Toxicity | TMZ interruption* | TMZ discontinuation |
Absolute neutrophil count | Greater than or equal to 0.5 and less than 1.5 × 109/L | Less than 0.5 × 109/L |
Platelet count | Greater than or equal to 10 and less than 100 × 109/L | Less than 10 × 109/L |
CTC nonhematological toxicity (except for alopecia, nausea, vomiting) | CTC Grade 2 | CTC Grade 3 or 4 |
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