Mandatory | Alerts | Exclusionary | |
Seizures |
|
|
|
EEG |
| ||
Age at onset |
|
| |
Development at onset |
| ||
Neurologic examination |
| ||
Imaging |
| ||
Other testing (eg, genetics) |
| ||
Course of illness |
|
| |
Is MRI or ictal EEG required for diagnosis?
| |||
Possible evolving syndrome: In a child <12 months who presents with a prolonged hemiclonic or bilateral tonic-clonic seizure with fever, and no other underlying cause, the possibility of Dravet syndrome should be considered. Further convulsive seizures (often with fever, and if prolonged or hemiclonic) would allow more definitive diagnosis of Dravet syndrome. A diagnosis would be further supported by the finding of a pathogenic SCN1A variant. | |||
Syndrome without laboratory confirmation: In resource-limited regions, Dravet syndrome can be diagnosed in children without alerts who meet all other clinical mandatory and exclusionary criteria, without EEG, MRI, and genetic testing |
آیا می خواهید مدیلیب را به صفحه اصلی خود اضافه کنید؟