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خرید پکیج
تعداد آیتم قابل مشاهده باقیمانده : 3 مورد
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Temozolomide dosing modifications during concomitant radiotherapy and temozolomide

Temozolomide dosing modifications during concomitant radiotherapy and temozolomide
Toxicity TMZ interruption* TMZ discontinuation
Absolute neutrophil count Greater than or equal to 0.5 and less than 1.5 × 109/L Less than 0.5 × 109/L
Platelet count Greater than or equal to 10 and less than 100 × 109/L Less than 10 × 109/L
CTC nonhematological toxicity (except for alopecia, nausea, vomiting) CTC Grade 2 CTC Grade 3 or 4
TMZ: temozolomide; CTC: common toxicity criteria.
* Treatment with concomitant TMZ could be continued when all of the following conditions were met: absolute neutrophil count greater than or equal to 1.5 × 109/L; platelet count greater than or equal to 100 × 109/L; CTC nonhematological toxicity less than or equal to Grade 1 (except for alopecia, nausea, vomiting).
Reproduced with permission from: Temozolomide - temozolomide capsule. Copyright © 2020 Accord Healthcare. Available at: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=2d599ccf-8e63-4ff1-aa52-4809744ea97a (Accessed on June 16, 2020).
Graphic 128463 Version 1.0

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