Suggested disease monitoring for infants undergoing treatment for congenital toxoplasmosis

Type of monitoring	Interval	Comments
Serum Toxoplasma-specific IgG and IgM	Every 3 to 6 months until therapy is completed	Repeat serologic testing is particularly important when the initial testing is equivocal
Ophthalmologic examination and vision assessment	Every 3 months until the age of 18 months, then every 6 to 12 months	Perform examination earlier than scheduled if concerning vision or eye symptoms occur Monitoring should continue throughout childhood and adolescence because the risk of developing new or recurrent chorioretinitis persists into adulthood
Detailed neurologic examination	Every 3 to 6 months until 1 to 2 years of age, then as needed	The frequency and duration of neurology follow-up are determined by the presence of neurologic abnormalities
Developmental screening	At the 9-month, 18-month, and 24- or 30-month visits (as is done in children without congenital toxoplasmosis)	Perform screening earlier and/or more frequently if the parent or clinician has concerns about development
Hearing assessments	Perform formal audiology at least once during infancy, then perform audiology screening at ages 4, 5, 6, 8, and 10 years	Perform audiology assessments earlier and/or more frequently if the parent or clinician has concerns about the child's hearing

Ig: immunoglobulin.
* Some experts perform follow-up every 3 to 6 months until the child is old enough to report vision changes reliably.

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