Typical magnetic resonance imaging (MRI) patterns in juvenile bulbospinal Alexander disease (juvenile/type II disease)
Typical magnetic resonance imaging (MRI) patterns in juvenile bulbospinal Alexander disease (juvenile/type II disease)
In
the bulbospinal (type II) form that typically presents in juveniles, the
frontal white matter is spared or mildly involved as shown in (A).
Supratentorially, despite the paucity of white matter findings, basal ganglia abnormalities
(B) and a periventricular rim (C) are often present. The most frequent
brainstem finding is a mass lesion in the dorsal medulla, which can be
bilateral as in (D) or unilateral as in (E). The mass lesions may enhance after
gadolinium.
Courtesy of Amy T Waldman, MD.
Graphic 138949 Version 1.0
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