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Goal blood pressure according to baseline risk for cardiovascular disease and method of measuring blood pressure

Goal blood pressure according to baseline risk for cardiovascular disease and method of measuring blood pressure
  Casual/conventional office blood pressure (manual or oscillometric measurement without proper patient preparation or technique)* AOBPM, standardized office blood pressure, daytime ABPM, or home blood pressure
Higher-risk populationΔ
  • Known ASCVD
  • Heart failure
  • Diabetes mellitus
  • Chronic kidney disease
  • Age ≥65 years§
  • Calculated 10-year risk of ASCVD event ≥10%¥
125 to 130/<80 120 to 125/<80
Lower-risk
  • None of the above risk factors
130 to 139/<90 125 to 135/<90
  • All target ranges presented above are in mmHg.
  • On average, blood pressure readings are 5 to 15 mmHg lower with standardized or out-of-office methods of measurement (ie, AOBPM, daytime ABPM, home blood pressure) than with casual/conventional methods of office measurement (ie, manual auscultatory or oscillometric measurement without proper patient preparation or technique). However, it is critical to realize that this average difference in blood pressures according to the methodology of measurement applies to the population and not the individual. Some patients do not experience a white coat effect, and, therefore, there is some uncertainty in setting goals that are specific to the method of measurement.
  • When treating to these goals, a patient may (inadvertently) attain a blood pressure below the given target. Provided the patient does not develop symptoms, side effects, or adverse events as a result of the treatment regimen, then reducing or withdrawing antihypertensive medications is unnecessary.
  • Less aggressive goals than those presented in the table may be appropriate for specific groups of patients, including those with postural hypotension, the frail older adult patient, and those with side effects to multiple antihypertensive medications.

ABPM: ambulatory blood pressure monitoring; ACC/AHA: American College of Cardiology/American Heart Association; AOBPM: automated oscillometric blood pressure monitoring; ASCVD: atherosclerotic cardiovascular disease.

* Office blood pressure must be performed adequately in order to use such measurements to manage patients. Critical to an adequate office assessment of blood pressure are proper patient positioning (eg, seated in a chair, feet flat on the floor, arm supported, remove clothing covering the location of cuff placement) and proper technique (eg, calibrated device, proper-sized cuff). The average of multiple measurements should be used for management. Refer to UpToDate topics on measurement of blood pressure. Office readings should not be used to manage blood pressure unless it is performed adequately.

¶ Home blood pressure, like office blood pressure, must be performed adequately in order for the measurements to be used to manage patients. First, the accuracy of the home blood pressure device must be verified in the clinician's office. Second, the clinician should verify that the cuff and bladder that the patient will use are the appropriate size. Third, patients should measure their pressure after several minutes of rest and while seated in a chair (back supported and feet flat on the floor) with their arm supported (eg, resting on a table). Fourth, the blood pressure should be measured at different times per day and over multiple days. The average value of these multiple measurements is used for management. Home blood pressure readings should not be used to manage blood pressure unless it is performed adequately and in conjunction with office blood pressure or ambulatory blood pressure.

Δ The level of evidence supporting the lower goal in higher-risk individuals is stronger for some risk groups (eg, patients with known coronary heart disease, patients with a calculated 10-year risk ≥15%, chronic kidney disease) than for other risk groups (eg, patients with diabetes, patients with a prior stroke). Refer to UpToDate topics on goal blood pressure for a discussion of the evidence.

◊ Prior history of coronary heart disease (acute coronary syndrome or stable angina), prior stroke or transient ischemic attack, prior history of peripheral artery disease.

§ In older adults with severe frailty, dementia, and/or a limited life expectancy, or in patients who are nonambulatory or institutionalized (eg, reside in a skilled nursing facility), we individualize goals and share decision-making with the patient, relatives, and caretakers, rather than targeting one of the blood pressure goals in the table.

¥ The 2013 ACC/AHA cardiovascular risk assessment calculator should be used to estimate 10-year cardiovascular disease risk.

‡ In the large subgroup of patients who have an initial (pretreatment) blood pressure ≥140/≥90 mmHg, but who do not have any of the other listed cardiovascular risk factors, some experts would set a more aggressive blood pressure goal of <130/<80 mmHg rather than those presented in the table. This more aggressive goal would likely reduce the chance of developing severe hypertension and ultimately lower the relative risk of cardiovascular events in these lower-risk patients over the long term. However, the absolute benefit of more aggressive blood pressure lowering in these patients is comparatively small, and a lower goal would require more intensive pharmacologic therapy and corresponding side effects.
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