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Frequency of maternal blood lead follow-up testing during pregnancy

Frequency of maternal blood lead follow-up testing during pregnancy
Venous* blood lead level (BLL; microgram/dL) Perform follow-up test(s)
<5 None (no follow-up testing is indicated).
5 to 14 Within 1 month. Obtain a maternal BLLΔ or cord BLL at delivery.
15 to 24 Within 1 month and then every 2 to 3 months. Obtain a maternal BLLΔ or cord BLL at delivery. More frequent testing may be indicated based on risk factor history.
25 to 44 Within 1 to 4 weeks and then every month. Obtain a maternal BLLΔ or cord BLL at delivery.
≥45 Within 24 hours and then at frequent intervals depending on clinical interventions and trend in BLLs. Consultation with a clinician experienced in the management of pregnant women with BLLs in this range is strongly advised. Obtain a maternal BLL or cord BLL at delivery.

* Venous blood sample is recommended for maternal blood lead testing.

¶ The higher the blood lead level on the screening test, the more urgent the need for confirmatory testing.

Δ If possible, obtain a maternal blood lead level before delivery because blood lead levels tend to increase over the course of pregnancy.

Reproduced from: Ettinger AS, Gurthrie Wengrovitz A (Eds). Guidelines for the identification and management of lead exposure in pregnant and lactating women. US Department of Health and Human Services, Atlanta, GA 2010. https://stacks.cdc.gov/view/cdc/147837 (Accessed on March 24, 2021).

Supported by:

  1. Committee on Obstetric Practice. Committee opinion No. 533: Lead screening during pregnancy and lactation. Obstet Gynecol 2012; 120:416. Reaffirmed 2018.
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