 or day-6 blastocysts, euploid embryos, first FET cycle, or previous live birth after an IVF cycle.
Reproduced from: Practice Committee of the American Society for Reproductive Medicine, Practice Committee of the Society for Assisted Reproductive Technology. Guidance on the limits to the number of embryos to transfer: committee opinion. Fertil Steril 2017; 107:901. Table used with the permission of Elsevier Inc. All rights reserved.
Guidance reaffirmed and original table modified based on: Practice Committee of the American Society for Reproductive Medicine, Practice Committee of the Society for Assisted Reproductive Technology. Guidance on the limits to the number of embryos to transfer: a committee opinion. Fertil Steril 2021; 116:651.
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