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خرید پکیج
تعداد آیتم قابل مشاهده باقیمانده : -21 مورد

Comorbidities the CDC classifies as risk factors for severe COVID-19*

Comorbidities the CDC classifies as risk factors for severe COVID-19*
Established, probable, and possible risk factors (comorbidities that have been associated with severe COVID-19 in at least 1 meta-analysis or systematic review, in observational studies, or in case series):
  • Age ≥65 years
  • Asthma
  • Cancer
  • Cerebrovascular disease
  • Children with certain underlying conditionsΔ
  • Chronic kidney disease
  • Chronic lung disease (interstitial lung disease, pulmonary embolism, pulmonary hypertension, bronchiectasis, COPD)
  • Chronic liver disease (cirrhosis, non-alcoholic fatty liver disease, alcoholic liver disease, autoimmune hepatitis)
  • Cystic fibrosis
  • Diabetes mellitus, type 1 and type 2
  • Disabilities (eg, ADHD, cerebral palsy, congenital malformations, learning disabilities, limitations with self-care or activities of daily living, neurodevelopmental disorders, spinal cord injuries)
  • Heart conditions (such as heart failure, coronary artery disease, or cardiomyopathies)
  • Hemophilia
  • HIV
  • Mental health disorders (mood disorders including depression, schizophrenia spectrum disorders)
  • Neurologic conditions (dementia, epilepsy, Parkinson disease)
  • Obesity (BMI ≥30 kg/m2) and overweight (BMI 25 to 29 kg/m2), or ≥95th percentile in children
  • Physical inactivity
  • Pregnancy or recent pregnancy
  • Primary immunodeficiencies
  • Smoking (current and former)
  • Sickle cell disease
  • Solid organ or blood stem cell transplantation
  • Substance use disorders
  • Tuberculosis
  • Use of corticosteroids or other immunosuppressive medications
Possible risk factors but evidence is mixed (comorbidities have been associated with severe COVID-19 in at least 1 meta-analysis or systematic review, but other studies had reached different conclusions):
  • Alpha 1 antitrypsin deficiency
  • Bronchopulmonary dysplasia
  • Hepatitis B
  • Hepatitis C
  • Hypertension
  • Thalassemia

ADHD: attention deficit hyperactivity disorder; BMI: body mass index; CDC: Centers for Disease Control and Prevention; COPD: chronic obstructive pulmonary disease; COVID-19: coronavirus disease 2019; HIV: human immunodeficiency virus.

* Listed comorbidities are associated with severe COVID-19 in all adults independent of age. People of color are also at increased risk of severe disease and death, often at a younger age, due to systemic health and social inequities.

¶ Risk of severe disease also rises steadily with age, with more than 93% of deaths occurring among adults ≥50 years and 74% of deaths occurring in adults ≥65 years.

Δ Underlying medical conditions are also associated with severe illness in children, but evidence implicating specific conditions is limited. Children with the following conditions might be at increased risk for severe illness: medical complexity; genetic, neurologic, or metabolic conditions; congenital heart disease; obesity; diabetes; asthma or other chronic lung disease; sickle cell disease; immunosuppression.

References:
  1. Underlying conditions and the higher risk for severe COVID-19. Centers for Disease Control and Prevention. https://www.cdc.gov/covid/hcp/clinical-care/underlying-conditions.html (Accessed on August 21, 2024).
  2. Science brief: Evidence used to update the list of underlying medical conditions that increase a person's risk of severe illness from COVID-19. Centers for Disease Control and Prevention. https://stacks.cdc.gov/view/cdc/106171 (Accessed on August 21, 2024).
  3. Risk for COVID-19 infection, hospitalization, and death by age group. Centers for Disease Control and Prevention. https://stacks.cdc.gov/view/cdc/116835 (Accessed on August 21, 2024).
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