Technique | Study | Study endpoint | Closure rate | Adverse events |
RFA | Proebstle[1] | 6 months | 99.6% | DVT: 0% Paresthesia: 3.2% Phlebitis: 0.8% |
VeClose Trial[2] | 3 months | 96% | DVT: 0% Paresthesia: 3% Phlebitis: 3% | |
Laser ablation | Min[3] | 2 years | 93.4% | DVT: 0% Paresthesia: 1.1% |
PEM (1% POL) | VANISH-1[4] | 8 week closure rate with 1% polidocanol | 80.4% | DVT: 1.9% Phlebitis: 7.7% |
VANISH-2[5] | 86.2% | |||
MOCA | Elias[6] | 6 months | 96.7% | No PE or CVA events |
Cyanoacrylate glue | VeClose Trial | 3 months | 99% VenaSeal | DVT: 0% Paresthesia: 3% Phlebitis: 4% |
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