Version November 2024
| Treatment* | Prophylaxis¶ | |
| Term infants with known body weight | ||
| <3 monthsΔ | 3 mg/kg per dose orally twice daily for 5 days | Not recommended except in critical situations◊ |
| 3 through 8 months | 3 mg/kg per dose orally twice daily for 5 days | 3 mg/kg orally once daily |
| 9 through 11 months | 3.5 mg/kg per dose orally twice daily for 5 days | 3.5 mg/kg orally once daily |
| Term infants whose body weight is not known | ||
| Age 0 through 3 monthsΔ | 12 mg orally twice daily for 5 days | Not recommended except in critical situations◊ |
| Age 4 through 5 months | 17 mg orally twice daily for 5 days | 17 mg orally once daily |
| Age 6 through 11 months | 24 mg orally twice daily for 5 days | 24 mg orally once daily |
| Preterm infants | ||
| PMA <28 weeksΔ | Consultation with a specialist in pediatric infectious diseases is recommended | Not recommended except in critical situations◊ |
| PMA 28 through 37 weeks, 6 days | 1 mg/kg per dose orally twice daily for 5 days | |
| PMA 38 through 40 weeks, 0 days | 1.5 mg/kg per dose orally twice daily for 5 days | |
| PMA >40 weeks through 8 months chronologic age | 3 mg/kg per dose orally twice daily for 5 days | |
| Chronologic age 9 months through 11 months | 3.5 mg/kg per dose orally twice daily for 5 days | 3.5 mg/kg per dose orally once daily |
PMA: postmenstrual age (gestational age plus chronologic age).
* The usual duration of treatment is 5 days. Hospitalized patients with severe illness and immunocompromised patients may require an extended course of therapy.
¶ The duration of prophylaxis varies with the clinical circumstances.
Δ Although not part of the US Food and Drug Administration-approved indications, use of oral oseltamivir for treatment of influenza in infants less than 14 days old, and for chemoprophylaxis in infants 3 months to 1 year, is recommended by the American Academy of Pediatrics and Centers for Disease Control and Prevention.[1,2]
◊ Consultation with a specialist in pediatric infectious diseases is recommended.آیا می خواهید مدیلیب را به صفحه اصلی خود اضافه کنید؟
