Assay | Target(s) | Prevalence (%) | Sensitivity (%) | Specificity (%) | Positive predictive value (%) | Negative predictive value (%) | Reference, year |
Nose, groin, and throat assays | |||||||
Xpert MRSA - third generation | Staphylococcal protein A gene (spa), mecA, SCCmec-orfX junction | 5.0 | 71.4 | 98.4 | 70.6 | 98.5 | [1], 2019 |
Xpert MRSA - third generation | Staphylococcal protein A gene (spa), mecA, mecC, SCCmec-orfX junction | 4.7 | 82.3 | 96.8 | 55.7 | 99.1 | [1], 2019 |
Xpert MRSA - third generation | Staphylococcal protein A gene (spa), mecA, mecC, SCCmec-orfX junction | 2.3 | 86.9 | 97.9 | 47.7 | 99.7 | [2], 2017 |
Xpert MRSA - Next Generation | Staphylococcal protein A gene (spa), mecA, mecC, SCCmec-orfX junction (incorporates new primer designs and other refinements) | 4.3 | 84.3 | 99.1 | 81.4 | 99.3 | [1], 2019 |
Xpert MRSA - Next Generation | Staphylococcal protein A gene (spa), mecA, mecC, SCCmec-orfX junction (incorporates new primer designs and other refinements) | 1.2 | 77.8 | 99.2 | 47.6 | 99.9 | [2], 2017 |
BD MAX MRSA XT - third generation | mecA, mecC, SCCmec-orfX junction | 10 | 66.7 | 97.1 | 72.7 | 97.2 | [3], 2015 |
LightCycler MRSA Advanced Test | Insertion site SCCmec at orfX junction | 6.8 | 98.3 | 98.9 | 86.7 | 99.9 | [4], 2015 |
Blood assays | |||||||
BD MAX Staph SR assay - second generation | SCCmec right extremity junction, thermostable nuclease (nuc), mecA, mecC | 10.4 | 100 | 100 | 100 | 100 | [5], 2015 |
Xpert MRSA/SA BC - second generation | Staphylococcal protein A gene (spa), mecA, SCCmec-orfX junction | 7.3 | 100 | 100 | 100 | 100 | [6], 2011 |
Xpert MRSA/SA SSTI - second generation | Staphylococcal protein A gene (spa), mecA, SCCmec-orfX junction | 14 | 98.3 | 99.4 | 96.6 | 99.7 | [7], 2009 |
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