Prefix | Target substem (also called Infix)* | Source substem (omitted in mAbs named after 2017)¶ | SuffixΔ | ||
Substem | Definition | Substem | Definition | ||
Random and distinctive | -ami | Serum amyloid protein (SAP)/amyloidosis | -a | Rat | All products named before 2022:
Products named from 2022 onward use one of the following:
|
-ba | Bacterial | -axo | Rat-mouse | ||
-ci | Cardiovascular | -e | Hamster | ||
-eni | Enzyme inhibition | -i | Primate | ||
-fung | Fungal | -o | Mouse | ||
-gro | Skeletal muscle mass related growth factors and receptors | -u | Human | ||
-ki | Cytokine and cytokine receptors | -xi | Chimeric | ||
-ler | Allergen | -xizu | Chimeric-humanized | ||
-ne | Neural | -zu | Humanized | ||
-os | Bone | ||||
-pru | Immunosuppressive | ||||
-sto | Immunostimulatory | ||||
-toxa | Toxin | ||||
-ta | Tumor | ||||
-vet | Veterinary use | ||||
-vi | Viral |
mAb: monoclonal antibody.
* The final letter could be omitted if it interfered with pronunciation.
¶ Non-human species are no longer used due to high immunogenicity.
Δ Changes to the suffix were made in 2022 to reduce sound-alikes and to specify the immunoglobulin structure.