The mean (± standard deviation) end-tidal concentration of sevoflurane in oxygen for each of the six age groups from neonates to older children up to 12 years of age. The data for MAC at 30 years of age were obtained from Scheller, et al[1]. MAC is the minimal alveolar concentration of an inhalation agent required to prevent movement in response to a noxious stimulus in 50 percent of subjects.
Reference:
- Scheller MS, Saidman LJ, Partridge BL. MAC of sevoflurane in humans and the New Zealand white rabbit. Can J Anaesth 1988; 35:153.
From: Lerman J, Sikich N, Kleinman S, Yentis S. The pharmacology of sevoflurane in infants and children. Anesthesiology 1994; 80:814. Copyright © 1994 American Society of Anesthesiologists. Reproduced with permission from Wolters Kluwer Health. Unauthorized reproduction of this material is prohibited.
