Trial | Population | N | Design | Results |
MSLT-I[1] | Primary melanoma, clinically node negative | 2001 | Randomized to wide excision alone or wide excision with SLN biopsy and completion dissection for positive SLN |
|
MSLT-II[2] | Patients with SLN metastases | 1939 | Randomized to completion dissection or nodal observation |
|
DeCOG-SLT[3,4] | Patients with SLN metastases | 483 | Randomized to completion dissection or nodal observation |
|
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