Kidney mass biopsy

Kidney mass biopsy should be considered whenever it might influence counseling and management.

Kidney mass biopsy should be considered when a mass is suspected to be hematologic, metastatic, inflammatory, or infectious.

Kidney mass biopsy is not required for:

Young/healthy patients who are unwilling to accept the potential uncertainties associated with a false-negative result on kidney mass biopsy and who will choose surgery even if the kidney mass biopsy is negative for cancer; or
Older/frail patients who will be managed conservatively independent of kidney mass biopsy.

Counsel regarding rationale, positive/negative predictive values, potential risks, and nondiagnostic rates of kidney mass biopsy.

Multiple core biopsies are preferred over fine-needle aspiration.

Adapted with permission of AUA from: Campbell SC, Clark PE, Chang SS, et al: Renal Mass and Localized Renal Cancer: Evaluation, Management, and Follow-Up: AUA Guideline Part I. J Urol 2021; 206: 199. Copyright © 2021 American Urological Association.

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Kidney mass biopsy